Thermal atropisomerism of fully functinalized vancomycin CD, DE, and CDE ring systems

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 24, 1997, Pages 3199-3202

  Boger, Dale L ^a   Loiseleur, Olivier ^a   Castle, Steven L ^a   Beresis, Richard T ^a   Wu, Jason H ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VANCOMYCIN; VANCOMYCIN DERIVATIVE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; ISOMERISM; STEREOCHEMISTRY;

EID: 0031442227     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10182-2     Document Type: Article

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26. 1/2 = 2.52 h, 4a:4b = l .6:l.
27. The synthesis and characterization will be disclosed elsewhere.
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31. 1H NMR in deuterated solvents, see ref 9.