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Volumn 25, Issue 12, 1997, Pages 1354-1358

Cytochrome P450 isozymes involved in lisofylline metabolism to pentoxifylline in human liver microsomes

Author keywords

[No Author keywords available]

Indexed keywords

BENZOTRIAZOLE DERIVATIVE; CYTOCHROME P450; LISOFYLLINE; OCTAMYLAMINE; PENTOXIFYLLINE;

EID: 0031435602     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (37)
  • 1
    • 0344969966 scopus 로고    scopus 로고
    • Serum hydroperoxy and hydroxyoctadecadienoic acids (HPODE and HODE) increase in response to total body irradiation and are suppressed by lysofylline in allogenic BMT patients
    • in press
    • J. W. Singer, A. List, D. Federighi, T. Michnick, and S. Bursten: Serum hydroperoxy and hydroxyoctadecadienoic acids (HPODE and HODE) increase in response to total body irradiation and are suppressed by lysofylline in allogenic BMT patients. Blood, in press.
    • Blood
    • Singer, J.W.1    List, A.2    Federighi, D.3    Michnick, T.4    Bursten, S.5
  • 2
    • 0029908319 scopus 로고    scopus 로고
    • Lysofylline decreases white cell adhesiveness and improves survial after experimental hemorrhagic shock
    • K. Waxman, K. Daughters, S. Aswani, and G. Rice. Lysofylline decreases white cell adhesiveness and improves survial after experimental hemorrhagic shock. Crit. Care Med. 24, 1724-1728 (1996).
    • (1996) Crit. Care Med. , vol.24 , pp. 1724-1728
    • Waxman, K.1    Daughters, K.2    Aswani, S.3    Rice, G.4
  • 4
    • 0028214828 scopus 로고
    • Pentoxifylline for intermittent claudication: A critical review
    • E. Ernst: Pentoxifylline for intermittent claudication: a critical review. Angiology 45, 339-345 (1994).
    • (1994) Angiology , vol.45 , pp. 339-345
    • Ernst, E.1
  • 5
    • 0025998492 scopus 로고
    • Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation
    • J. A. Bianco, F. R. Appelbaum, J. Nemunaitis, J. Almgren, F. Andrews, P. Kettner, A. Shields, and J. W. Singer: Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation. Blood 78, 1205-1211 (1991).
    • (1991) Blood , vol.78 , pp. 1205-1211
    • Bianco, J.A.1    Appelbaum, F.R.2    Nemunaitis, J.3    Almgren, J.4    Andrews, F.5    Kettner, P.6    Shields, A.7    Singer, J.W.8
  • 6
    • 0028228294 scopus 로고
    • Phase Ib trial of pentoxifylline and ciprofloxacin in patients treated with interleukin-2 and lymphokine-activated killer cell therapy for metastatic renal cell carcinoma
    • J. A. Thompson, J. A. Bianco, M. C. Benyunes, M. A. Neubauer, J. T. Slattery, and A. Feber: Phase Ib trial of pentoxifylline and ciprofloxacin in patients treated with interleukin-2 and lymphokine-activated killer cell therapy for metastatic renal cell carcinoma. Cancer Res. 54, 3436-3441 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 3436-3441
    • Thompson, J.A.1    Bianco, J.A.2    Benyunes, M.C.3    Neubauer, M.A.4    Slattery, J.T.5    Feber, A.6
  • 7
    • 0028327157 scopus 로고
    • Pentoxifylline for the treatment of infection with human immunodeficiency virus
    • B. J. Dezube: Pentoxifylline for the treatment of infection with human immunodeficiency virus. Clin. Infect. Dis. 18, 285-287 (1994).
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 285-287
    • Dezube, B.J.1
  • 8
    • 0028089362 scopus 로고
    • Use of pentoxifylline therapy for patients with AIDS-related wasting: Pilot study
    • D. Landman, A. Sarai, and S. S. Sathe: Use of pentoxifylline therapy for patients with AIDS-related wasting: pilot study. Clin. Infect. Dis. 18, 97-99 (1994).
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 97-99
    • Landman, D.1    Sarai, A.2    Sathe, S.S.3
  • 9
    • 0027363219 scopus 로고
    • Clinical update on pentoxifylline therapy for diabetes-induced peripheral vascular disease
    • R. K. Campbell: Clinical update on pentoxifylline therapy for diabetes-induced peripheral vascular disease. Ann. Pharmacother. 27, 1099-1105 (1993).
    • (1993) Ann. Pharmacother. , vol.27 , pp. 1099-1105
    • Campbell, R.K.1
  • 10
    • 0027288806 scopus 로고
    • Sperm treatment with pentoxifylline improves the fertilizing ability in patients with acrosome reaction insufficiency
    • J. Tesarik and C. Mendoza: Sperm treatment with pentoxifylline improves the fertilizing ability in patients with acrosome reaction insufficiency. Fertil. Steril. 60, 141-148 (1993).
    • (1993) Fertil. Steril. , vol.60 , pp. 141-148
    • Tesarik, J.1    Mendoza, C.2
  • 11
    • 0028232726 scopus 로고
    • Pentoxifylline in idiopathic male-factor infertility: A review of its therapeutic efficacy after oral administration
    • H. Tournaye, A. C. Van Steirteghem, and P. Devroey: Pentoxifylline in idiopathic male-factor infertility: a review of its therapeutic efficacy after oral administration. Hum. Reprod. 9, 996-1000 (1994).
    • (1994) Hum. Reprod. , vol.9 , pp. 996-1000
    • Tournaye, H.1    Van Steirteghem, A.C.2    Devroey, P.3
  • 12
    • 0030614470 scopus 로고    scopus 로고
    • Pentoxifylline, a drug with Theological effects, decreases portal pressure in an experimental model of cirrhosis
    • S. Sanchez, L. Albornoz, J. C. Bandi, S. Gerona, and R. Mastai: Pentoxifylline, a drug with Theological effects, decreases portal pressure in an experimental model of cirrhosis. Eur. J. Gastroenterol. Hepatol. 9, 27-31 (1997).
    • (1997) Eur. J. Gastroenterol. Hepatol. , vol.9 , pp. 27-31
    • Sanchez, S.1    Albornoz, L.2    Bandi, J.C.3    Gerona, S.4    Mastai, R.5
  • 13
    • 0030465955 scopus 로고    scopus 로고
    • Effect of pentoxifylline on renal toxicity of cyclosporine: Results of a clinical trial after heart transplantation
    • M. Carrier, G. B. Pelletier, M. White, D. Bois, and L. C. Delletier: Effect of pentoxifylline on renal toxicity of cyclosporine: Results of a clinical trial after heart transplantation. J. Heart Lung Transplant. 15, 1179-1183 (1996).
    • (1996) J. Heart Lung Transplant. , vol.15 , pp. 1179-1183
    • Carrier, M.1    Pelletier, G.B.2    White, M.3    Bois, D.4    Delletier, L.C.5
  • 14
    • 0015367204 scopus 로고
    • Struktur der ausscheidung sprodukte des 3.7-dimethyl-1-(5-oxo-hexyl)-xanthines (BL 191) beim menschen
    • H. J. Von Hinze, G. Bedebem, and A. Söde: Struktur der ausscheidung sprodukte des 3.7-dimethyl-1-(5-oxo-hexyl)-xanthines (BL 191) beim menschen. Arzneimittelforschung 22, 1144-1151 (1972).
    • (1972) Arzneimittelforschung , vol.22 , pp. 1144-1151
    • Von Hinze, H.J.1    Bedebem, G.2    Söde, A.3
  • 16
    • 0026503075 scopus 로고
    • Determination of pentoxifylline and its metabolites in human plasma by high performance liquid chromatography with solid-phase extraction
    • A. Mancinelli, S. Pace, A. Marzo, and E. A. Martelli: Determination of pentoxifylline and its metabolites in human plasma by high performance liquid chromatography with solid-phase extraction. J. Chromatogr. 575, 101-107 (1992).
    • (1992) J. Chromatogr. , vol.575 , pp. 101-107
    • Mancinelli, A.1    Pace, S.2    Marzo, A.3    Martelli, E.A.4
  • 17
    • 0030476589 scopus 로고    scopus 로고
    • Metabolism of lisofylline and pentoxifylline in human liver microsomes and cytosol
    • J. A. Lillibridge, T. F. Kalhorn, and J. T. Slattery: Metabolism of lisofylline and pentoxifylline in human liver microsomes and cytosol. Drug Metab. Dispos. 24, 1174-1179 (1996).
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 1174-1179
    • Lillibridge, J.A.1    Kalhorn, T.F.2    Slattery, J.T.3
  • 19
    • 0027380074 scopus 로고
    • Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline
    • K. L. Kunze and W. F. Trager: Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline. Chem. Res. Toxicol. 6, 649-656 (1993).
    • (1993) Chem. Res. Toxicol. , vol.6 , pp. 649-656
    • Kunze, K.L.1    Trager, W.F.2
  • 20
    • 0028858960 scopus 로고
    • Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
    • D. J. Newton, R. W. Wang, and A. Y. H. Lu: Cytochrome P450 inhibitors: evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab. Dispos. 23, 154-158 (1995).
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 154-158
    • Newton, D.J.1    Wang, R.W.2    Lu, A.Y.H.3
  • 21
    • 0025214234 scopus 로고
    • Identification of the human liver cytochrome P450 responsible for coumarin 7-hydroxylase activity
    • J. S. Miles, A. W. McLaren, L. M. Forrester, M. J. Glancey, M. A. Lang, and C. R. Wolf: Identification of the human liver cytochrome P450 responsible for coumarin 7-hydroxylase activity. Biochem. J. 267, 365-371 (1990).
    • (1990) Biochem. J. , vol.267 , pp. 365-371
    • Miles, J.S.1    McLaren, A.W.2    Forrester, L.M.3    Glancey, M.J.4    Lang, M.A.5    Wolf, C.R.6
  • 22
    • 0024319135 scopus 로고
    • Inhibition of oxidative drug metabolism by orphenadrine: In vitro evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics
    • G. F. Reidy, I. Mehta, and M. Murray: Inhibition of oxidative drug metabolism by orphenadrine: in vitro evidence for isozyme-specific complexation of cytochrome P-450 and inhibition kinetics. Mol. Pharmacol. 35, 736-743 (1989).
    • (1989) Mol. Pharmacol. , vol.35 , pp. 736-743
    • Reidy, G.F.1    Mehta, I.2    Murray, M.3
  • 23
    • 0025014594 scopus 로고
    • Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP 2C subfamily
    • M. V. Relling, T. Aoyama, F. J. Gonzalez, and U. A. Meyer: Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP 2C subfamily. J. Pharmacol. Exp. Ther. 252, 442-447 (1990).
    • (1990) J. Pharmacol. Exp. Ther. , vol.252 , pp. 442-447
    • Relling, M.V.1    Aoyama, T.2    Gonzalez, F.J.3    Meyer, U.A.4
  • 27
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome P450 2C19: Correlation between 2C19 and. S-mephenytoin 4′hydroxylation
    • S. A. Wrighton, J. C. Stevens, G. W. Becker, and M. VandenBraden: Isolation and characterization of human liver cytochrome P450 2C19: Correlation between 2C19 and. S-mephenytoin 4′hydroxylation. Arch. Biochem. Biophys. 306, 240-245 (1993).
    • (1993) Arch. Biochem. Biophys. , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    VandenBraden, M.4
  • 29
    • 0022390883 scopus 로고
    • In vitro inhibition studies of two isozymes of human liver cytochrome P450; Mephenytoin P-hydroxylase and spartein monooxygenase
    • T. Inaba, M. Jurima, W. A. Mahon, and W. Kalow: In vitro inhibition studies of two isozymes of human liver cytochrome P450; Mephenytoin P-hydroxylase and spartein monooxygenase. Drug. Metab. Dispos. 13, 443-448 (1985).
    • (1985) Drug. Metab. Dispos. , vol.13 , pp. 443-448
    • Inaba, T.1    Jurima, M.2    Mahon, W.A.3    Kalow, W.4
  • 30
    • 0022467917 scopus 로고
    • Oxidation of quinidine by human liver microsomal P450
    • F. P. Guengerich, D. Muller-Enoch, and I. A. Blair: Oxidation of quinidine by human liver microsomal P450. Mol. Pharmacol. 30, 287-295 (1986).
    • (1986) Mol. Pharmacol. , vol.30 , pp. 287-295
    • Guengerich, F.P.1    Muller-Enoch, D.2    Blair, I.A.3
  • 31
    • 0026035519 scopus 로고
    • Role of human cytochrome P450 IIE1 in the oxidation of several low molecular weight cancer suspects
    • F. P. Guengerich, D. M. Kim, and M. Iwasaki: Role of human cytochrome P450 IIE1 in the oxidation of several low molecular weight cancer suspects. Chem. Res. Toxicol. 4, 168-179 (1991).
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.M.2    Iwasaki, M.3
  • 32
    • 0026744568 scopus 로고
    • Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkyl amines and tobacco-related nitrosamines in human liver microsomes
    • H. Yamazaki, Y. Inui, C-H. Yun, F. P. Guengerich, and T. Shimada: Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkyl amines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis 13, 1789-1794 (1992).
    • (1992) Carcinogenesis , vol.13 , pp. 1789-1794
    • Yamazaki, H.1    Inui, Y.2    Yun, C.-H.3    Guengerich, F.P.4    Shimada, T.5
  • 33
    • 0028174881 scopus 로고
    • Evaluation of triacetyloleandomycin, α-naphthoflavone, and diethyldithiocarbamate as selective chemical probe for inhibition of human cytochrome P450
    • T. K. Chang, F. J. Gonzalez, and D. J. Waxman: Evaluation of triacetyloleandomycin, α-naphthoflavone, and diethyldithiocarbamate as selective chemical probe for inhibition of human cytochrome P450. Arch. Biochem. Biophys. 311, 437-442 (1994).
    • (1994) Arch. Biochem. Biophys. , vol.311 , pp. 437-442
    • Chang, T.K.1    Gonzalez, F.J.2    Waxman, D.J.3
  • 34
    • 0024242448 scopus 로고
    • On the substrate specificities of cytochrome P450 IIIA1
    • M. J. Namkung, H. L. Yang, J. E. Hulla, and M. R. Juchau: On the substrate specificities of cytochrome P450 IIIA1. Mol. Pharmacol. 34, 628-637 (1988).
    • (1988) Mol. Pharmacol. , vol.34 , pp. 628-637
    • Namkung, M.J.1    Yang, H.L.2    Hulla, J.E.3    Juchau, M.R.4
  • 35
    • 0030430033 scopus 로고    scopus 로고
    • Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes
    • M. Bourrie, V. Meunier, Y. Berger, and G. Fabre: Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes. J. Pharmacol. Exp. Ther. 277, 321-332 (1996).
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 321-332
    • Bourrie, M.1    Meunier, V.2    Berger, Y.3    Fabre, G.4
  • 36
    • 0029877219 scopus 로고    scopus 로고
    • Warfarinfluconazole I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: In vitro studies
    • K. L. Kunze, L. C. Wienkers, K. E. Thummel, and W. F. Trager: Warfarinfluconazole I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: In vitro studies. Drug Metab. Dispos. 24, 414-421 (1996).
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 414-421
    • Kunze, K.L.1    Wienkers, L.C.2    Thummel, K.E.3    Trager, W.F.4
  • 37
    • 0027417453 scopus 로고
    • Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1
    • K. E. Thummel, E. D. Kharasch, T. Podoll, and K. L. Kunze: Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1. Drug Metab. Dispos. 21, 350-357 (1993).
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 350-357
    • Thummel, K.E.1    Kharasch, E.D.2    Podoll, T.3    Kunze, K.L.4


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