Cutting Edge: Immunostimulatory Effects of a Plasmid Expressing CD40 Ligand (CD154) on Gene Immunization

Journal of Immunology

Volumn 159, Issue 12, 1997, Pages 5777-5781

  Mendoza, Robert B ^a   Cantwell, Mark J ^a   Kipps, Thomas J ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BETA GALACTOSIDASE; CD40 ANTIGEN; CD40 LIGAND; DNA VACCINE; IMMUNOLOGICAL ADJUVANT; LIGAND; MEMBRANE PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL CULTURE; CYTOTOXIC T LYMPHOCYTE; DBA MOUSE; FEMALE; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; INTRAMUSCULAR DRUG ADMINISTRATION; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PLASMID; SARCOMA;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; ANTIGENS, CD40; BETA-GALACTOSIDASE; CD40 LIGAND; FEMALE; INJECTIONS, INTRAMUSCULAR; LIGANDS; LYMPHOCYTE ACTIVATION; MAST-CELL SARCOMA; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; PLASMIDS; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION; TUMOR CELLS, CULTURED; VACCINES, DNA;

EID: 0031573541     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Pardoll, D. M., and A. M. Beckerleg. 1995. Exposing the immunology of naked DNA vaccines. Immunity 3:165.
2. McDonnell, W. M., and F. K. Askari. 1996. DNA vaccines. N. Engl. J. Med. 334:42.
3. Donnelly, J. J., A. Friedman, D. Martinez, D. L. Montgomery, J. W. Shiver, S. L. Motzel, J. B. Ulmer, and M. A. Liu. 1995. Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus [see comments]. Nat. Med. 1:583.
4. Gonzalez Armas, J. C., C. S. Morello, L. D. Cranmer, and D. H. Spector. 1996. DNA immunization confers protection against murine cytomegalovirus infection. J. Virol. 70:7921.
5. Fooks, A. R., D. Jeevarajah, A. Warnes, G. W. Wilkinson, and J. C. Clegg. 1996. Immunization of mice with plasmid DNA expressing the measles virus nucleoprotein gene. Viral Immunol. 9:65.
6. Martins, L. P., L. L. Lau, M. S. Asano, and R. Ahmed. 1995. DNA vaccination against persistent viral infection. J. Virol. 69:2574.
7. Watanabe, A., E. Raz, H. Kohsaka, H. Tighe, S. M. Baird, T. J. Kipps, and D. A. Carson. 1993. Induction of antibodies to a kappa variable region by gene immunization. J. Immunol. 151:2871.
8. Raz, E., A. Watanabe, S. M. Baird, R. A. Eisenberg, T. B. Parr, M. Lotz, T. J. Kipps, and D. A. Carson. 1993. Systemic immunological effects of cytokine genes injected into skeletal muscle. Proc. Natl. Acad. Sci. USA 90:4523.
9. Xiang, Z., and H. C. Ertl. 1995. Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 2:129.
10. Kim, J. J., V. Ayyavoo, M. L. Bagarazzi, M. A. Chattergoon, K. Dang, B. Wang, J. D. Boyer, and D. B. Weiner. 1997. In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen. J. Immunol. 158:816.
11. Iwasaki, A., B. J. Stiernholm, A. K. Chan, N. L. Berinstein, and B. H. Barber. 1997. Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines. J. Immunol. 158:4591.
12. Tsuji, T., K. Hamajima, N. Ishii, I. Aoki, J. Fukushima, K. Q. Xin, S. Kawamoto, S. Sasaki, K. Matsunaga, Y. Ishigatsubo, K. Tani, T. Okubo, and K. Okuda. 1997. Immunomodulatory effects of a plasmid expressing B7-2 on human immunodeficiency virus-1-specific cell-mediated immunity induced by a plasmid encoding the viral antigen. Eur. J. Immunol. 27:782.
13. Linsley, P. S., and J. A. Ledbetter. 1993. The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11:191.
14. Corr, M., D. J. Lee, D. A. Carson, and H. Tighe. 1996. Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J. Exp. Med. 184:1555.
15. Armitage, R. J., W. C. Fanslow, L. Strockbine, T. A. Sato, K. N. Clifford, B. M. Macduff, D. M. Anderson, S. D. Gimpel, T. Davis-Smith, C. R. Maliszewski, E. A. Clark, C. A. Smith, K. H. Grabstein, D. Cosman, and M. K. Spriggs. 1992. Molecular and biological characterization of a murine ligand for CD40. Nature 357:80.
16. + T cells. J. Immunol. 151:2497.
17. Castle, B. E., K. Kishimoto, C. Stearns, M. L. Brown, and M. R. Kehry. 1993. Regulation of expression of the ligand for CD40 on T helper lymphocytes. J. Immunol. 151:1777.
18. Cantwell, M. J., T. Hua, J. Pappas, and T. J. Kipps. 1997. Acquired CD40-ligand deficiency in chronic lymphocytic leukemia. Nat. Med. 3:984.
19. Ranheim, E. A., and T. J. Kipps. 1993. Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal. J. Exp. Med. 177:925.
20. Lederman, S., M. J. Yellin, G. Inghirami, J. J. Lee, D. M. Knowles, and L. Chess. 1992. Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles: roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help. J. Immunol. 149:3817.
21. van Kooten, C., and J. Banchereau. 1996. CD40-CD40 ligand: a multifunctional receptor-ligand pair. Adv. Immunol. 61:1.
22. + hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J. Exp. Med. 185:341.
23. Carbone, F. R., and M. J. Bevan. 1990. Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo. J. Exp. Med. 171:377.
24. Yamamoto, T., S. Yamamoto, T. Kataoka, and T. Tokunaga. 1994. Ability of oligonucleotides with certain palindromes to induce interferon production and augment natural killer cell activity is associated with their base length. Antisense Res. Dev. 4:119.
25. Krieg, A. M., A. K. Yi, S. Matson, T. J. Waldschmidt, G. A. Bishop, R. Teasdale, G. A. Koretzky, and D. M. Klinman. 1995. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374:546.
26. Klinman, D. M., G. Yamshchikov, and Y. Ishigatsubo. 1997. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 158:3635.
27. Sato, Y., M. Roman, H. Tighe, D. Lee, M. Corr, M. D. Nguyen, G. J. Silverman, M. Lotz, D. A. Carson, and E. Raz. 1996. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 273:352.
28. Finkelman, F. D., J. Holmes, I. M. Katona, J. F. Urban, Jr., M. P. Beckmann, L. S. Park, K. A. Schooley, R. L. Coffman, T. R. Mosmann, and W. E. Paul. 1990. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol 8:303.
29. Rizzo, L. V., R. H. DeKruyff, D. T. Umetsu, and R. R. Caspi. 1995. Regulation of the interaction between Th1 and Th2 T cell clones to provide help for antibody production in vivo. Eur. J. Immunol. 25:708.