메뉴 건너뛰기




Volumn 7, Issue 10, 1997, Pages 1327-1330

1-(2-methoxyphenyl)-4-alkylpiperazines: Effect of the N-4 substitutent on the affinity and selectivity for dopamine D4 receptor

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CLOZAPINE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; HALOPERIDOL; NEUROLEPTIC AGENT; PIPERAZINE DERIVATIVE; RECEPTOR SUBTYPE;

EID: 0031579944     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00218-7     Document Type: Article
Times cited : (12)

References (18)
  • 15
    • 0011254965 scopus 로고    scopus 로고
    • All new compounds exhibited satisfactory spectral and elemental analysis data.
    • All new compounds exhibited satisfactory spectral and elemental analysis data.
  • 16
    • 15844382453 scopus 로고    scopus 로고
    • 2) and 100 μL of various concentration of drugs in 1 mL of total volume. The tubes were incubated at 25 °C for 60 minutes and filtered over Whatman GF/C presoaked in P.E.I. 0.3%, then washed two times with 1 mL of ice cold buffer (50 mM Tris·HCl, pH 7.4). Nonspecific binding was determinated in presence of haloperidol 1 μM. Clozapine was used as reference compound.
    • 2) and 100 μL of various concentration of drugs in 1 mL of total volume. The tubes were incubated at 25 °C for 60 minutes and filtered over Whatman GF/C presoaked in P.E.I. 0.3%, then washed two times with 1 mL of ice cold buffer (50 mM Tris·HCl, pH 7.4). Nonspecific binding was determinated in presence of haloperidol 1 μM. Clozapine was used as reference compound.
    • (1996) J. Med. Chem. , vol.39
    • Boyfield, I.1    Brown, T.H.2    Coldwell, M.C.3    Cooper, D.G.4    Hadley, M.S.5    Hagan, J.J.6    Healy, M.A.7    Jones, A.8    King, R.J.9    Middlemiss, D.N.10    Nash, D.J.11    Riley, G.J.12    Scott, E.E.13    Smith, S.A.14    Stemp, G.15
  • 17
    • 0018198399 scopus 로고
    • d = 0.2 nM), 450 μL of diluted rat striatum membranes, 300 mL of various concentration of drugs in 3 mL of total volume. Nonspecific binding was determinated in the presence of haloperidol 1 μM.
    • d = 0.2 nM), 450 μL of diluted rat striatum membranes, 300 mL of various concentration of drugs in 3 mL of total volume. Nonspecific binding was determinated in the presence of haloperidol 1 μM.
    • (1978) Eur. J. Pharmacol. , vol.50 , pp. 283-284
    • Briley, H.1    Langer, S.Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.