Lipocortin 1: A second messenger of glucocorticoid action in the hypothalamo-pituitary-adrenocortical axis

Molecular Medicine Today

Volumn 3, Issue 7, 1997, Pages 296-302

  Buckingham, Julia C ^a   Flower, Roderick J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

LIPOCORTIN 1;

HYDROCORTISONE RELEASE; HYPOPHYSIS ADRENAL SYSTEM; REVIEW; SECOND MESSENGER;

EID: 0031406852     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-4310(97)88908-3     Document Type: Review

References (39)

1. Munck, A., Guyre, P.M. and Holbrook, N.J. (1984) Physiological functions of glucocorticoids in stress and their relation to pharmacological actions, Endocr. Rev. 5, 25-44
2. Perretti, M. et al. (1989) The effect of adrenalectomy on interleukin-1 release in vitro and in vivo, Br. J. Pharmacol. 98, 1137-1142
3. Buckingham, J.C. (1996) Stress and the neuroendocrine axis: the pivotal role of glucocorticoids and lipocortin 1, Br. J. Pharmacol. 118, 1-19
4. Buckingham, J.C. et al. (1996) Activation of the HPA axis by immune insults: roles and interactions of cytokines, eicosanoids and glucocorticoids, Pharmacol. Biochem. Behav. 54, 285-298
5. Diamond, M.I. et al. (1990) Transcription factor interactions: selectors of positive or negative regulation from a single DNA element, Science 249, 1266-1272
6. Lew, W., Oppenheim, J.J. and Matsushima, K. (1988) Analysis of the suppression of IL-1α and IL-1β production in human peripheral blood mononuclear adherent cells by a glucocorticoid hormone, J. Immunol. 140, 1895-1902
7. Masferrer, J.L. et al. (1989) Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme, Proc. Natl. Acad. Sci. U. S. A. 89, 3917-3921
8. Moncada, S. and Palmer, R.M.J. (1991) Inhibition of the induction of nitric oxide synthase by glucocorticoids; yet another explanation of their anti-inflammatory effects, Trends Pharmacol. Sci. 12, 130-131
9. Raynal, P. and Pollard, H.B. (1994) Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins, Biochim. Biophys. Acta 1197, 63-93
10. Fava, R.A., McKanna, J. and Cohen, S. (1989) Lipocortin 1 (p35) is abundant in a restricted number of differentiated cell types in adult organs, J. Cell Physiol. 14, 284-293
11. Perretti, M. and Flower, R.J. (1996) Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation, Br. J. Pharmacol. 118, 605-610
12. Goulding, N.J. et al. (1990) Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone, Lancet 335, 1416-1418
13. Smith, T., Flower, R.J. and Buckingham, J.C. (1993) Lipocortins 1, 2 and 5 in the central nervous system and pituitary gland of the rat: elective induction by dexamethasone of lipocortin in the anterior pituitary gland, Mol. Neuropharmacol. 3, 45-55
14. Woods, M.D. et al. (1990) Localization of lipocortin 1 in rat hypothalamus and pituitary gland, Biochem. Soc. Trans. 18, 1236-1237
15. Browning, J.L. et al. (1990) Studies on the structural properties of lipocortin-1 and the regulation of its synthesis by steroids, in Cytokines and Lipocortins in Inflammation and Differentiation (Melli, M. and Parente, L., eds), pp. 27-45, Wiley-Liss
16. Croxtall, J.D. and Flower, R.J. (1992) Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line, Proc. Natl. Acad. Sci. U. S. A. 89, 3571-3575
17. Peers, S.H. et al. (1993) Glucocorticoid and nonglucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leukocytes in vivo, Br. J. Pharmacol. 108, 66-72
18. Flower, R.J. and Rothwell, N.J. (1994) Lipocortin 1: cellular mechanisms and clinical relevance. Trends Pharmacol. Sci. 15, 71-76
19. Vishwanath, B.S. et al. (1992) Adrenalectomy decreases lipocortin-1 messenger ribonucleic acid and tissue protein content in rats, Endocrinology 130, 585-591
20. Flower, R.J. (1988) Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids, Br. J. Pharmacol. 94, 987-1015
21. 2 by 'lipocortins' and calpactins. An effect of binding to substrate phospholipids, J. Biol. Chem. 262, 1698-1705
22. Croxtall, J.D. et al. (1995) Lipocortin 1 and the control of arachidonic acid release in cell signalling. Biochem. Pharmacol. 50, 465-474
23. Cirino, G. et al. (1989) Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test, Proc. Natl. Acad. Sci. U. S. A. 86, 3428-3432
24. Carey, F. et al. (1990) Lipocortin 1 fragment modifies pyrogenic actions of cytokines in rats. Am. J. Physiol. 259, 266-269
25. Davidson, J. et al. (1991) Antipyretic actions of human recombinant lipocortin-1, Br. J. Pharmacol. 102, 7-9
26. Perretti, M. and Flower, R.J. (1993) Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1, J. Immunol. 150, 992-999
27. Relton, J.K. et al. (1991) Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain, J. Exp. Med. 174, 305-310
28. Croxtall, J.D. and Flower, R.J. (1994) Antisense oligonucleotides to human lipocortin-1 inhibit glucocorticoid-induced inhibition of A549 cell growth and eicosanoid release, Biochem. Pharmacol. 48, 1729-1734
29. Goulding, N.J. et al (1989) Autoantibodies to recombinant lipocortin-1 in rheumatoid arthritis and systemic lupus erythematosus, Ann. Rheum. Dis. 48, 843-850
30. Loxley, H.D., Cowell, A-M., Flower, R.J. and Buckingham, J.C. (1993) Modulation of the hypothalamo-pituitary-adrenocortical responses to cytokines in the rat by lipocortin 1 and glucocorticoids: a role for lipocortin 1 in the feedback inhibition of CRF release? Neuroendocrinology 57, 801-814
31. Taylor, A.D. et al. (1993) Lipocortin 1 mediates an early inhibitory action of glucocorticoids on the secretion of ACTH by the rat anterior pituitary gland in vitro, Neuroendocrinology 58, 430-439
32. Taylor, A.D. et al. (1995) Immunoneutralization of lipocortin 1 reverses the acute inhibitory effects of dexamethasone on the hypothalamo-pituitary-adrenocortical responses to cytokines in the rat in vitro and in vivo, Neuroendocrinology 62, 19-31
33. Taylor, A.D. et al. (1995) Dexamethasone suppresses the release of prolactin from the rat anterior pituitary gland by lipocortin 1 dependent and independent mechanisms. Neuroendocrinology 62, 530-542
34. Taylor, A.D., Christian, H., Flower, R.J. and Buckingham, J.C. (1996) Antisense oligonucleotides to lipocortin 1 and ACTH secretion in vitro, J. Endocrinol. 151, P53
35. Christian, H. et al. (1995) Flow cytometric detection of lipocortin 1 binding sites on rat anterior pituitary cells, Pharmacol. Res. 31, 81P
36. Newman, S.P., Flower, R.J. and Croxtall, J.D. (1994) Dexamethasone suppression of IL-1β-induced cyclooxygenase 2 expression is not mediated by lipocortin 1 in A549 cells, Biochem. Biophys. Res. Commun. 200, 31-939
37. Wu, C-C. et al. (1995) Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc. Natl. Acad. Sci. U. S. A. 92, 3473-3477
38. Perretti, M. (1994) Lipocortin-derived peptides, Biochem. Pharmacol. 47, 931-938
39. Weng, X.W. et al. (1993) Crystal structure of human annexin-1 at 2.5 Å resolution, Protein Sci. 2, 448-158