Natural killer cell receptors specific for MHC class I molecules

Current Opinion in Immunology

Volumn 8, Issue 1, 1996, Pages 101-107

  Colonna, Marco ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; LECTIN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ALLELE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR CLONING; NATURAL KILLER CELL; SHORT SURVEY; TARGET CELL;

EID: 0029867236     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(96)80112-9     Document Type: Article

References (60)

1. Ljunggren HG, Karre K: In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today 1990, 11:237-244.
2. Karre K, Ljunggren HG, Piontek G, Kiessling R: Selective rejection of H·2-deficlent lymphoma variants suggests alternative immune defence strategy. Nature 1986, 319:675-678.
3. Bix M, Liao NS, Zijlstra M, Loring J, Jaenisch R, Raulet D: Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature 1991, 349:329-331.
4. - bone marrow in chimeric mice. Proc Natl Acad Sci USA 1991, 88:10332-10336.
5. Liao NS, Bix M, Zijlstra M, Jaenisch R, Raulet D: MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 1991, 253:199-202.
6. Storkus WJ, Alexander J, Payne JA, Dawson JR, Cresswell P: Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes. Proc Natl Acad Sci USA 1989, 86:2361-2364.
7. Shimizu Y, DeMars R: Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell-mediated lysis is inversely correlated with HLA class I antigen expression. Eur J Immunol 1989, 19:447-451.
8. Yokoyama WM: Recognition structures on natural killer cells. Curr Opin Immunol 1993, 5:67-73.
9. Cudkowicz G, Stimpfling JH: Induction of immunity and of unresponsiveness to parental marrow grafts in adult F1 hybrid mice. Nature 1964, 204:450-452.
10. Klein J: Biology of the Mouse Histocompatibility-2 Complex. New York: Springer-Verlag; 1975:511-517.
11. Yu YYL, Kumar V, Bennett M: Murine natural killer cells and marrow graft rejection. Annu Rev Immunol 1992, 10:189-213.
12. Ohlen C, Kling G, Hoglund P, Hansson M, Scangos G, Bieberich C, Jay G, Karre K: Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice. Science 1989, 246:666-668.
13. - lymphocytes in mixed lymphocyte culture. J Exp Med 1988, 168:2403-2408.
14. Colonna M, Spies T, Strominger JL, Ciccone E, Moretta A, Moretta L, Pende D, Viale O: Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene. Proc Natl Acad Sci USA 1992, 89:7983-7985.
15. Ciccone E, Pende D, Viale O, Than A, Di Donato C, Orengo AM, Biassoni R, Verdiani S, Amoroso A, Moretta A et al.: Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2). J Exp Med 1992, 176:963-971.
16. Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL: Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type. J Exp Med 1993, 178:1321-1336.
17. Lanier LL, Gumperz JE, Parham P, Melero I, Lopez-Botet M, Phillips JH: The NKB1 and HP-3E4 NK cells receptors are structurally distinct glycoprotelns and independently recognize polymorphic HLA-B and HLA-C molecules. J Immunol 1995, 154:3320-3327.
18. Vitale M, Sivori S, Pende D, Moretta L, Moretta A: Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells. Proc Natl Acad Sci USA 1995, 11:3536-3540.
19. Storkus WJ, Salter RD, Alexander J, Ward FE, Ruiz RE, Cresswell P, Dawson JR: Class I-induced resistance to natural killing: identification of nonpermissive residues in HLA-A2. Proc Natl Acad Sci USA 1991, 88:5989-5992.
20. Cella M, Longo A, Ferrara GB, Strominger JL, Colonna M: NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80. J Exp Med 1994, 180:1235-1242.
21. Gumperz JE, Litwin V, Phillips JH, Lanier LL, Parham P: The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med 1995, 181:1133-1144.
22. Biassoni R, Falco M, Cambiaggi A, Costa P, Verdiani S, Pende D, Conte R, Di Donato C, Parham P, Moretta L: Amino acid substitutions can influence the natural killer (NK)-medlated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by 'group 2' or 'group 1' NK clones. J Exp Med 1995, 182:605-609.
23. + IL-2-activated natural killer cells. Nature 1992, 358:66-70.
24. Karlhofer FM, Hunziker R, Reichlin A, Margulies DH, Yokoyama WM: Host MHC class I molecules modulate in vivo expression of a NK cell receptor. J Immunol 1994, 153:2407-2416.
25. Kane KP: Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules. J Exp Med 1994, 179:1011-1015.
26. Daniels BF, Karlhofer FM, Seaman WE, Yokoyama WM: A natural killer cell receptor specific for a major histocompatibility complex class I molecule. J Exp Med 1994, 180:687-692.
27. Yokoyama WM, Seaman WE: The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annu Rev Immunol 1993, 11:613-635.
28. d.
29. b class I molecules, and provides a molecular basis for the hybrid resistance phenomenon.
30. b bone marrow grafts. J Exp Med 1989, 170:191-202.
31. Karlhofer FM, Orihuela MM, Yokoyama WM: Ly-49-independent natural killer (NK) cell specificity revealed by NK cell clones derived from p53-deficient mice. J Exp Med 1995, 181:1785-1795. This work describes the first experimental system for the production of murine NK-cell clones.
32. + natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 1990, 171:695-714.
33. + natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J Exp Med 1990, 172:1589-1598.
34. Moretta A, Vitale M, Bottino C, Orengo AM, Morelli L, Augugliaro R, Barbaresi M, Ciccone E, Moretta L: P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J Exp Med 1993, 178:597-604.
35. Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL: NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med 1994, 180:537-543.
36. ••].
37. Wagtmann N, Biassoni R, Cantoni C, Verdiani S, Malnati MS, Vitale M, Bottino C, Moretta L, Moretta A, Long EO: Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 1995, 2:439-449. See annotation [38••].
38. ••], this paper describes the molecular cloning of the human NK cell receptors for HLA-B and HLA-C class I molecules.
39. Weiss A, Littman DR: Signal transduction by lymphocyte antigen receptors. Cell 1994, 76:263-274.
40. Wagtmann N, Rajagopalan S, Winter CC, Peruzzi M, Long EO: Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 1995, 3:801-809. Formal demonstration that human NK cell inhibitory receptors bind to HLA-C and HLA-B molecules and mediate inhibition of NK cell cytotoxicity.
41. Döring C, Colonna M: Human natural killer cell inhibitory receptors bind to HLA class I molecules. Eur J Immunol 1996, in press. This paper demonstrates direct binding of an NK inhibitory receptor to distinct HLA-C allotypes.
42. Malnati MS, Peruzzi M, Parker KC, Biddison WE, Ciccone E, Moretta A, Long EO: Peptide specificity in the recognition of MHC class I by natural killer cell clones. Science 1995, 267:1016-1018. Evidence that human NK-cell clones discriminate among peptides presented by HLA-B27.
43. Daniels BF, Nakamura MC, Rosen SD, Yokoyama WM, Seaman WE: Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain. Immunity 1994, 1:785-792.
44. Correa I, Raulet DH: Binding of diverse peptides to MHC class I molecules Inhibits target cell lysis by activated natural killer cells. Immunity 1995, 2:61-71.
45. Houchins JP, Yabe T, McSherry C, Bach FH: DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II Integral membrane proteins on human natural killer cells. J Exp Med 1991, 173:1017-1020.
46. Chang C, Rodriguez A, Carretero, M, Lopez-Botet M, Phillips JH, Lanier LL: Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Eur J Immunol 1995, 25:2433-2437. Molecular cloning of CD94.
47. Moretta A, Vitale M, Sivori S, Bottino C, Morelli L, Augugliaro R, Barbaresi M, Pende D, Ciccone E, Lopez Botet M et al.: Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med 1994, 180:545-555.
48. Perezvillar JJ, Melero I, Rodriguez A, Carretero M, Aramburu J, Sivori S, Orengo AM, Moretta A, Lopez-Bolet M: Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen. J Immunol 1995, 154:5779-5788.
49. Held W, Roland J, Raulet DH: Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells. Nature 1995, 376:355-358. Evidence that Ly-49A and Ly-49C allotypes are subjected to allelic exclusion.
50. Olsson MY, Karre K, Sentman CL: Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proc Natl Acad Sci USA 1995, 92:1649-1653. This work provides an experimental basis for the receptor-calibration hypothesis.
51. Kaufman DS, Schoon RA, Robertson MJ, Leibson PJ: Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc Natl Acad Sci USA 1995, 92:6484-6488. Characterization of the early signaling events that occur after NK-cell recognition of MHC class I molecules on target cells.
52. D'Ambrosio D, Hippen KL, Minskoff SA, Mellman I, Pani G, Simonovitch KA, Cambier JC: Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB. Science 1995, 268:293-297. Molecular mechanism of B-cell inhibition via FcγRII. Possible model for NK-cell inhibition.
53. Naper C, Vaage JT, Lambracht D, Lovik G, Butcher GW, Wonigeit K, Rolstad B: Alloreactive natural killer cells in the rat: complex genetics of major histocompatibility complex control. Eur J Immunol 1995, 25:1249-1256.
54. Moretta A, Sivori S, Vitale M, Pende D, Morelli L, Augugliaro R, Bottino C, Moretta L: Existence of both inhibitory (p58) and activa tory (p50) receptors for HLA-C molecules in human natural killer cells. J Exp Med 1995, 182:875-884. Identification of NK-cell receptors that are activated, rather than inhibited, by recognition of class I molecules.
55. Ferrini S, Cambiaggi A, Meazza R, Sforzini S, Marciano S, Mingari MC, Moretta L: T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function. Eur J Immunol 1994, 24:2294-2298.
56. Phillips JH, Gumperz JE, Parham P, Lanier LL: Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science 1995, 268:403-405. The HLA-B-specific receptor NKB1 is expressed on T cells and inhibits T-cell activation by superantigen-MHC complexes upon binding to HLA-B on the antigen-presenting cell.
57. Falk CS, Steinle A, Schendel DJ: Expression of HLA-C molecules confers target cell resistance to some non-major histocompatibility complex-restricted T cells in a manner analogous to allospecific natural killer cells. J Exp Med 1995, 182:1005-1018. Evidence that cytotoxicity of some T-cell clones is inhibited by the expression of HLA-C polymorphic determinants at positions 77-80 on target cells.
58. Smith HR, Karlhofer FM, Yokoyama WM: Ly-49 multigene family expressed by IL-2-activated NK cells. J Immunol 1994, 153:1068-1079.
59. Padlan EA, Helm BA: A modeling study of the α-subunit of human high-affinity receptor for immunoglobulin-E. Receptor 1992, 2:129-144.
60. Bernstein FC, Koetzle TF, Williams GJB, Meyer EF Jr, Brice MD, Rogers JR, Kennard O, Shimanouchi T, Tasumi M: The Protein Data Bank: a computer-based archival file for macromolecular structures. J Mol Biol 1977:535-542.