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Volumn 87, Issue 6, 1997, Pages 1309-1317

Systemic absorption and block after epidural injection of ropivacaine in healthy volunteers

Author keywords

Anesthesia, epidural; Disposition; Elimination; Isotope technique; Pharmacokinetics; Ropivacaine

Indexed keywords

PRILOCAINE; ROPIVACAINE; TRITIUM;

EID: 0031439403     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199712000-00008     Document Type: Article
Times cited : (59)

References (31)
  • 1
    • 0016430578 scopus 로고
    • Evaluation of the toxicity of local anaesthetic agents in man
    • Scott DB: Evaluation of the toxicity of local anaesthetic agents in man. Br J Anaesth 1975; 47:56-60
    • (1975) Br J Anaesth , vol.47 , pp. 56-60
    • Scott, D.B.1
  • 2
    • 0016467703 scopus 로고
    • Pharmacokinetics of local anaesthetic agents
    • Tucker GT, Mather LE: Pharmacokinetics of local anaesthetic agents. Br J Anaesth 1975; 47:213-24
    • (1975) Br J Anaesth , vol.47 , pp. 213-224
    • Tucker, G.T.1    Mather, L.E.2
  • 3
    • 0023731286 scopus 로고
    • Primary evaluation of the local anaesthetic properties of the amino amide agent ropivacaine (LEA 103)
    • Åkerman B, Hellberg I-B, Trossvik C: Primary evaluation of the local anaesthetic properties of the amino amide agent ropivacaine (LEA 103). Acta Anaesthesiol Scand 1988; 32:571-8
    • (1988) Acta Anaesthesiol Scand , vol.32 , pp. 571-578
    • Åkerman, B.1    Hellberg, I.-B.2    Trossvik, C.3
  • 4
    • 0023798712 scopus 로고
    • Comparative motor-blocking effects of bupivacaine and ropivacaine, a new amino amide local anesthetic in the rat and dog
    • Feldman HS, Covino BG: Comparative motor-blocking effects of bupivacaine and ropivacaine, a new amino amide local anesthetic in the rat and dog. Anesth Analg 1988; 67:1047-52
    • (1988) Anesth Analg , vol.67 , pp. 1047-1052
    • Feldman, H.S.1    Covino, B.G.2
  • 5
    • 0023815612 scopus 로고
    • Comparative pharmacokinetics of bupivacaine and ropivacaine, a new amide local anesthetic
    • Arthur GR, Feldman HS, Covino BG: Comparative pharmacokinetics of bupivacaine and ropivacaine, a new amide local anesthetic. Anesth Analg 1988; 67:1053-8
    • (1988) Anesth Analg , vol.67 , pp. 1053-1058
    • Arthur, G.R.1    Feldman, H.S.2    Covino, B.G.3
  • 6
    • 0024799198 scopus 로고
    • Hemodynamic and central nervous system effects of intravenous bolus doses of lidocaine, bupivacaine, and ropivacaine in sheep
    • Rutten AJ, Nancarrow C, Mather LE, Ilsley AH, Runciman WB, Upton RN: Hemodynamic and central nervous system effects of intravenous bolus doses of lidocaine, bupivacaine, and ropivacaine in sheep. Anesth Analg 1989; 69:291-9
    • (1989) Anesth Analg , vol.69 , pp. 291-299
    • Rutten, A.J.1    Nancarrow, C.2    Mather, L.E.3    Ilsley, A.H.4    Runciman, W.B.5    Upton, R.N.6
  • 10
    • 0022541667 scopus 로고
    • Estimation of drug absorption rates using a deconvolution method with nonequal sampling times
    • Iga K, Ogawa Y, Yashiki T, Shimamoto T: Estimation of drug absorption rates using a deconvolution method with nonequal sampling times. J Pharmacokin Biopharm 1986; 14:213-25
    • (1986) J Pharmacokin Biopharm , vol.14 , pp. 213-225
    • Iga, K.1    Ogawa, Y.2    Yashiki, T.3    Shimamoto, T.4
  • 14
    • 0023414508 scopus 로고
    • Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration. Simultaneous investigation of absorption and disposition kinetics using stable isotopes
    • Burm AGL, Vermeulen NPE, van Kleef JW, de Boer AG, Spierdijk J, Breimer DD: Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration. Simultaneous investigation of absorption and disposition kinetics using stable isotopes. Clin Pharmacokinet 1987; 13:191-203
    • (1987) Clin Pharmacokinet , vol.13 , pp. 191-203
    • Burm, A.G.L.1    Vermeulen, N.P.E.2    Van Kleef, J.W.3    De Boer, A.G.4    Spierdijk, J.5    Breimer, D.D.6
  • 15
    • 0018646720 scopus 로고
    • Clinical pharmacokinetics of local anaesthetics
    • Tucker GT, Mather LE: Clinical pharmacokinetics of local anaesthetics. Clin Pharmacokinet 1979; 4:241-78
    • (1979) Clin Pharmacokinet , vol.4 , pp. 241-278
    • Tucker, G.T.1    Mather, L.E.2
  • 17
    • 0030962927 scopus 로고    scopus 로고
    • Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers
    • Knudsen K, Beckman Suurküla M, Blomberg S, Sjövall J, Edvardsson N: Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers. Br J Anaesth 1997; 78:507-14
    • (1997) Br J Anaesth , vol.78 , pp. 507-514
    • Knudsen, K.1    Beckman Suurküla, M.2    Blomberg, S.3    Sjövall, J.4    Edvardsson, N.5
  • 19
    • 0028789687 scopus 로고
    • Pharmacokinetics of ropivacaine and bupivacaine during 21 hours of continuous epidural infusion in healthy male volunteers
    • Emanuelsson B-M, Dusanka Z, Nydahl P-A, Axelsson K: Pharmacokinetics of ropivacaine and bupivacaine during 21 hours of continuous epidural infusion in healthy male volunteers. Anesth Analg 1995; 81:1163-8
    • (1995) Anesth Analg , vol.81 , pp. 1163-1168
    • Emanuelsson, B.-M.1    Dusanka, Z.2    Nydahl, P.-A.3    Axelsson, K.4
  • 20
    • 0030020458 scopus 로고    scopus 로고
    • Ropivacaine
    • McClure JH: Ropivacaine. Br J Anaesth 1996; 76:300-7
    • (1996) Br J Anaesth , vol.76 , pp. 300-307
    • McClure, J.H.1
  • 23
    • 0014102142 scopus 로고
    • Epidural pressure and its relation to spread of anesthetic solutions in epidural space
    • Usubiaga JE, Wikinski JA, Usubiaga LE: Epidural pressure and its relation to spread of anesthetic solutions in epidural space. Anesth Analg Curr Res 1967; 46:440-6
    • (1967) Anesth Analg Curr Res , vol.46 , pp. 440-446
    • Usubiaga, J.E.1    Wikinski, J.A.2    Usubiaga, L.E.3
  • 25
    • 0024461323 scopus 로고
    • The Phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (part II)
    • Chiou WL: The Phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (part II). Clin Pharmacokinet 1989; 17:275-90
    • (1989) Clin Pharmacokinet , vol.17 , pp. 275-290
    • Chiou, W.L.1
  • 26
    • 0024442139 scopus 로고
    • The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (part I)
    • Chiou WL: The phenomenon and rationale of marked dependence of drug concentration on blood sampling site. Implications in pharmacokinetics, pharmacodynamics, toxicology and therapeutics (part I). Clin Pharmacokinet 1989; 17:175-99
    • (1989) Clin Pharmacokinet , vol.17 , pp. 175-199
    • Chiou, W.L.1
  • 27
    • 0031442096 scopus 로고    scopus 로고
    • Intraindividual and interindividual variability in the disposition of the local anesthetic ropivacaine in healthy subjects
    • Emanuelsson B-M, Persson J, Sandin S, Alm C, Gustafsson LL: Intraindividual and interindividual variability in the disposition of the local anesthetic ropivacaine in healthy subjects. Ther Drug Monit 1997; 19:126-31
    • (1997) Ther Drug Monit , vol.19 , pp. 126-131
    • Emanuelsson, B.-M.1    Persson, J.2    Sandin, S.3    Alm, C.4    Gustafsson, L.L.5
  • 29
    • 0015146611 scopus 로고
    • Simultaneous systemic and hepatic hemodynamic measurements during high peridural anesthesia in normal man
    • Kennedy WF Jr, Everett GB, Cobb LA, Allen GD: Simultaneous systemic and hepatic hemodynamic measurements during high peridural anesthesia in normal man. Anesth Analg 1971; 50:1069-77
    • (1971) Anesth Analg , vol.50 , pp. 1069-1077
    • Kennedy W.F., Jr.1    Everett, G.B.2    Cobb, L.A.3    Allen, G.D.4
  • 31
    • 0016566218 scopus 로고
    • A physiological approach to hepatic clearance
    • Wilkinson GR, Shand DG: A physiological approach to hepatic clearance. Clin Pharmacol Ther 1975; 18:377-90
    • (1975) Clin Pharmacol Ther , vol.18 , pp. 377-390
    • Wilkinson, G.R.1    Shand, D.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.