Telomeres in the haemopoietic system

CIBA Foundation Symposia

Volumn , Issue 211, 1997, Pages 209-222

  Lansdorp, Peter M ^a,b   Poon, Steven ^a   Chavez, Elizabeth ^a   Dragowska, Visia ^a   Zijlmans, Mark ^a   Bryan, Tracy ^c   Reddel, Roger ^c   Egholm, Michael ^d   Bacchetti, Silvia ^e   Martens, Uwe ^a  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^d PERKINELMER INC   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

B LYMPHOCYTE; EPSTEIN BARR VIRUS; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; HEMATOPOIESIS; HUMAN; IMAGE PROCESSING; PHYSIOLOGY; REVIEW; TELOMERE; VIROLOGY; VIRUS CELL TRANSFORMATION;

B-LYMPHOCYTES; CELL TRANSFORMATION, VIRAL; HEMATOPOIESIS; HERPESVIRUS 4, HUMAN; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IN SITU HYBRIDIZATION, FLUORESCENCE; TELOMERASE; TELOMERE;

EID: 0031308375     PISSN: 03005208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Autexier C, Greider CW 1996 Telomerase and cancer: revisiting the telomere hypothesis. Trends Biochem Sci 21:387-391
2. Blackburn EH 1994 Telomeres: no end in sight. Cell 77:621-623
3. Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR 1995 Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 14:4240-4248
4. Chiu C-P, Dragowska W, Kim NW et al 1996 Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells 14:239-248
5. Counter CM, Botelho FM, Wang P, Harley CB, Bacchetti S 1994 Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J Virol 68:3410-3414
6. de Lange T 1995 Telomere dynamics and genome instability in human cancer. In: Blackburn EH, Greider CW (eds) Telomeres. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, p 265-293
7. Egholm M, Buchardt O, Christensen L et al 1993 PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen bonding rules. Nature 365:566-568
8. Grady DL, Ratliff RL, Robinson DL, McCanlies EC, Meyne J, Moyzis RK 1992 Highly conserved repetitive DNA sequences are present at human centromeres. Proc Natl Acad Sci USA 89:1695-1699
9. Hanish JP, Yanowitz JL, de Lange T 1994 Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci USA 91:8861-8865
10. Harley CB, Futcher AB, Greider CW 1990 Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460
11. Harley CB, Kim NW, Prowse KR et al 1994 Telomerase, cell immortality, and cancer. In: Blackburn EH, Greider CW (eds) Telomeres. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, p 307-315
12. Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC 1990 Telomere reduction in human colorectal carcinoma and with ageing. Nature 346:866-868
13. Hiyama K, Hirai Y, Kyoizumi S et al 1995 Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 155:3711-3715
14. Holt SE, Shay JW, Wright WE 1996 Refining the telomere-telomerase hypothesis of aging and cancer. Nat Biotech 14:834-837
15. Lansdorp PM 1995a Developmental changes in the function of hematopoietic stem cells. Exp Hematol 23:187-191
16. Lansdorp PM 1995b Telomere length and proliferation potential of hematopoietic stem cells. J Cell Sci 108:1-6
17. Lansdorp PM 1997 Self-renewal of stem cells. Biol Blood Marrow Transpl 3:171-178
18. Lansdorp PM, Dragowska W, Mayani H 1993 Ontogeny-related changes in proliferative potential of human hematopoietic cells. J Exp Med 178:787-791
19. Lansdorp PM, Verwoerd NP, van de Rijke FM et al 1996 Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 5:685-691
20. Martens UM, Zijlmans JM, Yui J, Poon SS, Chavez EA, Lansdorp PM 1996 Tissue-independent variation in telomere length on specific chromosomes. Blood 88:445a (abstr 1767)
21. Martens UM, Zijlmans JM, Poon SS, Dragowska 1997 Short telomeres on the P-arm of human chromosome 17, submitted
22. Murnane JP, Sabatier L, Marder BA, Morgan WF 1994 Telomere dynamics in an immortal human cell line. EMBO J 13:4953-4962
23. Pawliuk R, Eaves C, Humphries RK 1996 Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo. Blood 88:2852-2858
24. Potten CS, Loeffler M 1990 Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 10:1001-1020
25. Raap AK, Marijnen JGH, Vrolijk J, van der Ploeg M 1986 Denaturation, renaturation, and loss of DNA during in situ hybridization procedures. Cytometry 7:235-242
26. Slagboom PE, Droog S, Boomsma DI 1994 Genetic determination of telomere size in humans: a twin study of three age groups. Am J Hum Genet 55:876-882
27. Tkachuk DC, Pinkel D, Kuo W-L, Weier H-U, Gray JW 1991 Clinical applications of fluorescence in situ hybridization. Genet Anal Tech Appl 8:67-74
28. Trask B 1991 Fluorescence in situ hybridization. Application in cytogenetic and gene mapping. Trends Genet 7:149-154
29. Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB, Lansdorp PM 1994 Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc Natl Acad Sci USA 91:9857-9860
30. Weng N-P, Levine BL, June CH, Hodes RJ 1996 Regulated expression of telomerase activity in human T lymphocyte development and activation. J Exp Med 183:2471-2479
31. Yui J, Chiu C-P, Lansdorp PM 1997 Telomerase activity in candidate stem cells from fetal liver and adult bone marrow, submitted
32. Zakian VA 1995 Telomeres: beginning to understand the end. Science 270:1601-1607