Pharmacokinetic evaluation of liposomal encapsulated ampicillin in male and female rats

Biopharmaceutics and Drug Disposition

Volumn 18, Issue 4, 1997, Pages 279-292

  Pardue, Roseline L ^a   White, Catherine A ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

ampicillin; disposition; gender; liposomal encapsulated

Indexed keywords

AMPICILLIN; LIPOSOME;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG TISSUE LEVEL; ENCAPSULATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PHARMACOKINETICS; RAT; SEX DIFFERENCE;

AMPICILLIN; ANIMALS; DRUG CARRIERS; FEMALE; LIPOSOMES; MALE; PENICILLINS; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; TISSUE DISTRIBUTION;

EID: 0031006316     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199705)18:4<279::AID-BDD989>3.0.CO;2-G     Document Type: Article

References (31)

1. F. Emmen and G. Storm, Liposomes in treatment of infectious diseases. Pharm. Week. Sci. Edn, 9, 162-170 (1987).
2. C. E. Swenson, M. C. Popescu and R. S. Ginsberg, Preparation and use of liposomes in the treatment of microbial infections. Crit. Rev. Microbiology, 15, s1-s31 (1988).
3. C. R. Alving, E. A. Steck, W. L. Hanson, P. S. Loizeaux, W. L. Chapman and V. B. Waits, Improved therapy of experimental leishmaniasis by use of a liposome-encapsulated antimonial drug. Life Sci., 22, 1021-1026 (1978).
4. G. Poste, C. Bucana, A. Raz, P. Bugelski, R. Kirsh and I. J. Fidler, Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery. Cancer Res., 42, 1412-1422 (1982).
5. P. Pirson, R. Steiger and A. Trouet, The disposition of free and liposomally encapsulated antimalarial primaquine in mice. Biochem. Pharmacol., 31, 3501-3507 (1982).
6. R. L. Juliano and D. Stamp, Pharmacokinetics of liposome-encapsulated anti-tumor drugs. Biochem. Pharmacol., 27, 21-27 (1978).
7. R. M. Abra and C. A. Hunt, Liposome disposition in vivo III. Dose and vesicle-size effects. Biochim. Biophys. Acta, 666, 493-497 (1981).
8. T. Tadakuma, N. Ikewaki, T. Yasuda, M. Tsutsumi, S. Saito and K. Saito, Treatment of experiment Salmonellosis in mice with streptomycin entrapped in liposomes. Antimicrob. Agents Chemother., 28, 28-32 (1985).
9. R. M. Fielding, P. C. Smith, L. H. Wang, J. Porter and L. S. Guo, Comparative pharmacokinetics of amphotericin B after administration of a novel colloidal delivery system, ABCD, and a conventional formulation to rats. Antimicrob. Agents Chemother., 35, 1208-1213 (1991).
10. M. Magallanes, J. Dijkstra and J. Fierer, Liposome-incorporated ciprofloxacin in treatment of murine Salmonellosis. Antimicrob. Agents Chemother., 37, 2293-2297 (1993).
11. R. J. Pattisapu, D. A. Ashtekar, N. Ghori, J. A. Goldstein, R. J. Debs and N. Duzgunnes, Chemotherapeutic potential of free and liposome encapsulated streptomycin against experimental Mycobacterium avium complex infections in beige mice. J. Antimicrob. Chemother., 28, 425-435 (1991).
12. J. Lautersztain, R. Perez-Soler, J. Turpin, A. R. Khokhar, Z. H. Siddik, S. Schmidt and G. Lopez-Berestein, Cellular pharmacology of liposomal cis-Bis-neodecanoato-trans-R, R-1,2-diaminocyclohexaneplatinum (II) in mouse resident peritoneal macrophages, Kupffer cells, and hepatocytes. Cancer Res., 48, 1300-1306.
13. K. M. Wasan and G. Lopez-Berenstein, The influence of serum lipoproteins on the pharmacokinetics and pharmacodynamics of lipophilic drugs and drug carriers. Arch. Med. Res., 24, 1-7 (1993).
14. D. V. Devine, K. Wong, K. Serrano, A. Chonn and P. R. Cullis, Liposome-complement interactions in rat serum: implications for liposome survival studies. Biochim. Biophys. Acta, 1191, 43-51 (1994).
15. K. M. Wasan and G. Lopez-Berenstein, Modification of amphotericin B's therapeutic index by increasing its association with serum high-density lipoproteins. Ann. N.Y. Acad. Sci., 730, 93-106.
16. W. Patsch, K. Kim, W. Wiest and G. Schonfeld, Effects of sex hormones on rat lipoproteins. Endocrinology, 107, 1085-1094 (1980).
17. R. R. C. New, Liposomes: a Practical Approach - Preparation of MLVs by Handshaking Method, 1992, pp. 37-39.
18. J. L. Fox and M. L. Lamson, RSTRIP: Pharmacokinetic Data Stripping/Least Squares Parameter Optimization, Version 2, MicroMath, Salt Lake City, UT, 1982.
19. C. M. Metzler, G. L. Elfring, and A. J. McEwen, Package of computer programs for pharmacokinetic modeling. Biometrics, 30, 562-563 (1974).
20. M. Gibaldi and D. Perrier, Pharmacokinetics, 2nd edn, Dekker, New York, 1982.
21. H. William, Microbiological assay: an introduction to quantitative principles and evaluation, Academic, New York, 1977.
22. W. R. Perkins et al., The determination of liposome captured volume. Chem. Phys. Lipids, 64, 197-217 (1993).
23. M. C. Nacucchio, M. J. Gatto Bellora, D. O. Sordelli and M. D'Aquino, Enhanced liposome-mediated activity of piperacillin against Staphylococci. Antimicrob. Agents Chemother., 27, 137-139 (1985).
24. C. A. White, R. L. Pardue, C. Huang and J. Warren, Chronobiological evaluation of the active biliary and renal secretion of ampicillin. Chronobiol. Int., 12, 410-418 (1995).
25. C. A. White, L. Gong, D. Liang and K. Kumi, Biliary elimination of liposomal encapsulated ampicillin. J. Pharm. Sci., submitted.
26. J. Dijkstra, M. Van Galen, D. Regts and G. Scherphof, Uptake and processing of liposomal phospholipids by Kupffer cells in vitro. Eur. J. Biochem., 148, 391-397 (1985).
27. W. R. Gillespie, Simple methods for estimation of mean residence time and steady-state volume of distribution from continuous-infusion data. Pharm. Res., 8, 254-258.
28. A. Sa'ad, P. Roberts, L. E. Bolcsak, C. E. Swenson, A. S. Janoff and W. R. Ravis, Pharmaco-kinetic modeling of liposomal gentamicin (MAITEC®) in rats. J. Pharm. Sci., 11, s418 (1994).
29. R. Juliano and D. Stamp, The effect of particle size and charge on the clearance rates of liposomes and liposome-encapsulated drugs. Biochim. Biophys. Res. Commun., 63, 651-656 (1975).
30. S. Vemuri, C.-D. Yu, J. S. deGroot and N. Roosdorp, In vitro interaction of sized and unsized liposome vesicles with high density lipoprotein. Drug Dev. Ind. Pharm., 16, 1579-1584 (1990).
31. J. Senior and G. Gregoriadis, Stability of small unilamellar liposomes in serum and clearance from circulation: the effect of the phospholipid and cholesterol components. Life Sci., 30, 2123-2136 (1982).