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Volumn 42, Issue 2, 1997, Pages 76-85

Pharmacology and toxicology of the A(2A)-adenosine receptor agonist 2-[(cyclohexylmethylene)hydrazino]adenosine (MRE-0470) in the rat

Author keywords

Adenosine agonist; Adenosine receptors; Blood pressure; Cardiovascular; Heart rate

Indexed keywords

4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR; BINODENOSON; GLYCERYL TRINITRATE; ISOPRENALINE; UNCLASSIFIED DRUG;

EID: 0031447674     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199710)42:2<76::AID-DDR4>3.0.CO;2-M     Document Type: Article
Times cited : (5)

References (18)
  • 3
    • 26844502187 scopus 로고    scopus 로고
    • The myocardial lesions produced by the potassium channel opener aprikalim in monkeys and rats are prevented by blockade of cardiac beta-adrenoceptors
    • Belin V, Hodge T, Picaut P, Jordan R, Algate C, Gosselin S, Nohynek G, Cavero I (1996): The myocardial lesions produced by the potassium channel opener aprikalim in monkeys and rats are prevented by blockade of cardiac beta-adrenoceptors. Fundam Appl Toxicol 31:259-267.
    • (1996) Fundam Appl Toxicol , vol.31 , pp. 259-267
    • Belin, V.1    Hodge, T.2    Picaut, P.3    Jordan, R.4    Algate, C.5    Gosselin, S.6    Nohynek, G.7    Cavero, I.8
  • 4
    • 0027240062 scopus 로고
    • Adenosine induced broncho-constriction and its inhibition by nedocromil sodium
    • Church MK, Holgate ST (1993): Adenosine induced broncho-constriction and its inhibition by nedocromil sodium. J Allergy Clin Immunol 92:190-194.
    • (1993) J Allergy Clin Immunol , vol.92 , pp. 190-194
    • Church, M.K.1    Holgate, S.T.2
  • 5
    • 0030612311 scopus 로고    scopus 로고
    • 2 receptor function in rat ventricular myocytes
    • 2 receptor function in rat ventricular myocytes. Cardiovasc Res 34:337-347.
    • (1997) Cardiovasc Res , vol.34 , pp. 337-347
    • Dobson, J.G.1    Fenton, R.A.2
  • 7
    • 0028972108 scopus 로고
    • 2B receptor evoke interleukin-8 secretion in human mast cells, an enprofyllne-sensitive mechanism with implications for asthma
    • 2B receptor evoke interleukin-8 secretion in human mast cells, an enprofyllne-sensitive mechanism with implications for asthma. J Clin Invest 96:1979-1986.
    • (1995) J Clin Invest , vol.96 , pp. 1979-1986
    • Feoktistov, I.1    Biaggioni, I.2
  • 8
    • 0027513240 scopus 로고
    • 2 receptor agonists in the pithed rat: No role for glibenclamide-sensitive potassium channels
    • 2 receptor agonists in the pithed rat: No role for glibenclamide-sensitive potassium channels. Naunyn-Schmeideb Arch Pharmacol 347:192-196.
    • (1993) Naunyn-Schmeideb Arch Pharmacol , vol.347 , pp. 192-196
    • Fozard, J.R.1    Carruthers, A.M.2
  • 11
    • 0027445337 scopus 로고
    • 2 adenosine receptors in the aorta and coronary vessels from the guinea pig
    • 2 adenosine receptors in the aorta and coronary vessels from the guinea pig. J Pharmacol Exp Ther 265:248-253.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 248-253
    • Martin, P.L.1    Ueeda, M.2    Olsson, R.A.3
  • 13
    • 0027053077 scopus 로고
    • 2-(N′Alkylidenehydrazino)adenosines: Potent and selective coronary vasodilators
    • Niiya K, Olsson RA, Thompson RD, Silvia RD, Ueeda M (1992): 2-(N′Alkylidenehydrazino)adenosines: Potent and selective coronary vasodilators. J Med Chem 35:4557-4561.
    • (1992) J Med Chem , vol.35 , pp. 4557-4561
    • Niiya, K.1    Olsson, R.A.2    Thompson, R.D.3    Silvia, R.D.4    Ueeda, M.5
  • 15
    • 0027337474 scopus 로고
    • 3-adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells
    • 3-adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J Biol Chem 23:16887-16890.
    • (1993) J Biol Chem , vol.23 , pp. 16887-16890
    • Ramkumar, V.1    Stiles, G.L.2    Beaven, M.A.3    Ali, H.4
  • 17
    • 0027338414 scopus 로고
    • 2-adenosine receptor agonists do not alter action potential duration, twitch shortening, or cAMP accumulation in guinea pig, rat or rabbit isolated ventricular myocytes
    • 2-adenosine receptor agonists do not alter action potential duration, twitch shortening, or cAMP accumulation in guinea pig, rat or rabbit isolated ventricular myocytes. Circ Res 72:194-205.
    • (1993) Circ Res , vol.72 , pp. 194-205
    • Shryock, J.1    Song, Y.2    Wang, D.3    Baker, S.P.4    Olsson, R.A.5    Belardinelli, L.6
  • 18
    • 0026350047 scopus 로고
    • 2 agonists in the conscious spontaneously hypertensive rat: A comparative study of three structurally distinct ligands
    • 2 agonists in the conscious spontaneously hypertensive rat: A comparative study of three structurally distinct ligands. J Pharmacol Exp Ther 259:1203-1212.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 1203-1212
    • Webb, R.L.1    Barclay, B.W.2    Graybill, S.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.