Intraindividual and interindividual variability in the disposition of the local anesthetic ropivacaine in the healthy subjects

Therapeutic Drug Monitoring

Volumn 19, Issue 2, 1997, Pages 126-131

  Emanuelsson, B M ^a,c   Persson, J ^b   Sandin, S ^a   Alm, C ^b   Gustafsson, L L ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Research and Development at Scania Technical Centre   (Sweden)

Author keywords

Healthy volunteers; Local anesthetics; Pharmacokinetics; Ropivacaine

Indexed keywords

ACUTE PHASE PROTEIN; OROSOMUCOID; ROPIVACAINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; HUMAN; HUMAN EXPERIMENT; IMMUNODIFFUSION; INTRAVENOUS DRUG ADMINISTRATION; LIQUID CHROMATOGRAPHY; MALE; NEUROTOXICITY; NORMAL HUMAN; PARESTHESIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STEADY STATE;

ADULT; AMIDES; ANESTHETICS, LOCAL; DOUBLE-BLIND METHOD; HUMANS; INJECTIONS, INTRAVENOUS; MALE;

EID: 0031442096     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199704000-00002     Document Type: Article

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