-
1
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
Stein CA, Cheng YC. Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science 1993; 261: 1004.
-
(1993)
Science
, vol.261
, pp. 1004
-
-
Stein, C.A.1
Cheng, Y.C.2
-
2
-
-
0023057552
-
The use of single-stranded DNA and RNase H to promote quantitative "hybrid arrest of translation" of mRNA/DNA hybrids in reticulocyte lysate cell-free translations
-
Minshull J, Hunt T. The use of single-stranded DNA and RNase H to promote quantitative "hybrid arrest of translation" of mRNA/DNA hybrids in reticulocyte lysate cell-free translations. Nucleic Acids Research 1986; 14: 6433-51.
-
(1986)
Nucleic Acids Research
, vol.14
, pp. 6433-6451
-
-
Minshull, J.1
Hunt, T.2
-
3
-
-
0028025205
-
Selection of antisense oligonucleotides on the basis of genomic frequency of the target sequence
-
Han J, Zhu Z, Hsu C, Finley, W. Selection of antisense oligonucleotides on the basis of genomic frequency of the target sequence. Antisense Research and Development 1994; 4: 53-65.
-
(1994)
Antisense Research and Development
, vol.4
, pp. 53-65
-
-
Han, J.1
Zhu, Z.2
Hsu, C.3
Finley, W.4
-
4
-
-
11944267365
-
Antisense oligonucleotides: A new therapeutic principle
-
Uhlmann E, Peymann A. Antisense oligonucleotides: a new therapeutic principle. Chemical Reviews 1990; 90: 543-544.
-
(1990)
Chemical Reviews
, vol.90
, pp. 543-544
-
-
Uhlmann, E.1
Peymann, A.2
-
5
-
-
0024283331
-
Phosphoramidate analogues of DNA: Synthesis and thermal stability of hetroduplexes
-
Froehler B, Ng P, Matteucci M. Phosphoramidate analogues of DNA: Synthesis and thermal stability of hetroduplexes. Nucleic Acid Research 1988; 16: 4831-4839.
-
(1988)
Nucleic Acid Research
, vol.16
, pp. 4831-4839
-
-
Froehler, B.1
Ng, P.2
Matteucci, M.3
-
6
-
-
0024326585
-
RNase H cleavage of RNA hybridised to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds
-
Furdon PJ, Dominski Z, Kole R. RNase H cleavage of RNA hybridised to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds. Nucleic Acid Research 1989; 17: 9193-9204.
-
(1989)
Nucleic Acid Research
, vol.17
, pp. 9193-9204
-
-
Furdon, P.J.1
Dominski, Z.2
Kole, R.3
-
7
-
-
0023755696
-
Oligonucleotide phosphoramidates and phosphorothioates as inhibitors of the immunodeficiency virus
-
Agrawal S, Goodchild J, Civera MP, Thornton AH, Sarin PS, Zamecnik PC. Oligonucleotide phosphoramidates and phosphorothioates as inhibitors of the immunodeficiency virus. Proceedings of the National Academy of Science USA 1988; 85: 7079-7083
-
(1988)
Proceedings of the National Academy of Science USA
, vol.85
, pp. 7079-7083
-
-
Agrawal, S.1
Goodchild, J.2
Civera, M.P.3
Thornton, A.H.4
Sarin, P.S.5
Zamecnik, P.C.6
-
8
-
-
0025346998
-
Oligodeoxynucleotides phosphorothioate stability in subcellular extracts, culture media, sera, and cerebrospinal fluid
-
Campbell JM, Bacon TA, Wickstrom E. Oligodeoxynucleotides phosphorothioate stability in subcellular extracts, culture media, sera, and cerebrospinal fluid. Journal of Biochemical and Biophysical Methods 1990; 20: 259-267.
-
(1990)
Journal of Biochemical and Biophysical Methods
, vol.20
, pp. 259-267
-
-
Campbell, J.M.1
Bacon, T.A.2
Wickstrom, E.3
-
11
-
-
0029588560
-
Antisense phosphorothioate oligodeoxynucleotides - Introductory concepts and possible molecular mechanisms of toxicity
-
Zon G. Antisense phosphorothioate oligodeoxynucleotides - introductory concepts and possible molecular mechanisms of toxicity. Toxicology Letters 1995; 82-3: 419-424.
-
(1995)
Toxicology Letters
, vol.82
, Issue.3
, pp. 419-424
-
-
Zon, G.1
-
12
-
-
17144436717
-
Pharmacology and toxicology of phosphorothioate oligonucleotides in the mouse, rat, monkey and man
-
Iversen PL, Copple BL, Tewary HK. Pharmacology and toxicology of phosphorothioate oligonucleotides in the mouse, rat, monkey and man. Toxicology Letters 1995; 82-3: 425-430.
-
(1995)
Toxicology Letters
, vol.82
, Issue.3
, pp. 425-430
-
-
Iversen, P.L.1
Copple, B.L.2
Tewary, H.K.3
-
14
-
-
0029873193
-
Antitumour effect of c-myc antisense phosphorothioate oligonucleotides on human melanoma cells in vitro and in mice
-
Leonetti C, D'Agnano I, Lozupone F, Valentini, A, Geiser T, Zon G, Calbretta B, Citro G, Zupi G. Antitumour effect of c-myc antisense phosphorothioate oligonucleotides on human melanoma cells in vitro and in mice. Journal of the National Cancer Institute 1996; 88: 419-429
-
(1996)
Journal of the National Cancer Institute
, vol.88
, pp. 419-429
-
-
Leonetti, C.1
D'Agnano, I.2
Lozupone, F.3
Valentini, A.4
Geiser, T.5
Zon, G.6
Calbretta, B.7
Citro, G.8
Zupi, G.9
-
15
-
-
0028924169
-
Sequence context of antisense RelA/NK-kB phosphorothioates determines specificity
-
Maltese JY, Sharma HW, Vassilev L, Narayanan R. Sequence context of antisense RelA/NK-kB phosphorothioates determines specificity. Nucleic Acids Research 1995; 23: 1146-1151.
-
(1995)
Nucleic Acids Research
, vol.23
, pp. 1146-1151
-
-
Maltese, J.Y.1
Sharma, H.W.2
Vassilev, L.3
Narayanan, R.4
-
16
-
-
0028087886
-
Ability of oligonucleotides with certain palindromes to nduce interferon production and augment natural killer cell activity is associated with their base length
-
Tamamoto T, Yamamoto S, Kataoka T, Tokunaga T. Ability of oligonucleotides with certain palindromes to nduce interferon production and augment natural killer cell activity is associated with their base length. Antisense Research and Development 1994; 4: 119-122.
-
(1994)
Antisense Research and Development
, vol.4
, pp. 119-122
-
-
Tamamoto, T.1
Yamamoto, S.2
Kataoka, T.3
Tokunaga, T.4
-
19
-
-
0029127845
-
Pharmacokinetics of an anti-human immunodeficiency virus antisense oligonucleotide phosphorothioate (GEM 91) in HIV-infected subjects
-
Zhang RW, Yan JM, Shahinian H, Amin G, Lu ZH, Liu TP, Saag MS, Jiang ZW, Temsamani J, Martin RR, Schechter PJ, Agrawal S, Diasio RB. Pharmacokinetics of an anti-human immunodeficiency virus antisense oligonucleotide phosphorothioate (GEM 91) in HIV-infected subjects. Clinical Pharmacology and Therapeutics 1995; 58: 44-53.
-
(1995)
Clinical Pharmacology and Therapeutics
, vol.58
, pp. 44-53
-
-
Zhang, R.W.1
Yan, J.M.2
Shahinian, H.3
Amin, G.4
Lu, Z.H.5
Liu, T.P.6
Saag, M.S.7
Jiang, Z.W.8
Temsamani, J.9
Martin, R.R.10
Schechter, P.J.11
Agrawal, S.12
Diasio, R.B.13
-
20
-
-
15444342085
-
An open-label multidose safety, pharmacokinetic and preliminary antiviral activity study of GEM 91 administered by intermittent intravenous infusion in HIV-positive adults
-
San Francisco, Abs 1
-
Serini D, Katlama C, Vilde JL et al. An open-label multidose safety, pharmacokinetic and preliminary antiviral activity study of GEM 91 administered by intermittent intravenous infusion in HIV-positive adults 35th International Conference on Antimicrobial Agents and Chemotherapy, San Francisco, 1996, Abs 1.
-
(1996)
35th International Conference on Antimicrobial Agents and Chemotherapy
-
-
Serini, D.1
Katlama, C.2
Vilde, J.L.3
-
22
-
-
0029743490
-
Progress in the development of antisense drugs
-
Crooke ST. Progress in the development of antisense drugs. Expert Opinions in Investigative Drugs 1996; 5: 1047-1052.
-
(1996)
Expert Opinions in Investigative Drugs
, vol.5
, pp. 1047-1052
-
-
Crooke, S.T.1
-
25
-
-
0029934723
-
Evaluation of c-fas oncogene product (p21) in superficial bladder cancer
-
Fontana D, Bellma M, Scoffone C, Cagnazzi E, Cappia S, Cavallo F, Russo R, Leonardo E. Evaluation of c-fas oncogene product (p21) in superficial bladder cancer. European Urology 1996; 29: 470-476.
-
(1996)
European Urology
, vol.29
, pp. 470-476
-
-
Fontana, D.1
Bellma, M.2
Scoffone, C.3
Cagnazzi, E.4
Cappia, S.5
Cavallo, F.6
Russo, R.7
Leonardo, E.8
-
27
-
-
9244223546
-
Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies
-
Bishop R, Iversen PL, Bayeve E, Sharp JG, Greiner TC, Copple BL, Ruddon R, Zon G, Spinolo J, Arneson M, Armitage JO, Kessinger A. Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies. Journal of Clinical Oncology 1996; 14: 1320-1326.
-
(1996)
Journal of Clinical Oncology
, vol.14
, pp. 1320-1326
-
-
Bishop, R.1
Iversen, P.L.2
Bayeve, E.3
Sharp, J.G.4
Greiner, T.C.5
Copple, B.L.6
Ruddon, R.7
Zon, G.8
Spinolo, J.9
Arneson, M.10
Armitage, J.O.11
Kessinger, A.12
-
28
-
-
0027983025
-
Combinationally selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion
-
Wyatt JR, Vickers TA, Robertson JL, Buckheit RW, Klimkait T et al. Combinationally selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proceedings of the National Academy of Science USA 1994; 95: 1356-1360.
-
(1994)
Proceedings of the National Academy of Science USA
, vol.95
, pp. 1356-1360
-
-
Wyatt, J.R.1
Vickers, T.A.2
Robertson, J.L.3
Buckheit, R.W.4
Klimkait, T.5
-
29
-
-
0028061392
-
Characterisation of the oligonucleotide mediated inhibition of interferon g-receptor major histocompatibility complex class I and intracellular adhesion molecule-1
-
Ramanathan M, Lantz M, MacGregor RD, Garovoy MR, Hunt CA. Characterisation of the oligonucleotide mediated inhibition of interferon g-receptor major histocompatibility complex class I and intracellular adhesion molecule-1. Journal of Biological Chemistry 1994; 269: 24564-24574.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 24564-24574
-
-
Ramanathan, M.1
Lantz, M.2
MacGregor, R.D.3
Garovoy, M.R.4
Hunt, C.A.5
-
31
-
-
0026736764
-
Inhibition of cell adhesion to plastic substratum by phosphorothioate oligonucleotide
-
Watson PH, Pon RT, Shiu RPC. Inhibition of cell adhesion to plastic substratum by phosphorothioate oligonucleotide. Experimental Cell Research 1992; 202: 391-397.
-
(1992)
Experimental Cell Research
, vol.202
, pp. 391-397
-
-
Watson, P.H.1
Pon, R.T.2
Shiu, R.P.C.3
-
32
-
-
0027319530
-
Effects of sequence of thioated oligonucleotides on cultured human mammary epithelial cells
-
Yaswen P, Stampler MR, Ghosh K, Cohen JS. Effects of sequence of thioated oligonucleotides on cultured human mammary epithelial cells. Antisense Research 1993; 3: 67-77.
-
(1993)
Antisense Research
, vol.3
, pp. 67-77
-
-
Yaswen, P.1
Stampler, M.R.2
Ghosh, K.3
Cohen, J.S.4
-
33
-
-
0029001621
-
The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism
-
Burgess TL, Fisher EF, Ross SL, Bready JV, Qian YX, Bayewitch LA, Cohen AM, Herrera CJ, Hu SSF, Kramer TB et al. The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proceedings of the National Academy of Science USA 1995; 92: 4051-4055.
-
(1995)
Proceedings of the National Academy of Science USA
, vol.92
, pp. 4051-4055
-
-
Burgess, T.L.1
Fisher, E.F.2
Ross, S.L.3
Bready, J.V.4
Qian, Y.X.5
Bayewitch, L.A.6
Cohen, A.M.7
Herrera, C.J.8
Hu, S.S.F.9
Kramer, T.B.10
-
34
-
-
0028806487
-
Does antisense exist?
-
Stein CY. Does antisense exist? Nature Medicine 1995; 11: 1119-1121.
-
(1995)
Nature Medicine
, vol.11
, pp. 1119-1121
-
-
Stein, C.Y.1
-
35
-
-
0029943679
-
Phosphorothioate antisense oligonucleotides: Questions of specificity
-
Stein CY. Phosphorothioate antisense oligonucleotides: questions of specificity. Trends in Biotechnology 1996; 14: 147-148.
-
(1996)
Trends in Biotechnology
, vol.14
, pp. 147-148
-
-
Stein, C.Y.1
-
36
-
-
0028908671
-
Competitive triplex/quadruplex equilibria involving guanine rich oligonucleotides
-
Olivas WM, Mather LJ. Competitive triplex/quadruplex equilibria involving guanine rich oligonucleotides. Biochemistry 1995; 34: 278-284.
-
(1995)
Biochemistry
, vol.34
, pp. 278-284
-
-
Olivas, W.M.1
Mather, L.J.2
-
37
-
-
0030271959
-
Antisense oligonucleotides: Towards clinical trials
-
Agrawal S. Antisense oligonucleotides: Towards clinical trials. Trends in Biotechnology 1996; 14: 376-386.
-
(1996)
Trends in Biotechnology
, vol.14
, pp. 376-386
-
-
Agrawal, S.1
-
38
-
-
0030909609
-
Mixed-backbone oligonucleotides as second generation antisense oligonucleotides - In vitro and in vivo studies
-
Agrawal S, Jaing ZW, Zhao QY, Shaw D, Cai QY, Roskey A, Channavajjala L, Saxinger C, Zhang RW. Mixed-backbone oligonucleotides as second generation antisense oligonucleotides - in vitro and in vivo studies. Proceedings of the National Academy of Sciences USA 1997; 94: 2620-2625.
-
(1997)
Proceedings of the National Academy of Sciences USA
, vol.94
, pp. 2620-2625
-
-
Agrawal, S.1
Jaing, Z.W.2
Zhao, Q.Y.3
Shaw, D.4
Cai, Q.Y.5
Roskey, A.6
Channavajjala, L.7
Saxinger, C.8
Zhang, R.W.9
-
39
-
-
18844455464
-
Second generation antisense oligonucleotides: From nuclease resistance to biological efficacy in animals
-
Altmann KH, Dean N, Fabbro D, Frierer SM, Geiger T, Härter R et al. Second generation antisense oligonucleotides: From nuclease resistance to biological efficacy in animals. Chimia 1996; 50: 168-176.
-
(1996)
Chimia
, vol.50
, pp. 168-176
-
-
Altmann, K.H.1
Dean, N.2
Fabbro, D.3
Frierer, S.M.4
Geiger, T.5
Härter, R.6
-
41
-
-
0026575221
-
Selection of single stranded DNA molecules that bind and inhibit human thrombin
-
Bock LC, Griffin LC, Latham, JA, Vermaas EH, Toole JJ. Selection of single stranded DNA molecules that bind and inhibit human thrombin. Nature 1992; 355: 564-566.
-
(1992)
Nature
, vol.355
, pp. 564-566
-
-
Bock, L.C.1
Griffin, L.C.2
Latham, J.A.3
Vermaas, E.H.4
Toole, J.J.5
-
42
-
-
0028340194
-
Sequence independent induction of the Spl transcription factor activity by phosphorothioate oligodeoxynucleotides
-
Perez JR, Li Y, Stein CA, Majumder S, Van Ooschot, Narayanan, R. Sequence independent induction of the Spl transcription factor activity by phosphorothioate oligodeoxynucleotides. Proceedings of the National Academy of Science USA 1994; 91: 5957-5961.
-
(1994)
Proceedings of the National Academy of Science USA
, vol.91
, pp. 5957-5961
-
-
Perez, J.R.1
Li, Y.2
Stein, C.A.3
Majumder, S.4
Van Ooschot5
Narayanan, R.6
-
43
-
-
0026573769
-
Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology
-
Gao W-Y, Hans F-S, Storm C, Egan W, Cheng Y-C. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology. Molecular Pharmacology 1992; 41: 223-229.
-
(1992)
Molecular Pharmacology
, vol.41
, pp. 223-229
-
-
Gao, W.-Y.1
Hans, F.-S.2
Storm, C.3
Egan, W.4
Cheng, Y.-C.5
-
45
-
-
0026310571
-
Non-sequence-specific inhibition of transterrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides
-
Ho PTC, Ishiguro K, Wickstrim E, Sartorelli AC. Non-sequence-specific inhibition of transterrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides. Antisense Research and Development 1991; 1: 329-342.
-
(1991)
Antisense Research and Development
, vol.1
, pp. 329-342
-
-
Ho, P.T.C.1
Ishiguro, K.2
Wickstrim, E.3
Sartorelli, A.C.4
-
46
-
-
0029564634
-
Non-sequence-specific inhibition of bacterial luminescence by phosphorothioate oligodeoxyribonucleotides
-
Chrisey LA, Pazirandeh M, Liss HS. Non-sequence-specific inhibition of bacterial luminescence by phosphorothioate oligodeoxyribonucleotides. Antisense Research and Development 1995; 5: 261-9.
-
(1995)
Antisense Research and Development
, vol.5
, pp. 261-269
-
-
Chrisey, L.A.1
Pazirandeh, M.2
Liss, H.S.3
-
47
-
-
0030961682
-
Sequence-independent effects of phosphorothioated on synaptic transmission and excitability in the hippocampus in vivo
-
Abraham WC, Logan B, Thompason VL, Williams JM, Tate WP. Sequence-independent effects of phosphorothioated on synaptic transmission and excitability in the hippocampus in vivo. Neuropharmacology 1997; 36: 345-352.
-
(1997)
Neuropharmacology
, vol.36
, pp. 345-352
-
-
Abraham, W.C.1
Logan, B.2
Thompason, V.L.3
Williams, J.M.4
Tate, W.P.5
-
48
-
-
0027178663
-
Oligonucleotides interact with recombinant CD4 at multiple sites
-
Yakubov L, Khaled Z, Zhang LM, Truneh A, Vlassov V, Stein CA. Oligonucleotides interact with recombinant CD4 at multiple sites. Journal of Biological, Chemistry 1993; 268: 18818-18823.
-
(1993)
Journal of Biological, Chemistry
, vol.268
, pp. 18818-18823
-
-
Yakubov, L.1
Khaled, Z.2
Zhang, L.M.3
Truneh, A.4
Vlassov, V.5
Stein, C.A.6
-
49
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors and remove it from low affinity binding sites on extracellular matrix
-
Guvakova MA, Yakubov LA, Vlodavsky J, Tonkinson JL, Stein CA. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors and remove it from low affinity binding sites on extracellular matrix. Journal of Biological Chemistry. 1995; 270: 2620-2627.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, J.3
Tonkinson, J.L.4
Stein, C.A.5
|