Long non-stop reading frames on the antisense strand of heat shock protein 70 genes and prion protein (PrP) genes are conserved between species

Biological Chemistry

Volumn 378, Issue 12, 1997, Pages 1521-1530

  Rother, Kristina I ^a   Clay, Oliver K ^a   Bourquin, Jean Pierre ^a   Silke, John ^a   Schaffner, Walter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Antisense non stop reading frames; Antisense open reading frame; Heat shock cognate; Heat shock elements; Prion protein; Transmissible spongiform encephalopathies TSE

Indexed keywords

COMPLEMENTARY DNA; COMPLEMENTARY RNA; HEAT SHOCK PROTEIN 70; LEUCINE; PRION PROTEIN; SERINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CODON; GENE STRUCTURE; HUMAN; HUMAN CELL; INTRON; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; STOP CODON;

ANIMALIA; AVES; EUTHERIA; MAMMALIA; METATHERIA; VERTEBRATA;

EID: 0031468829     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/bchm.1997.378.12.1521     Document Type: Article

References (63)

1. Aguzzi, A., and Weissmann, C. (1997). Prion research: The next frontiers. Nature 389, 795-798.
2. Atanasoski, S., Toldo, S.S., Malipiero, U., Schreiber, E., Fries, R., and Fontana, A. (1995). Isolation of the human genomic brain-2/N-Oct 3 gene (POUF3) and assignment to chromosome 6q16. Genomics. 26, 272-280.
3. Bass, B.L., and Weintraub, H. (1988). An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell 55, 1089-1098.
4. Benne, R. (1996). RNA editing: how a message is changed. Curr. Opin. Genet. Dev. 6, 221-231.
5. Berry, M.J., Banu, L., Harney, J.W., and Larsen, P.R. (1993). Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons. EMBO J. 12, 3315-3322.
6. Boldogköi, Z., Murvai, J., and Fodor, I. (1995). G and C accumulation at silent positions of codons produces additional NRFs. Trends Genet. 11, 125-126.
7. Bost, K.L., Smith, E.M., and Blalock, J.E. (1985). Similarity between the corticotropin (ACTH) receptor and a peptide encoded by an RNA that is complementary to ACTH mRNA. Proc. Natl. Acad. Sci. USA 82, 1372-1375.
8. Brentani, R.R., Ribeiro, S.F., Potocnjak, P., Pasqualini, R., Lopes, J.D., and Nakaie, C. (1988). Characterization of the cellular receptor for fibronectin through a hydropathic complementary approach. Proc. Natl. Acad. Sci. USA. 85, 364-367.
9. Brunak, S., Engelbrecht, J., and Knudsen, S. (1991). Prediction of human mRNA donor and acceptor sites from the DNA sequence. J. Mol. Biol. 220, 49-65.
10. Büeler, H., Fischer, M., Lang, Y., Bluethmann, H., Lipp, H.P., DeArmond, S.J., Prusiner, S.B., Aguet, M., and Weissmann, C. (1992). Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature. 356, 577-582.
11. Büeler, H., Aguzzi, A., Sailer, A., Greiner, R.A., Autenried, P., Aguet, M., and Weissmann, C. (1993). Mice devoid of PrP are resistant to scrapie. Cell 73, 1339-1347.
12. Chernoff, Y.O., Lindquist, S.L., Ono, B., Inge-Vechtomov, S.G., and Liebamn, S.W (1995). Role of the Chaperone Protein Hsp104 in Propagation of the yeast Prion-like Factor [psi+]. Science. 268, 880-884.
13. + currents. Neurosci. Lett. 209, 49-52.
14. Collinge, J., Whittington, M.A., Sidle, K.C., Smith, C.J., Palmer, M.S., Clarke, A.R., and Jefferys, J.G. (1994). Prion protein is necessary for normal synaptic function. Nature. 370, 295-297.
15. Devereux, J., Haeberli, P., and Smithies, O. (1984). A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12, 387-395.
16. Elton, T.S., Dion, L.D., Bost, K.L., Oparil, S., and Blalock, J.E. (1988). Purification of an angiotensin II binding protein by using antibodies to a k-peptide encoded by angiotensin II complementary RNA. Proc. Natl. Acad. Sci. USA 85, 2518-2522.
17. Fasman, K.H., Letovsky, S.I., Cottingham, R.W., and Kingsbury, D.T. (1997). The GDB(TM) Human Genome Database Anno 1997. Nucleic Acids Res. 25, 72-80.
18. Felsenstein, K.M., and Goff, S.P. (1992). Mutational analysis of the gag-pol junction of Moloney murine leukemia virus: requirements for expression of the gag-pol fusion protein. J. Virol. 66, 6601-6608.
19. Feng, Y.X., Copeland, T.D., Oroszlan, S., Rein, A., and Levin, J.G. (1990). Identification of amino acids inserted during suppression of UAA and UGA termination codons at the gag-pol junction of Moloney murine leukemia virus. Proc. Natl. Acad. Sci. USA 87, 8860-8863.
20. Fischer, M., Rulicke, T., Raeber, A., Sailer, A., Moser, M., Oesch, B., Brandner, S., Aguzzi, A., Weissmann, C. (1996). Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15, 1255-1264.
21. Forsdyke, D.R. (1995). Sense in Antisense. J. Mol. Evol. 41, 582-586.
22. Goldgaber, D. (1991). Anticipating the anti-prion protein. Nature. 351, 106.
23. Günther, E., and Walter, L. (1994). Genetic aspects of the Hsp70 multigene family in vertebrates. Experientia. 50, 987-1001.
24. Harris, D.A., Falls, D.L., Johnson, F.A., and Fischbach, G.D. (1991). A prion-like protein from chicken brain copurifies with an acetylcholin receptor-inducing activity. Proc. Natl. Acad. Sci. USA 88, 7664-7668.
25. Herms, J.W., Kretzchmar, H.A., Titz, S., and Keller, B.U. (1995). Patch-clamp analysis of synaptic transmission to cerebellar purkinje cells of prion protein knockout mice. Eur. J. Neurosci. 7, 2508-2512.
26. Hewinson, R.G., Lowings, J.P., Dawson, M.D., and Woodward, M.J. (1991). In: Anti-prions and other agents (Scientific Correspondence). Nature 352, 291.
27. Hunt, C., and Morimoto, R.I. (1985). Conserved features of eukaryotic Hsp70 genes revealed by comparison with the nucleotide sequence of human Hsp70. Proc. Natl. Acad. Sci. USA 82, 6455-6459.
28. Kast, P. (1994). A second-generation general purpose cloning vector for efficient positive selection of recombinant clones. Gene 138, 109-114.
29. Kirkwood, J.K., and Cunningham, A.A. (1994). Epidemiological observations on spongiform encephalopathies in captive wild animals in the British Isles. Vet. Rec. 135, 296-303.
30. Konstantopoulou, I., Ouzounis, C.A., Drosopoulou, E., Yiangou, M., Sideras, P., Sander, C., Scouras, Z.G. (1995). A Drosophila hsp70 gene contains long, antiparallel, coupled open reading frames (LAC ORFs) conserved in homologous loci. J. Mol. Evol. 41, 414-420.
31. LéJohn, H.B., Cameron, L.E., Yang, B., and Rennie, S.L. (1994). Molecular characterization of an NAD-specific Glutamate Dehydrogenase Gene Inducible by L-Glutamine. J. Biol. Chem. 269, 4523-4531.
32. Liautard, J.-P. (1991). Are prions misfolded molecular chaperones? FEBS Letters 294, 155-157.
33. Lipman, D.J. (1997). Making (anti)sense of non-coding sequence conservation. Nucleic Acids Res. 25, 3580-3583.
34. Lledo, P.M., Tremblay, P., DeArmond, S.J., Prusiner, S.B., and Nicoll, R.A. (1996). Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus. Proc. Natl. Acad. Sci. USA 93, 2403-2407.
35. Low, S.C., and Berry, M.J. (1996). Knowing when not to stop: selenocysteine incorporation in eukaryotes. Trends Biochem Sci. 21, 203-208.
36. Maquat, L..E. (1995). When cells stop making sense: effect of nonsense codons on RNA metabolism in vertebrate cells. RNA 1, 453-465
37. Marck, C. (1988). "DNA Strider": a "C" program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers. Nucleic Acids Res. 16, 1829-1836.
38. Merino, E., Balbas, P., Puente, J., and Bolivar, F. (1994). Antisense overlapping reading frames in genes from bacteria to humans. Nucleic Acids Res. 22, 1903-1908.
39. Morimoto, R.I., Tissihres, A., and Georgopoulos, C. (1994). The biology of heat shock proteins and molecular chaperones (Plainview, New York: Cold Spring Harbor Laboratory Press).
40. Moser, M., Oesch, B., and Büeler, H. (1993). An anti-prion protein? Nature 362, 213-214.
41. Murashov, A.K., and Wolgemuth, D.J. (1996). Sense and antisense transcripts of the developmentally regulated murine Hsp70.2 gene are expressed in distinct and only partially overlapping areas in the adult brain. Brain Res. Mol. Brain Res. 37, 85-95.
42. Nakamura, Y., Gojobori, T., Ikemura, T. (1997). Codon usage tabulated from the international DNA sequence databases. Nucleic Acids Res. 25, 244-245.
43. Osawa, S. (1995). Evolution of the Genetic Code (Oxford, etc.: Oxford University Press).
44. Pearson, W.R., and Lipman, D.J. (1988). Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85, 2444-2448.
45. Peltz, S.W., Brown, A.M., and Jacobson, A. (1993). mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor. Genes Dev. 7, 1737-1754.
46. Perkins L.A., Doctor, J.S., Zhang, K., Stinson, L., Perrimon, N., and Craig, E.A. (1990). Molecular and developmental characterisation of the heat shock cognate 4 gene of Drosophila melanogaster. Mol. Cell. Biol. 10, 3232-3238.
47. Pocchiari, M. (1994). Prions and related neurological diseases. Mol. Aspects Med. 15, 195-291.
48. Prusiner, S.B. (1997). Prion diseases and the BSE crisis. Science 278, 245-251.
49. Schätzl, H.M., Da Costa, M., Taylor, L., Cohen, F.E., and Prusiner, S.B. (1995). Prion protein variation among primates. J. Mol. Biol. 245, 362-374.
50. Schreiber, E., Tobler, A., Malipiero, U., Schaffner, W., and Fontana, A. (1993). cDNA cloning of human N-Oct3, a nervous-system specific POU domain transcription factor binding to the octamer DNA motif. Nucleic Acids Res. 21, 253-258.
51. Silke, J. (1997). The majority of long non stop reading frames on the antisense strand can be explained by biased codon usage. Gene 194, 143-155.
52. Stefani, R.M.P., and Gomes, S.L. (1995). A unique intron containing Hsp70 gene induced by heat shock and during sporulation in the aquatic fungus Blastocladiella emersoni. Gene. 152, 19-26.
53. Tamura, Y., Peng, P., Liu, K., Daou, M., and Srivastava, P.K. (1997). Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations. Science 278, 117-120.
54. Tatzelt, J., Zuo, J., Voellmy, R., Scott, M., Hartl, U., Prusiner, S.B., and Welch, W.J. (1995). Scrapie prions selectively modify the stress response in neuroblastoma cells. Proc. Natl. Acad. Sci. USA 92, 2944-2948.
55. Taylor, E.W. (1995). Selenium and cellular immunity. Biol. Trace Elem. Res. 49, 85-95.
56. Telling, G.G., Scott, M., Mastrianni, J., Gabizon, R., Torchia, M., Cohen, F.E., DeArmond, S.J., and Prusiner, S.B. (1995). Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83, 79-90.
57. Tobler, I., Deboer, T., and Fischer, M. (1997). Sleep and sleep regulation in normal and prion protein-deficient mice. J. Neurosci. 17, 1869-1879.
58. Tuite, M.F., and Lindquist, S.L. (1996). Maintenance and inheritance of yeast prions. Trends Genet. 12, 467-471.
59. Uberbacher, E.C., and Mural, R.J. (1991). Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach. Proc. Natl. Acad. Sci. USA 88, 11261-11265.
60. Volk, R., Köster, M., Pöting, A., Hartmann, L., and Knöchel, W. (1989). An antisense transcript from the Xenopus laevis bFGF gene coding for an evolutionary conserved 24 kd protein. EMBO J. 8, 2983-2988.
61. Windl, O., Dempster, M., Estibeiro, P., and Lathe, R. (1995). A candidate marsupial PrP gene reveals two domains conserved in mammalian PrP proteins. Gene 159, 181-186.
62. Yomo, T., and Urabe, I. (1994). A frame-specific symmetry of complementary strands of DNA suggest the existence of genes on the antisense strand. J. Mol. Evol. 38, 113-120.
63. Yost, H.J., Petersen, R.B., and Lindquist, S. (1990). RNA metabolism: Strategies for regulation in the heat shock response. Trends Genet. 6, 223-227.