-
1
-
-
0025939057
-
Reversal effect of DM-9384 on scopolamine-induced acetylcholine depletion in certain regions of the mouse brain
-
Abe E (1991) Reversal effect of DM-9384 on scopolamine-induced acetylcholine depletion in certain regions of the mouse brain. Psychopharmacology 105:310-316
-
(1991)
Psychopharmacology
, vol.105
, pp. 310-316
-
-
Abe, E.1
-
2
-
-
0028177150
-
Effects of nefiracetam on deficits in active avoidance response and hippocampal cholinergic and monoaminergic dysfunctions induced by AF64A in mice
-
Abe E, Murai S, Saito H et al. (1994) Effects of nefiracetam on deficits in active avoidance response and hippocampal cholinergic and monoaminergic dysfunctions induced by AF64A in mice. J Neural Transm [Gen Sect] 95:179-193
-
(1994)
J Neural Transm [Gen Sect]
, vol.95
, pp. 179-193
-
-
Abe, E.1
Murai, S.2
Saito, H.3
-
3
-
-
0028596018
-
Cerebellar and brainstem circuits involved in classical eyeblink conditioning
-
Anderson BJ, Steinmetz JE (1994) Cerebellar and brainstem circuits involved in classical eyeblink conditioning. Rev Neurosci 5:251-273
-
(1994)
Rev Neurosci
, vol.5
, pp. 251-273
-
-
Anderson, B.J.1
Steinmetz, J.E.2
-
4
-
-
0021321761
-
Long-term potentiation on hippocampal synaptic transmission affects rate of behavioral learning
-
Berger TW (1984) Long-term potentiation on hippocampal synaptic transmission affects rate of behavioral learning. Science 224:627-630
-
(1984)
Science
, vol.224
, pp. 627-630
-
-
Berger, T.W.1
-
5
-
-
0000196748
-
Role of the hippocampus in classical conditioning of aversive and appetitive behaviors
-
Isaacson RL, Pribram KH (eds) Plenum Press, New York
-
Berger TW, Berry SD, Thompson RF (1986) Role of the hippocampus in classical conditioning of aversive and appetitive behaviors. In: Isaacson RL, Pribram KH (eds) The hippocampus, vol IV. Plenum Press, New York, pp 203-239
-
(1986)
The Hippocampus
, vol.4
, pp. 203-239
-
-
Berger, T.W.1
Berry, S.D.2
Thompson, R.F.3
-
6
-
-
8244253732
-
-
Betzing H, Biederman J, Materne C, Neuser V (1980) Pyrrolidin-2-on-1-ylacetic acid 2,6-dimethylanilide, process of preparation and pharmaceutical compositions containing them. German Patent No. DE 2924011
-
Betzing H, Biederman J, Materne C, Neuser V (1980) Pyrrolidin-2-on-1-ylacetic acid 2,6-dimethylanilide, process of preparation and pharmaceutical compositions containing them. German Patent No. DE 2924011
-
-
-
-
7
-
-
0030306522
-
On the cerebellum and classical conditioning
-
Daum I, Schugens MM(1996) On the cerebellum and classical conditioning. Cur Dir Psychol Sci 5:58-61
-
(1996)
Cur Dir Psychol Sci
, vol.5
, pp. 58-61
-
-
Daum, I.1
Schugens, M.M.2
-
8
-
-
0027210978
-
Nefiracetam (DM-9384) preserves hippocampal neural cell adhesion molecule-mediated memory consolidation process during scopolamine disruption of passive avoidance training in the rat
-
Doyle E, Regan CM, Shiotani T (1993) Nefiracetam (DM-9384) preserves hippocampal neural cell adhesion molecule-mediated memory consolidation process during scopolamine disruption of passive avoidance training in the rat. J Neurochem 61: 266-272
-
(1993)
J Neurochem
, vol.61
, pp. 266-272
-
-
Doyle, E.1
Regan, C.M.2
Shiotani, T.3
-
9
-
-
0021672436
-
Changes of dopamine metabolism by hypoxia and effect of nootropic drugs
-
Funk KF, Schmidt J (1984) Changes of dopamine metabolism by hypoxia and effect of nootropic drugs. Biomed Biochem Acta 11:1301-1304
-
(1984)
Biomed Biochem Acta
, vol.11
, pp. 1301-1304
-
-
Funk, K.F.1
Schmidt, J.2
-
10
-
-
0000727259
-
Characteristic of learning deficit induced by ibotenic acid lesion of the frontal cortex related with the nucleus basalis of Meynert in rats
-
Nagatsu T, Yoshida M (eds) Plenum Press, New York
-
Hara C, Ogawa N (1990) Characteristic of learning deficit induced by ibotenic acid lesion of the frontal cortex related with the nucleus basalis of Meynert in rats. In: Nagatsu T, Yoshida M (eds) Basic, clinical, and therapeutic aspects of Alzheimer's and Parkinson's disease, vol 1. Plenum Press, New York, pp 735-738
-
(1990)
Basic, Clinical, and Therapeutic Aspects of Alzheimer's and Parkinson's Disease
, vol.1
, pp. 735-738
-
-
Hara, C.1
Ogawa, N.2
-
11
-
-
0004892540
-
DM-9384, a pyrrolidone derivative, ameliorates basal forebrain lesion-induced amnesia and inhibits cycloheximide-induced decrease in the number of GABA and acetylcholine receptors
-
Nagatsu T, Yoshida M (eds) Plenum Press, New York
-
Kameyama T, Nabeshima T, Tohyama K et al. (1990) DM-9384, a pyrrolidone derivative, ameliorates basal forebrain lesion-induced amnesia and inhibits cycloheximide-induced decrease in the number of GABA and acetylcholine receptors. In: Nagatsu T, Yoshida M (eds) Basic, clinical, and therapeutic aspects of Alzheimer's and Parkinson's diseases, vol 2. Plenum Press, New York, pp 371-374
-
(1990)
Basic, Clinical, and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases
, vol.2
, pp. 371-374
-
-
Kameyama, T.1
Nabeshima, T.2
Tohyama, K.3
-
12
-
-
0027344055
-
Mammalian brain substrates of aversive classical conditioning
-
Lavond DG, Kim JJ, Thompson RF (1993) Mammalian brain substrates of aversive classical conditioning. Annu Rev Psychol 44:317-342
-
(1993)
Annu Rev Psychol
, vol.44
, pp. 317-342
-
-
Lavond, D.G.1
Kim, J.J.2
Thompson, R.F.3
-
13
-
-
0020585413
-
Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system
-
McKinney M, Coyle JT, Hedreen JC (1983) Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system. J Comp Neurol 217: 103-111
-
(1983)
J Comp Neurol
, vol.217
, pp. 103-111
-
-
McKinney, M.1
Coyle, J.T.2
Hedreen, J.C.3
-
14
-
-
0025039780
-
Oxiracetam increases the release of endogeneous glutamate from depolarized rat hippocampal slices
-
Marchi M, Besana E, Raiteri M (1990) Oxiracetam increases the release of endogeneous glutamate from depolarized rat hippocampal slices. Eur J Pharmacol 185:247-249
-
(1990)
Eur J Pharmacol
, vol.185
, pp. 247-249
-
-
Marchi, M.1
Besana, E.2
Raiteri, M.3
-
15
-
-
0027984961
-
Ameliorating effects of nefiracetam (DM-9384) on brain dysfunction
-
Nabeshima T (1994) Ameliorating effects of nefiracetam (DM-9384) on brain dysfunction. Drugs Today 30:357-379
-
(1994)
Drugs Today
, vol.30
, pp. 357-379
-
-
Nabeshima, T.1
-
16
-
-
0025309740
-
Effects on DM-9384 in a model of amnesia based on animals with GABA-ergic neuronal dysfunctions
-
Nabeshima T, Noda Y, Tohyama K, Itoh J, Kameyama T (1990) Effects on DM-9384 in a model of amnesia based on animals with GABA-ergic neuronal dysfunctions. Eur J Pharmacol 178:143-149
-
(1990)
Eur J Pharmacol
, vol.178
, pp. 143-149
-
-
Nabeshima, T.1
Noda, Y.2
Tohyama, K.3
Itoh, J.4
Kameyama, T.5
-
17
-
-
0026352310
-
Effects of DM-9384 and aniracetam on learning in normal and basal forebrain-lesioned rats
-
Nabeshima T, Ogawa S, Kameyama T, Shiotani T, Yoshiyuki T, Sakurai T, Hasegawa M, Hasegawa T (1991a) Effects of DM-9384 and aniracetam on learning in normal and basal forebrain-lesioned rats. Res Commun Psychol Psychiatr Behav 16:1-14
-
(1991)
Res Commun Psychol Psychiatr Behav
, vol.16
, pp. 1-14
-
-
Nabeshima, T.1
Ogawa, S.2
Kameyama, T.3
Shiotani, T.4
Yoshiyuki, T.5
Sakurai, T.6
Hasegawa, M.7
Hasegawa, T.8
-
18
-
-
0025328801
-
Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordizepoxide-induced amnesia in mice
-
Nabeshima T, Tohyama K, Kameyama T (1991b) Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordizepoxide-induced amnesia in mice. Pharmacol Biochem Behav 36: 233-236
-
(1991)
Pharmacol Biochem Behav
, vol.36
, pp. 233-236
-
-
Nabeshima, T.1
Tohyama, K.2
Kameyama, T.3
-
19
-
-
0011338313
-
DM-9384, a pyrrolidone derivative, protects the membrane dysfunction induced by deprivation of oxygen and glucose in guinea-pig hippocampal neurons in vitro
-
Abst
-
Nakamura J, Higashi H, Nishi S, Nakazawa Y (1991) DM-9384, a pyrrolidone derivative, protects the membrane dysfunction induced by deprivation of oxygen and glucose in guinea-pig hippocampal neurons in vitro. Biol Psychiatry 29 [11 Suppl]: Abst P-29-36
-
(1991)
Biol Psychiatry
, vol.29
, Issue.11 SUPPL.
-
-
Nakamura, J.1
Higashi, H.2
Nishi, S.3
Nakazawa, Y.4
-
20
-
-
0011340531
-
Possible involvement of the activation of calcium channel in the improving effects of nefiracetam (DM-9384) on scopolamine-induced impairment of performance in a passive avoidance task
-
Nakayama S, Yamada K, Shiotani T et al. (1994) Possible involvement of the activation of calcium channel in the improving effects of nefiracetam (DM-9384) on scopolamine-induced impairment of performance in a passive avoidance task. Jpn J Pharmacol 64[Suppl]: 353
-
(1994)
Jpn J Pharmacol
, vol.64
, Issue.SUPPL.
, pp. 353
-
-
Nakayama, S.1
Yamada, K.2
Shiotani, T.3
-
21
-
-
0024523079
-
Effects of N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl) acetamide (DM-9384) on learning and memory in rats
-
Sakurai T, Ojima H, Yamasaki T, Kojima H, Akashi A (1989) Effects of N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl) acetamide (DM-9384) on learning and memory in rats. Jpn J Pharmacol 50:47-53
-
(1989)
Jpn J Pharmacol
, vol.50
, pp. 47-53
-
-
Sakurai, T.1
Ojima, H.2
Yamasaki, T.3
Kojima, H.4
Akashi, A.5
-
22
-
-
0022576522
-
3H]acetylcholine in rat brain
-
3H]acetylcholine in rat brain. Life Sci 38:2111-2120
-
(1986)
Life Sci
, vol.38
, pp. 2111-2120
-
-
Schwartz, R.D.1
-
23
-
-
0026564189
-
Effects of nefiracetam, DM-9384 on amnesia and decrease in chilineacetyltransferase activity induced by cycloheximide
-
Shiotani T, Tohyama K, Murase K, Ishihara S-I, Kameyama T, Yamasaki T, Hatanaka S, Kojima H, Yoshiyuki T, Nabeshima T (1992) Effects of nefiracetam, DM-9384 on amnesia and decrease in chilineacetyltransferase activity induced by cycloheximide. J Neural Transm [Gen Sect] 90:103-111
-
(1992)
J Neural Transm [Gen Sect]
, vol.90
, pp. 103-111
-
-
Shiotani, T.1
Tohyama, K.2
Murase, K.3
Ishihara, S.-I.4
Kameyama, T.5
Yamasaki, T.6
Hatanaka, S.7
Kojima, H.8
Yoshiyuki, T.9
Nabeshima, T.10
-
24
-
-
0020568856
-
Altered activity in the hippocampus is more detrimental to classical conditioning than removing the structure
-
Solomon PR, Solomon SD, Vander Schaaf E, Perry HE (1983) Altered activity in the hippocampus is more detrimental to classical conditioning than removing the structure. Science 220:329-331
-
(1983)
Science
, vol.220
, pp. 329-331
-
-
Solomon, P.R.1
Solomon, S.D.2
Vander Schaaf, E.3
Perry, H.E.4
-
25
-
-
0022548113
-
Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in the rat brain: Relation to cholinergic nuclei and projections
-
Spencer DG Jr, Horvath E, Raber J (1986) Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in the rat brain: relation to cholinergic nuclei and projections. Brain Res 380:59-68
-
(1986)
Brain Res
, vol.380
, pp. 59-68
-
-
Spencer Jr., D.G.1
Horvath, E.2
Raber, J.3
-
26
-
-
0023181845
-
Interactions between oxiracetam, quaniracetam and scopolamine on behavior and brain acetylcholine
-
Spignoli G, Pepeu G (1987) Interactions between oxiracetam, quaniracetam and scopolamine on behavior and brain acetylcholine. Pharmacol Biochem Behav 27:491-495
-
(1987)
Pharmacol Biochem Behav
, vol.27
, pp. 491-495
-
-
Spignoli, G.1
Pepeu, G.2
-
27
-
-
0001797341
-
Brain substrates of aversive classical conditioning
-
Madden J IV (ed) Raven Press, New York
-
Steinmetz JE, Thompson RF (1991) Brain substrates of aversive classical conditioning. In: Madden J IV (ed) Neurobiology of learning, emotion and affect. Raven Press, New York, pp 97-120
-
(1991)
Neurobiology of Learning, Emotion and Affect
, pp. 97-120
-
-
Steinmetz, J.E.1
Thompson, R.F.2
-
28
-
-
0011291367
-
Disposition and metabolism of DM-9384, a cyclic GABA derivative, in the rat, dog, and monkey
-
Abstr 32.02.05
-
Sudo K, Hashimoto K, Fujimaki Y, Tachizawa H (1988) Disposition and metabolism of DM-9384, a cyclic GABA derivative, in the rat, dog, and monkey. Psychopharmacology 96 [Suppl.]: Abstr 32.02.05
-
(1988)
Psychopharmacology
, vol.96
, Issue.SUPPL.
-
-
Sudo, K.1
Hashimoto, K.2
Fujimaki, Y.3
Tachizawa, H.4
-
29
-
-
0028231217
-
Organization of memory traces in the mammalian brain
-
Thompson RF, Krupa DJ (1994) Organization of memory traces in the mammalian brain. Annu Rev Neurosci 17:519-549
-
(1994)
Annu Rev Neurosci
, vol.17
, pp. 519-549
-
-
Thompson, R.F.1
Krupa, D.J.2
-
30
-
-
0027209321
-
DM-9384, a new cognition-enhancing agent, increases the turnover of components of the GABAergic system in the rat cerebral cortex
-
Watabe S, Yamaguchi H, Ashida S (1993) DM-9384, a new cognition-enhancing agent, increases the turnover of components of the GABAergic system in the rat cerebral cortex. Eur J Pharmacol 238:303-309
-
(1993)
Eur J Pharmacol
, vol.238
, pp. 303-309
-
-
Watabe, S.1
Yamaguchi, H.2
Ashida, S.3
-
31
-
-
84989454036
-
Evaluation of cognition-enhancing drugs: Utility of the model system of eyeblink classical conditioning
-
Woodruff-Pak DS (1995) Evaluation of cognition-enhancing drugs: utility of the model system of eyeblink classical conditioning. CNS Drug Rev 1:107-128
-
(1995)
CNS Drug Rev
, vol.1
, pp. 107-128
-
-
Woodruff-Pak, D.S.1
-
32
-
-
0028352414
-
Nefiracetam (DM-9384): Effect on classical conditioning in older rabbits
-
Woodruff-Pak DS, Li Y-T (1994) Nefiracetam (DM-9384): effect on classical conditioning in older rabbits. Psychopharmacology 114:200-208
-
(1994)
Psychopharmacology
, vol.114
, pp. 200-208
-
-
Woodruff-Pak, D.S.1
Li, Y.-T.2
-
33
-
-
0029891416
-
The older rabbit as an animal model: Implications for Alzheimer's disease
-
Woodruff-Pak DS, Trojanowski JQ (1996) The older rabbit as an animal model: implications for Alzheimer's disease. Neurobiol Aging 17:283-290
-
(1996)
Neurobiol Aging
, vol.17
, pp. 283-290
-
-
Woodruff-Pak, D.S.1
Trojanowski, J.Q.2
-
34
-
-
0023092269
-
Classical conditioning in 3-, 30- and 45-month-old rabbits: Behavioral learning and hippocampal unit activity
-
Woodruff-Pak DS, Lavond DG, Logan CG, Thompson RF (1987) Classical conditioning in 3-, 30- and 45-month-old rabbits: behavioral learning and hippocampal unit activity. Neurobiol Aging 8:101-108
-
(1987)
Neurobiol Aging
, vol.8
, pp. 101-108
-
-
Woodruff-Pak, D.S.1
Lavond, D.G.2
Logan, C.G.3
Thompson, R.F.4
-
35
-
-
0027960924
-
The neurotropic compound, BMY 21502, and classical conditioning of the nictitating membrane response in young and older rabbits
-
Woodruff-Pak DS, Coffin JM, Papka M (1994b) The neurotropic compound, BMY 21502, and classical conditioning of the nictitating membrane response in young and older rabbits. Psychobiology 22:312-319
-
(1994)
Psychobiology
, vol.22
, pp. 312-319
-
-
Woodruff-Pak, D.S.1
Coffin, J.M.2
Papka, M.3
-
36
-
-
0028341821
-
Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits
-
Woodruff-Pak DS, Li Y-T, Kazmi A, Kem WR (1994a) Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits. Behav Neurosci 108:486-493
-
(1994)
Behav Neurosci
, vol.108
, pp. 486-493
-
-
Woodruff-Pak, D.S.1
Li, Y.-T.2
Kazmi, A.3
Kem, W.R.4
-
37
-
-
0030042148
-
Training to criterion in eyeblink classical conditioning in Alzheimer's disease. Down's syndrome with Alzheimer's disease, and healthy elderly
-
Woodruff-Pak DS, Romano S, Papka M (1996) Training to criterion in eyeblink classical conditioning in Alzheimer's disease. Down's syndrome with Alzheimer's disease, and healthy elderly. Behav Neurosci 110:22-29
-
(1996)
Behav Neurosci
, vol.110
, pp. 22-29
-
-
Woodruff-Pak, D.S.1
Romano, S.2
Papka, M.3
-
38
-
-
0031039999
-
Hippocampus in delay eyeblink classical conditioning: Essential for nefiracetam amelioration of leaning in older rabbits
-
in press
-
Woodruff-Pak DS, Li Y-T, Hinchliffe RM, Port RL (1997) Hippocampus in delay eyeblink classical conditioning: essential for nefiracetam amelioration of leaning in older rabbits. Brain Res (in press)
-
(1997)
Brain Res
-
-
Woodruff-Pak, D.S.1
Li, Y.-T.2
Hinchliffe, R.M.3
Port, R.L.4
-
39
-
-
0028297182
-
Enhancement of neuronal calcium channel currents by the nootropic agent, nefiracetam (DM-9384), in NG108-14 cells
-
Yoshii M, Watabe S (1994) Enhancement of neuronal calcium channel currents by the nootropic agent, nefiracetam (DM-9384), in NG108-14 cells. Brain Res 642:123-131
-
(1994)
Brain Res
, vol.642
, pp. 123-131
-
-
Yoshii, M.1
Watabe, S.2
|