CD44 Regulates Phagocytosis of Apoptotic Neutrophil Granulocytes, but Not Apoptotic Lymphocytes, by Human Macrophages

Journal of Immunology

Volumn 159, Issue 2, 1997, Pages 919-925

  Hart, Simon P ^a   Dougherty, Graeme J ^b   Haslett, Christopher ^a   Dransfield, Ian ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN;

APOPTOSIS; ARTICLE; CELL CULTURE; COCULTURE; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; LYMPHOCYTE; MACROPHAGE; NEUTROPHIL; PATHOLOGY; PHAGOCYTOSIS;

ANTIGENS, CD44; APOPTOSIS; CELLS, CULTURED; COCULTURE TECHNIQUES; FLOW CYTOMETRY; HUMANS; LYMPHOCYTES; MACROPHAGES; NEUTROPHILS; PHAGOCYTOSIS;

EID: 0031570880     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Lesley, J., R Hyman, and P. W. Kincade. 1993. CD44 and its interaction with the extracellular matrix. Adv. Immunol. 54:271.
2. Henke, C. A., V. Roongta, D. J. Mickelson, J. R. Knutson, and J. B. McCarthy. 1996. CD44-relaled chondroitin sulfate proteoglycan, a cell surface receptor implicated with tumor cell invasion, mediates endothelial cell migration on fibrinogen and invasion into a fibrin matrix. J. Clin. Invest. 97:2541.
3. Screaton, G. R., M. V. Bell, D. G. Jackson, H. B. Cornelis, U. Gerth, and J. I. Bell. 1992. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci. USA 89:12160.
4. Levesque, M. C., and B. F. Haynes. 1996. In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expression. J. Immunol. 156:1557.
5. Nathan, C., and M. Sporn. 1991. Cytokines in context. J. Cell Biol. 113:981.
6. Noble, P. W., F. R. Lake, P. M. Henson, and D. W. H. Riches. 1993. Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-α-dependent mechanism in murine macrophages. J. Clin. Invest. 91:2368.
7. Gailit, J., and R. A. F. Clark. 1994. Wound repair in the context of extracellular matrix. Curr. Opin. Cell Biol. 6:717.
8. Savill, J. S., and C. Haslett. 1994. Fate of neutrophils. In Immunopharmacology of Neutrophils. P. G. Hellewell and T. J. Williams, eds. Academic Press, London, p. 295.
9. Weiss, S. J. 1989. Mechanisms of disease: tissue destruction by neutrophils. N. Engl. J. Med. 320:365.
10. Whyte, M. K. B., L. C. Meagher, J. MacDermot, and C. Haslett. 1993. Impairment of function in aging neutrophils is associated with apoptosis. J. Immunol. 150:5124.
11. Dransfield, I., S. C. Stocks, and C. Haslett. 1995. Regulation of cell adhesion molecule expression and function associated with neutrophil apoptosis. Blood 85:3264.
12. 2. J. Leukocyte Biol. 52:269.
13. Savill, J. S., V. A. Fadok, P. M. Henson, and C. Haslett. 1993. Phagocyte recognition of cells undergoing apoptosis. Immunol. Today 14:131.
14. Cox, G., J. Crossley, and Z. Xing. 1995. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of pulmonary inflammation in vivo. Am. J. Respir. Cell Mol. Biol. 12:232.
15. 3/CD36/thrombospondin recognition mechanism and lack of phlogistic response. Am. J. Pathol. 149:911.
16. Wright, S. D., L. S. Craigmyle, and S. C Silverstein. 1983. Fibronectin and serum amyloid P component stimulate C3b-and C3bi-mediated phagocytosis in cultured human monocytes. J. Exp. Med. 158:1338.
17. Brown, E. J. 1986. The role of extracellular matrix proteins in the control of phagocytosis. J. Leukocyte Biol. 39:579.
18. Newman, S. L., and M. A. Tucci. 1990. Regulation of human monocyte/macrophage function by extracellular matrix: adherence of monocytes to collagen matrices enhances phagocytosis of opsonized bacteria by activation of complement receptors and enhancement of Fc receptor function. J. Clin. Invest. 86:703.
19. Dougherty, G. J., D. L. Cooper, J. F. Memory, and R. K. Chiu. 1994. Ligand binding specificity of alternatively spliced CD44 isoforms. J. Biol. Chem. 269: 9074.
20. Droll, A., S. T Dougherty, R. K. Chiu, J. F. Dirks, W. H. McBride, D. L. Cooper, and G. J. Dougherty. 1995. Adhesive interactions between alternatively spliced CD44 isoforms. J. Biol. Chem. 270:11567.
21. Dransfield, I., C. Cabanas, J. Barrett, and N. Hogg. 1992. Interaction of leukocyte integrins with ligand is necessary but not sufficient for function. J. Cell Biol. 116:1527.
22. Ackerman, S. K., and S. D. Douglas. 1978. Purification of human monocytes on microexudate-coated surfaces. J. Immunol. 120:1372.
23. Partridge, L. J., and I. Dranstield. 1993. Isolation and characterization of mononuclear phagocytes. In Tumour Immunobiology: a Practical Approach. G. Gallagher, R. C. Rees, and C. W. Reynolds, eds. Oxford University Press, Oxford, p. 91.
24. Dransfield, I., A.-M. Buckle, J. S. Savill, A. McDowall, C. Haslett, and N. Hogg. 1994. Neutrophil apoptosis is associated with a reduction in CD16 (FcγRIII) expression. J. Immunol. 153:1254.
25. Savill, J. S., A. H. Wyllie, J. E. Henson, M. J. Walnort, P. M. Henson, and C. Haslett. 1989. Macrophage phagocytosis of aging neutrophils in inflammation: programmed cell death in the neutrophil leads to its recognition by macrophages. J. Clin. Invest. 83:865.
26. Pommier, C. G., S. Inada, L. F. Fries, T. Takahashi, M. M. Frank, and E. J. Brown. 1983. Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes. J. Exp. Med. 157:1844.
27. Newman, S. L., J. E. Henson, and P. M. Henson. 1982. Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J. Exp. Med. 156:430.
28. Fadok, V. A., D. R. Voelker, P. A. Campbell, J. J. Cohen, D. L. Bratton, and P. M. Henson. 1992. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:2207.
29. Liao, H., M. J. Telen, and B. F. Haynes. 1995. Modification by CD44 mAb of hyaluronan binding to CD44-transfected Jurkat T cells. In Leukocyte Typing V: White Cell Differentiation Antigens. S. F. Schlossmannm I., Boumsell, W. Gilks, J. M. Harlan, S. Shaw, R. Silverstein, T. Springer, T. F. Tedder, and R. F. Todd, eds. Oxford University Press, Oxford, p. 1735.
30. Bazil, V., and V. Horejsi. 1992. Shedding of the CD44 adhesion molecule from leukocytes induced by anti-CD44 monoclonal antibody simulating the effect of a natural receptor ligand. J. Immunol. 149:747.
31. Webb, D. S. A., Y. Shimizu, G. A. van Seventer, S. Shaw, and T. L. Gerrard. 1990. LFA-3, CD44, and CD45: physiologic triggers of human monocyte TNF and IL-1 release. Science 249:1295.
32. Ren, Y., and J. S. Savill. 1995. Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis. J. Immunol. 154:2366.
33. Pierres, A., C. Lipcey, C. Mawas, and D. Olive. 1992. A unique CD44 monoclonal antibody identifies a new T cell activation pathway. Eur. J Immunol. 22:413.
34. Lesley, J., P. W. Kincade, and K. Hyman. 1993. Antibody-induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody. Eur. J. Immunol. 23:1902.
35. Vermot-Desroches, C., J. Wijdenes, E. Valmu, C. Roy, R. Pigott, P. Nortamo, and C. J. Gahmberg. 1995. A CD44 monoclonal antibody differentially regulates CD11a/CD18 binding to intercellular adhesion molecules CD54, CD102 and CD50. Eur. J. Immunol. 25:2460.
36. Green, S. J., G. Tarone, and C. Underhill. 1988. Aggregation of macrophages and fibroblasts is inhibited by a monoclonal antibody to the hyaluronate receptor. Exp. Cell Res. 178:224.
37. Culty, M., K. Miyake, P. W. Kincade, E. Silorski, E. C. Butcher, and C. Underhill. 1990. The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins. J. Cell Biol. 111:2765.
38. Underhill, C. 1992. CD44: the hyaluronan receptor. J. Cell Sci. 103:293.
39. Haegel, H., C. Tolg, M. Hofmann, and R. Ceredig. 1993. Activated mouse astrocytes and T cells express similar CD44 variants: role of CD44 in astrocyte/T cell binding. J. Cell Biol. 122:1067.
40. DeGrendele, H. C., P. Estess, E. J. Picker, and M. H. Siegelman. 1996 CD44 and ils ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway. J. Exp. Med. 183:1119.
41. Koopman, G., Y. van Kooyk, M. de Graaf, G. J. L. M. Meyer, C. G. Figdor, and S. T. Pals. 1990. Triggering of the CD44 antigen on T lymphocytes promotes T cell adhesion through the LFA-1 pathway. J. Immunol. 145:3589.
42. Bruynzeel, I., G. Koopman, L. M. H. van der Raaij, S. T. Pals, and R. Willemze. 1993. CD44 antibody stimulates adhesion of peripheral blood T cells to keratinocytes through the leukocyte function-associated antigen-1/intercellular adhesion molecule-1 pathway. J. Invest. Dermatol. 100:424.
43. Riches, D. W. H., J. Y. Channon, C. C. Leslie, and P. M. Henson. 1988. Receptor-mediated signal transduction in mononuclear phagocytes. Prog. Allergy 42:65.
44. + T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections. J. Exp. Med. 180:1943.
45. Fadok, V. A., J. S. Savill, C. Haslett, D. L. Bratton, D. Doherty, P. A. Campbell, and P. M. Henson. 1992. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells. J. Immunol. 149:4029.
46. Hart, S P., C. Haslett, and I. Dransfield 1996. Recognition of apoptotic cells by phagocytes. Experientia 52:950.
47. Taher, T. E. I., L. Smit, A. W. Griffioen, E. J. M. Schilder-Tol, J. Borst, and S. T. Pals. 1996 Signaling through CD44 is mediated by tyrosine kinases. J. Biol. Chem. 271:2863.
48. Rothman, B. L., N. Kennure, K. A. Kelley, M. Katz, and T. M. Aune. 1993. Elevation of intracellular cAMP in human T lymphocytes by an anti-CD44 mAb. J. Immunol. 151:6016.
49. Camp, R. L., T. A. Kraus, and E. Pure. 1991. Variations in the cytoskeletal interaction and posttranslational modification of the CD44 homing receptor in macrophages. J. Cell Biol. 115:1281.
50. Tsukita, S., K. Oishi, N. Sato, J. Sagara, A. Kawai, and S. Tsukita. 1994. ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J. Cell Biol. 126:191.
51. Isacke, C. M. 1994. The role of the cytoplasmic domain in regulating CD44 function. J. Cell Sci. 107:2153.