Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit

Protein Science

Volumn 6, Issue 12, 1997, Pages 2644-2649

  Van Den Akker, F ^a,b   Feil, I K ^b   Roach, C ^b   Platas, A A ^b   Merritt, E A ^b   Hol, Wim G J ^a,b,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Cholera toxin; Disulfide bond; Heat labile enterotoxin; Protein engineering; Thermostability; X ray crystallography

Indexed keywords

CHOLERA TOXIN; DISULFIDE; ESCHERICHIA COLI ENTEROTOXIN; PROTEIN SUBUNIT;

ALPHA CHAIN; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; ESCHERICHIA COLI; GENETIC ENGINEERING; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; THERMOSTABILITY; VIBRIO CHOLERAE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; VIBRIO CHOLERAE;

EID: 0031453964     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560061219     Document Type: Article

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