메뉴 건너뛰기




Volumn 84, Issue 7, 1997, Pages 753-756

Tumor suppressor p53 gene: A potential target for cancer therapy?;Le gene suppresseur de tumeur p53: Une cible possible pour la therapie anticancereuse ?

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; ANTINEOPLASTIC AGENT; E1B PROTEIN;

EID: 0031178899     PISSN: 00074551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (40)
  • 1
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene : Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, BennettWP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene : clues to cancer etiology and molecular pathogenesis. Cancer Res 1994 ; 54 : 4855-78.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 4
    • 0021616838 scopus 로고
    • UV irradiation stimulates levels of p53 cellular tumor antigen in non transformed mouse cells
    • Maltzman W, Czyzyk L. UV irradiation stimulates levels of p53 cellular tumor antigen in non transformed mouse cells. Mol Cell Biol 1984 ; 4 : 1689-94.
    • (1984) Mol Cell Biol , vol.4 , pp. 1689-1694
    • Maltzman, W.1    Czyzyk, L.2
  • 6
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 1991 ; 352 : 345-7.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 8
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
    • Fritsche M, Haessler C, Brandner G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 1993 ; 8 : 307-18.
    • (1993) Oncogene , vol.8 , pp. 307-318
    • Fritsche, M.1    Haessler, C.2    Brandner, G.3
  • 9
    • 0027109075 scopus 로고
    • P53, guardian of the genome
    • Lane D. p53, guardian of the genome. Nature 1992 ; 358 : 15-6.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.1
  • 12
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993 ; 74 : 957-67.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 16
    • 0027421045 scopus 로고
    • Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of burkitt lymphoma cell lines
    • O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I, Kohn KW. Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of burkitt lymphoma cell lines. Cancer Res 1993 ; 53 : 4776-80.
    • (1993) Cancer Res , vol.53 , pp. 4776-4780
    • O'Connor, P.M.1    Jackman, J.2    Jondle, D.3    Bhatia, K.4    Magrath, I.5    Kohn, K.W.6
  • 17
    • 0028944890 scopus 로고
    • Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines
    • Xia F, Wang X, Wang YH, Tsang NM, Yandell DW, Kelsey KT, Liber HL. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines. Cancer Res 1995 ; 55 : 12-5.
    • (1995) Cancer Res , vol.55 , pp. 12-15
    • Xia, F.1    Wang, X.2    Wang, Y.H.3    Tsang, N.M.4    Yandell, D.W.5    Kelsey, K.T.6    Liber, H.L.7
  • 18
    • 0029928561 scopus 로고    scopus 로고
    • Apoptotic death of tumor cells correlates with chemosensitivity, independent of p53 or Bcl-2
    • Wu GS, El-Deiry WS. Apoptotic death of tumor cells correlates with chemosensitivity, independent of p53 or Bcl-2. Clinical Cancer Research 1996 ; 2 : 623-33.
    • (1996) Clinical Cancer Research , vol.2 , pp. 623-633
    • Wu, G.S.1    El-Deiry, W.S.2
  • 20
    • 0030035584 scopus 로고    scopus 로고
    • P53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas
    • Benhattar J, Cerottini JP, Saraga E, Metthez G, Givel JC. p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas. Int J Cancer 1996 ; 69 : 190-2.
    • (1996) Int J Cancer , vol.69 , pp. 190-192
    • Benhattar, J.1    Cerottini, J.P.2    Saraga, E.3    Metthez, G.4    Givel, J.C.5
  • 23
    • 0029799803 scopus 로고    scopus 로고
    • Expression of p53 and apoptosis of tumor cells in locally advanced cervical carcinoma after cisplatin based neoadjuvant chemotherapy
    • Garzetti GG, Ciavattini A, Provinciali M, DiStefano G, Lucarini G, Goteri G, Biagini G. Expression of p53 and apoptosis of tumor cells in locally advanced cervical carcinoma after cisplatin based neoadjuvant chemotherapy. Anticancer Res 1996 ; 16 : 3229-34.
    • (1996) Anticancer Res , vol.16 , pp. 3229-3234
    • Garzetti, G.G.1    Ciavattini, A.2    Provinciali, M.3    DiStefano, G.4    Lucarini, G.5    Goteri, G.6    Biagini, G.7
  • 24
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins DS, Demers GW, Galloway DA. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res 1996 ; 56 : 892-8.
    • (1996) Cancer Res , vol.56 , pp. 892-898
    • Hawkins, D.S.1    Demers, G.W.2    Galloway, D.A.3
  • 25
    • 0029848257 scopus 로고    scopus 로고
    • Primary chemotherapy in breast invasive carcinoma : Predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi
    • Mac Grogan G, Mauriac L, Durand M, Bonichon F, Trojani M, de Mascarel I, Coindre JM. Primary chemotherapy in breast invasive carcinoma : predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi. Br J Cancer 1996 ; 74 : 1458-65.
    • (1996) Br J Cancer , vol.74 , pp. 1458-1465
    • Mac Grogan, G.1    Mauriac, L.2    Durand, M.3    Bonichon, F.4    Trojani, M.5    De Mascarel, I.6    Coindre, J.M.7
  • 27
    • 0028840535 scopus 로고
    • Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer
    • Rusch V, Klimstra D, Venkatraman E, Oliver J, Martini N, Gralla R, Kris M, Dmitrovsky E. Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer. Cancer Res 1995 ; 55 : 5038-42.
    • (1995) Cancer Res , vol.55 , pp. 5038-5042
    • Rusch, V.1    Klimstra, D.2    Venkatraman, E.3    Oliver, J.4    Martini, N.5    Gralla, R.6    Kris, M.7    Dmitrovsky, E.8
  • 28
    • 0028172868 scopus 로고
    • P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
    • Wattel E, Preudhomme C, Hecquet B, Vanrumbeke M, Quesnel B, Dervite I, Morel P, Fenaux P. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 1994 ; 84 : 3148-57.
    • (1994) Blood , vol.84 , pp. 3148-3157
    • Wattel, E.1    Preudhomme, C.2    Hecquet, B.3    Vanrumbeke, M.4    Quesnel, B.5    Dervite, I.6    Morel, P.7    Fenaux, P.8
  • 30
    • 0028231586 scopus 로고
    • Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
    • Fujiwara T, Grimm EA, Mukhopadhyay T, Zhang WW, Owenschaub LB, Roth JA. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res 1994 ; 54 : 2287-91.
    • (1994) Cancer Res , vol.54 , pp. 2287-2291
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Zhang, W.W.4    Owenschaub, L.B.5    Roth, J.A.6
  • 31
    • 0029832231 scopus 로고    scopus 로고
    • In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug
    • Blagosklonny MV, El-Deiry WS. In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug. Int J Cancer 1996 ; 67 : 386-92.
    • (1996) Int J Cancer , vol.67 , pp. 386-392
    • Blagosklonny, M.V.1    El-Deiry, W.S.2
  • 32
  • 33
    • 0029962567 scopus 로고    scopus 로고
    • Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells
    • Yang B, Eshleman JR, Berger NA, Markowitz SD. Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells. Clinical Cancer Research 1996 ; 2 : 1649-57.
    • (1996) Clinical Cancer Research , vol.2 , pp. 1649-1657
    • Yang, B.1    Eshleman, J.R.2    Berger, N.A.3    Markowitz, S.D.4
  • 34
    • 0027818396 scopus 로고
    • A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis
    • Fujiwara T, Grimm EA, Mukhopadhyay T, Cai DW, Owenschaub LB, Roth JA. A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis. Cancer Res 1993 ; 53 : 4129-33.
    • (1993) Cancer Res , vol.53 , pp. 4129-4133
    • Fujiwara, T.1    Grimm, E.A.2    Mukhopadhyay, T.3    Cai, D.W.4    Owenschaub, L.B.5    Roth, J.A.6
  • 35
    • 0030221787 scopus 로고    scopus 로고
    • The humoral response to the tumor-suppressor gene-product p53 in human cancer : Implications for diagnosis and therapy
    • Soussi T. The humoral response to the tumor-suppressor gene-product p53 in human cancer : implications for diagnosis and therapy. Immunol Today 1996 ; 17 : 354-6.
    • (1996) Immunol Today , vol.17 , pp. 354-356
    • Soussi, T.1
  • 37
    • 0029878034 scopus 로고    scopus 로고
    • Induction of cytotoxic T lymphocytes and antitumor immunity with DMA vaccines expressing single T cell epitopes
    • Ciernik IF, Berzofsky JA, Carbone DP. Induction of cytotoxic T lymphocytes and antitumor immunity with DMA vaccines expressing single T cell epitopes. J Immunol 1996 ; 156 : 2369-75.
    • (1996) J Immunol , vol.156 , pp. 2369-2375
    • Ciernik, I.F.1    Berzofsky, J.A.2    Carbone, D.P.3
  • 38
    • 0027444584 scopus 로고
    • Characterization of cytotoxic T-lymphocyte epitopes of a self-protein, p53, and a non-self-protein, influenza matrix - Relationship between major histocompatibility complex peptide binding affinity and immune responsiveness to peptides
    • Nijman HW, Houbiers JGA, Vanderburg SH, Vierboom MPM, Kenemans P, Kast WM, Melief CJM. Characterization of cytotoxic T-lymphocyte epitopes of a self-protein, p53, and a non-self-protein, influenza matrix - relationship between major histocompatibility complex peptide binding affinity and immune responsiveness to peptides. J Immunother 1993 ; 14 : 121-6.
    • (1993) J Immunother , vol.14 , pp. 121-126
    • Nijman, H.W.1    Houbiers, J.G.A.2    Vanderburg, S.H.3    Vierboom, M.P.M.4    Kenemans, P.5    Kast, W.M.6    Melief, C.J.M.7
  • 40
    • 0029978501 scopus 로고    scopus 로고
    • P53 as a target for cancer vaccines : Recombinant canarypox virus vectors expressing p53 protect mice against lethal tumor cell challenge
    • Roth J, Dittmer D, Rea D, Tartaglia J, Paoletti E, Levine AJ. p53 as a target for cancer vaccines : recombinant canarypox virus vectors expressing p53 protect mice against lethal tumor cell challenge. Proc Natl Acad Sci USA 1996 ; 93 : 4781-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4781-4786
    • Roth, J.1    Dittmer, D.2    Rea, D.3    Tartaglia, J.4    Paoletti, E.5    Levine, A.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.