Glial lineages and myelination in the central nervous system

Journal of Anatomy

Volumn 190, Issue 2, 1997, Pages 161-200

  Compston, Alastair ^a   Zajicek, John ^b   Sussman, Jon ^f   Webb, Anna ^f   Hall, Gillian ^f   Muir, David ^c   Shaw, Christopher ^d   Wood, Andrew ^e   Scolding, Neil ^f  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b DERRIFORD HOSPITAL   (United Kingdom)

^c BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e PFIZER INC   (United States)

^f NONE

Author keywords

Astrocytes; Development; Microglia; Myelin; Oligodendrocytes; Repair

Indexed keywords

CYTOKINE; GROWTH FACTOR; MYELIN; NERVE GROWTH FACTOR;

ANIMAL CELL; ASTROCYTE; BLOOD BRAIN BARRIER; CELL DIFFERENTIATION; CELL LINEAGE; CENTRAL NERVOUS SYSTEM; GLIA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MICROGLIA; MYELIN SHEATH; MYELINATION; NERVOUS SYSTEM DEVELOPMENT; NEUROBIOLOGY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REMYELINIZATION; REVIEW; STEM CELL;

ADULT; ANIMALS; CELL LINEAGE; CENTRAL NERVOUS SYSTEM; HUMANS; MYELIN SHEATH; NERVE REGENERATION; NEUROGLIA; RATS;

ANIMALIA;

EID: 0031040747     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0021878296001707     Document Type: Review

References (310)

1. ACHESON A, BARKER PA, ALDERSON RF, MILLER FD, MURPHY RA (1991) Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF. Neuron 7, 265-273.
2. ACHESON A, CONOVER JC, FANDL JP, DECHIARA TM, RUSSELL M, THADANI A et al. (1995) A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 374, 450-453.
3. AJEMIAN A, NESS R, DAVID S (1994) Tenascin in the injured rat optic nerve and in non-neuronal cells in vitro : potential role in neural repair. Journal of Comparative Neurology 340, 233-242.
4. ALMAZAN G, MCKAY R (1992) An oligodendrocyte precursor cell line from rat optic nerve. Brain Research 579, 234-245.
5. ALOISI F, GIAMPAOLO A, RUSSO G, PESCHLE C, LEVI G (1992) Developmental appearance, antigenic profile and proliferation of glial cells of the human embryonic spinal cord. Glia 5, 171-181.
6. ALTHAUS HH, KLOPPNER S, SCHMIDT-SCHULTZ T, SCHWARTZ P (1992) Nerve growth factor induces proliferation and enhances fiber regeneration in oligodendrocytes isolated from adult pig brain. Neuroscience Letters 135, 219-223.
7. ANDRIEZEN WL (1893) The neuroglial elements of the brain. British Medical Journal ii : 227-230.
8. APPEL K, HONNEGGER P, GEBICKE-HAERTER PJ (1995) Expression of interleukin-3 and tumour necrosis factor-β mRNAs in cultured microglia. Journal of Neuroimmunology 60, 83-91.
9. ARMSTRONG R, FRIEDRICH VL, HOLMES KV, DUBOIS-DALCQ M (1989) In vitro analysis of the oligodendrocyte lineage in mice during demyelination and remyelination. Journal of Cell Biology 111, 1183-1195.
10. ARMSTRONG RC, DORN HH, KUFTA CV, FRIEDMAN E, DUBOIS DALCQ M (1992) Pre-oligodendrocytes from adult human CNS. Journal of Neuroscience 12, 1538-1547.
11. AVELLANA-ADALID V, LACHAPELLE G, ROUGON A, BARON VAN EVERCOOREN A (1994) Expansion of rat O-2A glial progenitors into proliferative oligospheres that retain their myelinating capacity after transplantation into the shiverer newborn mouse brain. Society for Neuroscience Abstracts 20, 885.
12. BANSAL R, PFEIFFER SE (1992) Novel stage in the oligodendrocyte lineage defined by reactivity of progenitors with R-mAb prior to O1 anti-galactocerebroside. Journal of Neuroscience Research 32, 309-316.
13. BANTLOW CE, HEUMANN R, SCHWAB M, THOENEN H (1987) Cellular localisation of nerve growth factor synthesis by in situ hybridisation. European Molecular Biology Journal 6, 891-899.
14. BARON-VAN EVERCOOREN A, AVELLANA-ADALID V, BEN YOUNGES-CHENNOUFI A, GANSMULLER A, NAIT-OUMESMAR B, VIGNAIS L (1996) Cell-cell interactions during the migration of myelin-forming cells transplanted in the demyelinated spinal cord. Glia 16, 147-164.
15. BARNETT SC, FRANKLIN RJ, BLAKEMORE WF (1993) In vitro and in vivo analysis of a rat bipotential O-2A progenitor cell line containing the temperature sensitive mutant gene of the SV 40 large T antigen. European Journal of Neuroscience 5, 1247-1260.
16. BARRES BA, HART IK, COLES HSR, BURNE JF, VOYVODIC JT, RICHARDSON WD et al. (1992) Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70, 31-46.
17. BARRES BA, RAFF MC (1993) Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons. Nature 361, 258-260.
18. BARRES BA, RAFF MC (1994) Control of oligodendrocyte number in the developing rat optic nerve. Neuron 12, 935-942.
19. BARRES BA, SCHMID R, SENDTNER M, RAFF MC (1993) Multiple extracellular signals are required for long-term oligodendrpcyte survival. Development 118, 283-295.
20. BARRES BA, RAFF MC, GAESE F, BARTKE I, DESCHANT G, BARDE YA (1994) A crucial role for neurotrophin-3 in oligodendrocyte development. Nature 367, 371-375.
21. BARTSCH U, PESHAVA P, RAFF M, SCHACHNER M (1993) Expression of janusin (J1-160/180) in the retina and optic nerve of the developing and adult mouse. Glia 9, 57-69.
22. BARTSCH U, BANDTLOW CE, SCHNELL L, BARTSCH S, SPILLMANN AA, RUBIN BP et al. (1995) Lack of evidence that myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS. Neuron 15, 1375-1381
23. BEHAR T, MCMORRIS FA, NOVOTNY EA, BARKER JL, DUBOIS-DALCQ M (1988) Growth and differentiation properties of O-2A progenitor cells purified from rat cerebral hemispheres. Journal of Neuroscience Research 21, 168-180.
24. BERRY M, HALL S, REES L, CARLISLE J, WYSE JPH (1992) Regeneration of axons in the optic nerve of the adult Browman-Wyse (BW) rat. Journal of Neurocytology 21, 426-448.
25. BLACK JA, FRIEDMAN B, WAXMAN SG, ELMER LW, ANGELIDES KJ (1989) Sodium channels in astrocytes of rat optic nerve in situ: immuno-electron microscopic studies. Glia 2, 353-369.
26. BLACK JA, SONTHEIMER H, WAXMAN SG (1993) Spinal cord astrocytes in vitro: phenotypic diversity and sodium channel immunoreactivity. Glia 7, 272-285.
27. BLAKEMORE WF (1973) Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone. Journal of the Neurological Sciences 20, 63-72.
28. BLAKEMORE WF (1974) Remyelination of the superior cerebellar peduncle in old mice following demyelination induced by cuprizone. Journal of the Neurological Sciences 22, 121-126.
29. BLAKEMORE WF (1977) Remyelination of CNS axons by Schwann cells transplanted from the rat sciatic nerve. Nature 266, 68-69.
30. BLAKEMORE WF, CRANG AJ, CURTIS R (1986) The interaction of Schwann cells with CNS axons in regions containing normal astrocytes. Acta Neuropathologica 71, 295-300.
31. BLAKEMORE WF, CRANG AJ (1989) The relationship between type 1 astrocytes, Schwann cells and oligodendrocytes following transplantation of glial cell cultures into demyelinating lesions in the adult rat spinal cord. Journal of Neurocytology 18, 519-528.
32. BO L, MORK S, KONG PA, NYLAND H, PARDO CA, TRAPP BD (1994) Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. Journal of Neuroimmunology 51, 135-146.
33. BOGLER O, WREN D, BARNETT SC, LAND M, NOBLE M (1990) Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type 2 astrocyte (O-2A) progenitor cells. Procedings of the National Academy of Sciences of the USA 87, 6368-6372.
34. BRADBURY M (1979) The Concept of the Blood-Brain Barrier. New York: John Wiley.
35. BREGMAN BS, KUNKEL-BAGDEN E, SCHNELL L, NING DAI H, GAO D, SCHWAB ME (1995) Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378, 498-501.
36. BROCKES JP (1984) Mitogenic growth factors and nerve dependence of limb regeneration. Science 225: 1280-1287.
37. BRIGHTMAN M (1991) Implication of astroglia in the blood-brain barrier. Annals of the New York Academy of Sciences 633, 343-347.
38. BRODIE C, GOLDREICH N (1994) Interleukin-4 modulates the proliferation and differentiation of glial cells. Journal of Neuroimmunology 55, 91-97.
39. BUNGE MB, BUNGE RP, RIS H (1961) Ultrastructural study of, remyelination in an experimental lesion in adult cat spinal cord. Journal of Biophysical and Biochemical Cytology 10, 67-94.
40. BUTT AM, RANSOM BR (1989) Visualisation of oligodendrocytes and astrocytes in the intact rat optic nerve by intracellular injection of lucifer yellow and horseradish peroxidase. Glia 2, 470-475.
41. CAJAL SR (1913) Contribution al conocmiento de la neuroglia del cerebra humano. Trabajos del Laboratorio de Investigations Biologicas 11, 255-315.
42. CALEY D, MAXWELL DS (1968) An electron microscopy study of the neuroglia during postnatal development of the rat cerebellum. Journal of Comparative Neurology 133: 45-70.
43. CAMERON RS, RAKIC P (1991) Glial cell lineage in the cerebral cortex: a review and synthesiis. Glia 4, 124-137.
44. CARONI P, SCHWAB ME (1988) Antibody against myelin associated inhibitor of neurite growth neutralises non-permissive substrate properties of CNS white matter. Neuron 1, 85-96.
45. CARROLL WM, JENNINGS AR, MASTAGLIA FL (1990) The origin of remyelinating oligodendrocytes in antiserum-mediated demyelinative optic neuropathy. Brain 113, 953-973.
46. CARROLL WM, JENNINGS AR (1994) Early recruitment of oligodendrocyte precursors in CNS demyelination. Brain 117, 563-578.
47. CHAO CC, MOLITOR TW, HU S (1993) Neuroprotective role of IL-4 against activated microglia. Journal of Immunology 151, 1473-1481.
48. CHEN SJ, DE VRIES GH (1989) The mitogenic effect of the axolemma-enriched fraction on cultured oligodendrocytes. Journal of Neurochemistry 52, 325.
49. CLARK P, CONNOLLY P, CURTIS ASG, DOW JAT, WILKINSON CDW (1990) Topographical control of cell behaviour: II. Multiple grooved substrata. Development 99, 439-448.
50. COLELLO RJ, POTT U, SCHWAB ME (1994) The role of oligodendrocytes and myelin on axon maturation in the developing rat retinofugal pathway. Journal of Neuroscience 14, 2594-2605.
51. DAVID S, MILLER RH, PATEL R, RAFF MC (1984) Effects of neonatal transection on glial cell development in the rat optic nerve: evidence that the oligodendrocyte-type 2 astrocyte cell lineage depends on axons for its survival. Journal of Neurocytology 13, 961-974.
52. DAVIS AA, TEMPLE S (1994) A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature 372, 263-266.
53. DUBOIS-DALCQ M (1995) Regeneration of oligodendrocytes and myelin. Trends in Neurosciences 18, 289-291.
54. DUBOIS-DALCQ M, BEHAR T, HUDSON L, LAZZARINI RA (1986) Emergence of three myelin proteins in oligodendrocytes cultured without neurones. Journal of Cell Biology 102, 384-392.
55. DUNCAN ID, ARCHER DR, HAMMANG JP (1993) EGF-responsive neural stem cells from rat and mouse brain are capable of differentiating into oligodendrocytes and of forming myelin following transplantation into the myelin deficient rat. Society for Neuroscience Abstracts 19: 689.
56. DUTLEY F, SCHWAB ME (1991) Neurons and astrocytes influence the development of purified O-2A progenitor cells. Glia 4, 559-571.
57. EDDLESTON M, MUCKE L (1993) Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 54, 15-36.
58. EISENBARTH GS, WALSH FS, NIRENBERG M (1979) Monoclonal antibody to a plasma membrane antigen of neurons. Proceedings of the National Academy of Sciences of the USA 76, 4913-4917.
59. EITAN S, ZISLING R, COHEN A, BELKIN M, HIRSCHBERG DL, LOTAN M et al. (1992) Identification of an interleukin 2-like substance as a factor cytotoxic to oligodendrocytes and associated with central nervous system regeneration. Proceedings of the National Academy of Sciences of the USA 89, 5442-5446.
60. EITAN S, SCHWARTZ M (1993) A transglutaminase that converts interleukin-2 into a factor cytotoxic to oligodendrocytes. Science 261, 106-108.
61. ELDE R, CAO Y, CINTRA A, BRELJE TC, PELTO-HUIKKO M, JUNTILLA T et al. (1991) Prominent expression of acidic fibroblast growth factor in motor and sensory neurons. Neuron 7, 349-364.
62. ENGEL U, WOLSWIJK G (1996) Oligodendrocyte-type-2 astrocyte . (0-2A) progenitor cells derived from adult-rat spinal-cord - in vitro characteristics and response to PDGF, bFGF and NT3. Glia 16, 16-26
63. FAWCETT JW, HOUSDEN E (1990) The effects of proteases inhibitors on axon growth through astrocytes. Development 109, 59-66.
64. FAWCETT JW, HOUSDEN E, SMITH-THOMAS L, MYER RL (1989a) The growth of axons in 3 dimensional astrocyte cultures. Developmental Biology 135, 449-458.
65. FAWCETT JW, ROKOS J, BAKST I (1989b) Oligodendrocytes repel axons and cause axonal growth cone collapse. Journal of Cell Science 92, 93-100.
66. FELTS PA, SMITH KJ (1992) Conduction properties of central nerve fibres remyelinated by Schwann cells. Brain Research 574, 178-192.
67. FERRARA N, OUSLEY F, GOSPODARAWICZ D (1988) Bovine brain astrocytes express fibroblast growth factor, a neurotrophic and angiogenic mitogen. Brain Research 462, 223-232.
68. FISHELL G, MASON CA, HATTEN ME (1993) Dispersion of neural progenitors within the germinal zones of the forebrain. Nature 362, 636-638.
69. FFRENCH-CONSTANT C, RAFF MC (1986) Proliferating bipotential glial progenitor cells in adult rat optic nerve. Nature 319, 499-502.
70. FORD AL, GOODSALL AL, HICKEY WF, SEDGWICK ID (1995) Normal adult microglia separated from other central nervous system macrophages by flow cytometry sorting. Journal of Immunology 154, 4309-4321.
71. FRANKLIN RJM, CRANG AJ, BLAKEMORE WF (1991) Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord. Journal of Neurocytology 20, 420-430.
72. FRANKLIN RJM, BLAKEMORE WF (1995) Glial-cell transplantation and plasticity in the O-2A lineage-implications for CNS repair. Trends in Neurosciences 18, 151-156.
73. FRANKLIN RJM, BAYLEY SA, MILNER R, FFRENCH-CONSTANT C, BLAKEMORE WF (1995) Differentiation of the O-2A progenitor line CG-4 into oligodendrocytes and astrocytes following transplantation into glia deficient areas of CNS white matter. Glia 13, 39-44.
74. FRANKLIN RJM, BAYLEY SA, BLAKEMORE WF (1996) Transplanted CG-4 cells (an oligodendrocyte progenitor cell line) survive, migrate and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cord. Experimental Neurology 137, 263-276.
75. FREI K, BODMER S, SCHWERDEL C, FONTANA A (1985) Astrocytes of the brain synthesize interleukin 3-like factors. Journal of Immunology 135, 4044-4047.
76. FREI K, SIEPL C, GROSCURTH P, BODMER S, SCHWERDEL C, FONTANA A (1987) Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. European Journal of Immunology 17, 1271-1278.
77. FREI K, MALPIERO UV, LEIST TP, ZINKERNAGEL RM, SCHWAB ME, FONTANA A (1989) On the cellular source and functions of interleukin-6 produced in the central nervous system in viral disease. European Journal of Immunology 19, 689-694.
78. FREI K, LINS H, SCHWERDEL C, FONTANA A (1994) Antigen presentation in the central nervous system: the inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed. Journal of Immunology 152, 2720-2728.
79. FREIDIN M, BENNETT MVL, KESSLER JA (1992) Cultured sympathetic neurons synthesize and release the cytokine interleukin 1 beta. Procedings of the National Academy of Sciences of the USA 89, 10440-10443.
80. FUGITA S (1963) The matrix cell and cytogenesis in the developing central nervous system. Journal of Comparative Neurology 120, 37-42.
81. FUGITA S (1965) An autoradiographic study on the origin and fate of the sub-pial glioblast in the embryonic chick spinal cord. Journal of Comparative Neurology 124, 51-60.
82. FULTON BP, BURNE JF, RAFF MC (1992) Visualisation of O-2A progenitor cells in developing and adult rat optic nerve by quisqualate-stimulated cobalt uptake. Journal of Neuroscience 12, 4816-4833.
83. GALILEO DS, GRAY GE, OWENS GC (1990) Neurons and glia ariser from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies. Proceedings of the National Academy of Sciences of the USA 87, 458-462.
84. -) under different mitogenic control. Neuron 5, 615-625.
85. GARD AL, BURRELL MR, PFEIFFER SE, RUDGE JS, WILLIAMS WC II (1995A). Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein. Development 121, 2187-2197
86. - and response to cytokines using signal transducer LIFR beta. Developmental Biology 167, 596-608
87. GEBICKE-HAERTER PJ, APPEL K, TAYLOR GD, SCHOBERT A, RICH IN, NORTHOFF H et al. (1994) Rat microglial interleukin-3. Journal of Neuroimmunology 50, 203-214.
88. GEHRMANN J (1995) Colony-stimulating factors regulate programmed cell death of rat microglia/brain macrophages in vitro. Journal of Neuroimmunology 63, 55-61.
89. GEHRMANN J, BANATI RB, KREUTZBERG GW (1993) Microglia in the immune surveillance of the brain : human microglia constitutively express HLA-DR molecules. Journal of Neuroimmunology 48, 189-198.
90. GLEDHILL RF, HARRISON BM, MCDONALD WI (1973) Pattern of remyelination in the CNS. Nature 244, 443-444.
91. GODFRAIND C, FRIEDRICH VL, HOLMES KV, DUBOIS-DALCQ M (1989) In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice. Journal of Cell Biology 109, 2405-2416.
92. GOGATE N, VERMA L, MIN ZHAU J, MILWARD E, RUSTEN R, O'CONNOR M et al. (1994) Plasticity in the adult human oligodendrocyte lineage. Journal of Neuroscience 14, 4571-4587.
93. GOLDMAN JE, HIRANO M, YU RK, SEYFRIED TN (1984) GD3 ganglioside is a glycolipid characteristic of immature neuroectodermal cells. Journal of Neuroimmunology 7, 179-192.
94. GOLDMAN JE, VAYSSE PJ-J (1991) Tracing glial cell lineages in the mammalian forebrain. Glia 4, 149-156.
95. GRAY PTA, RITCHIE JM (1985) Ion channels in Schwann and glial cells. Trends in Neurosciences 8, 411-415.
96. GRINSPAN JB, STERN JL, PUSTILNIK SM, PLEASURE D (1990) Cerebral white matter contains PDGF-responsive precursors to O-2A cells. Journal of Neuroscience 10, 1866-1873.
97. GRINSPAN JB, STERN JL, FRANCESCHINI B, PLEASURE D (1993) Trophic effects of basic fibroblast growth factor (bFGF) on differentiated oligodendroglia : a mechanism for regeneration of the oligodendroglial lineage. Journal of Neuroscience Research 36, 672-680.
98. GRITTI A, COVA L, PARATI EA, GALLI R, VESCOVI AL (1995) Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS. Neuroscience Letters 185, 151-154.
99. GROVES AK, ENTWISTLE A, JAT PS, NOBLE M (1993a) The characterisation of astrocyte cell lines that display properties of glial scar tissue. Developmental Biology 159, 87-104.
100. GROVES AK, BARNETT SC, FRANKLIN RJM, CRANG AJ, MAYER M, BLAKEMORE WF et al. (1993b) Repair of demyelinated lesions by transplantation of purified O-2A progenitor cells. Nature 362, 453-455.
101. GUILIAN D, BAKER TJ, SHIN LCN, LACHMAN LB (1986) Interleukin-1 of the central nervous system is produced by ameboid microglia. Journal of Experimental Medicine 164, 594-604.
102. GUILIAN D, JOHNSON B, KREBS JF, TAPSCOTT MJ, HONDA S (1991) A growth factor from neuronal cell lines stimulates myelin protein synthesis in mammalian brain. Journal of Neuroscience 11, 327-336.
103. GUMPEL M, BAUMANN N, RAOUL M, JACQUE C (1983) Survival and differentiation of oligodendrocytes from neural tissue transplanted into new-born mouse brain. Neuroscience Letters 37, 307-311.
104. GUMPEL M, LACHAPELLE F, GANSMULLER A, BAULAC M, BARONVAN EVERCOOREN A, BAUMANN N (1987) Transplantation of human embryonic oligodendrocytes into shiverer brain. Annals of the New York Academy of Sciences 495, 71-85.
105. HAGG T, VARON S, LOUIS JC (1993) Ciliary neurotrophic factor (CNTF) promotes low-affinity nerve growth factor receptor and CD4 expression by rat CNS microglia. Journal of Neuroimmunology 48, 177-188.
106. HALL G, WING MG, COMPSTON DAS, SCOLDING NJ (1996) Beta-interferon regulates the immunoregulatory activity of neonatal rodent microglia. Journal of Neuroimmunology, in press.
107. HAO C, RICHARDSON A, FEDOROFF S (1991) Macrophage-like cells originate from neuroepithelium in culture: characterization and properties of the macrophage-like cells. International Journal of Developmental Neuroscience 9, 1-14.
108. HARDESTY I (1904) On the development and nature of the neuroglia. American Journal of Anatomy 3: 229-268.
109. HARDY R, REYNOLDS R (1991) Proliferation and differentiation potential of rat forebrain oligodendroglial progenitors both in vitro and in vivo. Development 111, 1061-1080.
110. -oligodendroglial progenitors. Journal of Neuroscience Research 34, 589-600.
111. HART IK, RICHARDSON WD, HELDIN CH, WESTERMARK B, RAFF MC (1989) PDGF receptors on cells of the oligodendrocyte-type 2 astrocyte (O-2A) cell lineage. Development 105, 595-604.
112. HATTORI A, TANAKA E, MURASE K, ISHIDA N, CHATANI Y, TSUJIMOTO M et al. (1993) Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in nonneuronal cells. Journal of Biological Chemistry 268, 2577-2582.
113. HICKEY WF (1991) Migration of hematogenous cells through the blood brain barrier and the initiation of CNS inflammation. Brain Pathology 1, 97-105.
114. HIRSCHBERG DL, SCHWARTZ M (1995) Macrophage recruitment to acutely injured central nervous system is inhibited by a resident factor: a basis for an immune-brain barrier. Journal of Neuroimunology 61, 89-96.
115. HIRSCHBERG DL, YOLES E, BELKIN M, SCHWARTZ M (1994) Inflammation after axonal injury has conflicting consequences for recovery of function: rescue of spared axons is impaired but regeneration is supported. Journal of Neuroimmunology 50, 9-16.
116. HONMOU O, FELTS PA, WAXMAN SG, KOCSIS JD (1996) Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells. Journal of Neuroscience 16, 3199-3208
117. HOPKINS SJ, ROTHWELL NJ (1995) Cytokines and the nervous system. 1: expression and recognition. Trends in Neurosciences 18, 83-88.
118. HORTEGA P, DEL R (1921) Estudios sobre la neuroglia. La glia de escasas radiciones (oligodendroglia). Boletin de la Real Sociedad Espanola de la Historia Natural.
119. HORTEGA P, DEL R (1928) Tercera aportacia al conocimiento morfologico e interpretacion funcional de la oligodendroglia. Memoria de la Real Sociedad Espanola de la Historia Natural 14, 5-122.
120. HUGHES SM, LILLIEN LE, RAFF MC, ROHRER H, SENDTNER M (1988) Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture. Nature 335, 70-73.
121. HUNTER SF, BOTTENSTEIN JE (1989) Bipotential glial progenitors are targets of neuronal cell line-derived growth factors. Developmental Brain Research 49, 33-49.
122. HUNTER KE, SPORN MB, DAVIES AM (1993) Transforming growth factor-betas inhibit mitogen-stimulated proliferation of astrocytes. Glia 7, 203-211.
123. HUYNH HK, OGER J, DOROVINI-ZIS K (1995) Interferon-β down-regulates inter feron-γ induced class II molecule expression and morphological changes in primary cultures of human brain microvessel endothelial cells. Journal of Neuroimmunology 60, 63-73.
124. IMAMURA K, SUZUMURA A, SAWADA M, MABUCHI C, MARUNOUCHI T (1994) Induction of MHC class II antigen expression on murine microglia by interleukin-3. Journal of Neuroimmunology 55, 119-125.
125. ISACSON O, DEACON TW, PAKZABAN P, GALPERIN WR, DINSMORE J, BURNS KH (1995) Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres. Nature Medicine 11, 1189-1194.
126. JANZER RC, RAFF MC (1987) Astrocytes induce blood brain barrier properties in endothelial cells. Nature 325, 253-257.
127. JIANG H, MILO R, SWOVELAND P, JOHNSON KP, PANITCH H, DHIB-JALBUT S (1995) Interferon β1b reduces interferon γ-induced antigen-presenting capacity of human glial and B cells. Journal of Neuroimmunology 61, 17-25.
128. JUNG M, PESHEVA P, SCHACHNER M, TROTTER J (1993) Astrocytes and neurons regulate the expression of the neural recognition molecule janusin by cultured oligodendrocytes. Glia 9, 163-175.
129. KIERNAN BW, FFRENCH-CONSTANT C (1993) Oligodendrocyte precursor (O-2A progenitor cell) migration; a model system for the study of cell migration in the developing central nervous system. Development 119 (suppl) S219-S225.
130. KENNEDY PGE, FOK-SEANG J (1986) Studies on the development, antigenic phenotype, and function of human glial cells in tissue culture. Brain 109, 1261-1277.
131. KIM SU, MCMORRIS FA, SPRINKLE T (1984) Immunofluorescence demonstration of 2′: 3′ cyclic nucleotide phosphodiesterase in cultured oligodendrocytes of mouse, rat, calf and human. Brain Research 300, 195-199.
132. KITCHENS DL, SNYDER EY, GOTTLIEB DI (1994) FGF and EGF are mitogens for immortalized neural progenitors. Journal of N eurobiology 25, 797-807.
133. KLEITMAN N, WOOD PM, BUNGE RP (1991) Tissue culture methods for the study of myelination. In Culturing Nerve Cells (ed. Banker G, Goslin K), pp. 337-377. Cambridge, Massachusetts: MIT Press.
134. KNISS DA, BURRY RW (1988) Serum and fibroblast growth factor stimulate quiescent astrocytes to re-enter the cell cycle. Brain Research 439, 281-288.
135. KOMOLY S, HUDSON LD, DEF WEBSTER H, BONDY CA (1992) Insulin-like growth factor 1 gene expression is induced in astrocytcs during experimental demyelination. Proceedings of the National Academy of Sciences of the USA 89, 1894-1898.
136. KUNDU S, PLEATMAN M, REDWINE W, BOYD A, MARCUS D (1983) Binding of monoclonal antibody A2B5 to gangliosides. Biochemical and Biophysical Research Communications 116, 836-842.
137. LACY M, JONES J, WHITTEMORE SR, HAVILAND DL, WETSEL RA, BARNUM SR (1995) Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia. Journal of Neuroimmunology 61, 71-78.
138. LAENG P, DECIMO D, PETTMANN B, JANET T, LABOURDETTE G (1994) Retinoic acid regulates the development of oligodendrocyte precursor cells in vitro. Journal of Neuroscience Research 39, 613-633.
139. LARNER AJ, JOHNSON AR, KEYNES RJ (1995) Regeneration in the vertebrate central nervous system: phylogeny, ontogeny and mechanisms. Biological Reviews 70, 597-619.
140. LASSMANN H, ZIMPRICH F, VASS K, MICKEY WF (1991) Microglial cells are a component of the perivascular glia limitans. Journal of Neuroscience Research 28, 236-243.
141. LAYWELL ED, DORRIEN U, BARTSCH U, FAISSNER A, SCHACHNER M, STEINDLER DA (1992) Enhanced expression of the developmentally regulated extracellular matrix molecule tenascin following adult brain injury. Procedings of the National Academy of Sciences of the USA 89, 2634-2638.
142. LEE SC, LIU W, ROTH P, DICKSON DW, BERMAN JW, BROSNAN CF (1993a) Cytokine production by human fetal microglia and astrocytes. Journal of Immunology 150, 2659-2667.
143. LEE SC, LIU W, ROTH P, DICKSON DW, HERMAN JW, BROSNAN CF (1993b) Macrophage colony-stimulating factor in human fetal astrocytes and microglia: differential regulation by cytokines and lipopolysaccharide, and modulation of class II MHC on microglia Journal of Immunology 150, 594-604.
144. LEUTZ A, SCHACHNER M.(1981) Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures. Cell and Tissue Research 220, 393-404.
145. LEVINE JM (1989) Neuronal influences on glial progenitor cell development. Neuron 3, 103-113.
146. LEVINE JM, GOLDMAN JE (1988) Embryonic divergence of oligodendrocyte and astrocyte lineages in developing rat cerebrum. Journal of Neuroscience 8, 3992-4006.
147. LEVINE JM, STINCOME F, LEE Y-S (1993) Development and differentiation of glial precursor cells in the rat cerebellum. Glia 7, 307-321.
148. LEVISON SW, MCCARTHY KD (1990) Partial purification of a serum protein that induces the differentiation of type-2 astroglia. In Differentiation and Functions of Glial Cells: Procedings of a Satellite Meeting of the International Society for Neurochemisiry held in Rome, Italy, April 19-21, 1989 (ed. Levi G), pp. 103-105. New York: Alan R. Liss.
149. LEVISON SW, GOLDMAN JE (1993) Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron 10, 201-212.
150. LILLIEN LE, SENDTNER M, ROHRER H, HUGHES SM, RAFF MC (1988) Type-2 astrocyte development in rat brain cultures is initiated by a CNTF-like protein produced by type-1 astrocytes. Neuron 1, 485-494.
151. LILLIEN LE, SENDTNER M, RAFF MC (1990) Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development. Journal of Cell Biology 111, 635-644.
152. LINDHOLM D, HENGERER B, ZAFRA F, THOENEN H (1990) Transforming growth factor-beta 1 stimulates expression of nerve growth factor in the rat CNS. NeuroReport 1, 9-12.
153. LINDHOLM D, CASTREN E, KIEFER R, ZAFRA F, THOENEN H (1992) Transforming growth factor-B1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. Journal of Cell Biology 117, 395-400.
154. LININGTON C, WEBB M, WOODHAMS PL (1984) A novel myelim associated glycoprotein defined by a mouse monoclonal antibody. Journal of Neuroimmunology 6, 387-396.
155. LIUZZI FJ, LASEK RJ (1987) Astrocytes block axonal regeneration in mammals by activating the physiological stop pathway. Science 237, 642-645.
156. LOGAN A, FRAUTSCHY SA, GONZALEZ AM, SPORN MB, BAIRD A (1992) Enhanced expression of transforming growth factor beta 1 in the rat brain after a localised cerebral injury. Brain Research 587, 216-225.
157. LOGAN A, BERRY M, GONZALEZ AM, FRAUTSCHY SA, SPORN MB, BAIRD A (1994) Effects of transforming growth factor beta 1 on scar production in the injured central nervous system of the rat. European Journal of Neuroscience 6, 355-363.
158. LOIS C , ALVAREZ-BUYLLA A (1993) Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Procedings of the National Academy of Sciences of the USA 90, 2074-2077.
159. LOIS C, ALVAREZ-BUYLLA A (1994) Long distance neuronal migration in the adult mammalian, forebrain. Science 264,
160. LOUIS J-C, MAGAL E, TAKAYAMA S, VARON S (1993) CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death. Science 259, 689-692.
161. LUDWIN SK, SZUCHET S (1993) Myelination by mature ovine oligodendrocytes in vivo and in vitro: evidence that different steps in the myelination process are independently controlled. Glia 8, 219-231.
162. MCCARTHY KD, DE VELLIS J (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. Journal of Cell Biology 85, 890-902.
163. MCKEON RJ, SCHREIBER RC, RUDGE JS, SILVER J (1991) Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. Journal of Neuroscience 11, 3398-3411.
164. MCKERRACHER L, DAVID S, JACKSON DL, KOTTIS V, DUNN RJ, BRAUN PE (1994) Identification of myelin associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron 13, 805-811.
165. MCKINNON RD, DUBOIS-DALCQ M (1990) Fibroblast growth factor blocks myelin basic protein gene expression in differentiating O2A glial progenitor cells. Annals of the New York Academy of Sciences 605, 358-359.
166. MCKINNON RD, MATSUI T, DUBOIS-DALCQ M, AARONSON SA (1990) FGF modulates the PDGF-driven pathway of oligodendrocyte development. Neuron 5, 603-614.
167. MCKINNON RD, PIRAS G, IDA JA, DUBOIS-DALCQ M (1993) A role for TGF-beta in oligodendrocyte differentiation. Journal of Cell Biology 121, 1397-1407.
168. MCMILLIAN MK, THAI L, HONG J-S, O'CALLAGHAN JP, PENNY-PACKER KR (1994) Brain injury in a dish: a model for reactive gliosis. Trends in Neurosciences 17, 138-142.
169. MCMORRIS FA, DUBOIS-DALCQ ME (1988) Insulin-like growth factor 1 promotes cell proliferation and oligodendroglial commitment in rat progenitor cells developing in vitro. Journal of Neuroscience Research 21, 199-209.
170. MALE DK, PRYCE G, HUGHES CCW, LANTOS PL (1990) Lymphocyte migration into the brain modelled in vitro: control by lymphocyte activation, cytokines and antigen. Cellular Immunology 127, 1-11.
171. MALIPIERO UV, FREI K, FONTANA A (1990) Production of hemopoietic colony-stimulating factors by astrocytes. Journal of Immunology 144, 3816-3821.
172. MATHEWSON AJ, BERRY M (1985) Observations on the astrocyte response to a cerebral stab wound in adult rats. Brain Research 327, 61-69.
173. MAYER M, BOGLER O. NOBLE M (1993) The inhibition of oligodendrocytic differentiation of O-2A progenitors caused by basic fibroblast growth factor is overriden by astrocytes. Glia 8,
174. MEYER-FRANKE A, KAPLAN MR, PFEIGER FW, BARRES BA (1995) Characterisation of the signalling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 15, 805-819.
175. MILLER RH, FFRENCH-CONSTANT C, RAFF MC (1989 a) The macroglial cells of the rat optic nerve. Annual Reviews in the Neurosciences 12; 517-534.
176. MILLER RH, FULTON BP, RAFF MC (1989e) A novel type of glial cell associated with nodes of Ranvier in rat optic nerve. European Journal of Neuroscience 1, 172-180.
177. MOLLGARD K, SAUNDERS NR (1986) The development of the human blood brain and blood CSF barriers. Neuropathohgy and Applied Neurobioiogy 12, 337-358.
178. MORGAN TE, NICHOLS NR, PASINETTI GM, FINCH CE (1993) TGF-beta1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration. Experimental Neurology 120, 291-301.
179. MORI S, LEBLOND CP (1970) Electron microscope identification of three classes of oligodendrocyte and a preliminary study of their proliferative activity in the corpus callosum of young rats. Journal of Comparative Neurology 139, 1-30.
180. MORSHEAD CM, REYNOLDS BA, CRAIG CG, MCBURNEY MW, STAINES WA, MORASSUTTI D et al. (1994) Neural stem cells in the adult mammalian forebrain: a relatively quiescent sub-population of subependymal cells. Neuron 13, 1071-1082.
181. MUKHOPADHYAY G, DOHERTY P, WALSH FS, CROCKER PR, FILBIN MT (1994) A novel role for myelin associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13, 757-767.
182. MUIR D, COMPSTON DAS (1996) Growth factor stimulation triggers apoptotic cell death in mature rat oligodendrocytes. Journal of Neuroscience Research 44, 1-11.
183. NEWMAN EA (1986) High potassium conductance in astrocyte endfeet. Science 233, 453-454.
184. NISHIYAMA A, LIN XH, GIESE N, HELDIN CH, STALLCUP WB (1996) Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. Journal of Neuroscience Research 43, 299-314.
185. NOBLE M (1991) Points of controversy in the O-2A lineage: clocks and type 2 astrocytes. Glia 4, 157-164.
186. NOBLE M, MURRAY K, STROOBANT P, WATERFIELD MD, RIDDLE P (1988) Platelet derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type 2 astrocyte progenitor cell. Nature 333, 560-562.
187. NOJIRI H, STROUD M, HAKOMORI S-I (1991) A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity. Journal of Biological Chemistry 266, 4531-4537.
188. NONA SN, STAFFORD CA, DUNCAN A, CRONLY DILLON JR, SCHOLES J (1994) Myelin repair by Schwann cells in the regenerating goldfish visual pathway: regional patterns revealed by X-irradiation. Journal of Neurocytology 23, 400-409.
189. NORTON WT, CAMMER W (1984) Chemical pathology of diseases involving myelin. In Myelin (ed. Morrel P), pp. 369-404. New York: Plenum Press.
190. PATNO CL, BUNGE MB (1991) Induction of axon growth into Schwann cell implants grafted into lesioned adult rat spinal cord. Experimental Neurology 114, 254-257.
191. PENFIELD W (1924) Oligodendroglia and its relation to classical neuroglia. Brain 47, 430-452.
192. PENFIELD W (1932) Neuroglia, normal and pathological. In Cytology and Cellular Pathology of the Nervous System (ed. Penfield W), pp. 423-479. New York: Paul B. Hoeber.
193. PERRY VH, ANDERSSON PP, GORDON S (1991) Macrophages and inflammation in the central nervous system. Trends in Neurosciences 16, 268-273.
194. PETERS A (1964) Observations on the connexions between myelin sheaths and glial cells in the optic nerve of young rats. Journal of Anatomy 98, 125-34.
195. PETERS A, PALAY SL, WEBSTER HF (1976) The Fine Structure of the Nervous System: The Neurones and the Supporting Cells. Philadelphia: W, B. Saunders.
196. PETTMANN B, LABOURDETTE G, WEIBEL M, SENSENBRENNER M (1986) The brain fibroblast growth factor (FGF) is localised in neurons. Neuroscience Letters 68, 175-180.
197. PLEASURE SJ, LEE VMY (1993) A human cell line which displays characteristics expected of a human committed neuronal progenitor cell. Journal of Neuroscience Research 35, 585-602.
198. PINDZOLA RR, DOLLER C, SILVER J (1993) Putative inhibitory extracellular matrix molecules at the dorsal root entry zone of the spinal cord during development and after root and sciatic nerve lesions. Developmental Biology 156, 34-48.
199. POLTERAK M, SADOUL R, KEILHAUR G, LANDA C, FAHRIG T, SCHACHNER M (1987) Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neurone-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction. Journal of Cell Biology 105, 1893-1899.
200. PRINEAS JW, BARNARD RO, KWON EE, SHARER LR, CHO E-S (1993) Multiple sclerosis: remyelination of nascent lesions. Annals of Neurology 33, 137-151.
201. PRINGLE N, COLLARINI EJ, MOSLEY MJ, HELDIN C-H, WESTERMARK B, RICHARDSON WD (1989) PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial cells in the developing rat optic nerve. EMBO Journal 8, 1049-1056.
202. PRINGLE NP, MUDHAR HS, COLLARINI EJ, RICHARDSON WD (1992) PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development 115, 535-551.
203. PRIVAT A, LEBLOND CP (1972) The subependymal and neighbouring region in the brain of the young rat. Journal of Comparative Neurology 146, 277-301.
204. PRYCE G, MALE DK, SARKAR C (1991) Control of lymphocyte migration into brain: selective interactions of lymphocyte subpopulations with brain endothelium. Immunology 12, 393-396.
205. RAFF MC (1992) Social controls on cell survival and cell death. Nature 356, 397-400.
206. RAFF MC, FIELDS KL, HAKAMORI S-I, MIRSKY R, PRUSS RM, WINTER J (1979) Cell type specific markers for distinguishing and studying neurones and the major classes of glial cells in culture. Brain Research 174: 283-308.
207. RAFF MC, MILLER RH, NOBLE M (1983) A glial progenitor that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303, 390-396.
208. RAFF MC, WILLIAMS BP, MILLER RH (1984) The in vitro differentiation of a bipotential glial progenitor cell. EMBO Journal 3, 1857-1864.
209. RAFF MC, LILLIEN LE, RICHARDSON WD, BURNE JF, NOBLE MD (1988) Platelet derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333, 562-565.
210. RAINE CS (1984) The neuropathology of myelin diseases. In Myelin (ed. Morrell P), pp. 259-310. New York: Plenum Press.
211. RANSCHT B, CLAPSHAW PA, PRICE J, NOBLE M, SEIFERT W (1982) Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside. Proceedings of the National Academy of Sciences of the USA 79, 2709-2713.
212. RANSOM BR, BUTT AM, BLACK J (1991) Ultrastructural identification of HRP-injected oligodendrocytes in the intact rat optic nerve. Glia 4, 37-45.
213. RENDE M, MUIR D, RUOSLAHTI E, HAGG T, VARON S, MANTHORPE M (1992) Immunolocalisation of ciliary neurone-trophic factor in adult rat sciatic nerve. Glia 5, 25-32.
214. REVEL M, CHEBATH J, MANGELUS M, HARROCH S, MOVGLIA GA (1995) Antagonism of interferon beta and Interferon gamma: inhibition of signal transduction in vitro and reduction of serum J levels in multiple sclerosis patients. Multiple Sclerosis l, S5-S11.
215. REYNOLDS BA, WEISS S (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707-1710.
216. REYNOLDS BA, TETZLAFF W, WEISS S (1992) A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. Journal of Neuroscience 12, 4565-4574.
217. REYNOLDS, BA, WEISS, S (1996) Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Developmental Biology 175, 1-13.
218. REYNOLDS R, WILKIN GP (1988) Development of macroglial cells in rat cerebellum. II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cell. Development 102, 409-425.
219. REYNOLDS R, WILKIN GP (1991) Oligodendroglial progenitor cells but not oligodendroglia divide during normal development of the rat cerebellum. Journal of Neurocytology 20, 216-224.
220. RICHARDSON PM, MCGUINNESS U, AGUAYO AJ (1980) Axons from CNS neurons regenerate into PNS grafts. Nature 284, 264-265.
221. RICHARDSON PM, LU X (1994) Inflammation and axonal regeneration. Journal of Neurology 242 (suppl): S57-S60.
222. RICHARDSON WD, PRINGLE N, MOSLEY MJ, WESTERMARK B, DUBOIS-DALCQ M (1988) A role for platelet-derived growth factor in normal gliogenesis in the central nervous system. Cell 53, 309-319.
223. RIECKMANN P, MICHEL U, ALBRECHT M, BRUCK W, WOCKEL L, FELGENHAUER K (1995) Soluble forms of intercellular adhesion molecule-1 (ICAM-1) block lymphocyte attachment to cerebral endothelial cells. Journal of Neuroimmunology 60, 9-15.
224. RISAU W (1991) Induction of blood-brain barrier endothelial cell differentiation. Annals of the New York Academy of Sciences 633, 405-419.
225. RIVKIN MJ, FLAX J, MOZELL R, OSATHANONDH R, VOLPE JJ, VILLA-KOMAROFF L (1995) Oligodendroglial development in human fetal cerebrum. Annals of Neurology 38, 92-101.
226. ROBERTSON WF (1899) On a new method of obtaining a black reaction in certain tissue elements of the central nervous system (platinum method). Scottish Medical and Surgical Journal 4, 23-30.
227. ROGISTER B, LEPRINCE P, DELREE P, VAN-DAMME J, BILLIAU A, MOONEN G (1990) Enhanced release of plasminogen activator inhibitors but not of plasminogen activators by cultured rat glial cells treated with interleukin-1. Glia 3, 252-257.
228. ROGISTER B, DEIREE P, LEPRINCE P, MARTIN D, SADZOT C, MALGRANGE B et al. (1993) Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury. Journal of Neuroscience Research 34, 32-43.
229. ROSEN CL, BUNGE RP, ARD MD, WOOD PM (1989) Type 1 astrocytes inhibit myelination by adult rat oligodendrocytes in vitro. Journal of Neuroscience 9, 3371-3379.
230. ROTHWELL NJ, HOPKINS SJ (1995) Cytokines and the nervous system. II: Actions and mechanisms of action. Trends in Neurosciences 18, 130-136.
231. RUDGE JS, SILVER J (1990) Inhibition of neurite outgrowth on astroglial scars in vitro. Journal of Neuroscience 10, 3594-3603.
232. SALLES FJ, SCHECHTER N, STRICKLAND SA (1990) Plasminogen activator is induced during goldfish optic nerve regeneration. EMBO Journal 9, 2471-2477.
233. SARLIEVE LL, DELAUNDY JP, DIERICH A, EBEL A, FABRE M, MAXDEL P et al. (1981) Investigations on myelination in vitro III. Ultrastructural: Brain cells from embryonic mice. Journal of Neuroscience Research 6, 659-683.
234. SASAHARA M, FRIES JWU, RAINES EW, GOWN AM, WESTRUM LE, FROSCH MP et al. (1991) PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model. Cell 64, 217-227.
235. SATOH J, KIM SU (1994) Proliferation and differentiation of fetal human oligodendrocytes in vitro. Journal of Neuroscience Research 39, 260-272.
236. SAWADA M, KONDO N, SUZUMURA A, MARUNOUCHI T (1989) Production of tumor necrosis factor-alpha by microglia and astrocytes in culture. Brain Research 491, 394-397.
237. SAWADA M. SUZUMURA A, MARUNOUCHI T (1992) TNF alpha induces IL-6 production by astrocytes but not microglia. Brain Research 538, 296-299.
238. SAWADA M, SUZUMURA A, ITOH Y, MARUNOUCHI T (1993) Production of interleukin-5 by mouse astrocytes and microglia in culture. Neuroscience Letters 155, 175-178.
239. SCRAPER A (1897) Die fruhesten Differenzierungsvorgange in Zentralnervensystem. Rouxs Archiv für Entwicklungsmechanik der Organismen 5, 8-132.
240. SCHNELL L, SCHWAB ME (1990) Axonal regeneration in the rat spinal cord produced by an antibody against myelin associated neurite growth inhibitors. Nature 343, 269-272.
241. SCHWAB ME (1990) Myelin-associated inhibitors of neurite growth and regeneration in the CNS. Trends in Neurosciences 13, 452-456.
242. SCHWAB ME, KAPFHAMMER JP, BANDTLOW CE (1993) Inhibitors of neurite growth. Annual Reviews in the Neurosciences 16, 565-595.
243. SCOLDING NJ, HOUSTON WAJ, LININGTON C, MORGAN BP, CAMPBELL AK, COMPSTON DAS (1989 a) Oligodendrocytes activate complement but recover by vesicular removal of membrane attack complexes. Nature 338; 620-622.
244. SCOLDING NJ, FRITH S, LININGTON C, MORGAN BP, CAMPBELL AK, COMPSTON DAS (1989b) The myelin-oligodendrocyte glycoprotein (MOG) antigen is a surface marker of oligodendrocyte maturation. Journal of Neuroimmunology 22, 169-176.
245. SCOLDING NJ, MORGAN BP, CAMPBELL AK, COMPSTON DAS (1992) The role of calcium in rat oligodendrocyte injury and repair. Neuroscience Letters 135, 95-97.
246. SCOLDING NJ, COMPSTON DAS (1995) Growth factors fail to protect Oligodendrocytes against humoral injury in vitro. Neuroscience Letters 183, 75-78.
247. SCOLDING NJ, RAYNER PJ, SUSSMAN J, SHAW C, COMPSTON DAS (1995) A proliferative adult human oligodendrocyte progenitor. NeuroRepon 6, 441-445.
248. SEILHEAN D, GANSMULLER, A BARON-VAN EVERCOOREN, GUMPEL M, LACHAPELLE F (1996) Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation. Acta Neuropathologica 91, 82-88.
249. SHAH NM, MARCHIONNI MA, ISAACS I, STROOBANT P, ANDERSON DJ (1994) Glial growth factor restricts mammalian neural crest stem cells to a glial fate. Cell 77, 349-360.
250. SHAW CE, MILNER RM, COMPSTON DAS, FFRENCH-CONSTANT C (1996) Integrin expression during axo-glial interactions : a developmental comparison of Oligodendrocytes and Schwann cells. Journal of Neuroscience 16, 1163-1172.
251. SHIMOJO M, NAKAJIMA K, TAKEI N, HAMANOUE M, KOHSAKA S (1991) Production of basic fibroblast factor in cultured rat brain microglia. Neuroscience Letters 123, 229-231.
252. SIVRON T, SCHWARTZ M (1994) The enigma of myelin-associated growth inhibitors in spontaneously regenerating nervous systems. Trends in Neurosciences 17, 277-281.
253. SKOFF RP (1990) Gliogenesis in rat optic nerve: astrocytes are generated in a single wave before Oligodendrocytes. Developmental Biology 139, 149-168.
254. SKOFF R, PRICE D, STOCKS A (1976) Electron microscope autoradiographic studies of gliogenesis in rat optic nerve. I. Cell proliferation. Journal of Comparative Neurology 169, 291-312.
255. SKOFF RP, KNAPP PE (1991) Division of astroblasts and oligodendroblasts in postnatal rodent brain: evidence for separate astrocyte and oligodendrocyte lineages. Glia 4, 165-174.
256. SMALL RK, RIDDLE P, NOBLE M (1987) Evidence for migration of oligodendrocyte-type 2 astrocyte progenitor cells into the developing rat optic nerve. Nature 328, 155-157.
257. SMITH GM, RUTISHAUSER U, SILVER J, MILLER RH (1990) Maturation of astrocytes in vitro alters the extent and molecular basis of neurite outgrowth. Developmental Biology 138, 377-390.
258. SMITH KJ, BLAKEMORE WF, MCDONALD WI (1979) Central remyelination restores secure conduction. Nature 280, 395-396.
259. SMITH KJ, BLAKEMORE WF, MCDONALD WI (1981) The restoration of conduction by central remyelination. Brain 104, 383-404.
260. SMITS A, KATO M, WESTERMARK B, NISTER M, HELDIN C-H, FUNA K (1991) Neurotrophic activity of platelet-derived growth factor (PDGF): rat neuronal cells possess functional PDGF β-type receptors and respond to PDGF. Procedings of the National Academy of Sciences of the USA 88, 8159-8163.
261. SPRANGER M, LlNDHOLM D, BANDTLOW C, HEUMAN R, GNAHN H, NAHER NOE M et al. (1990) Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system : comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo. European Journal of Neuroscience 2, 69-76.
262. SPRINKLE T, WELLS M, CARVER F, SMITH D (1980) Studies on Wolfgram high molecular weight CNS proteins : relationship to 2′-3′-cyclic nucleotide 3′-phosphohydrolase. Journal of Neurochemistry 35, 1200-1208.
263. STEMPLE DL, ANDERSON DJ (1992) Isolation of a stem cell for neurons and glia from the mammalian neural crest. Cell 71, 973-985.
264. SUZUMURA A, SAWADA M, YAMAMOTO H, MARUNOUCHI T (1993) Transforming growth factor beta suppresses activation and proliferation of microglia in vitro. Journal of Immunology 151, 2150-2158.
265. SUZUMURA A, SAWADA M, ITOH Y, MARUNOUCHI T (1994) Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression. Journal of Neuroimmunology 53, 209-218.
266. TAO-CHENG JH, BRIGHTMAN MW (1988) Development of membrane interactions between brain endothelial cells and astrocytes in vitro. International Journal of Developmental Neuroscience 6, 5-37.
267. TARGETT MP, SUSSMAN J, SCOLDING NJ, O'LEARY MT, COMPSTON DAS, BLAKEMORE WF (1996) Failure to remyelinate rat axons following transplantation of glial cells obtained from the adult human brain. Neuropathology and Applied Neurobiology 22, 199-206.
268. TEMPLE S (1989) Division and differentiation of isolated CNS blast cells in microcultures. Nature 340, 471-473.
269. TROTTER J, SCHACHNER M (1989) Cells positive for the 04 surface antigen isolated by cell sorting are able to differentiate into astrocytes or oligodendrocytes. Developmental Brain Research 46, 115-122.
270. TROTTER J, CRANG AJ, SCHACHNER M, BLAKEMORE WF (1993) Lines of glial precursor cells immortalised with a temperature-sensitive oncogene give rise to astrocytes and oligodendrocytes following transplantation into demyelinated lesions in the central nervous system. Glia 9, 25-40.
271. TURNER DL, CEPKO C (1988) A common progenitor cell for neurones and glia precursor cells persists in rat retina late in development. Nature 328, 131-136.
272. UTZSCHNEIDER D, BLACK JA, KPCSOS JD (1992) Conduction properties of spinal cord axons in the myelin deficient rat mutant. Neuroscience 49, 221-228.
273. UTZSCHNEIDER D, ARCHER DR, KOCSIS JD, WAXMAN SG, DUNCAN ID (1994) Transplantation of glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin deficient rat. Proceedings of the National Academy of Sciences of the USA 91, 53-57.
274. +, flat astrocyte in rat CNS cultures. Journal of Neuroscience 12, 330-337.
275. VEDELER C, ULVESTAD E, GRUNDT I, CONTI G, NYLAND H, MATRE R et al. (1994) Fc receptor for IgG (FcR) on rat microglia. Journal of Neuroimmunology 49, 19-24.
276. VESCOVI AL, REYNOLDS BA, FRASER DD, WEISS S (1993) bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) ;EGF-generated CNS progenitor cells. Neuron 11, 951-966.
277. VIGE X, TANG B, WISE BC (1992) Cortical neurons inhibit basal and interleukin-1 -stimulated astroglial cell secretion of nerve growth factor. Brain Research 591, 345-350.
278. VIGNAIS L, OUMESMAR BN, BARON VAN EVERCOOREN A (1995) PDGF-alpha receptor is expressed by mature neurones of the central nervous system. NeuroReport 6, 1993-1996.
279. VIRCHOW R (1858) Cellularpathologie in ihre Begrundung auf physiologische und pathologische Gewebelehre. Berlin: A. Hirschwald, Berlin.
280. + oligodendrocytes in postnatal cerebellum: analysis in unfixed tissue slices using anti-glycolipid antibodies. Journal of Neuroscience Research 33, 338-353.
281. WARRINGTON AE, BARBARESE E, PFEIFFER SE (1993) Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypo-myelinating hosts. Journal of Neuroscience Research 34, 1-13.
282. WEBB A, CLARK P, SKEPPER J, COMPSTON DAS, WOOD AT (1995) Guidance of oligodendrocytes and their progenitors by substratum topography. Journal of Cell Science 108, 2747-2760.
283. WEIDENHEIM KM, EPSHTEYN I, RASHBAUM WK, LYMAN WD (1994) Patterns of glial development in the human foetal spinal cord during the late first and second trimester. Journal of Neurocytology 23, 343-353.
284. WEISS S, REYNOLDS BA, VESCOVI AL, MORSHEAD C, CRAIG C, VAN DER KOOY D (1996) Is there a neural stem cell in the mammalian forebrain? Trends in Neuroscience 19, 387-393.
285. WEKERLE H, LININGTON C, LASSMANN H, MEYERMAN R (1986) Cellular immune reactivity within the CNS. Trends in Neurosciences 9, 271-277.
286. WHITTEMORE SR, SANON HR, WOOD PM (1993) Concurrent isolation and characterisation of oligodendrocytes, microglia and astrocytes from adult human spinal cord. International Journal of Developmental Neuroscience 11, 755-764.
287. WILLIAMS BP, READ J, PRICE J (1991) The generation of neurons and oligodendrocytes from a common precursor cell. Neuron 7, 685-693.
288. WILLIAMS BP, PRICE J (1995) Evidence for multiple precursor cell types in the embryonic rat cerebral cortex. Neuron 8, 1181-1188.
289. WILLIAMS K, BAR-OR A, ULVESTAD E, OLIVER A, ANTEL J, YONG VW (1992) Biology of adult human microglia in culture: comparison with peripheral blood monocytes and astrocytes. Journal of Neuropathology and Experimental Neurology 51, 538-549.
290. WILLIAMS K, ULVESTAD E, BLOIN M, ANTEL JP (1993) Induction of primary T cell responses by human glial cells. Journal of Neuroscience 36, 382-390.
291. WILLIAMS KE, ULVESTAD E, ANTEL JP (1994) B7/BB-1 antigen expression on adult human microglia studied in vitro and in situ. European Journal of Immunology 24, 3031-3037.
292. WING MG, SEILLY DJ, RAHMAN S, ZAJICEK JP, LACHMANN PJ, COMPSTON DAS (1996) Comparison of the regulation and specificity of the rat C1q-receptors on peritoneal macrophages and brain microglia. Immunology, in press.
293. WOOD PM, WILLIAMS AK (1984) Oligodendrocyte proliferation and CNS myelination in cultures containing dissociated embryonic neuroglia and dorsal root ganglion neurons. Development and Brain Research 12, 225-241.
294. WOOD PM, BUNGE RP (1986) Myelination of cultured dorsal root ganglion neurons by oligodendrocytes obtained from adult rats. Journal of the Neurological Sciences 74, 153-169.
295. WOOD PM, BUNGE RP (1991) The origin of remyelinating cells in the adult central nervous system: the role of the mature oligodendrocyte. Glia 4, 225-232.
296. WOODROOFE MN, HAYES GM, CUZNER ML (1989) Fc receptor density, MHC antigen expression and Superoxide production are increased in interferon-γ-treated microglia isolated from adult rat brain. Immunology 68, 421-426.
297. WOLSWIJK G (1995) Strongly GD3 + ye cells in the developing and adult-rat cerebellum belong to the microglial lineage rather than V to the oligodendrocyte lineage. Glia 13, 13-26.
298. WOLSWIJK G, NOBLE M (1989) Identification of an adult specific glial progenitor cell. Development 105, 387-400.
299. WOLSWIJK G, NOBLE M (1992) Co-operation between PDGF and FGF converts slowly dividing 0-2A (adult) progenitor cells to rapidly dividing cells with characteristics of O-2A (perinatal) progenitor cells. Journal of Cell Biology 118, 889-900.
300. adult progenitor cells. Journal of Cell Biology 116, 176-176.
301. WUCHERPFENNIG KW, WEINER HL, HAFLER DA (1991) T-cell recognition of myelin basic protein. Immunology Today 12, 277-282.
302. YAO D-L, LIU X, HUDSON LD, WEBSTER HDEF (1995) Insulin-like growth factor 1 treatment reduces demyelination and upregulates gene expression of myelin related proteins in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the USA 92, 6190-6194.
303. YASUDA T, GRINSPAN J, STERN J, FRANCESCHINI B, BANNERMAN P, PLEASURE D (1995) Apoptosis occurs in the oligodendroglial lineage, and is prevented by basic fibroblast growth factor. Journal of Neuroscience Research 40, 306-317.
304. YEH HJ, RUIT KG, WANG YX, PARKS WC, SNIDER WD, DEUEL TF (1991) PDGF A-chain is expressed in mammalian neurons during development and in maturity. Cell 64, 209-216.
305. YIM SH, SZUCHET S, POLAK PE (1986) Cultured oligodendrocytes; a role for cell-substratum interaction in phenotypic expression. Journal of Biological Chemistry 261, 11808-11815.
306. YONG VW, MOUMDJIAN R, YONG FP, RUIJS TCG, FREEDMAN MS, CASHMAN N et al. (1991) Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo. Proceedings of the National Academy of Sciences of the USA 88, 7016-7020.
307. YOSHIDA K, GAGE FH (1992) Cooperative regulation of nervegrowth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines. Brain Research 569, 14-25.
308. YU WP, COLLARTNl EJ, PRINGLE NP, RICHARDSON WD (1994) Embryonic expression of myelin genes: evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube. Neuron 12, 1353-1362.
309. ZAJICEK JP, COMPSTON DAS (1994) Myelination in vitro of dorsal root ganglia by glial progenitor cells. Brain 117, 1333-1350.
310. ZALC B, MONGE M, DUPOUEY P, HAWW JJ, BARMAN NA (1981) The localisation of galactosyl and sulfogalactosyl ceramide in the brain of the 30 day old mouse. Brain. Research 211, 341-54.