Changes in E2F DNA-binding activity during induced erythroid differentiation

Cell Growth and Differentiation

Volumn 7, Issue 1, 1996, Pages 31-42

  Richon, Victoria M ^a   Venta Perez, Gisela ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; HEXAMETHYLENEBISACETAMIDE; HISTONE H1; MESSENGER RNA; PROTAMINE KINASE; RNA POLYMERASE; TRANSCRIPTION FACTOR E2F;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA BINDING; DNA PROTEIN COMPLEX; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ACETAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CARRIER PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL NUCLEUS; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; E2F4 TRANSCRIPTION FACTOR; GROWTH INHIBITORS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MICE; NUCLEAR PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P107; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA; MURINAE;

EID: 0030053859     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (68)

1. Marks, P. A., and Rifkind, R. A. Erythroleukemic differentiation. Annu. Rev Biochem., 47: 419-448, 1978.
2. Kaelin, W. G., Krek, W., Sellers, W. R., DeCaprio, J. A , Ajchanbaum, F., Fuchs, C. S., Chittenden, T., Li, Y., Farnham, P J., Blanar, M. A., Livingston, D M., and Flemington, E K Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell, 70: 351-364, 1992
3. Helin, K , Lees, J A., Vidal, M., Dyson, N., Harlow, E., and Fattaey, A. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell, 70: 337-349, 1992.
4. Shan, B., Zhu, X., Chen, P-L., Durfee, T., Yang, Y., Sharp, D , and Lee, W-H Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol. Cell. Biol., 12: 5620-5631, 1992.
5. Kovesdi, I., Reichel, R., and Nevins, J. R Identification of a cellular transcription factor involved in E1A trans-activation. Cell, 45: 219-228, 1986.
6. Bandara, L. R., Buck, V. M., Zamanian, M., Johnston, L. H., and La Thangue, N. B. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F EMBO J., 12: 4317-4324, 1993.
7. Girling, R., Partridge, J. F., Bandara, L R , Burden, N., Totty, N. F., Hsuan, J. J , and La Thangue, N. B. A new component of the transcription factor DRTF1/E2F. Nature (Lond.), 362: 83-87, 1993.
8. Helin, K , Wu, C., Fattaey, A., Lees, J., Dynlacht, B., Ngwu, C., and Harlow, E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative transactivation. Genes & Dev., 7: 1850-1861, 1993.
9. Krek, W., Livingston, D. M., and Shirodkar, S. Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science (Washington DC), 262: 1557-1560, 1993.
10. Ivey-Hoyle, M., Conroy, R., Huber, H., Goodhart, P., Oliff, A., and Heinbrook, D. C. Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol Cell. Biol., 13: 7802-7812, 1993.
11. Lees, J. A., Saito, M., Vidal, M., Valentine, M., Look, T., Harlow, E., Dyson, N., and Helin, K. The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell Biol., 13: 7813-7825, 1993.
12. Ginsberg, D., Vairo, G., Chittenden, T., Xiao, Z-X., Xu, G., Wynder, K. L , DeCaprio, J. A., Lawrence, J. B., and Livingston, D. M. E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes & Dev., 8: 2665-2679, 1994.
13. Beijerbergen, R. L., Kerkhoven, R. M., Zhu, L., Carlee, L., Voorhoeve, P. M., and Bernards, R. E2F4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes & Dev., 8: 2660-2690, 1994.
14. Sardet, C., Vidal, M., Cobrinik, D., Geng, Y., Onufryk, C., Chen, A., and Weinberg, R. A. E2F-4 and E2F-5, two members of the E2F family, are expressed in early phases of the cell cycle. Proc. Natl. Acad. Sci. USA, 92: 2403-2407, 1995.
15. Bandara, L. R., Lam, E. W-R., Sorensen, M., Zamanian, M., Girling, R., and La Thangue, N. B. DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRB and the adenovirus E4 orf 6/7 protein. EMBO. J., 13: 3104-3114, 1994.
16. Wu, C-L., Zukerberg, L. R., Ngwu, C., Harlow, E., and Lees, J. A. In vivo association of E2F and DP family proteins. Mol. Cell. Biol., 15: 2536-2546, 1995.
17. Nevins, J. R. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (Washington DC), 258: 424-429, 1992.
18. Lam, E. W-F., and Watson, R. J. An E2F-binding site mediates cell cycle-regulated repression of mouse B-myb transcription. EMBO J., 12: 2705-2713, 1994.
19. Bagchi, S., Weinmann, R., and Raychaudhuri, P. The retinoblastoma protein copurifies with E2F-1, an E1A-regulated inhibitor of the transcription factor E2F. Cell, 65: 1063-1072, 1991.
20. Bandara, L. R., and La Thangue, N. B. Adenovirus E1A prevents the retinoblastoma gene product from complexing with a cellular transcription Factor. Nature (Lond.), 351: 494-497, 1991.
21. Chellappan, S. P., Hiebert, S , Mudryj, M., Horowitz, J. M., and Nevins, J. R. The E2F transcription factor is a cellular target for the Rb protein. Cell, 65: 1053-1061, 1991.
22. Chittenden, T , Livingston, D. M., and Kaelin, W. G. The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell, 65: 1073-1082, 1991.
23. Cao, L., Faha, B., Dembski, M., Tsai, L-H., Harlow, E., and Dyson, N. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature (Lond.), 355: 176-179, 1992
24. Lees, E., Faha, B , Dulic, V., Reed, S. I., and Harlow, E. Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes & Dev., 6: 1874-1885, 1992.
25. Shirodkar, S., Ewen, M., DeCaprio, J. A., Morgan, J., Livingston, D M., and Chittenden, T The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell, 68: 157-166, 1992.
26. Cobrinik, D., Whyte, P., Pepper, D. S., Jackson, T., and Weinberg, R. A. Cell cycle-specific association of E2F with the p130 E1A-binding domain. Genes & Dev., 7: 2392-2404, 1993.
27. Li, Y., Graham, C., Lacy, S., Duncan, A. M. W., and Whyte, P. The adenovirus E1A-associated 130-kD is encoded by a member of the retinoblastoma gene family and physically interacts with cycling A and E Genes & Dev., 7: 2366-2377, 1993.
28. Hannon, G. J., Demetrick, D., and Beach, D. Isolation of the Rb-related p130 through its interactions with cdk2 and cyclins. Genes & Dev., 7: 2378-2391, 1993.
29. Hamel, P. A., Gill, R. M., Phillips, R. A., and Gallie, B. L. Transcriptional repression of the E2-containing promoters EllaE, c-myc and RB1 by the product of the RB1 gene. Mol. Cell. Biol., 12: 3431-3438, 1992.
30. Hiebert, S. W., Chellappan, S. P., Horowitz, J. M., and Nevins, J. R. The interaction of pRb with E2F inhibits the transcriptional activity of E2F. Genes & Dev., 6: 177-185, 1992.
31. Weintraub, S. J., Prater, C. A., and Dean, D. C. Retinoblastoma protein switches the E2F site from positive to negative element. Nature (Lond.), 353: 259-261, 1992.
32. Zamanian, M., and La Thangue, N. B. Adenovirus E1A prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor. EMBO J., 11: 2603-2610, 1992.
33. Schwartz, J. K., Devoto, S. H , Smith, E. J., Chellappan, S. P., Jakoi, L., and Nevins, J. R. Interactions of the p107 and Rb proteins with E2F during the cell proliferation response. EMBO. J., 12: 1013-1020, 1993.
34. Zamanian, M., and La Thangue, N. B. Transcriptional repression by the Rb-related protein p107. Mol. Biol. Cell., 4: 389-396, 1993.
35. Zhu, L., van den Heuvel, S., Helin, K., Fattaey, A., Ewen, M., Livingston, D., Dyson, N., and Harlow, E. inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes & Dev., 7: 1111-1125, 1993.
36. Pagano, M., Draetta, G., and Jansen-Durr, P. Association of cdk2 kinase with the transcription factor E2F during the S phase. Science (Washington DC), 255: 1144-1147, 1992.
37. Chittenden, T., Livingston, D. M., and DeCaprio, J. A. Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol. Cell. Biol., 13: 3975-3983, 1993.
38. Gusella, J. F., Geller, R., Clarke, B., Weeks, V., and Housman, D. Commitment to erythroid differentiation by Friend erythroleukemia cells: a stochastic analysis. Cell, 9: 221-229, 1976.
39. Fibach, E., Reuben, R. C., Rifkind, R. A., and Marks, P. A. Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells. Cancer Res., 37: 440-444, 1977.
40. Richon, V. M., Michaeli, J., Rifkind, R. A., and Marks, P A. Erythroleukemia Cells. Molecular and Cellular Approaches to the Control of Proliferation and Differentiation, pp. 243-267. New York: Academic Press, 1992.
41. 1/early S. Proc. Natl. Acad. Sci. USA, 76: 4511-4515, 1979.
42. CDC2kinase activity and cyclin A during induced differentiation of murine erythroleukemia cells. Cell Growth & Differ., 3: 377-383, 1992.
43. Richon, V. M., Rifkind, R A., and Marks, P. A. Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells Cell Growth & Differ., 3: 413-420, 1992.
44. Kiyokawa, H., Richon, V. M., Rifkind, R. A., and Marks, P A. Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells. Mol. Cell. Biol., 74: 7195-7203, 1994.
45. Bagchi, S., Raychaudhun, R., and Nevins, J. R. Adenovirus E1A can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation Cell, 62: 659-669, 1990.
46. Dyson, N., Dembski, M., Fattaey, A., Ngwu, C., Ewen, M., and Helin, K. Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB associated E2F-1. J. Virol., 67: 7641-7647, 1993.
47. Li, Y., Slansky, J. E. Myers, D. J., Drinkwater, N. R., Kaelm, W. G., and Farnham, P. J Cloning, chromosomal location, and characterization of mouse E2F1. Mol. Cell Biol., 14: 1861-1869, 1994.
48. La Thangue, N. B., and Rigby, P. W An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell, 49: 507-513, 1987.
49. Reichel, R. R. Regulation of E2F/cyclin A-containing complex upon retinoic acid-induced differentiation of teratocarcinoma cells. Gene Express., 2: 259-271, 1992.
50. Hara, E., Okamoto, S., Makaka, S., Taya, Y., Sekiya, S., and Oda, K. Protein phosphorylation required for the formation of E2F complexes regulates N-myc transcription during differentiation of human embryonal carcinoma cells. Oncogene, 8: 1023-1032, 1993.
51. Shin, E. K., Shin, A., Paulding, C , Schaffhausen, B., and Yee, A. Multiple changes in E2F function and regulation occur upon muscle differentiation. Mol. Cell. Biol., 15: 2252-2262, 1995.
52. Ewen, M. E. The cell cycle and the retinoblastoma protein family. Cancer & Metastasis Rev., 13: 45-66, 1994.
53. Krek, W., Ewen, M. E., Shirodkar, S., Arany, Z., Kaelin, W. G , and Livingston, D M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase Cell, 78: 161-172, 1994.
54. Giri, J. G., Reuben, R. C., Rifkind, R. A., and Marks, P. A. DNA polymerase activities during induced differentiation in murine erythroleukemia cells. Exp. Cell Res., 132: 137-146, 1981.
55. Moore, A. L., and Wang, T. S-F. Down regulation of genes encoding DNA replication proteins during cell cycle exit. Cell Growth & Differ , 5: 485-494, 1994.
56. Ramsay, R. G., Ikeda, K., Rifkind, R. A., and Marks, P. A. Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes and cell division. Proc. Natl. Acad. Sci. USA, 83: 6849-6853, 1986.
57. Watson, R. J. Expression of the c-myb and the c-myc gene is regulated independently in differentiating mouse erythroleukemia cells by common processes of premature transcription arrest and increased mRNA turnover. Mol. Cell. Biol., 8: 3938-3942, 1988.
58. Meulia, T., Krumm, A., and Groudine, M. Distinct properties of c-myc transcriptional elongation are revealed in Xenopus oocytes and mammalian cells and by template titration Mol. Cell. Biol., 13. 5647-5658, 1993.
59. Cardoso, M. C., Leonhardt, H., and Nadal-Ginard, B. Reversal of terminal differentiation and control of DNA replication: cyclin A and cdk2 specifically localize at subnuclear site of DNA replication. Cell, 74: 979-992, 1993.
60. Amin, A. A., Murakami, Y., and Hurwitz, J. Initiation of DNA replication by simian virus 40 T antigen is inhibited by the p107 protein. J. Biol. Chem., 269: 7735-7743, 1994.
61. Chen, Z. X., Banks, J., Rifkind, R. A., and Marks, P. A. Inducer-mediated commitment of murine erythroleukemia cells to differentiation: a multistep process. Proc. Natl. Acad. Sci. USA, 79: 471-475, 1982.
62. Reuben, R. C., Wife, R. L., Breslow, R., Rifkind, R. A., and Marks, P. A. A new group of potent inducers of differentiation in murine erythroleukemia cells. Proc. Natl. Acad. Sci. USA, 73: 862-866, 1976
63. Terada, M , Fried, J., Nudel, U., Rifkind, R. A., and Marks, P. A. Transient inhibition of initiation of S phase associated with dimethyl sulfoxide induction of murine erythroleukemia cells to erythroid differentiation Proc. Natl Acad. Sci. USA, 74: 248-252, 1977.
64. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res., 11: 1475-1489, 1983.
65. Towbin, H., Staehelin, T., and Gordon, J. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76: 4350-4354, 1979.
66. Burnette, W. N. Western blotting: electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to unmodified nitrocellulose: a radiographic detection with antibody and radioiodinated protein A. Anal. Biochem., 112: 195-203, 1981.
67. 2 phases of the cell cycle and associated with cyclin A. Proc Natl. Acad. Sci. USA, 89: 2824-2828, 1992.
68. Melton, D. A., Krief, P. A , Rebagliati, M. R., Maniatis, T., Zinn, K., and Green, M. R. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res , 12: 7036-7056, 1984.