-
1
-
-
0027177008
-
IL-12: Initiation cytokine for cell-mediated immunity
-
Scott, P. 1993. IL-12: initiation cytokine for cell-mediated immunity. Science 260:496.
-
(1993)
Science
, vol.260
, pp. 496
-
-
Scott, P.1
-
2
-
-
0023726937
-
Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
-
Gajewski, T. F., and F. W. Fitch. 1488. Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J. Immunol. 140:4245.
-
(1488)
J. Immunol.
, vol.140
, pp. 4245
-
-
Gajewski, T.F.1
Fitch, F.W.2
-
3
-
-
0024408824
-
Two types of mouse T helper cells. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
Fiorentino, D. F., M. W. Bond, and T. R. Mosmann. 1989. Two types of mouse T helper cells. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170:2081.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 2081
-
-
Fiorentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
4
-
-
0025818157
-
Helper T-cell subsets in mouse leishmaniasis: Induction, expansion and effector function
-
Locksley, R. M., and P. Scott. 1991. Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function. Immunol. Today 12:A58.
-
(1991)
Immunol. Today
, vol.12
-
-
Locksley, R.M.1
Scott, P.2
-
5
-
-
0021884545
-
An H-11-linked gene has a parallel effect on L. major and L. donovani infections in mice
-
Blackwell, J. M., C. Hale, M. B. Roberts, O. M. Ulczak, F. Y. Liew, and J. G. Howard. 1985. An H-11-linked gene has a parallel effect on L. major and L. donovani infections in mice. Immunogenetics 21:385.
-
(1985)
Immunogenetics
, vol.21
, pp. 385
-
-
Blackwell, J.M.1
Hale, C.2
Roberts, M.B.3
Ulczak, O.M.4
Liew, F.Y.5
Howard, J.G.6
-
6
-
-
0019788887
-
Single gene control of resistance to cutaneous leishmaniasis in mice
-
DeTolla, L. J., P. A. Scott, and J. P. Farrell. 1981. Single gene control of resistance to cutaneous leishmaniasis in mice. Immunogenetics 14:29.
-
(1981)
Immunogenetics
, vol.14
, pp. 29
-
-
DeTolla, L.J.1
Scott, P.A.2
Farrell, J.P.3
-
7
-
-
0027422394
-
Genetic control of Leishmania major infection in congenic, recombinant inbred and F2 populations of mice
-
Mock, B., J. Blackwell, J. Hilgers, M. Potter, and C. Nacy. 1983. Genetic control of Leishmania major infection in congenic, recombinant inbred and F2 populations of mice. Eur. J. Immunogen. 20:335.
-
(1983)
Eur. J. Immunogen.
, vol.20
, pp. 335
-
-
Mock, B.1
Blackwell, J.2
Hilgers, J.3
Potter, M.4
Nacy, C.5
-
8
-
-
0027485741
-
Mapping of genes controlling Leishmania major infection in CXS recombinant mice
-
Roberts, M., B. A. Mock, and J. M. Blackwell. 1997. Mapping of genes controlling Leishmania major infection in CXS recombinant mice. Eur. J. Immunogen. 20:349.
-
(1997)
Eur. J. Immunogen.
, vol.20
, pp. 349
-
-
Roberts, M.1
Mock, B.A.2
Blackwell, J.M.3
-
9
-
-
0025222698
-
1L-4 directs the development of Th2-like helper effectors
-
Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. 1L-4 directs the development of Th2-like helper effectors. J. Immunol. 145:3796.
-
(1990)
J. Immunol.
, vol.145
, pp. 3796
-
-
Swain, S.L.1
Weinberg, A.D.2
English, M.3
Huston, G.4
-
10
-
-
0026500979
-
IL-4 induces a Th2 response in Leishmania mojor-infected mice
-
Chatelain, R., K. Varkila, and R. L. Coffman. 1992. IL-4 induces a Th2 response in Leishmania mojor-infected mice. J. Immunol. 148:1182.
-
(1992)
J. Immunol.
, vol.148
, pp. 1182
-
-
Chatelain, R.1
Varkila, K.2
Coffman, R.L.3
-
11
-
-
0026648380
-
Differential regulation of T helper phenotype development by interleukins 4 and 10 in an α,β T-cell-receptor transgenic system
-
Hsieh, C.-S., A. B. Heimberger, J. S. Gold, A. O'Garra, and K. M. Murphy. 1992. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an α,β T-cell-receptor transgenic system. Proc. Natl. Acad. Sci. USA 89: 6065.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6065
-
-
Hsieh, C.-S.1
Heimberger, A.B.2
Gold, J.S.3
O'Garra, A.4
Murphy, K.M.5
-
13
-
-
0025951644
-
Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
-
Swain, S. L., G. Huston, S. Tonkonogy, and A. Weinberg. 1991. Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 147:2991.
-
(1991)
J. Immunol.
, vol.147
, pp. 2991
-
-
Swain, S.L.1
Huston, G.2
Tonkonogy, S.3
Weinberg, A.4
-
15
-
-
0028049247
-
The adjuvant effect of interleukin-12 in a vaccine against Leishmania major
-
Afonso, L. C. C., T. M. Scharton, L. Q. Vieira, M. Wysocka, G. Trinchieri, and P. Scott. 1994. The adjuvant effect of interleukin-12 in a vaccine against Leishmania major. Science 263:235.
-
(1994)
Science
, vol.263
, pp. 235
-
-
Afonso, L.C.C.1
Scharton, T.M.2
Vieira, L.Q.3
Wysocka, M.4
Trinchieri, G.5
Scott, P.6
-
16
-
-
0028329177
-
Effects of IL-12 on helper T cell-dependent immune responses in vivo
-
McKnight, A. J., G. J. Zimmer, I. Fogelman, S. F. Wolf, and A. K. Abbas. 1994. Effects of IL-12 on helper T cell-dependent immune responses in vivo. J. Immunol. 152:2172.
-
(1994)
J. Immunol.
, vol.152
, pp. 2172
-
-
McKnight, A.J.1
Zimmer, G.J.2
Fogelman, I.3
Wolf, S.F.4
Abbas, A.K.5
-
17
-
-
0027409793
-
Natural killer cell stimulatory factor (NKSF/IL-12) induces Th1-type specific immune responses and inhibits the development of IL-4 producing Th cells
-
Manetti, R., P. Parronchi, M. G. Giudizi, M.-P. Piccinni, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (NKSF/IL-12) induces Th1-type specific immune responses and inhibits the development of IL-4 producing Th cells. J. Exp. Med. 177:1199.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1199
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
Piccinni, M.-P.4
Maggi, E.5
Trinchieri, G.6
Romagnani, S.7
-
18
-
-
0027144089
-
Regulatory role of IL-4 and other cytokines in the function and development of human T cell clones
-
Romagnani, S. 1993. Regulatory role of IL-4 and other cytokines in the function and development of human T cell clones. Res. Immunol. 144:625.
-
(1993)
Res. Immunol.
, vol.144
, pp. 625
-
-
Romagnani, S.1
-
19
-
-
0028107189
-
Differential effects of IL-12 on the development of naive mouse CD4(+) T cells
-
Schmitt, E., P. Hoehm, T. Germann, and E. Rude. 1994. Differential effects of IL-12 on the development of naive mouse CD4(+) T cells. Eur. J. Immunol. 24:343.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 343
-
-
Schmitt, E.1
Hoehm, P.2
Germann, T.3
Rude, E.4
-
20
-
-
0011191015
-
In vitro maturation of human neonatal CD4 T lymphocytes. I. Induction of IL-4-producing cells after long term culture in the presence of IL-4 plus either IL-2 or IL-12
-
Wu, C. Y., C. E. Demeure, M. Gately, F. Podlaski, M. Kiniwa, and G. Delespesse. 1994. In vitro maturation of human neonatal CD4 T lymphocytes. I. Induction of IL-4-producing cells after long term culture in the presence of IL-4 plus either IL-2 or IL-12. J. Immunol. 152:1141.
-
(1994)
J. Immunol.
, vol.152
, pp. 1141
-
-
Wu, C.Y.1
Demeure, C.E.2
Gately, M.3
Podlaski, F.4
Kiniwa, M.5
Delespesse, G.6
-
22
-
-
0027528795
-
Recombinant Interleukin 12 cures mice infected with Leishmania major
-
Heinzel, F. P., D. S. Schoenhaut, R. M. Rerko, L. E. Rosser, and M. K. Gately. 1993. Recombinant Interleukin 12 cures mice infected with Leishmania major. J. Exp. Med. 177:1505.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1505
-
-
Heinzel, F.P.1
Schoenhaut, D.S.2
Rerko, R.M.3
Rosser, L.E.4
Gately, M.K.5
-
23
-
-
0027309318
-
Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective Th1 immune response
-
Sypek, J. P., C. L. Chung, S. E. H. Mayor, J. M. Subramanyam, S. J. Goldman, D. S. Sieburth, S. F. Wolf, and R. G. Schaub. 1993. Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective Th1 immune response. J. Exp. Med. 177:1797.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1797
-
-
Sypek, J.P.1
Chung, C.L.2
Mayor, S.E.H.3
Subramanyam, J.M.4
Goldman, S.J.5
Sieburth, D.S.6
Wolf, S.F.7
Schaub, R.G.8
-
24
-
-
0025133974
-
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody: Evidence for a T cell-dependent, interferon gamma-independent mechanism
-
Sadick, M. D., F. P. Heinzel, B. J. Holaday, R. T. Pu, R. S. Dawkins, and R. M. Locksley. 1990. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody: evidence for a T cell-dependent, interferon gamma-independent mechanism. J. Exp. Med. 171:115.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 115
-
-
Sadick, M.D.1
Heinzel, F.P.2
Holaday, B.J.3
Pu, R.T.4
Dawkins, R.S.5
Locksley, R.M.6
-
25
-
-
0024412797
-
Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major
-
Belosevic, M., D. S. Finbloom, P. H. Van Der Meide, M. V. Slayter, and C. A. Nacy. 1989. Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major. J. Immunol. 143:266.
-
(1989)
J. Immunol.
, vol.143
, pp. 266
-
-
Belosevic, M.1
Finbloom, D.S.2
Van Der Meide, P.H.3
Slayter, M.V.4
Nacy, C.A.5
-
26
-
-
0026056142
-
IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis
-
Scott, P. 1991. IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147:3149.
-
(1991)
J. Immunol.
, vol.147
, pp. 3149
-
-
Scott, P.1
-
27
-
-
0029077326
-
IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
-
Scharton-Kersten, T., L. C. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1995. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154:5320.
-
(1995)
J. Immunol.
, vol.154
, pp. 5320
-
-
Scharton-Kersten, T.1
Afonso, L.C.C.2
Wysocka, M.3
Trinchieri, G.4
Scott, P.5
-
28
-
-
0029076809
-
Endogenous IL-12 is required for control of Th2 cytokine responses
-
Heinzel, F. P., R. M. Rerko, F. Ahmed, and E. Pearlman. 1995. Endogenous IL-12 is required for control of Th2 cytokine responses. J. Immunol. 155:730.
-
(1995)
J. Immunol.
, vol.155
, pp. 730
-
-
Heinzel, F.P.1
Rerko, R.M.2
Ahmed, F.3
Pearlman, E.4
-
31
-
-
0027199519
-
Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo
-
Powrie, F., S. M. Menon, and R. L. Coffman. 1993. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur. J. Immunol. 23:3043.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 3043
-
-
Powrie, F.1
Menon, S.M.2
Coffman, R.L.3
-
32
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
33
-
-
0028934155
-
Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin-12 and pentostam
-
Nabors, G. S., L. C. C. Afonso, J. P. Farrell, and P. Scott. 1995. Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin-12 and pentostam. Proc. Natl. Acad. Sci. USA 92:3142.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3142
-
-
Nabors, G.S.1
Afonso, L.C.C.2
Farrell, J.P.3
Scott, P.4
-
34
-
-
0021320759
-
Identification of an infective stage of Leishmania promastigotes
-
Sacks, D. H., and P. V. Perkins. 1984. Identification of an infective stage of Leishmania promastigotes. Science 223:1417.
-
(1984)
Science
, vol.223
, pp. 1417
-
-
Sacks, D.H.1
Perkins, P.V.2
-
35
-
-
0023257259
-
Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes
-
Scott, P., E. Pearce, P. Natovitz, and A. Sher. 1987. Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes. J. Immunol. 139:221.
-
(1987)
J. Immunol.
, vol.139
, pp. 221
-
-
Scott, P.1
Pearce, E.2
Natovitz, P.3
Sher, A.4
-
36
-
-
0027514888
-
Constructing polycompetitor cDNAs for quantitative PCR
-
Reiner, S. L., S. Zheng, D. B. Corry, and R. M. Locksley. 1993. Constructing polycompetitor cDNAs for quantitative PCR. J. Immunol. Methods 165:37.
-
(1993)
J. Immunol. Methods
, vol.165
, pp. 37
-
-
Reiner, S.L.1
Zheng, S.2
Corry, D.B.3
Locksley, R.M.4
-
37
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyante-phenol-chloroform extraction
-
Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyante-phenol-chloroform extraction. Anal. Biochem. 162: 156.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156
-
-
Chomczynski, P.1
Sacchi, N.2
-
38
-
-
0024545506
-
Specific assays for cytokine production by T cells
-
Mosmann, T. R., and T. A. T. Fong. 1989. Specific assays for cytokine production by T cells. J. Immunol. Methods 116:151.
-
(1989)
J. Immunol. Methods
, vol.116
, pp. 151
-
-
Mosmann, T.R.1
Fong, T.A.T.2
-
39
-
-
0026781801
-
Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major
-
Bretscher, P. A., G. Wei, J. N. Menon, and H. Bielefeldt-Ohmann. 1992. Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major. Science 257:539.
-
(1992)
Science
, vol.257
, pp. 539
-
-
Bretscher, P.A.1
Wei, G.2
Menon, J.N.3
Bielefeldt-Ohmann, H.4
-
40
-
-
0029847368
-
Functional diversity of helper T lymphocytes
-
Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
-
(1996)
Nature
, vol.383
, pp. 787
-
-
Abbas, A.K.1
Murphy, K.M.2
Sher, A.3
-
41
-
-
0027199519
-
Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo
-
Powrie, F., S. Menon, and R. L. Coffman. 1993. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur. J. Immunol. 23:3043.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 3043
-
-
Powrie, F.1
Menon, S.2
Coffman, R.L.3
-
42
-
-
0028067787
-
+ T cells to C.B-17 SCID mice: A model to study Th1 and Th2 cell differentiation and regulation in vivo
-
+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo. Res. Immunol. 145:347.
-
(1994)
Res. Immunol.
, vol.145
, pp. 347
-
-
Powrie, F.1
Coffman, R.L.2
Correa-Oliveira, R.3
-
43
-
-
0028962552
-
Induction of a Th2 population from a polarized Leishmania-speciftc Th1 population by in vitro culture with IL-4
-
Mocci, S., and R. L. Coffman. 1995. Induction of a Th2 population from a polarized Leishmania-speciftc Th1 population by in vitro culture with IL-4. J. Immunol. 154:3779.
-
(1995)
J. Immunol.
, vol.154
, pp. 3779
-
-
Mocci, S.1
Coffman, R.L.2
-
44
-
-
0028931038
-
+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type
-
+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type. J. Exp. Med. 181:1081.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1081
-
-
Secrist, H.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
45
-
-
0029609052
-
The role of IL-12 in modulating an established Th2 response in experimental leishmaniasis
-
Hondowicz, B., and P. Scott. 1996. The role of IL-12 in modulating an established Th2 response in experimental leishmaniasis. Res. Immunol. 146:560.
-
(1996)
Res. Immunol.
, vol.146
, pp. 560
-
-
Hondowicz, B.1
Scott, P.2
-
46
-
-
0028129526
-
Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
-
Stenger, S., H. Thuring, M. Rollinghoff, and C. Bogdan. 1994. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180:783.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 783
-
-
Stenger, S.1
Thuring, H.2
Rollinghoff, M.3
Bogdan, C.4
-
47
-
-
0023123634
-
Experimental cutaneous leishmaniasis. II. A possible role for prostaglandins in exacerbation of disease in Leishmania major-infected BALB/c mice
-
Farrell, J. P., and C. P. Kirkpatrick. 1987. Experimental cutaneous leishmaniasis. II. A possible role for prostaglandins in exacerbation of disease in Leishmania major-infected BALB/c mice. J. Immunol. 138:902.
-
(1987)
J. Immunol.
, vol.138
, pp. 902
-
-
Farrell, J.P.1
Kirkpatrick, C.P.2
-
48
-
-
0029071483
-
Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
-
Szabo, S. L., N. G. Jacobson, A. S. Dighe, U. Gubler, and K. H. Murphy. 1995. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity 2:665.
-
(1995)
Immunity
, vol.2
, pp. 665
-
-
Szabo, S.L.1
Jacobson, N.G.2
Dighe, A.S.3
Gubler, U.4
Murphy, K.H.5
-
49
-
-
0030042868
-
Genetic susceptibility to Leishmania: IL-12 responsiveness in Th1 cell development
-
Guler, M. L., J. D. Gorham, C.-S. Hsieh, A. J. Mackey, R. G. Steen, W. F. Dietrich, and K. M. Murphy. 1996. Genetic susceptibility to Leishmania: IL-12 responsiveness in Th1 cell development. Science 271:984.
-
(1996)
Science
, vol.271
, pp. 984
-
-
Guler, M.L.1
Gorham, J.D.2
Hsieh, C.-S.3
Mackey, A.J.4
Steen, R.G.5
Dietrich, W.F.6
Murphy, K.M.7
-
50
-
-
0029613296
-
Regulation of interleukin-12 signal transduction during T helper cell phenotype development
-
Jacobson, N. G., S. J. Szabo, M. L. Guler, J. D. Gorham, and K. M. Murphy. 1996. Regulation of interleukin-12 signal transduction during T helper cell phenotype development. Res. Immunol. 146:446.
-
(1996)
Res. Immunol.
, vol.146
, pp. 446
-
-
Jacobson, N.G.1
Szabo, S.J.2
Guler, M.L.3
Gorham, J.D.4
Murphy, K.M.5
|