Somatic Mutation in VH Complementarity-Determining Region 2 and Framework Region 2: Differential Effects on Antigen Binding and Ig Secretion

Journal of Immunology

Volumn 159, Issue 3, 1997, Pages 1293-1302

  Wiens, Gregory D ^a   Heldwein, Kurt A ^a   Stenzel Poore, Mary P ^a   Rittenberg, Marvin B ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN IDIOTYPE; MONOCLONAL ANTIBODY; MYELOMA PROTEIN TEPC15; PARAPROTEIN; PHOSPHORYLCHOLINE;

ANIMAL; ANTIBODY COMBINING SITE; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; MOUSE; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN IDIOTYPES; IMMUNOGLOBULIN VARIABLE REGION; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MYELOMA PROTEINS; PHOSPHORYLCHOLINE;

EID: 0031204378     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.159.3.1293     Document Type: Article

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