MAPPING OF GENES CONTROLLING LEISHMANIA MAJOR INFECTION IN CXS RECOMBINANT INBRED MICE

International Journal of Immunogenetics

Volumn 20, Issue 5, 1993, Pages 349-362

  Roberts, M ^a   Mock, B A ^b   Blackwell, J M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME 11; DISEASE COURSE; FEMALE; GENE LOCATION; GENE MAPPING; GENETIC REGULATION; INBRED STRAIN; INFECTION CONTROL; LEISHMANIA MAJOR; LEISHMANIASIS; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMASTIGOTE;

ANIMAL; CHROMOSOME MAPPING; FEMALE; GENETIC MARKERS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LINKAGE (GENETICS); MALE; MICE; MICE, INBRED BALB C; PHENOTYPE; RECOMBINATION, GENETIC; SUPPORT, NON-U.S. GOV'T; TIME FACTORS;

EID: 0027485741     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.1993.tb00154.x     Document Type: Article

References (36)

1. Genetic control of discrete phases of complex infections: Leishmania donovani as a model
2. Protozoan infections
3. Mapping the gene controlling susceptibility to cutaneous leishmaniasis
4. Response of BALB/c mice to leishmanial infection
5. Mouse chromosome 11
6. Expression of a monocyte chemotactic cytokine by human mononuclear phagocytes
7. Monoclonal antibodies that recognise distinct epitopes of the macrophage type three complement receptor differ in their ability to inhibit binding of Leishmania promastigotes harvested at different phases of their growth cycle
8. Differences in Lsh gene control over systemic Leishmania major and L. donovani or L. mexicana mexicana infections are due to differential targeting to infiltrating versus resident liver macrophage populations
9. The Il‐4 gene maps to chromosome 11, near the gene encoding 11‐3
10. Single gene control of resistance to cutaneous leishmaniasis in mice
11. Intracellular replication of Leishmania tropica in mouse peritoneal macrophages: amastigote infection of resident cells and inflammatory exidate macrophages
12. Reciprocal expression of interferon‐gamma or interleukin 4 during resolution or progression of murine leishmaniasis. Evidence for expansion of distinct T helper T cell subsets
13. Strain distribution patterns of genetic polymorphism between BALB/cHeA and STS/A strains
14. A series of recombinant inbred strains between the BALB/cHeA and STS/A mouse strains
15. Immunological regulation of experimental cutaneous leishmaniasis. I. Immunogenetic aspects of susceptibility to Leishmania tropica in mice
16. Susceptibility to murine cutaneous leishmaniasis correlates with the capacity to generate interleukin 3 in response to Leishmania antigen in vitro
17. Analysis of host protective and disease promoting cells
18. Murine cutaneous leishmaniasis: susceptibility correlated with differential expansion of helper T cell subsets
19. Differential regulation of interleukin‐6, macrophage inflammatory protein‐1, and JE/MCP‐1 cytokine expression in macrophage cell lines
20. Increased myelopoiesis during L. major infection in mice. Generation of ‘safe targets’ as a possible way to evade the effector immune mechanisms
21. Discriminant function analysis of genetic traits associated with Leishmania major infection in the CXS recombinant inbred strains
22. Genetic control of Leishmania major infection in congenic, recombinant inbred and F2 populations of mice
23. A model for the mechanism of sensitivity of BALB/c mice to L. major and premunition in leishmaniasis
24. Chemotherapy and cutaneous leishmaniasis: Leishmania tropica infection in mice
25. Properties of the novel proinflammatory supergene ‘intercrine’ cytokine family
26. Influence of Lsh, H‐2, and an H‐II‐linked gene on visceralisation and metastasis associated with Leishmania mexicana infection in mice
27. Genetic analysis of Leishmania mexicana infection in mice: single gene (Scl‐2) controlled predisposition to cutaneous lesion development
28. Murine cutaneous leishmaniasis resistance correlates with the capacity to generate interferon‐gamma in response to antileishmanial antigens in vitro
29. Biology of the RANTES/Sis cytokine family
30. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
31. Host resistance to the Khartoum strain of Leishmania donovani
32. Recombinant inbred strains; use in mapping
33. Clustering of cytokine genes on mouse chromosome 11
34. Human monocyte chemoattractant protein‐1 (MCP‐1): full length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes and sequence similarity to mouse competence gene JE
35. Gene regulation in macrophage activation: differential regulation of genes encoding for tumour necrosis factor, interleukin‐1, JE and KC by interferon‐γ and lipopolysaccharide