Sequence and chromosomal mapping of the mouse homolog (Madh4) of the human DPC4/MADH4 gene

Mammalian Genome

Volumn 8, Issue 6, 1997, Pages 443-444

  Anna, Colleen H ^a   Devereux, Theodora R ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; MICROSATELLITE DNA; SMAD4 PROTEIN; SMAD4 PROTEIN, HUMAN; SMAD4 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; C3H MOUSE; C57BL MOUSE; CHROMOSOME MAP; CROSS BREEDING; DBA MOUSE; DINUCLEOTIDE REPEAT; DNA SEQUENCE; FEMALE; GENETICS; HUMAN; LUNG; MALE; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; MOUSE STRAIN; NORTHERN BLOTTING; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; CHROMOSOME MAPPING; CLONING, MOLECULAR; CROSSES, GENETIC; DINUCLEOTIDE REPEATS; DNA-BINDING PROTEINS; FEMALE; HUMANS; LUNG; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED STRAINS; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SMAD4 PROTEIN; TISSUE DISTRIBUTION; TRANS-ACTIVATORS;

ANIMALIA; RODENTIA;

EID: 0031153971     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900465     Document Type: Article

References (12)

1. Derynck R, Zhang Y (1996) Intracellular signalling: the Mad way to do it. Curr Biol 6, 1226-1229
2. Devereux TR, Wiseman RW, Kaplan N, Garren S, Foley JF, White CM, Anna C, Watson MA, Patel A, Jarchow S, Maronpot RR, Anderson MW (1994) Assignment of a locus for mouse lung tumor susceptibility to proximal chromosome 19. Mamm Genome 5, 749-755
3. Hahn SA, Hoque AT, Moskaluk CA, da-Costa LT, Schutte M, Rozenblum E, Seymour AB, Weinstein CL, Yeo CJ, Hruban RH, Kern SE (1996a) Homozygous deletion map at 18q21.1 in pancreatic cancer. Cancer Res 56, 490-494
4. Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da-Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE (1996b) DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353
5. Justice MJ, Gilbert DJ, Kinzler KW, Vogelstein B, Buchberg AM, Ceci JD, Matsuda Y, Chapman VM, Patriotis C, Makris A, Tsichlis PN, Jenkins NA, Copeland NG (1992) A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. Genomics 13, 1281-1288
6. Liu F, Hata A, Baker JC, Doody J, Carcamo J, Harland RM, Massague J (1996) A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623
7. Manly KF (1993) A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm Genome 4, 303-313
8. Nagatake M, Takagi Y, Osada H, Uchida K, Mitsudomi T, Saji S, Shimokata K, Takahashi T, Takahashi T (1996) Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers. Cancer Res 56, 2718-2720
9. Riggins GJ, Thiagalingam S, Rozenblum E, Weinstein CL, Kern SE, Hamilton SR, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B (1996) Mad-related genes in the human. Nature Genet 13, 347-349
10. Schutte M, Hruban RH, Hedrick L, Cho KR, Nadasdy GM, Weinstein CL, Bova GS, Isaacs WB, Cairns P, Nawroz H, Sidransky D, Casero R, Jr, Meltzer PS, Hahn SA, Kern SE (1996) DPC4 gene in various tumor types. Cancer Res 56, 2527-2530
11. Thiagalingam S, Lengauer C, Leach FS, Schutte M, Hahn SA, Overhauser J, Willson JK, Markowitz S, Hamilton SR, Kern SE, Kinzler KW, Vogelstein B (1996) Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature Genet 13, 343-346
12. Zhang Y, Feng Xin-Hua, Wu Rui-Yun, Derynck Rik (1996) Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 383, 168-172