Antitumor agents. 164. Podophenazine, 2″,3″-dichloropodophenazine, benzopodophenazine, and their 4β-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors

Journal of Medicinal Chemistry

Volumn 39, Issue 7, 1996, Pages 1396-1402

  Cho, Sung Jin ^a   Kashiwada, Yoshiki ^a   Bastow, Kenneth F ^a   Cheng, Yung Chi ^b   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2'',3'' DICHLORO 4 DEOXY 4BETA (4 NITROANILINO) 4' NORPODOPHENAZINE; 2'',3'' DICHLOROPODOPHENAZINE; 4 DEOXY 4BETA (4 NITROANILINO) 4' NORPODOPHENAZINE; ANTINEOPLASTIC AGENT; BENZOPODOPHENAZINE; ETOPOSIDE; GYRASE INHIBITOR; PODOPHENAZINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; DOSE RESPONSE; DRUG CONFORMATION; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; NASOPHARYNX CANCER; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL DIVISION; DNA; DNA TOPOISOMERASES, TYPE II; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; ETOPOSIDE; HUMANS; KB CELLS; MOLECULAR STRUCTURE; PHENAZINES; PODOPHYLLOTOXIN;

EID: 0000734820     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950548u     Document Type: Article

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