Intracellular signalling: Turning down G-protein signals

Current Biology

Volumn 7, Issue 1, 1997, Pages

  Neer, Eva J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031025382     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00014-5     Document Type: Review

References (11)

1. Neer EJ: Heterotrimeric G proteins: organizers of transmembrane signals. Cell 1995, 80:249-257.
2. Dohlman HG, Song J, Ma D, Courchesne WE, Thorner J: Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein α subunit). Mol Cell Biol 1996, 16:5194-5209.
3. Koelle MR, Horvitz HR: EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell 1996, 84:115-125.
4. i3, is a member of a protein family with a highly conserved core domain. Proc Natl Acad Sci USA 1995, 92:11916-11920.
5. Siderovski DP, Hessel A, Chung S, Mak TW, Tyers M: A new family of regulators of G-protein-coupled receptors? Curr Biol 1996, 6:211-212.
6. Druey KM, Blumer KJ, Kang VH, Kehrl JH: Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature 1996, 379:742-746
7. i subfamily of G protein α subunits. Cell 1996, 86:445-452.
8. Watson N, Linder ME, Druey KM, Kehrl JH, Blumer KJ: RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits. Nature 1996, 383:172-175.
9. i GTPase activity. Nature 1996, 383:175-177.
10. Berman DM, KozasaT, Gilman AG: The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis. J Biol Chem, in press.
11. Mittal R, Ahmadian MR, Goody RS, Wittinghofer A: Formation of a transition-state analog of the Ras GTPase reaction by Ras-GDP, tetrafluoroaluminate, and GTPase-activating proteins. Science 1996, 273:115-117.