Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (ii) in mouse resident peritoneal macrophages, kupffer cells, and hepatocytes

Cancer Research

Volumn 48, Issue 5, 1988, Pages 1300-1306

  Lautersztain, Julio ^a   Perez Soler, Roman ^a   Turpin, Jim ^a   Khokhar, Abdul R ^a   Siddik, Zahid H ^a   Schmidt, Karmen ^a   Lopez Berestein, Gabriel ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; LIPOSOME;

ANIMAL CELL; ANIMAL EXPERIMENT; DRUG TISSUE LEVEL; INTRAVENOUS DRUG ADMINISTRATION; KUPFFER CELL; LIVER CELL; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; ULTRASTRUCTURE;

ANIMAL; ANTINEOPLASTIC AGENTS; IN VITRO; KUPFFER CELLS; LIPOSOMES; LIVER; MACROPHAGES; MALE; MICE; ORGANOPLATINUM COMPOUNDS; PLATINUM; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023841264     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Salem, P. A., Hall, S. W., Benjamin, R. S., Murphy, W. K., Wharton, J. T., and Bodey, G. P. Clinical Phase I-II study of cis-dichlorodiammineplatinum (II) given by continuous iv. infusion. Cancer Treat. Rep., 62: 1553-1555, 1978.
2. Legha, S. S., Benjamin. R. S., McKay, B., Ewer, M. S., Wallace, S., Valdivieso, M., Rasmussen, S. L., Blumenschein, G. R., and Freireich, E. J. Reduction of doxorubicin cytotoxicity by prolonged continuous intravenous infusion. Ann. Intern. Med., 96: 133-139, 1982.
3. Rose, W. C., and Schurig, W. Preclinical antitumor and toxicologic profile of carboplatin. Cancer Treat Rev., 12(suppl A),: 1-19, 1985.
4. Ozols, R. F., Ostchega, Y., Curt, G., and Young, R. C. High dose carboplatin in refractory ovarian cancer patients. J. Clin. Oncol., 5: 197-201, 1987.
5. Burchenal, J. H., Kalaher, K., O'Toole, T., and Chisolm, J. Lack of cross resistance between certain platinum coordination compounds in mouse leukemia. Cancer Res., 37: 3455-3457, 1977.
6. Hill, J. M., Loeb, E., Pardue, A., Khan, A., King, J. S., Aleman, C., and Hill, N. O. Platinum analogs of clinical interest. Cancer Treat. Rep., 63: 1509-1513, 1979.
7. Lopez-Berestein, G., Kasi, L., Rosenblum, M. G., Haynie, T., Jahns, M., Glen, H., Mehta, R., Mavligit, G. M., and Hersh, E. M. Clinical pharmacology of 99mTc labeled liposomes in patients with cancer. Cancer Res., 44: 375-378, 1984.
8. Forssen, E. A., and Tokes, Z. A. Use of anionic liposomes for the reduction of chronic doxorubicin cardiotoxicity. Proc. Natl. Acad. Sci. USA, 78: 1873-1877, 1981.
9. Gabizon, A., Goren, P., Fuks, Z., Barenholz, Y., Dagan, A., and Meshover, A. Enhancement Of Adriamycin deliveryto liver metastatic cells with increased tumoricidal effect using liposomes as drug carriers. Cancer Res., 43: 4730-4735, 1983.
10. Freise, J., Mueller, W. H., Lagerstedt, P., and Schmoll, H. J. Pharmacokinetics of liposome-encapsulated cisplatin in rats. Arch. Int. Pharmacodyn. Ther., 258: 182-186, 1982.
11. Perez-Soler, R., Khokhar, A. R., and Lopez-Berestein, G. Development of lipophilic cisplatin analogs encapsulated in liposomes. In: G. Gregoriadis (ed.), Liposomes as Drug Carriers Trends and Progress. In press, 1987.
12. Perez-Soler, R., Khokhar, A. R., Hacker, M. P., and Lopez-Berestein, G. Toxicity and antitumor activity of cis-bis cyclopentene-carboxylato-l, 2-diaminocyclohexaneplatinum (II) enacapsulatedin multilamellar vesicles. Cancer Res., 46: 6269-6273, 1986.
13. Bowen, E., Vander Visgh, W. J. F., Nauta, M. M., Schluper, H. M. M., and Pinedo, H. M. Comparative activity and distribution studies of five platinum analoguesin nudemice bearinghuman ovarian carcinoma xenografts. Cancer Res., 45: 86-90, 1985.
14. Metcalfe, S. A., Cain, K., and Hill, B. T. Possible mechanisms for differences in sensitivityto d. cplatinum in human prostate cell lines. Cancer Lett., 31: 163-165, 1986.
15. Eicholtz-Wirth, H., and Hietel, B. The relationship between cisplatin sensitivity and drug uptake into mammalian cells in vitro. Br. J. Cancer, 54: 239-243, 1986.
16. Lautersztain, J., Perez-Soler, R., Khokhar, A. R., Newman, R. A., and Lopez-Berestein, G. Pharmacokinetics and tissue distribution of liposome-encapsulated cis-bis-N-decyliminodiacetato-l, 2-diaminocyclohexane-platinum(II). Cancer Chemother. Pharmacol., 18:93-97, 1986.
17. Perez-Soler, R., Khokhar, A. R., and Lopez-Berestein, G. Treatment and prophylaxis of experimental liver metastases of M5076 reticulosarcoma with cis-bis-neodecanoato-trans-R, R-1, 2-diaminocyclohexaneplatinum(II) encapsulatedin multilamellar vesicles.Cancer Res., 47: 6462-6466, 1987.
18. Drewinko, B., Yank, L. Y., Khohkar, A. R., Lautersztain, J., and Perez-Soler, R. Reversal of resistance to cisplatin by treatment with liposome trapped cis-bis-neodecanoato-trans-R, R-1, 2-diaminocyclohexaneplatinum (II) (Abstract 1247). Proc. AACR, 28: 315, 1987.
19. Khokhar, A. R., Hacker, M. P., Mc Cormack, J. J., and Krakoff, I. H. The synthesis and antitumor properties of a series of water soluble carboxylato I., 2-diaminocyclohexane-platinum (II) complexes. Inorganic Chemo. Acta (Bioniorg Section), 108: 63-66, 1985.
20. Pulford, K., and Souhami, R. L. Cell division and giant cell formation in Kupffer cell cultures. Clin. Exp. Immunol., 42: 67-76, 1980.
21. Zahlten, R. N., Hagler, H. K., Neitek, M. E., and Day, J. Morphological characterization of Kupifer and endothelial cells of rat liver isolated by counterflow elutriation. Gastroenterology, 75:80-87, 1978.
22. Mosman, T. Rapid colonmetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol., 65: 55-63, 1983.
23. Pera Jr., M. F., and Harder, H. C. Analysis for platinum in biological material by flameless atomic absorption spectrophotometry. Clin. Chem., 23(7):1245-1249, 1977.
24. Karnovsky, M. J. A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy. J. Cell. Biol., 27: 137A-138A 1965.
25. Hsu, M. J., and Juliano, R. L. Interactions of liposomes with the reticulo endothelial system I: Nonspecific and receptor mediated uptake Of liposomes by mouse peritoneal macrophages. Biochim. Biophys. Acta., 720:411-419, 1982.
26. Mehta, K., Lopez-Berestein, G., Hersh, E. M., and Juliano, R. L. Uptake of liposomes and liposome encapsulated muramyl dipeptide by human peripheral blood monocytes. J. Reticuloend. Soc., 35: 155-164, 1982.
27. Cudd, A., Labbe, H., Gervais, M., and Nicolau, C. Liposomes injected intravenously into mice associate with liver mitochondria. Biochem. Biophys. Acta., 774: 169-180, 1984.
28. Dijkstra, J., VanGalen, W. J. M., Hulstaert, C. E., Kalicharan, P., Roerdink, F. H., and Scherphof, G. L. Interaction of liposomes with Kupffer cells in vitro. Exp. Cell. Res., 150: 161-176, 1984.
29. Roerdink, F. H., Dijkstra, J., Spanjer, H. H., and Scherphof, G. L. Interaction of liposomes with hepatocytes and Kupffer cells in vivo and in vitro. Biochem. Soc. Trans., 12: 335-336, 1984.
30. Roerdink, F. H., Dijkstra, J., Hartman, G., Bolscher, B., and Scherphof, G. The involvement of parenchymal, Kupifer and endothelialliver cells in the hepatic uptake of intravenously injected liposomes. Effects of lanathanum and gadolinium salts. Biochim. Biophys. Acta., 677: 79-89, 1981.
31. Scherphof, G., Roerdink, F., Dijkstra, J., Ellens, H., de Zanger, R., and Wisse, E. Uptake of liposomes by rat and mouse hepatocytes and Kupifer cells. Biol. Cell., 47: 47-58, 1983.