Affinity maturation and hypermutation in a simulation of the humoral immune response

European Journal of Immunology

Volumn 26, Issue 6, 1996, Pages 1350-1358

  Celada, Franco ^a,b   Seiden, Philip E ^c  

^a NYU HOSPITAL FOR JOINT DISEASES   (United States)

^b UNIVERSITY OF GENOA   (Italy)

^c IBM T J WATSON RESEARCH CENTER   (United States)

Author keywords

Affinity maturation; Cell cooperation; Cellular automata; Competition for antigen; Hypermutation

Indexed keywords

ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; CELL MUTANT; COMPLEMENTARITY DETERMINING REGION; HUMORAL IMMUNITY; IMMUNE SYSTEM; IMMUNOSTIMULATION; MUTATION RATE; PRIORITY JOURNAL;

ANTIBODY AFFINITY; ANTIBODY FORMATION; B-LYMPHOCYTES; COMPUTER SIMULATION; GENES, IMMUNOGLOBULIN; LYMPHOCYTE COOPERATION; MODELS, BIOLOGICAL; MUTATION;

EID: 0030026711     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260626     Document Type: Article

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