Antitumor agents. 177. Design, syntheses, and biological evaluation of novel etoposide analogs bearing pyrrolecarboxamidino group as DNA topoisomerase II inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 5, 1997, Pages 607-612

  Ji, Zheng ^a   Wang, Hui Kang ^a   Bastow, Kenneth F ^a   Zhu, Xiao Kang ^a   Cho, Sung Jin ^a   Cheng, Yung Chi ^b   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4' O DEMETHYL 4BETA [N (1''' METHYL 4''' NITROPYRROL 2''' CARBONYL) 4'' AMINOANILINO] 4 DEOXYPODOPHYLLOTOXIN; ANTINEOPLASTIC AGENT; ETOPOSIDE; GYRASE INHIBITOR; PODOPHYLLOTOXIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; TUMOR CELL LINE;

EID: 0031552141     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00060-7     Document Type: Article

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