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Volumn 24, Issue 11, 1996, Pages 1174-1179

Metabolism of lisofylline and pentoxifylline in human liver microsomes and cytosol

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLYCOL; LISOFYLLINE; LYSOPHOSPHATIDIC ACID; PENTOXIFYLLINE; PHOSPHATIDIC ACID; PRODRUG;

EID: 0030476589     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (31)

References (29)
  • 1
    • 0028214828 scopus 로고
    • Pentoxifylline for intermittent claudication: A critical review
    • E. Ernst: Pentoxifylline for intermittent claudication: a critical review. Angiology 45, 339-345 (1994).
    • (1994) Angiology , vol.45 , pp. 339-345
    • Ernst, E.1
  • 2
    • 0025998492 scopus 로고
    • Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation
    • J. A. Bianco, F. R. Appelbaum, J. Nemunaitis, J. Almgren, F. Andrews, P. Kettner, A. Shields, and J. W. Singer: Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation. Blood 78, 1205-1211 (1991).
    • (1991) Blood , vol.78 , pp. 1205-1211
    • Bianco, J.A.1    Appelbaum, F.R.2    Nemunaitis, J.3    Almgren, J.4    Andrews, F.5    Kettner, P.6    Shields, A.7    Singer, J.W.8
  • 3
    • 0028228294 scopus 로고
    • Phase Ib trial of pentoxifylline and ciprofloxacin in patients treated with interleukin-2 and lymphokine-activated killer cell therapy for metastatic renal cell carcinoma
    • J. A. Thompson, J. A. Bianco, M. C. Benyunes, M. A. Neubauer, J. T. Slattery, and A. Fefer: Phase Ib trial of pentoxifylline and ciprofloxacin in patients treated with interleukin-2 and lymphokine-activated killer cell therapy for metastatic renal cell carcinoma. Cancer Res. 54, 3436-3441 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 3436-3441
    • Thompson, J.A.1    Bianco, J.A.2    Benyunes, M.C.3    Neubauer, M.A.4    Slattery, J.T.5    Fefer, A.6
  • 4
    • 0027288806 scopus 로고
    • Sperm treatment with pentoxifylline improves the fertilizing ability in patients with acrosome reaction insufficiency
    • J. Tesarik and C. Mendoza: Sperm treatment with pentoxifylline improves the fertilizing ability in patients with acrosome reaction insufficiency. Fertil. Steril. 60, 141-148 (1993).
    • (1993) Fertil. Steril. , vol.60 , pp. 141-148
    • Tesarik, J.1    Mendoza, C.2
  • 5
    • 0028232726 scopus 로고
    • Pentoxifylline in idiopathic male-factor infertility: A review of its therapeutic efficacy after oral administration
    • H. Tournaye, A. C. Van Steirteghem, and P. Devroey: Pentoxifylline in idiopathic male-factor infertility: a review of its therapeutic efficacy after oral administration. Hum. Reprod. 9, 996-1000 (1994).
    • (1994) Hum. Reprod. , vol.9 , pp. 996-1000
    • Tournaye, H.1    Van Steirteghem, A.C.2    Devroey, P.3
  • 6
    • 0028327157 scopus 로고
    • Pentoxifylline for the treatment of infection with human immunodeficiency virus
    • B. J. Dezube: Pentoxifylline for the treatment of infection with human immunodeficiency virus. Clin. Infect. Dis. 18, 285-287 (1994).
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 285-287
    • Dezube, B.J.1
  • 7
    • 0027363219 scopus 로고
    • Clinical update on pentoxifylline therapy for diabetes-induced peripheral vascular disease
    • R. K. Campbell: Clinical update on pentoxifylline therapy for diabetes-induced peripheral vascular disease. Ann. Pharmacother. 27, 1099-1105 (1993).
    • (1993) Ann. Pharmacother. , vol.27 , pp. 1099-1105
    • Campbell, R.K.1
  • 8
    • 0028089362 scopus 로고
    • Use of pentoxifylline therapy for patients with AIDS-related wasting: Pilot study
    • D. Landman, A. Sarai, and S. S. Sathe: Use of pentoxifylline therapy for patients with AIDS-related wasting: pilot study. Clin. Infect. Dis. 18, 97-99 (1994).
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 97-99
    • Landman, D.1    Sarai, A.2    Sathe, S.S.3
  • 9
    • 0027228499 scopus 로고
    • Prevention of regimen-related toxicities after bone marrow transplantation by pentoxifylline: A prospective, randomized trial
    • M. Attal, F. Huguet, H. Rubie, J. P. Charlet, D. Schlaifer, A. Huynh, G. Laurent, and J. Pris: Prevention of regimen-related toxicities after bone marrow transplantation by pentoxifylline: a prospective, randomized trial. Blood 82, 732-736 (1993).
    • (1993) Blood , vol.82 , pp. 732-736
    • Attal, M.1    Huguet, F.2    Rubie, H.3    Charlet, J.P.4    Schlaifer, D.5    Huynh, A.6    Laurent, G.7    Pris, J.8
  • 10
    • 0028036302 scopus 로고
    • Effect of pentoxifylline on regimen related toxicity in patients undergoing allogeneic or autologous bone marrow transplantation
    • R. H. C. van der Jagt, G. Pari, S. A. McDiarmid, D. M. Boisvert, and L. B. Huebsch: Effect of pentoxifylline on regimen related toxicity in patients undergoing allogeneic or autologous bone marrow transplantation. Bone Marrow Transplant. 13, 203-207 (1994).
    • (1994) Bone Marrow Transplant. , vol.13 , pp. 203-207
    • Van Der Jagt, R.H.C.1    Pari, G.2    McDiarmid, S.A.3    Boisvert, D.M.4    Huebsch, L.B.5
  • 13
    • 0015367204 scopus 로고
    • Struktur der ausscheidungsprodukte des 3,7-dimethyl-1-(5-oxo-hexyl)-xanthins (BL 191) beim menschen
    • H. J. Von Hinze, G. Bedebem, and A. Söder: Struktur der ausscheidungsprodukte des 3,7-dimethyl-1-(5-oxo-hexyl)-xanthins (BL 191) beim menschen. Arzneimittelforschung 22, 1144-1151 (1972).
    • (1972) Arzneimittelforschung , vol.22 , pp. 1144-1151
    • Von Hinze, H.J.1    Bedebem, G.2    Söder, A.3
  • 15
    • 0026503075 scopus 로고
    • Determination of pentoxifylline and its metabolites in human plasma by high-performance liquid chromatography with solid-phase extraction
    • A. Mancinelli, S. Pace, A. Marzo, and E. Arrigoni Martelli: Determination of pentoxifylline and its metabolites in human plasma by high-performance liquid chromatography with solid-phase extraction. J. Chromatogr. 575, 101-107 (1992).
    • (1992) J. Chromatogr. , vol.575 , pp. 101-107
    • Mancinelli, A.1    Pace, S.2    Marzo, A.3    Arrigoni Martelli, E.4
  • 16
    • 8044234000 scopus 로고
    • Ciprofloxacin (Cipro) and pentoxifylline (PTF): A clinically significant drug interaction
    • J. D. Cleary: Ciprofloxacin (Cipro) and pentoxifylline (PTF): a clinically significant drug interaction. Pharmacotherapy 12, 259 (1992).
    • (1992) Pharmacotherapy , vol.12 , pp. 259
    • Cleary, J.D.1
  • 17
    • 8044259259 scopus 로고    scopus 로고
    • Serum hydroperoxy and hydroxyoctadecadienoic acids (HPODE and HODE) increase in response to total body irradiation and are suppressed by lisofylline in allogeneic BMT patients
    • in press
    • J. W. Singer, A. List, D. Federighi, T. Michnick, and S. Bursten: Serum hydroperoxy and hydroxyoctadecadienoic acids (HPODE and HODE) increase in response to total body irradiation and are suppressed by lisofylline in allogeneic BMT patients. Blood, in press.
    • Blood
    • Singer, J.W.1    List, A.2    Federighi, D.3    Michnick, T.4    Bursten, S.5
  • 18
    • 0029908319 scopus 로고    scopus 로고
    • Lisofylline decreases white cell adhesiveness and improves survival after experimental hemorrhagic shock
    • in press
    • K. Waxman, K. Daughters, and S. Aswani: Lisofylline decreases white cell adhesiveness and improves survival after experimental hemorrhagic shock. Crit. Care Med. in press.
    • Crit. Care Med.
    • Waxman, K.1    Daughters, K.2    Aswani, S.3
  • 20
    • 0027253615 scopus 로고
    • Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4
    • K. E. Thummel, C. A. Lee, K. L. Kunze, S. D. Nelson, and J. T. Slattery: Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4. Biochem. Pharamcol. 45, 1563-1569 (1993).
    • (1993) Biochem. Pharamcol. , vol.45 , pp. 1563-1569
    • Thummel, K.E.1    Lee, C.A.2    Kunze, K.L.3    Nelson, S.D.4    Slattery, J.T.5
  • 21
    • 0027417453 scopus 로고
    • Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1
    • K. E. Thummel, E. D. Kharasch, T. Podoll, and K. Kunze: Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1. Drug Metab. Dispos. 21, 350-357 (1993).
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 350-357
    • Thummel, K.E.1    Kharasch, E.D.2    Podoll, T.3    Kunze, K.4
  • 22
  • 23
    • 0027415804 scopus 로고
    • Suppression of OKT3-induced tumor necrosis factor alpha formation by pentoxifylline in renal transplant recipients
    • G. Leimenstoll, P. Zabel, P. Schroeder, M. Schlaak, and W. Niedermayer: Suppression of OKT3-induced tumor necrosis factor alpha formation by pentoxifylline in renal transplant recipients. Transplant. Proc. 25, 561-563 (1993).
    • (1993) Transplant. Proc. , vol.25 , pp. 561-563
    • Leimenstoll, G.1    Zabel, P.2    Schroeder, P.3    Schlaak, M.4    Niedermayer, W.5
  • 25
  • 26
    • 0027537059 scopus 로고
    • Procoagulant properties of OKT3 at the monocyte level: Inhibition by pentoxifylline
    • O. Pradier, D. Abramowicz, P. Capel, and M. Goldman: Procoagulant properties of OKT3 at the monocyte level: inhibition by pentoxifylline. Transplant. Proc. 25, 39-40 (1993).
    • (1993) Transplant. Proc. , vol.25 , pp. 39-40
    • Pradier, O.1    Abramowicz, D.2    Capel, P.3    Goldman, M.4
  • 27
    • 0001793867 scopus 로고
    • Effects of pentoxifylline on circulating cytokines (TNF and IL-6) in severe pulmonary tuberculosis
    • W. Fiers and W. A. Buurman, eds., Basel, Karger
    • P. Zabel, U. Greinert, P. Entzian, and M. Schlaak: Effects of pentoxifylline on circulating cytokines (TNF and IL-6) in severe pulmonary tuberculosis. In "Tumor Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance" (W. Fiers and W. A. Buurman, eds.), pp. 178-181. Basel, Karger, 1993.
    • (1993) Tumor Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance , pp. 178-181
    • Zabel, P.1    Greinert, U.2    Entzian, P.3    Schlaak, M.4
  • 29
    • 0027006496 scopus 로고
    • Pentoxifylline in vitro reverses neutrophil chemotactic deficiency induced by interleukin-2 treatment
    • C. Fossat, D. Sainty, A. M. Stoppa, D. Maraninchi, and I. Juhan-Vague: Pentoxifylline in vitro reverses neutrophil chemotactic deficiency induced by interleukin-2 treatment. Nouv. Rev. Fr. Hematol. 34, S61-S64 (1992).
    • (1992) Nouv. Rev. Fr. Hematol. , vol.34
    • Fossat, C.1    Sainty, D.2    Stoppa, A.M.3    Maraninchi, D.4    Juhan-Vague, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.