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Volumn 7, Issue 1, 1997, Pages 21-28

Cell fate determination in drosophila

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA; ECTODERM; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSE ORGAN; STEM CELL;

EID: 0031052831     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(97)80116-X     Document Type: Article
Times cited : (27)

References (66)
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    • of special interest. See annotation [52].
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    • of special interest. This paper and [51] present evidence that during the prophase of the neuroblasts, the asymmetric localization of Numb and of the product of the prospero gene is correlated with the position of one the two centrosomes and is thereby tightly linked to the axis of division.
    • Knoblich JA, Jan LY, Jan YN. Asymmetric segregation of Numb and Prospero during cell division. of special interest Nature. 377:1995;624-627 This paper and [51] present evidence that during the prophase of the neuroblasts, the asymmetric localization of Numb and of the product of the prospero gene is correlated with the position of one the two centrosomes and is thereby tightly linked to the axis of division.
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    • Role of inscuteable in orienting asymmetric cell divisions in Drosophila
    • of special interest. Shows that the product of the inscuteable gene is required for the localization of Numb and Prospero in dividing neuroblasts. This localization may depend on the control of spindle orientation, a process for which inscuteable is both necessary and sufficient.
    • Kraut R, Chia W, Jan LY, Jan YN, Knoblich JA. Role of inscuteable in orienting asymmetric cell divisions in Drosophila. of special interest Nature. 383:1996;50-55 Shows that the product of the inscuteable gene is required for the localization of Numb and Prospero in dividing neuroblasts. This localization may depend on the control of spindle orientation, a process for which inscuteable is both necessary and sufficient.
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    • of special interest. Analyzes the function of ramtrack (ttk) during sense organ lineages. Shows that ttk is instrumental in directing the cells to a non-neural fate and that it is expressed in cells with non-neural fates. Also demonstrates that ttk acts downstream of numb.
    • Guo M, Bier E, Jan LY, Jan YN. tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. of special interest Neuron. 14:1995;913-925 Analyzes the function of ramtrack (ttk) during sense organ lineages. Shows that ttk is instrumental in directing the cells to a non-neural fate and that it is expressed in cells with non-neural fates. Also demonstrates that ttk acts downstream of numb.
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    • of special interest. An excellent clonal analysis of the function of Notch during wing margin neurogenesis, showing convincingly that Notch is required to set up the expression of wingless but is not involved in the mechanism by which wingless, subsequently, activates the expression of the genes of the AS-C.
    • Rulifson EJ, Blair SS. Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. of special interest Development. 121:1995;2813-2824 An excellent clonal analysis of the function of Notch during wing margin neurogenesis, showing convincingly that Notch is required to set up the expression of wingless but is not involved in the mechanism by which wingless, subsequently, activates the expression of the genes of the AS-C.
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    • Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation
    • of special interest. Three recent papers [61-63] show that the expression of wingless at the dorsoventral (D/V) boundary depends on two different signals acting through the same receptor, Notch. One ligand, Serrate, is produced by the dorsal cells and signals ventral cells abutting the D/V compartment boundary; these, in turn, produce another ligand, Delta, to signal the dorsal cells abutting the same boundary. As a result of this mutual induction, the two rows of signalled cells flanking the D/V boundary express the wing margin organizer wingless.
    • Doherty D, Feger G, Younger-Shepherd S, Jan LY, Jan YN. Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. of special interest Genes Dev. 10:1996;421-435 Three recent papers [61-63] show that the expression of wingless at the dorsoventral (D/V) boundary depends on two different signals acting through the same receptor, Notch. One ligand, Serrate, is produced by the dorsal cells and signals ventral cells abutting the D/V compartment boundary; these, in turn, produce another ligand, Delta, to signal the dorsal cells abutting the same boundary. As a result of this mutual induction, the two rows of signalled cells flanking the D/V boundary express the wing margin organizer wingless.
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    • Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis
    • of outstanding interest. Shows that, depending on the orientation of the division axis, precursor cells in the mouse cortex either divide symmetrically (and produce two new precursors) or divide asymmetrically. In the asymmetric divisions, mouse Notch (M-Notch1) segregates in one of the two daughter cells, which will then migrate and differentiates as a neuron.
    • Chen A, McConnell SK. Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis. of outstanding interest Cell. 82:1995;631-641 Shows that, depending on the orientation of the division axis, precursor cells in the mouse cortex either divide symmetrically (and produce two new precursors) or divide asymmetrically. In the asymmetric divisions, mouse Notch (M-Notch1) segregates in one of the two daughter cells, which will then migrate and differentiates as a neuron.
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    • Chen, A.1    McConnell, S.K.2
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    • An inductive interaction in 4-cells stage C. elegans embryos involves APX-1 expression in the signalling cell
    • Mickey K, Mello CC, Montgomery MK, Fire A, Priess JR. An inductive interaction in 4-cells stage C. elegans embryos involves APX-1 expression in the signalling cell. Development. 122:1996;1791-1798.
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    • Mickey, K.1    Mello, C.C.2    Montgomery, M.K.3    Fire, A.4    Priess, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.