Sequence-independent effects of phosphorothioated oligonucleotides on synaptic transmission and excitability in the hippocampus in vivo

Neuropharmacology

Volumn 36, Issue 3, 1997, Pages 345-352

  Abraham, W C ^a   Logan, B ^a   Thompson, V L ^a   Williams, J M ^a   Tate, W P ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

antisense; dentate gyrus; epilepsy; hippocampus; long term potentiation (LTP); oligonucleotides; seizures; synaptic depression

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; PENTOBARBITAL; PHOSPHOROTHIOIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DRUG DISTRIBUTION; ELECTRIC POTENTIAL; ELECTROENCEPHALOGRAM; EPILEPTIC DISCHARGE; GENE EXPRESSION; HIPPOCAMPUS; IMMEDIATE EARLY GENE; INTRACEREBRAL DRUG ADMINISTRATION; LONG TERM POTENTIATION; MALE; NERVE CELL EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERFORANT NERVE TRACT; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; OLIGONUCLEOTIDES, ANTISENSE; RATS; RATS, SPRAGUE-DAWLEY; SYNAPTIC TRANSMISSION;

EID: 0030961682     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00013-0     Document Type: Article

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