Peroxisome biogenesis

BioEssays

Volumn 19, Issue 1, 1997, Pages 57-66

  Waterham, Hans R ^a   Cregg, James M ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA;

EID: 0031032677     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.950190110     Document Type: Review

References (74)

1. Masters, C. and Crane, D. (1995). The Peroxisome: A Vital Organelle. Cambridge University Press, Cambridge.
2. Olsen, L. J. and Harada, J. J. (1995). Peroxisomes and their assembly in higher plants. Annu. Rev. Plant Physiol. 46, 123-146.
3. Clayton, C., Häusler, T. and Blattner, J. (1995). Protein trafficking in kinetoplastid protozoa. Microbiol. Rev. 59, 325-344.
4. van den Bosch, H., Schutgens, R. B. H., Wanders, R. J. A. and Tager, J. M. (1992). Biochemistry of peroxisomes. Annu. Rev. Biochem. 61, 157-197.
5. Lazarow, P. B. and Moser, H. W. (1994). Disorders in peroxisome biogenesis. In The Metabolic Basis of Inherited Disease, 7th edn (ed. C. R. Scriver, A. L. Beaudet, W. S. Sly and D. Valle), pp. 2287-2324. McGraw Hill, New York.
6. Slawecki, M. L., Dodt, G., Steinberg, S., Moser, A. B., Moser, H. W. and Gould, S. J. (1995). Identification of three distinct peroxisomal protein import defects in patients with peroxisome biogenesis disorders. J. Cell Sci. 108, 1817-1829.
7. Veenhuis, M. and Harder, W. (1991). Microbodies. In The Yeasts, Vol. 4, 2nd edn (ed. A. H. Rose and J. S. Harrison), pp. 601-653. Academic Press, London.
8. Erdmann, R., Veenhuis, M., Mertens, D. and Kunau, W.-H. (1989). Isolation of peroxisome-deficient mutants of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 86, 5419-5423.
9. Cregg, J. M., van der Klei, I. J., Sulter, G. J., Veenhuis, M. and Harder, W. (1990). Peroxisome-deficient mutants of Hansenula polymorpha. Yeast 6, 87-97.
10. Liu, H., Tan, X., Veenhuis, M., McCollum, D. and Cregg, J. M. (1992). An efficient screen for peroxisome-deficient mutants of Pichia pastoris. J. Bacteriol. 174, 4943-4951.
11. Gould, S. J., McCollum, D., Spong, A. P., Heyman, J. A. and Subramani, S. (1992). Development of the yeast Pichia pastoris as a model organism for a genetic and molecular analysis of peroxisome assembly. Yeast 8, 613-628.
12. Nuttley, W. M. et al. (1993). Rapid identification and characterization of peroxisomal assembly mutants in Yarrowia lipolytica. Yeast 9, 507-517.
13. Distel, B. et al. (1996). A unified nomenclature for peroxisome biogenesis. J. Cell Biol. 135, 1-3.
14. Subramani, S. (1993). Protein import into peroxisomes and biogenesis of the organelle. Annu. Rev. Cell Biol. 9, 445-478.
15. Santos, M. J., Imanaka, T., Shio, H., Small, G. M. and Lazarow, P. B. (1988). Peroxisomal membrane ghosts in Zellweger syndrome - aberrant organelle assembly. Science 239, 1536-1538.
16. Sulter, G. J., Vrieling, E. G., Harder, W. and Veenhuis, M. (1993). Synthesis and subcellular location of peroxisomal membrane proteins in a peroxisome-deficient mutant of the yeast Hansenula polymorpha. EMBO J. 12, 2205-2210.
17. Purdue, P. E. and Lazarow, P. B. (1995). Identification of peroxisomal membrane ghosts with an epitope-tagged integral membrane protein in yeast mutants lacking peroxisomes. Yeast 11, 1045-1060.
18. Waterham, H. R., Titorenko, V. I., Swaving, G. J., Harder, W. and Veenhuis, M. (1993). Peroxisomes in the methylotrophic yeast Hansenula polymorpha do not necessarily derive from pre-existing organelles. EMBO J. 12, 4785-4794.
19. Tan, X., Waterham, H. R., Veenhuis, M. and Cregg, J. M. (1995). The Hansenula polymorpha PER8 gene encodes a novel peroxisomal integral membrane protein involved in proliferation. J. Cell Biol. 128, 307-319.
20. Erdmann, R. and Blobel, G. (1995). Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p. J. Cell Biol. 128, 509-523.
21. Marshall, P. A. et al. (1995). Pmp27 promotes peroxisomal proliferation. J. Cell Biol. 129, 345-355.
22. Rapp, S. et al. (1996). Microtubule-based peroxisome movement. J. Cell Science 109, 837-849.
23. Walton, P. A., Wendland, M., Subramani, S., Rachubinski, R. A. and Welch, W. J. (1994). Involvement of 70-kD heat-shock proteins in peroxisomal import. J. Cell Biol. 125, 1037-1046.
24. de Hoop, M. J. and AB, G. (1992). Import of proteins into peroxisomes and other microbodies. Biochem. J. 286, 657-669.
25. Gould, S. J., Keller, G.-A. and Subramani, S. (1987). Identification of a peroxisomal targeting signal at the carboxy terminus of firefly luciferase. J. Cell Biol. 105, 2923-2931.
26. Swinkels, B. W., Gould, S. J., Bodnar, A. G., Rachubinski, R. A. and Subramani, S. (1991). A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase. EMBO J. 10, 3255-3262.
27. Glover, J. R., Andrews, D. W., Subramani, S. and Rachubinski, R. A. (1994). Mutagenesis of the amino targeting signal of the Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for the import into peroxisomes in vivo. J. Biol. Chem. 269, 7558-7563.
28. Gietl, C., Faber, K. N., van der Klei, I. J. and Veenhuis, M. (1994). Mutational analysis of the N-terminal topogenic signal of watermelon glyoxysomal malate dehydrogenase using the heterologous host Hansenula polymorpha. Proc. Natl Acad. Sci. USA 91, 3151-3155.
29. Blattner, J., Swinkels, B., Dorsam, H., Prospero, T., Subramani, S. and Clayton, C. (1992). Glycosome assembly in trypanosomes: variations in the acceptable degeneracy of a COOH-terminal microbody targeting signal. J. Cell Biol. 119, 1129-1136.
30. Kragler, F., Langeder, A., Raupachova, J., Binder, M. and Hartig, A. (1993). Two independent peroxisomal targeting signals in catalase A of Saccharomyces cerevisiae. J. Cell Biol. 120, 665-673.
31. Small, G. M., Szabo, L. J. and Lazarow, P. B. (1988). Acyl-CoA oxidase contains two targeting sequences each of which mediate protein import into peroxisomes. EMBO J. 7, 1167-1173.
32. McCammon, M. T., McNew, J. A., Willy, P. J. and Goodman, J. M. (1994). An internal region of the peroxisomal membrane protein PMP47 is essential for sorting to peroxisomes. J. Cell Biol. 124, 915-925.
33. Dyer, J. M., McNew, J. A. and Goodman, J. M. (1996). The sorting sequence of the peroxisomal integral membrane protein PMP47 is contained within a short hydrophilic loop. J. Cell Biol. 133, 269-280.
34. Rachubinski, R. A. and Subramani, S. (1995). How proteins penetrate peroxisomes. Cell 83, 525-528.
35. McCollum, D., Monosov, E. and Subramani, S. (1993). The pas8 mutant of Pichia pastoris exhibits the peroxisomal import deficiencies of Zellweger syndrome cells - the PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family. J. Cell Biol. 121, 761-774.
36. Terlecky, S. R., Nuttley, W. M., McCollum, D., Sock, E. and Subramani, S. (1995). The Pichia pastoris peroxisomal protein PAS8p is the receptor for the C-terminal tripeptide peroxisomal targeting signal. EMBO J. 14, 3627-3634.
37. Dodt, G. et al. (1995). Mutations of the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders. Nat. Genet. 9, 115-125.
38. Wiemer, E. A. C. et al. (1995). Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders. J. Cell Biol. 130, 51-65.
39. Fransen, M. et al. (1995). Identification and characterization of the putative human peroxisomal C-terminal targeting signal import receptor. J. Biol. Chem. 270, 7731-7736.
40. van der Klei, I. J. et al. (1995). The Hansenula polymorpha PER3 gene is essential for the import of PTS1 proteins into the peroxisomal matrix. J. Biol. Chem. 270, 17229-17236.
41. Nuttley, W. M., Szilard, R. K., Smith, J. J., Veenhuis, M. and Rachubinski, R. A. (1995). The PAH2 gene is required for peroxisome assembly in the methylotrophic yeast Hansenula polymorpha and encodes a member of the tetratricopeptide repeat family of proteins. Gene 160, 33-39.
42. Szilard, R. K., Titorenko, V. I., Veenhuis, M. and Rachubinski, R. A. (1995). Pay32p of the yeast Yarrowia lipolytica is an intraperoxisomal component of the matrix protein translocation machinery. J. Cell Biol. 131, 1453-1469.
43. Marzioch, M., Erdmann, R., Veenhuis, M. and Kunau, W.-H. (1994). PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes. EMBO J. 13, 4908-4918.
44. Zhang, J. W. and Lazarow, P. B. (1995). PEB1 (PAS7) in Saccharomyces cerevisiae encodes a hydrophilic, intra-peroxisomal protein that is a member of the WD repeat family and is essential for the import of thiolase into peroxisomes. J. Cell Biol. 129, 65-80.
45. Rehling, P., Marzioch, M., Niesen, F., Wittke, E., Veenhuis, M. and Kunau, W.-H. (1996). The import receptor for the peroxisomal targeting signal 2 (PTS2) in Saccharomyces cerevisiae is encoded by the PAS7 gene. EMBO J. 15, 2901-2913.
46. 2-terminal peptide. J. Cell Biol. 132, 325-334.
47. Erdmann, R. and Blobel, G. (1996). Identification of Pex13p, a peroxisomal membrane receptor for the PTS1 recognition factor. J. Cell Biol. 135, 111-121.
48. Erdmann, R. et al. (1991). PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases. Cell 64, 499-510.
49. Spong, A. P. and Subramani, S. (1993). Cloning and characterization of PAS5: a gene required for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris. J. Cell Biol. 123, 535-548.
50. Nuttley, W. M. et al. (1994). PAY4, a gene required for peroxisome assembly in the yeast Yarrowia lipolytica, encodes a novel member of a family of putative ATPases. J. Biol. Chem. 269, 556-566.
51. Tsukamoto, T. et al. (1995). Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation of a peroxisome-deficient mammalian cell mutant. Nat. Genet. 11, 395-401.
52. Yahraus, T. et al. (1996). The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor. EMBO J. 15, 2914-2923.
53. Wiebel, F. F. and Kunau, W.-H. (1992). The Pas2 protein essential for peroxisome biogenesis is related to ubiquitin-conjugating enzymes. Nature 359, 73-76.
54. Crane, D. I., Kalisch, J. E. and Gould, S. J. (1994). The Pichia pastoris PAS4 gene encodes a ubiquitin-conjugating enzyme required for peroxisome assembly. J. Biol. Chem. 269, 21835-21844.
55. Tsukamoto, T., Miura, S. and Fujiki, Y. (1991). Restoration by a 35K membrane protein of peroxisome assembly in a peroxisome-deficient mammalian cell mutant. Nature 350, 77-81.
56. Shimozawa, N. et al. (1992). A human gene responsible for Zellweger syndrome that affects peroxisome assembly. Science 239, 1536-1538.
57. Berteaux-Lecellier, V. et al. (1995). A nonmammalian homolog of the PAF1 gene (Zellweger syndrome) discovered as a gene involved in caryogamy in the fungus Podospora anserina. Cell 81, 1043-1051.
58. Waterham, H. R., de Vries, Y., Russell, K. A., Xie, W., Veenhuis, M. and Cregg, J. M. (1996). The Pichia pastoris PER6 gene product is a peroxisomal integral membrane protein essential for peroxisome biogenesis and has sequence similarity to the Zellweger syndrome protein PAF-1. Mol. Cell. Biol. 16, 2527-2536.
59. Tsukamoto, T., Shimozawa, N. and Fujiki, Y. (1994). Peroxisome assembly factor 1: nonsense mutation in a peroxisome-deficient Chinese hamster cell mutant and deletion analysis. Mol. Cell. Biol. 14, 5458-5465.
60. Kalish, J. E., Theda, C., Morrell, J. C., Berg, J. M. and Gould, S. J. (1995). Formation of the peroxisomal lumen is abolished by loss of Pichia pastoris Pas7p, a zinc-binding integral membrane protein of the peroxisome. Mol. Cell. Biol. 15, 6406-6419.
61. Kalish, J. E. et al. (1996). Characterization of a novel component of the peroxisomal protein import apparatus using fluorescent peroxisomal proteins. EMBO J. 15, 3275-3285.
62. Eitzen, G. A. et al. (1995). The Yarrowia lipolytica gene PAY2 encodes a 42-kDa peroxisomal integral membrane protein essential for matrix protein import and peroxisome enlargement but not for peroxisome proliferation. J. Biol. Chem. 270, 1429-1436.
63. Höhfeld, J., Veenhuis, M. and Kunau, W.-H. (1991). PAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane essential for peroxisome biogenesis. J. Cell Biol. 114, 1167-1178.
64. Baerends, R. J. S. et al. (1996). The Hansenula polymorpha PER9 gene encodes a peroxisomal membrane protein essential for peroxisome assembly and integrity. J. Biol. Chem. 271, 8887-8894.
65. Waterham, H. R. et al. (1994). The Hansenula polymorpha PER1 gene is essential for peroxisome biogenesis and encodes a peroxisomal matrix protein with both carboxy-and amino-terminal targeting signals. J. Cell Biol. 127, 737-749.
66. Liu, H., Tan, X., Russell, K. A., Veenhuis, M. and Cregg, J. M. (1995). PER3, a gene required for peroxisome biogenesis in Pichia pastoris, encodes a peroxisomal membrane protein involved in PTS1-and PTS2-protein import. J. Biol. Chem. 270, 10940-10951.
67. Glover, J. R., Andrews, D. W. and Rachubinski, R. A. (1994). Saccharomyces cerevisiae peroxisomal thiolase is imported as a dimer. Proc. Natl Acad. Sci. USA 191, 10541-10545.
68. McNew, J. A. and Goodman, J. M. (1994). An oligomeric protein is imported into peroxisomes in vivo. J. Cell Biol. 127, 1245-1257.
69. Häusler, T., Stierhof, Y.-D., Wirtz, E. and Clayton, C. (1996). Import of a DHFR hybrid protein into glycosomes in vivo is not inhibited by the folate-analogue aminopterin. J. Cell Biol. 132, 311-324.
70. Walton, P. A., Gould, S. J., Feramisco, J. R. and Subramani, S. (1992). Transport of microinjected proteins into peroxisomes of mammalian cells: inability of Zellweger cell lines to import proteins with the SKL tripeptide peroxisomal targeting signal. Mol. Cell. Biol. 12, 531-541.
71. Walton, P. A., Hill, P. E. and Subramani, S. (1995). Import of stably folded proteins into peroxisomes. Mol. Biol. Cell. 6, 675-683.
72. van der Leij, I., Franse, M. M., Elgersma, Y., Distel, B. and Tabak, H. F. (1993). PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 90, 11782-11786.
73. Heyman, J. A., Monosov, E. and Subramani, S. (1994). Role of the PAS1 gene of Pichia pastoris in peroxisome biogenesis. J. Cell Biol. 127, 1259-1273.
74. Voorn-Brouwer, T., van der Leij, I., Hemrika, W., Distel, B. and Tabak, H. F. (1993). Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1216, 325-328.