Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma

Cancer Research

Volumn 57, Issue 1, 1997, Pages 28-31

  Tanaka, Shinji ^a   Mori, Masaki ^a   Akiyoshi, Tsuyoshi ^a   Tanaka, Youichi ^c   Mafune, Ken Ichi ^c   Wands, Jack R ^d   Sugimachi, Keizo ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c SAITAMA CANCER CENTER   (Japan)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE;

ADVANCED CANCER; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER INVASION; CARCINOGENESIS; DISEASE ASSOCIATION; ENZYME ACTIVITY; ESOPHAGUS CARCINOMA; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; ESOPHAGEAL NEOPLASMS; GRB7 ADAPTOR PROTEIN; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RNA, MESSENGER;

EID: 0031034760     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Ullrich, A., and Schlessinger, J. Signal transduction by receptors with tyrosine kinase activity. Cell, 61: 203-211, 1990.
2. Pawson, T. Protein modules and signaling networks. Nature (Lond.), 373: 573-580, 1995.
3. Skolnik, E. Y., Margolis, B., Mohammadi, M., Lowenstein, E., Fischer, R., Drepps, A., Ullrich, A., and Schlessinger, J. Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell, 65: 83-90, 1991.
4. Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., and Schlessinger, J. The SH2 and SH3 domain- containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell, 70: 431-442, 1992.
5. Margolis, B., Silvennoinen, O., Comoglio, F., Roonprapunt, C., Skolnik, E. Y., Ullrich, A., and Schlessinger, J. High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. Proc. Natl. Acad. Sci. USA, 89: 8894-8898, 1992.
6. Ooi, J., Yajnik, V., Immanuel, D., Gordon, M., Moskow, J. J., Buchberg, A. M., and Margolis, B. The cloning of Grb10 reveals a new family of SH2 domain proteins. Oncogene, 10: 1621-1630, 1995.
7. Tanaka, S., Ito, T., and Wands, J. R. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules. J. Biol. Chem., 271: 14610-14616, 1996.
8. Stein, D., Wu, J., Fuqua, S. A. W., Roonprapunt, C., Yajnik, V., Moskow, J. J., Buchberg, A. M., Osborne, C. K., and Margolis, B. The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer. EMBO J., 13: 1331-1340, 1994.
9. Sugimachi, K., Watanabe, M., Sadanaga, N., Ikebe, M., Kitamura, K., Mori, M., and Kuwano, H. Recent advances in the diagnosis and surgical treatment of patients with carcinoma of the esophagus. J. Am. Coll. Surg., 178: 363-368, 1994.
10. Yoshida, K., Kuniyasu, H., Yasui, W., Kitadai, Y., Toge, T., and Tahara, E. Expression of growth factors and their receptors in human esophageal carcinomas: regulation of expression by epidermal growth factor and transforming growth factor a. J. Cancer Res. Clin. Oncol., 119: 401-407, 1993.
11. Ozawa, S., Yeda, M., Ando, N., Shimizu, N., and Abe, O. Prognostic significance of epidermal growth factor receptor in esophageal squamous cell carcinoma. Cancer (Phila.), 63: 2169-2173, 1989.
12. Shiga, K., Shiga, C., Sasano, H., Miyazaki, S., Yamamoto, T., Yamamoto, M., Hayashi, N., Nishihira, T., and Mori, S. Expression of c-erbB-2 in human esophageal carcinoma cells: overexpression correlated with gene amplification or with GATA-3 transcription factor expression. Anticancer Res., 13: 1293-1302, 1993.
13. Hollstein, M. C., Smits, A. M., Galiana, C., Yamasaki, H., Bos, J. L., Mandard, A., Partensky, C., and Montesano, R. Amplification of epidermal growth factor receptor gene but no evidence of ras mutations in primary human esophageal cancers. Cancer Res., 48: 5119-5123, 1988.
14. Mori, M., Mimori, K., Inoue, H., Barnard, G. F., Tsuji, K., Nanbara, S., Ueo, H., and Akiyoshi, T. Detection of cancer micrometastasese in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res., 55: 3417-3420, 1995.
15. Ji, H., Zhang, Q., and Leung, B. S. Survey of oncogene and growth factor/receptor gene expression in cancer cells by intron-differential RNA/PCR. Biochem. Biophys. Res. Commun., 170: 569-675, 1990.
16. Sarker, F. H., Visscher, D. W., and Crissman, J. D. Quantitative analysis of Her-2/neu (ERBB2) gene expression using reverse transcriptase polymerase chain reaction. Diagn. Mol. Pathol., 2: 210-218, 1993.
17. Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. The PH domain, a common piece in the structural patchwork of signalling proteins. Trends Biol. Sci., 18: 343-348, 1993.
18. Touhara, K., Inglese, J., Pitcher, J. A., Show, G., and Lefkowitz, R. J. Binding of G protein beta gamma-subunits to pleckstin homology domains. J. Biol. Chem., 269: 10217-10220, 1994.
19. Harlen, J. E., Hajduk, P. J., Yoon, H. S., and Feski, S. W. Pleckstin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature (Lond.), 371: 168-170, 1994.
20. Tanaka S., and Wands, J. R. A carboxy-terminal truncated IRS-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype. J. Clin. Invest., 98: 2100-2108, 1996.