Heat shock induces IκB-α and prevents stress-induced endothelial cell apoptosis

Archives of Surgery

Volumn 132, Issue 12, 1997, Pages 1283-1288

  DeMeester, Susan L ^a   Buchman, Timothy G ^a   Qiu, Yuyu ^a   Jacob, Ammini K ^a   Dunnigan, Keith ^a   Hotchkiss, Richard S ^a   Karl, Irene ^a   Cobb, J Perren ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b School of Medicine ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENITE SODIUM; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; ENDOTHELIUM CELL; HEAT STRESS; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SWINE;

EID: 0031454104     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: 10.1001/archsurg.1997.01430360029005     Document Type: Article

References (19)

1. Cobb JP, Hotchkiss RS, Karl I, Buchman TG. Mechanisms of cell injury and death. Br J Anaesth. 1996;77:3-11.
2. Buchman TG, Abello P, Smith E, Bulkley G. Induction of heat shock response leads to apoptosis in endothelial cells previously exposed to endotoxin. Am J Physiol. 1993;265:H165-H170.
3. Jacob A, Hotchkiss RS, DeMeester SL, et al. Endothelial cell apoptosis is accelerated by inorganic iron and heat via an oxygen-radical dependent mechanism. Surgery. 1997;122:243-254.
4. Abello P, Fidler SA, Bulkley G, Buchman TG. Antioxidants modulate induction of programmed endothelial cell death (apoptosis) by endotoxin. Arch Surg. 1994; 129:134-140.
5. DeMeester SL, Buchman TG, Hotchkiss RS, Upadhya G, Cobb JP. Pyrrolidine dithiocarbamate (PDTC) modulates NF-κB activity and endothelial cell (EC) apoptosis. Shock. 1996;5(suppl 2):72. Abstract.
6. Van Antwerp D, Martin S, Kafri T, Green DR, Verma I. Suppression of TNF-α-induced apoptosis by NF-κB. Science. 1996;274:787-789.
7. Beg A, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 1996;274:782-784.
8. Dignam J, Lebovitz R, Roeder R. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 1983;11:1473-1489.
9. Ferran C, Millan M, Csizmadia V, et al. Inhibition of NF-κB by pyrrolidine dithiocarbamate blocks endothelial cell activation. Biochem Biophys Res Commun. 1995; 214:212-223.
10. Minowada G, Welch WJ. Clinical implications of the stress response. J Clin Invest. 1995;95:3-12.
11. Samali A, Cotter T. Heat shock proteins increase resistance to apoptosis. Exp Cell Res. 1996;223:163-170.
12. Mailhos C, Howard MK, Latchman DS. Heat shock protects neuronal cells from programmed cell death by apoptosis. Neuroscience. 1993;55:621-627.
13. Mailhos C, Howard MK, Latchman DS. Heat shock proteins hsp90 and hsp70 protect neuronal cells from thermal stress but not from programmed cell death. J Neurochem. 1994;63:1787-1795.
14. Galea-Lauri J, Richardson A, Latchman D, Katz D. Increased heat shock protein 90 (hsp90) expression leads to increased apoptosis in the monoblastoid cell line U937 following the induction with TNFα and cycloheximide. J Immunol. 1996; 157:4109-4118.
15. DeMeester SL, Qui Y, Buchman TG, Cobb JP. Exogenous nitric oxide blocks stress-induced apoptosis in cultured endothelial cells. Shock. 1997:7(suppl 1):120. Abstract.
16. DeMeester SL, Qui Y, Buchman TG, Cobb JP. Pyrrolidine dithiocarbamate (PDTC) induces heat shock and apoptosis in primed endothelial cells. Shock. 1997;7 (suppl 1):117. Abstract.
17. Wong HR, Ryan M, Wispe JR. Stress response decreases NF-κ-B nuclear translocation and increases l-κ-B-α expression in A549 cells. J Clin Invest. 1997;99: 2423-2428.
18. Ribeiro S, Villar J, Downey G, Edelson J, Slutsky A. Sodium arsenite induces heat shock protein-72 kilodalton expression in the lungs and protects rats against sepsis. Crit Care Med. 1994;22:922-929.
19. Villar J, Ribeiro S, Mullen B, Kuliszewski M, Post M, Slutsky A. Induction of the heat shock response reduces mortality rate and organ damage in a sepsis-induced acute lung injury model. Crit Care Med. 1994;22:914-921.