DNA immunization confers protection against murine cytomegalovirus infection

Journal of Virology

Volumn 70, Issue 11, 1996, Pages 7921-7928

  González Armas, Juan Carlos ^a   Morello, Christopher S ^b   Cranmer, Lee D ^a   Spector, Deborah H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; IMMEDIATE EARLY PROTEIN; PLASMID DNA; VIRUS PHOSPHOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN 3T3; CELL STRAIN COS1; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC T LYMPHOCYTE; ENHANCER REGION; FEMALE; IMMEDIATE EARLY GENE; IMMUNIZATION; INTRADERMAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SEROCONVERSION; VACCINATION; VIRUS INHIBITION;

EID: 0001147878     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.11.7921-7928.1996     Document Type: Article

References (43)

1. Acsadi, G., G. Dickson, D. R. Love, A. Jani, F. S. Walsh, A. Gurusinghe, J. A. Wolff, and K. E. Davies. 1991. Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs. Nature (London) 352:815-818.
2. Aida, Y., and M. J. Pabst. 1990. Removal of endotoxin from protein solutions by phase separation using Triton X-114. J. Imnumol. Methods 132:191-195.
3. Barry, M. A., W. C. Lai, and S. A. Johnston. 1995. Protection against mycoplasma infection using expression-library immunization. Nature (London) 377:632-635.
4. Bourne, N., L. R. Stanherry, D. I. Bernstein, and D. Lew. 1996. DNA immunization against experimental genital herpes simplex virus infection. J. Infect. Dis. 173:800-807.
5. Bruggeman, C. A. 1993. Cytomegalovirus and latency: an overview. Virchows Arch. B 64:325-333.
6. Cooney, E. L., A. C. Collier, P. D. Greenberg, R. W. Coombs, J. Zarling, D. E. Arditti, M. C. Hoffman, S. L. Hu, and L. Corey. 1991. Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein. Lancet 337:567-572.
7. Cox, G. J., T. J. Zamb, and L. A. Babiuk. 1993. Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA. J. Virol. 67:5664-5667.
8. Cranmer, L. D., C. Clark, and D. H. Spector. 1994. Cloning, characterization, and expression of the murine cytomegalovirus homologue of the human cytomegalovirus 28-kDa matrix phosphoprotein (UL99). Virology 205:417-421.
9. Del Val, M., H. Volkmer, J. B. Rothbard, S. Jonjić, M. Messerle, J. Schickedanz, M. J. Reddehase, and U. H. Koszinowski. 1988. Molecular basis for cylolylic T-lymphocyte recognition of the murine cytomegalovirus immediate-early protein pp89. J. Virol. 62:3965-3972.
10. Elliott, R., C. Clark, D. Jaquish, and D. H. Speclor. 1991. Transcription analysis and sequence of the putative murine cytomegalovirus DNA polymerase gene. Virology 185:169-186.
11. Fynan, E. F., R. G. Webster, D. H. Fuller, J. R. Haynes, J. C. Santoro, and H. L. Robinson. 1993. DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. Proc. Natl. Acad. Sci. USA 90: 11478-11482.
12. Gascan, H., J. F. Gauchat, M. G. Roncarolo, H. Yssel, H. Spits, and J. E. de Vries. 1991. Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones. J. Exp. Med. 173:747-750.
13. Ghiasi, H., S. Cai, S. Slanina, A. B. Nesburn, and S. L. Wechsler. 1995. Vaccination of mice with herpes simplex virus type I glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge. Antiviral Res. 28:147-157.
14. Ho, M. 1992. Cytomegalovirus biology and infection, 2nd ed. Plenum Publishing Co., New York.
15. Jonjić, S., M. del Val, G. M. Keil, M. J. Reddehase, and U. H. Koszinowski. 1988. A nonstructural viral protein expressed by a recombinant vaccinia virus protects against lethal cytomegalovirus infection. J. Virol. 62:1653-1658.
16. + T lymphocytes. J. Virol. 64:5457-5464.
17. Koszinowski, U. H., G. M. Keil, H. Schwarz, J. Schickedanz, and M. J. Reddehase. 1987. A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolylic T lymphocytes. J. Exp. Med. 166:289-294.
18. Koszinowski, U. H., M. J. Reddehase, G. M. Keil, and J. Schickedanz. 1987. Host immune response to cytomegalovirus: products of transfected viral immediate-early genes are recognized by cloned cytolytic T lymphocytes. J. Virol. 61:2054-2058.
19. Koszinowski, U. H., M. J. Reddehase, G. M. Keil, H. Volkmer, S. Jonjic, M. Messerle, M. del Val, W. Mutter, K. Munch, and B. Buhler. 1987. Molecular analysis of herpesviral gene products recognized by protective cytolytic T lymphocytes. Immunol. Lett. 16:185-192.
20. Manickan, E. R., J. D. Rouse, Z. Yu, W. S. Wire, and B. T. Rouse. 1995. Genetic immunization against herpes simplex virus. Protection is mediated by CD4 T lymphocytes. J. Immunol. 155:259-265.
21. Mercer, J. A., and D. H. Spector. 1986. Pathogenesis of acute murine cytomegalovirus infection in resistant and susceptible strains of mice. J. Virol. 57:497-504.
22. Meyers, J. D. 1984. Cytomegalovirus infection following marrow transplantation: risk, treatment, and prevention. Birth Defects Orig. Artic. Ser. 20: 101-117.
23. Mor, G., D. M. Klinman, S. Shapiro, E. Hagiwara, M. Sedegah, J. A. Norman, S. L. Huffman, and A. D. Steinberg. 1995. Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA. J. Immunol. 155:2039-2046.
24. Pedroza Martins, L., L. L. Lau, M. S. Asano, and R. Ahmed. 1995. DNA vaccination against persistent viral infection. J. Virol. 69:2574-2582.
25. Quinnan, G., Jr., N. Kirmani, A. H. Rook, J. F. Manischewitz, L. Jackson, G. Moreschi, G. W. Santos, R. Saral, and W. H. Burns. 1982. Cytotoxic T cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients. N. Engl. J. Med. 307:7-13.
26. Quinnan, G. V., J. F. Manischewitz, and F. A. Ennis. 1978. Cytotoxic T lymphocyte response to murine cytomegalovirus infection. Nature (London) 273:541-543.
27. Raz, E., D. A. Carson, S. E. Parker, T. B. Parr, A. M. Ahai, G. Aichinger, S. H. Gromkowski, M. Singh, D. Lew, M. A. Yankauckas, S. M. Baird, and G. H. Rhodes. 1994. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Natl. Acad. Sci. USA 91:9519-9123.
28. Reddehase, M. J., and U. H. Koszinowski. 1984. Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection. Nature (London) 312:369-371.
29. Reddehase, M. J., W. Mutter, K. Munch, H. J. Buhring, and U. H. Koszinowski. 1987. CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity. J. Virol. 61: 3102-3108.
30. Reddehase, M. J., J. B. Rothbard, and U. H. Koszinowski. 1989. A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes. Nature (London) 337:651-653.
31. Reddehase, M. J., F. Weiland, K. Münch, S. Jonjic, A. Lüske, and U. H. Koszinowski. 1985. Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs. J. Virol. 55:264-273.
32. Robinson, H. L., L. A. Hunt, and R. G. Webster, 1993. Protection against a lethal influenza virus challenge by immunization with a haemagglutininexpressing plasmid DNA. Vaccine 11:957-960.
33. Schirmbeck, R., K. Bohm, K. Ando, F. V. Chisari, and J. Reimann. 1995. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice. J. Virol. 69:5929-5934.
34. Staczek, J. 1990. Animal cytomegaloviruses. Microbiol. Rev. 54:247-265.
35. Staprans, S. I., D. K. Rabert, and D. H. Spector. 1988. Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene. J. Virol. 62:3463-3473.
36. Steinman, R. M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. lmmunol. 9:271-296.
37. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
38. Ulmer, J. B., J. J. Donnelly, S. E. Parker, G. H. Rhodes, P. L. Feigner, V. J. Dwarki, S. H. Gromkowski, R. R. Deck, C. M. DeWitt, A. Friedman, L. A. Hawe, K. R. Leander, D. Martinez, H. C. Perry, J. W. Shiver, D. L. Montgomery, and M. A. Liu. 1993. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259:1745-1749.
39. Vandekerckhove, B. A., D. Jones, J. Punnonen, D. Schols, H. C. Lin, B. Duncan, R. Bacchetta, J. E. de Vries, and M. G. Roncarolo. 1993. Human Ig production and isotype switching in severe combined immunodeficiency-human mice. J. Immunol. 151:128-137.
40. Volkmer, H., C. Bertholet, S. Jonjic, R. Wittek, and U. H. Koszinowski. 1987. Cytolytic T lymphocyte recognition of the murine cytomegalovirus nonstructural immediate-early protein pp89 expressed by recombinant vaccinia virus. J. Exp. Med. 166:668-677. (Erratum, 166:1609.)
41. Wolff, J. A., R. W. Malone, P. Williams, W. Chong, G. Acsadi, A. Jani, and P. L. Feigner. 1990. Direct gene transfer into mouse muscle in vivo. Science 247:1465-1468.
42. Xiang, Z. Q., S. Spitalnik, M. Tran, W. H. Wunner, J. Cheng, and H. C. Ertl. 1994. Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus. Virology 199: 132-140.
43. Yokoyama, M., J. Zhang, and J. L. Whitton. 1995. DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection. J. Virol. 69:2684-2688.