메뉴 건너뛰기




Volumn 64, Issue 12, 1997, Pages 1816-1822

CD28-B7 T-cell co-stimulatory blockade potentiates the effects of intrathymic immunomodulation in sensitized graft recipients

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; B7 ANTIGEN; CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MONOCLONAL ANTIBODY;

EID: 0031435310     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199712270-00032     Document Type: Conference Paper
Times cited : (5)

References (48)
  • 1
    • 0026546882 scopus 로고
    • Factors affecting the waiting time of cadaveric kidney transplant candidates in the United States
    • Sanfilippo FP, Vaughn WK, Peters TG, et al. Factors affecting the waiting time of cadaveric kidney transplant candidates in the United States. JAMA 1992; 267: 247.
    • (1992) JAMA , vol.267 , pp. 247
    • Sanfilippo, F.P.1    Vaughn, W.K.2    Peters, T.G.3
  • 2
    • 0028337520 scopus 로고
    • Intrathymic injection of donor-specific x-irradiation-sensitive spleen cells abrogates accelerated rejection of cardiac allografts in sensitized rats
    • Binder J, Sayegh MH, Watschinger B, Hancock WW, Kupiec-Weglinski JW. Intrathymic injection of donor-specific x-irradiation-sensitive spleen cells abrogates accelerated rejection of cardiac allografts in sensitized rats. Transplantation 1994; 58: 80.
    • (1994) Transplantation , vol.58 , pp. 80
    • Binder, J.1    Sayegh, M.H.2    Watschinger, B.3    Hancock, W.W.4    Kupiec-Weglinski, J.W.5
  • 4
    • 0029621959 scopus 로고
    • Downregulation of intragraft IFN-γ expression correlates with increased IgG1 alloantibody response following intrathymic immunomodulation of sensitized rat recipients
    • Binder J, Graser E, Hancock WW, et al. Downregulation of intragraft IFN-γ expression correlates with increased IgG1 alloantibody response following intrathymic immunomodulation of sensitized rat recipients. Transplantation 1995; 60: 1516.
    • (1995) Transplantation , vol.60 , pp. 1516
    • Binder, J.1    Graser, E.2    Hancock, W.W.3
  • 6
    • 0026540685 scopus 로고
    • Evidence of the central role of the thymus in the induction of donor-specific unresponsiveness to a renal allograft
    • Perico N, Rossini M, Imberti O, Remuzzi G. Evidence of the central role of the thymus in the induction of donor-specific unresponsiveness to a renal allograft. Transplantation 1992; 54: 943.
    • (1992) Transplantation , vol.54 , pp. 943
    • Perico, N.1    Rossini, M.2    Imberti, O.3    Remuzzi, G.4
  • 7
    • 0026100948 scopus 로고
    • Kidney graft survival in rats without immunosuppressants after intrathymic glomerular transplantation
    • Remuzzi G, Rossini M, Imberti O, Perico N. Kidney graft survival in rats without immunosuppressants after intrathymic glomerular transplantation. Lancet 1991; 337: 750.
    • (1991) Lancet , vol.337 , pp. 750
    • Remuzzi, G.1    Rossini, M.2    Imberti, O.3    Perico, N.4
  • 8
    • 0028059917 scopus 로고
    • Mechanisms of acquired thymic unresponsiveness to renal allografts
    • Sayegh MH, Perico N, Gallon L, et al. Mechanisms of acquired thymic unresponsiveness to renal allografts. Transplantation 1994; 58: 125.
    • (1994) Transplantation , vol.58 , pp. 125
    • Sayegh, M.H.1    Perico, N.2    Gallon, L.3
  • 9
    • 0027261280 scopus 로고
    • Intrathymic injection of donor alloantigens induces specific tolerance to cardiac allografts
    • Goss JA, Nakafusa Y, Yu S, Flye MW. Intrathymic injection of donor alloantigens induces specific tolerance to cardiac allografts. Transplantation 1993; 56: 166.
    • (1993) Transplantation , vol.56 , pp. 166
    • Goss, J.A.1    Nakafusa, Y.2    Yu, S.3    Flye, M.W.4
  • 10
    • 0027235704 scopus 로고
    • Induction of donor-specific unresponsiveness to rat cardiac allografts by intrathymic injection of UV-B-irradiated donor spleen cells
    • Oluwole SF, Chowdhury NC, Fawwaz RA. Induction of donor-specific unresponsiveness to rat cardiac allografts by intrathymic injection of UV-B-irradiated donor spleen cells. Transplantation 1993; 55: 1389.
    • (1993) Transplantation , vol.55 , pp. 1389
    • Oluwole, S.F.1    Chowdhury, N.C.2    Fawwaz, R.A.3
  • 11
    • 0027163189 scopus 로고
    • Induction of donor-specific unresponsiveness to rat cardiac allografts by pretreatment with intrathymic donor MHC class I antigens
    • Oluwole SF, Chowdhury NC, Fawwaz RA. Induction of donor-specific unresponsiveness to rat cardiac allografts by pretreatment with intrathymic donor MHC class I antigens. Transplantation 1993; 55: 1396.
    • (1993) Transplantation , vol.55 , pp. 1396
    • Oluwole, S.F.1    Chowdhury, N.C.2    Fawwaz, R.A.3
  • 12
    • 0026629861 scopus 로고
    • Induction of donor-specific tolerance to rat cardiac allografts by intrathymic inoculation of bone marrow
    • Odorico JS, Barker CF, Posselt AM, Naji A. Induction of donor-specific tolerance to rat cardiac allografts by intrathymic inoculation of bone marrow. Surgery 1992; 112: 370.
    • (1992) Surgery , vol.112 , pp. 370
    • Odorico, J.S.1    Barker, C.F.2    Posselt, A.M.3    Naji, A.4
  • 13
    • 0028822537 scopus 로고
    • Tolerance induction to cardiac allografts by simultaneous or sequential intrathymic inoculation of disparate alloantigens
    • Shimomura K, Hardy MA, Oluwole SF. Tolerance induction to cardiac allografts by simultaneous or sequential intrathymic inoculation of disparate alloantigens. Transplantation 1995; 60: 806.
    • (1995) Transplantation , vol.60 , pp. 806
    • Shimomura, K.1    Hardy, M.A.2    Oluwole, S.F.3
  • 14
    • 0027321053 scopus 로고
    • Induction of donor-specific tolerance to rat cardiac and small bowel allografts by intrathymic inoculation of donor T-cells
    • Chowdhury NC, Fawwaz RA, Oluwole SF. Induction of donor-specific tolerance to rat cardiac and small bowel allografts by intrathymic inoculation of donor T-cells. J Surg Res 1993; 54: 368.
    • (1993) J Surg Res , vol.54 , pp. 368
    • Chowdhury, N.C.1    Fawwaz, R.A.2    Oluwole, S.F.3
  • 15
    • 0027480565 scopus 로고
    • Prolonged survival of rat orthotopic liver allografts after intrathymic inoculation of donor-strain cells
    • Campos L, Alfrey EJ, Posselt AM, Odorico JS, Barker CF, Naji A. Prolonged survival of rat orthotopic liver allografts after intrathymic inoculation of donor-strain cells. Transplantation 1993; 55: 866.
    • (1993) Transplantation , vol.55 , pp. 866
    • Campos, L.1    Alfrey, E.J.2    Posselt, A.M.3    Odorico, J.S.4    Barker, C.F.5    Naji, A.6
  • 16
    • 0027092408 scopus 로고
    • Induction of specific unresponsiveness (tolerance) to skin allografts by intrathymic donor-specific splenocyte injection in antilymphocyte serum-treated mice
    • Ohzato H, Monaco AP. Induction of specific unresponsiveness (tolerance) to skin allografts by intrathymic donor-specific splenocyte injection in antilymphocyte serum-treated mice. Transplantation 1992; 54: 1090.
    • (1992) Transplantation , vol.54 , pp. 1090
    • Ohzato, H.1    Monaco, A.P.2
  • 17
    • 0027538290 scopus 로고
    • Deletion of donor-reactive T lymphocytes in adult mice after intrathymic inoculation with lymphoid cells
    • Markmann JF, Odorico JS, Bassiri H, Desai N, Kim JI, Barker CF. Deletion of donor-reactive T lymphocytes in adult mice after intrathymic inoculation with lymphoid cells. Transplantation 1993; 55: 871.
    • (1993) Transplantation , vol.55 , pp. 871
    • Markmann, J.F.1    Odorico, J.S.2    Bassiri, H.3    Desai, N.4    Kim, J.I.5    Barker, C.F.6
  • 18
    • 0014941813 scopus 로고
    • A theory of self-nonself discrimination
    • Bretscher P, Cohn M. A theory of self-nonself discrimination. Science 1970; 169: 1042.
    • (1970) Science , vol.169 , pp. 1042
    • Bretscher, P.1    Cohn, M.2
  • 19
    • 0024372111 scopus 로고
    • Acquisition of immunologic self-tolerance
    • Schwartz RH. Acquisition of immunologic self-tolerance. Cell 1989; 57: 1073.
    • (1989) Cell , vol.57 , pp. 1073
    • Schwartz, R.H.1
  • 20
    • 0028178873 scopus 로고
    • Signals and signs for lymphocyte responses
    • Janeway CA Jr, Bottomly K. Signals and signs for lymphocyte responses. Cell 1994; 76: 275.
    • (1994) Cell , vol.76 , pp. 275
    • Janeway C.A., Jr.1    Bottomly, K.2
  • 21
    • 0027403299 scopus 로고
    • The role of the CD28 receptor during T cell responses to antigen
    • Linsley PS, Ledbetter JA. The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol 1993; 11: 191.
    • (1993) Annu Rev Immunol , vol.11 , pp. 191
    • Linsley, P.S.1    Ledbetter, J.A.2
  • 22
    • 0028979466 scopus 로고
    • New perspectives of CD28-B7-mediated T cell costimulation
    • Bluestone JA. New perspectives of CD28-B7-mediated T cell costimulation. Immunity 1995; 2: 555.
    • (1995) Immunity , vol.2 , pp. 555
    • Bluestone, J.A.1
  • 23
    • 0029073090 scopus 로고
    • Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation
    • Thompson CB. Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation. Cell 1995; 81: 879.
    • (1995) Cell , vol.81 , pp. 879
    • Thompson, C.B.1
  • 24
    • 0026459468 scopus 로고
    • T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo
    • Turka LA, Linsley PS, Lin H, et al. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc Natl Acad Sci USA 1992; 89: 11102.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11102
    • Turka, L.A.1    Linsley, P.S.2    Lin, H.3
  • 25
    • 0027451441 scopus 로고
    • Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion
    • Lin H, Bolling SF, Linsley PS, et al. Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J Exp Med 1993; 178: 1801.
    • (1993) J Exp Med , vol.178 , pp. 1801
    • Lin, H.1    Bolling, S.F.2    Linsley, P.S.3
  • 26
    • 0030051268 scopus 로고    scopus 로고
    • Chronic cardiac rejection in the Lewis to F344 model: Blockade of CD 28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis
    • Russel ME, Hancock WW, Akalin E, et al. Chronic cardiac rejection in the Lewis to F344 model: blockade of CD 28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis. J Clin Invest 1996; 97: 833.
    • (1996) J Clin Invest , vol.97 , pp. 833
    • Russel, M.E.1    Hancock, W.W.2    Akalin, E.3
  • 27
    • 0029864501 scopus 로고    scopus 로고
    • Blockade of T-cell costimulation prevents development of experimental chronic allograft rejection
    • Azuma H, Chandraker A, Nadeau K, et al. Blockade of T-cell costimulation prevents development of experimental chronic allograft rejection. Proc Natl Acad Sci USA 1996; 93: 12439.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12439
    • Azuma, H.1    Chandraker, A.2    Nadeau, K.3
  • 28
    • 0028903939 scopus 로고
    • CD28-B7 blockade after alloantigen challenge in vivo inhibits Th1 cytokines but spares Th2
    • Sayegh MH, Akalin E, Hancock WW, et al. CD28-B7 blockade after alloantigen challenge in vivo inhibits Th1 cytokines but spares Th2. J Exp Med 1995; 181: 1869.
    • (1995) J Exp Med , vol.181 , pp. 1869
    • Sayegh, M.H.1    Akalin, E.2    Hancock, W.W.3
  • 30
    • 0028308543 scopus 로고
    • Successful heterotopic heart transplantation in the rat
    • Schmid C, Binder J, Heemann U, Tilney NL. Successful heterotopic heart transplantation in the rat. Microsurgery 1994; 15: 279.
    • (1994) Microsurgery , vol.15 , pp. 279
    • Schmid, C.1    Binder, J.2    Heemann, U.3    Tilney, N.L.4
  • 31
    • 0028337459 scopus 로고
    • Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function
    • Hathcock KS, Laszlo G, Pucillo C, Linsley P, Hodes RJ. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J Exp Med 1994; 180: 631.
    • (1994) J Exp Med , vol.180 , pp. 631
    • Hathcock, K.S.1    Laszlo, G.2    Pucillo, C.3    Linsley, P.4    Hodes, R.J.5
  • 32
    • 0027937702 scopus 로고
    • Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1
    • Peach RJ, Bajorath J, Brady W, et al. Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. J Exp Med 1994; 180: 2049.
    • (1994) J Exp Med , vol.180 , pp. 2049
    • Peach, R.J.1    Bajorath, J.2    Brady, W.3
  • 33
    • 0026035175 scopus 로고
    • Differential role of CD4+ cells in the sensitization and effector phases of accelerated graft rejection
    • Sablinski T, Sayegh MH, Hancock WW, et al. Differential role of CD4+ cells in the sensitization and effector phases of accelerated graft rejection. Transplantation 1991; 51: 226.
    • (1991) Transplantation , vol.51 , pp. 226
    • Sablinski, T.1    Sayegh, M.H.2    Hancock, W.W.3
  • 34
    • 0030240965 scopus 로고    scopus 로고
    • Induction of "infectious" tolerance to MHC-incompatible cardiac allografts in CD4 monoclonal antibody-treated sensitized rat recipients
    • Onodera K, Lehmann M, Akalin E, Volk HD, Sayegh MH, Kupiec-Weglinski JW. Induction of "infectious" tolerance to MHC-incompatible cardiac allografts in CD4 monoclonal antibody-treated sensitized rat recipients. J Immunol 1996; 157: 1944.
    • (1996) J Immunol , vol.157 , pp. 1944
    • Onodera, K.1    Lehmann, M.2    Akalin, E.3    Volk, H.D.4    Sayegh, M.H.5    Kupiec-Weglinski, J.W.6
  • 35
    • 0026066971 scopus 로고
    • IgM and IgG alloantibody production by splenocytes and deposition in rat renal allografts are decreased by donor-specific blood transfusion
    • Baldwin WM III, Rhoton K, Sanfilippo F. IgM and IgG alloantibody production by splenocytes and deposition in rat renal allografts are decreased by donor-specific blood transfusion. Transplantation 1991; 51: 481.
    • (1991) Transplantation , vol.51 , pp. 481
    • Baldwin W.M. III1    Rhoton, K.2    Sanfilippo, F.3
  • 36
    • 0028124625 scopus 로고
    • CTLA4Ig treatment ameliorates the lethality of murine graft-versus-host disease across major histocompatibility complex barriers
    • Wallace PM, Johnson JS, MacMaster JF, Kennedy KA, Gladstone P, Linsley PS. CTLA4Ig treatment ameliorates the lethality of murine graft-versus-host disease across major histocompatibility complex barriers. Transplantation 1994; 58: 602.
    • (1994) Transplantation , vol.58 , pp. 602
    • Wallace, P.M.1    Johnson, J.S.2    MacMaster, J.F.3    Kennedy, K.A.4    Gladstone, P.5    Linsley, P.S.6
  • 37
    • 0029060729 scopus 로고
    • Induction and reversal of long-lived specific unresponsiveness to a T-dependent antigen following CTLA4Ig treatment
    • Wallace PM, Rodgers JN, Leytze GM, Johnson JS, Linsley PS. Induction and reversal of long-lived specific unresponsiveness to a T-dependent antigen following CTLA4Ig treatment. J Immunol 1995; 154: 5885.
    • (1995) J Immunol , vol.154 , pp. 5885
    • Wallace, P.M.1    Rodgers, J.N.2    Leytze, G.M.3    Johnson, J.S.4    Linsley, P.S.5
  • 38
    • 0031203939 scopus 로고    scopus 로고
    • Do effector and memory T helper cells also need B7 ligand costimulatory signals?
    • Gause WC, Mitro V, Via C, Linsley P, Urban JF, Greenwald RJ. Do effector and memory T helper cells also need B7 ligand costimulatory signals? J Immunol 1997; 159: 1055.
    • (1997) J Immunol , vol.159 , pp. 1055
    • Gause, W.C.1    Mitro, V.2    Via, C.3    Linsley, P.4    Urban, J.F.5    Greenwald, R.J.6
  • 39
    • 0028209321 scopus 로고
    • Abrogation by rapamycin of accelerated rejection in sensitized rats by inhibition of alloantibody responses and selective suppression of intragraft mononuclear and endothelial cell activation, cytokine production, and cell adhesion
    • Schmidbauer G, Hancock WW, Wasowska B, Badger AM, Kupiec-Weglinski JW. Abrogation by rapamycin of accelerated rejection in sensitized rats by inhibition of alloantibody responses and selective suppression of intragraft mononuclear and endothelial cell activation, cytokine production, and cell adhesion. Transplantation 1994; 57: 933.
    • (1994) Transplantation , vol.57 , pp. 933
    • Schmidbauer, G.1    Hancock, W.W.2    Wasowska, B.3    Badger, A.M.4    Kupiec-Weglinski, J.W.5
  • 40
    • 0029967728 scopus 로고    scopus 로고
    • The effects of nondepleting CD4 targeted therapy in presensitized rat recipients of cardiac allografts
    • Binder J, Lehmann M, Graser E, et al. The effects of nondepleting CD4 targeted therapy in presensitized rat recipients of cardiac allografts. Transplantation 1996; 61: 804.
    • (1996) Transplantation , vol.61 , pp. 804
    • Binder, J.1    Lehmann, M.2    Graser, E.3
  • 41
    • 0028981462 scopus 로고
    • α/β-T cell receptor-directed therapy in rat cardiac allograft recipients
    • Heidecke CD, Hancock WW, Jakobs F, et al. α/β-T cell receptor-directed therapy in rat cardiac allograft recipients. Transplantation 1995; 59: 78.
    • (1995) Transplantation , vol.59 , pp. 78
    • Heidecke, C.D.1    Hancock, W.W.2    Jakobs, F.3
  • 42
    • 0029760962 scopus 로고    scopus 로고
    • Preventing allograft rejection with CTLA4Ig: Effect of donor-specific transfusion route or timing
    • Bolling SF, Lin H, Wie RQ, Turka LA. Preventing allograft rejection with CTLA4Ig: effect of donor-specific transfusion route or timing. J Heart Lung Transplant 1996; 15: 928.
    • (1996) J Heart Lung Transplant , vol.15 , pp. 928
    • Bolling, S.F.1    Lin, H.2    Wie, R.Q.3    Turka, L.A.4
  • 43
    • 0030474264 scopus 로고    scopus 로고
    • Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection
    • Hancock WW, Sayegh MH, Zheng XG, Peach R, Linsley PS, Turka LA. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci USA 1996; 93: 13967.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13967
    • Hancock, W.W.1    Sayegh, M.H.2    Zheng, X.G.3    Peach, R.4    Linsley, P.S.5    Turka, L.A.6
  • 44
    • 0029944669 scopus 로고    scopus 로고
    • CTLA4-Ig plus bone marrow induces long-term allograft survival and donor-specific unresponsiveness in the murine model
    • Pearson TC, Alexander DZ, Hendix R, et al. CTLA4-Ig plus bone marrow induces long-term allograft survival and donor-specific unresponsiveness in the murine model. Transplantation 1996; 61: 997.
    • (1996) Transplantation , vol.61 , pp. 997
    • Pearson, T.C.1    Alexander, D.Z.2    Hendix, R.3
  • 45
    • 0029100024 scopus 로고
    • Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibition by CTLA-4
    • Kearney ER, Walunas TL, Karr RW, et al. Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibition by CTLA-4. J Immunol 1995; 155: 1032.
    • (1995) J Immunol , vol.155 , pp. 1032
    • Kearney, E.R.1    Walunas, T.L.2    Karr, R.W.3
  • 47
    • 0026778697 scopus 로고
    • Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule
    • Linsley PS, Wallace PM, Johnson J, et al. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science 1992; 257: 792.
    • (1992) Science , vol.257 , pp. 792
    • Linsley, P.S.1    Wallace, P.M.2    Johnson, J.3
  • 48
    • 0025882079 scopus 로고
    • The blood transfusion effect: Experimental aspects
    • Bradley JA. The blood transfusion effect: experimental aspects. Immunol Lett 1991; 29: 127.
    • (1991) Immunol Lett , vol.29 , pp. 127
    • Bradley, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.