메뉴 건너뛰기




Volumn 48, Issue 5 SUPPL. 6, 1997, Pages

Alzheimer's disease: Clinical implications of the apolipoprotein E genotype

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; APOLIPOPROTEIN E; NEUROPROTECTIVE AGENT; SELEGILINE; TACRINE;

EID: 0030970412     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.48.5_suppl_6.30s     Document Type: Article
Times cited : (43)

References (46)
  • 1
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late-onset families
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late-onset families. Science 1993;261:921-923.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 2
    • 0027327267 scopus 로고
    • Association of apolipoprotein E allele ∈4 with late-onset familial and sporadic Alzheimer's disease
    • Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele ∈4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472.
    • (1993) Neurology , vol.43 , pp. 1467-1472
    • Saunders, A.M.1    Strittmatter, W.J.2    Schmechel, D.3
  • 4
    • 0028301820 scopus 로고
    • Apolipoprotein E: Risk factor for Alzheimer disease
    • Tsai M-S, Tangalos EG, Petersen RC, et al. Apolipoprotein E: risk factor for Alzheimer disease. Am J Hum Genet 1994;54: 643-649.
    • (1994) Am J Hum Genet , vol.54 , pp. 643-649
    • Tsai, M.-S.1    Tangalos, E.G.2    Petersen, R.C.3
  • 5
    • 0028170013 scopus 로고
    • Apolipoprotein E-∈4 allele doses in late-onset Alzheimer's disease
    • Lucotte G, Turpin J-C, Landais P. Apolipoprotein E-∈4 allele doses in late-onset Alzheimer's disease. Ann Neurol 1994;36: 681-682.
    • (1994) Ann Neurol , vol.36 , pp. 681-682
    • Lucotte, G.1    Turpin, J.-C.2    Landais, P.3
  • 6
    • 0027339923 scopus 로고
    • The apolipoprotein ∈4 allele in patients with Alzheimer's disease
    • Mayeux R, Stern Y, Ottman R, et al. The apolipoprotein ∈4 allele in patients with Alzheimer's disease. Ann Neurol 1993; 34:752-754.
    • (1993) Ann Neurol , vol.34 , pp. 752-754
    • Mayeux, R.1    Stern, Y.2    Ottman, R.3
  • 7
    • 0028289326 scopus 로고
    • Confirmation of association between the ∈4 allele of apolipoprotein E and Alzheimer's disease
    • Liddell M, Williams J, Bayer A, Kaiser F, Owen M. Confirmation of association between the ∈4 allele of apolipoprotein E and Alzheimer's disease. J Med Genet 1994;31:197-200.
    • (1994) J Med Genet , vol.31 , pp. 197-200
    • Liddell, M.1    Williams, J.2    Bayer, A.3    Kaiser, F.4    Owen, M.5
  • 8
    • 0028167193 scopus 로고
    • Confirmation of the ∈4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease
    • Brousseau T, Legrain S, Berr C, Gourlet V, Vidai O, Amouyel P. Confirmation of the ∈4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease. Neurology 1994;44:342-344.
    • (1994) Neurology , vol.44 , pp. 342-344
    • Brousseau, T.1    Legrain, S.2    Berr, C.3    Gourlet, V.4    Vidai, O.5    Amouyel, P.6
  • 9
    • 0029655833 scopus 로고    scopus 로고
    • Influence of apolipoprotein E genotype on the transmission of Alzheimer's disease in a community-based sample
    • Jarvik GP, Larson EB, Goddard K, Kukull WA, Schellenberg GD, Wijsman EM. Influence of apolipoprotein E genotype on the transmission of Alzheimer's disease in a community-based sample. Am J Hum Genet 1996;58:191-200.
    • (1996) Am J Hum Genet , vol.58 , pp. 191-200
    • Jarvik, G.P.1    Larson, E.B.2    Goddard, K.3    Kukull, W.A.4    Schellenberg, G.D.5    Wijsman, E.M.6
  • 10
    • 0028961402 scopus 로고
    • Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans
    • Hendrie HC, Hall KS, Hui S, et al. Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans. Ann Neurol 1995;37:118-120.
    • (1995) Ann Neurol , vol.37 , pp. 118-120
    • Hendrie, H.C.1    Hall, K.S.2    Hui, S.3
  • 11
    • 0027946816 scopus 로고
    • Predictive value of apolipoprotein E genotyping in Alzheimer's disease: Results of an autopsy series and an analysis of several combined studies
    • Nalbantoglu J, Gilfix BM, Bertrand P, et al. Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies. Ann Neurol 1994;36:889-895.
    • (1994) Ann Neurol , vol.36 , pp. 889-895
    • Nalbantoglu, J.1    Gilfix, B.M.2    Bertrand, P.3
  • 12
    • 0028167195 scopus 로고
    • ApoE ∈4 allelic association with Alzheimer's disease: Independent confirmation using denaturing gradient gel electrophoresis
    • Peacock ML, Fink JK. ApoE ∈4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis. Neurology 1994;44:339-341.
    • (1994) Neurology , vol.44 , pp. 339-341
    • Peacock, M.L.1    Fink, J.K.2
  • 13
    • 0029133072 scopus 로고
    • Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans
    • Hendrie HC, Osuntokun BO, Hall KS, et al. Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans. Am J Psychiatry 1995; 152:1485-1492.
    • (1995) Am J Psychiatry , vol.152 , pp. 1485-1492
    • Hendrie, H.C.1    Osuntokun, B.O.2    Hall, K.S.3
  • 14
    • 0025891114 scopus 로고
    • Regional differences in apolipoprotein E polymorphism in Finland
    • Lehtimaki T, Moilanen T, Nikkari T, et al. Regional differences in apolipoprotein E polymorphism in Finland. Ann Med 1991;23:61-66.
    • (1991) Ann Med , vol.23 , pp. 61-66
    • Lehtimaki, T.1    Moilanen, T.2    Nikkari, T.3
  • 15
    • 0029037609 scopus 로고
    • Lack of association of apolipoprotein E allele ∈4 with late-onset Alzheimer's disease among Finnish centenarians
    • Sobel E, Louhija J, Sulkava R, et al. Lack of association of apolipoprotein E allele ∈4 with late-onset Alzheimer's disease among Finnish centenarians. Neurology 1995;45:903-907.
    • (1995) Neurology , vol.45 , pp. 903-907
    • Sobel, E.1    Louhija, J.2    Sulkava, R.3
  • 16
    • 0028169648 scopus 로고
    • Reduced apolipoprotein ∈4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals
    • Rebeck GW, Perls TT, West HL, Sodhi P, Lipsitz LA, Hyman BT. Reduced apolipoprotein ∈4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals. Neurology 1994;44:1513-1516.
    • (1994) Neurology , vol.44 , pp. 1513-1516
    • Rebeck, G.W.1    Perls, T.T.2    West, H.L.3    Sodhi, P.4    Lipsitz, L.A.5    Hyman, B.T.6
  • 17
    • 0028305380 scopus 로고
    • Protective effect of apolipoprotein E type 2 allele for late-onset Alzheimer disease
    • Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late-onset Alzheimer disease. Nature Genet 1994;7:180-184.
    • (1994) Nature Genet , vol.7 , pp. 180-184
    • Corder, E.H.1    Saunders, A.M.2    Risch, N.J.3
  • 19
    • 18744430888 scopus 로고
    • Protective effect of apoE ∈2 in Alzheimer's disease
    • Benjamin R, Leake A, McArthur FK, et al. Protective effect of apoE ∈2 in Alzheimer's disease [letter]. Lancet 1994;344:473.
    • (1994) Lancet , vol.344 , pp. 473
    • Benjamin, R.1    Leake, A.2    McArthur, F.K.3
  • 20
    • 0028898784 scopus 로고
    • Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals
    • Petersen RC, Smith GE, Ivnik RJ, et al. Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals. JAMA 1995;273:1274-1278.
    • (1995) JAMA , vol.273 , pp. 1274-1278
    • Petersen, R.C.1    Smith, G.E.2    Ivnik, R.J.3
  • 21
    • 0029931412 scopus 로고    scopus 로고
    • A prospective study of the clinical utility of ApoE genotyping the prediction of outcome in patients with memory impairment
    • Tierney MC, Szalai JP, Snow WG, et al. A prospective study of the clinical utility of ApoE genotyping the prediction of outcome in patients with memory impairment. Neurology 1996; 46:149-154.
    • (1996) Neurology , vol.46 , pp. 149-154
    • Tierney, M.C.1    Szalai, J.P.2    Snow, W.G.3
  • 22
    • 0028988735 scopus 로고
    • Gene dose of the ∈4 allele of apolipoprotein E and disease progression in sporadic lateonset Alzheimer's disease
    • Frisoni GB, Govoni S, Geroldi C. Gene dose of the ∈4 allele of apolipoprotein E and disease progression in sporadic lateonset Alzheimer's disease. Ann Neurol 1995;37:596-604.
    • (1995) Ann Neurol , vol.37 , pp. 596-604
    • Frisoni, G.B.1    Govoni, S.2    Geroldi, C.3
  • 23
    • 0029665363 scopus 로고    scopus 로고
    • Apolipoprotein E ∈4 allele, cognitive decline, and deterioration of everyday performance in Alzheimer's disease
    • Kurz A, Egensperger R, Haupt M, et al. Apolipoprotein E ∈4 allele, cognitive decline, and deterioration of everyday performance in Alzheimer's disease. Neurology 1996;47:440-443.
    • (1996) Neurology , vol.47 , pp. 440-443
    • Kurz, A.1    Egensperger, R.2    Haupt, M.3
  • 24
    • 0029789379 scopus 로고    scopus 로고
    • Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease
    • Growdon JH, Locascio JJ, Corkin S, Gomez-Isla T, Hyman BT. Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease. Neurology 1996;47: 444-448.
    • (1996) Neurology , vol.47 , pp. 444-448
    • Growdon, J.H.1    Locascio, J.J.2    Corkin, S.3    Gomez-Isla, T.4    Hyman, B.T.5
  • 25
    • 0028325294 scopus 로고
    • Alzheimer's disease, apolipoprotein E4, and gender
    • Payami H, Montee KR, Kaye JA, et al. Alzheimer's disease, apolipoprotein E4, and gender. JAMA 1994;271:1316-1317.
    • (1994) JAMA , vol.271 , pp. 1316-1317
    • Payami, H.1    Montee, K.R.2    Kaye, J.A.3
  • 26
    • 0028831614 scopus 로고
    • The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease
    • Corder EH, Saunders AM, Strittmatter WJ, et al. The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease. JAMA 1995;273:373-374.
    • (1995) JAMA , vol.273 , pp. 373-374
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 27
    • 0028805682 scopus 로고
    • Apolipoprotein E genotype in patients with Alzheimer's disease: Implications for the risk of dementia among relatives
    • Farrer LA, Cupples LA, van Duijn CM, et al. Apolipoprotein E genotype in patients with Alzheimer's disease: implications for the risk of dementia among relatives. Ann Neurol 1995;38: 797-808.
    • (1995) Ann Neurol , vol.38 , pp. 797-808
    • Farrer, L.A.1    Cupples, L.A.2    Van Duijn, C.M.3
  • 28
    • 0029996705 scopus 로고    scopus 로고
    • Apolipoprotein E and cognitive change in the elderly population
    • Hyman BT, Gomez-Isla T, Briggs M, et al. Apolipoprotein E and cognitive change in the elderly population. Ann Neurol 1996;40:55-66.
    • (1996) Ann Neurol , vol.40 , pp. 55-66
    • Hyman, B.T.1    Gomez-Isla, T.2    Briggs, M.3
  • 29
    • 0028889485 scopus 로고
    • Statement on use of apolipoprotein E testing for Alzheimer's disease
    • Farrer LA, Brin MF, Elsas L, et al. Statement on use of apolipoprotein E testing for Alzheimer's disease. JAMA 1995; 274:1627-1629.
    • (1995) JAMA , vol.274 , pp. 1627-1629
    • Farrer, L.A.1    Brin, M.F.2    Elsas, L.3
  • 30
    • 0029944411 scopus 로고    scopus 로고
    • Apolipoprotein E genotyping in Alzheimer's disease
    • National Institute on Aging/Alzheimer's Association Working Group. Apolipoprotein E genotyping in Alzheimer's disease. Lancet 1996;347:1091-1095.
    • (1996) Lancet , vol.347 , pp. 1091-1095
  • 31
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 32
    • 0028997817 scopus 로고
    • Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease
    • Roses AD. Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease. Ann Neurol 1995;38:6-14.
    • (1995) Ann Neurol , vol.38 , pp. 6-14
    • Roses, A.D.1
  • 33
    • 15844393893 scopus 로고    scopus 로고
    • Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease
    • Saunders AM, Hulette C, Welsh-Bohmer KA, et al. Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease. Lancet 1996;348:90-93.
    • (1996) Lancet , vol.348 , pp. 90-93
    • Saunders, A.M.1    Hulette, C.2    Welsh-Bohmer, K.A.3
  • 34
    • 0024561665 scopus 로고
    • Genetic studies of human apolipoproteins. VI. Common polymorphism of apolipoprotein E in blacks
    • Kamboh MI, Sephernia B, Ferrell RE. Genetic studies of human apolipoproteins. VI. Common polymorphism of apolipoprotein E in blacks. Dis Markers 1989;7:49-55.
    • (1989) Dis Markers , vol.7 , pp. 49-55
    • Kamboh, M.I.1    Sephernia, B.2    Ferrell, R.E.3
  • 35
    • 0028033804 scopus 로고
    • Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: Implications for Alzheimer's disease
    • Huang DY, Goedert M, Jakes R, et al. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neurosci Lett 1994;182:55-58.
    • (1994) Neurosci Lett , vol.182 , pp. 55-58
    • Huang, D.Y.1    Goedert, M.2    Jakes, R.3
  • 36
    • 12044254746 scopus 로고
    • Binding of human apolipoprotein E to synthetic amyloid beta-peptide: Isoform-specific effects and implications for late-onset Alzheimer's disease
    • Strittmatter WJ, Weisgraber KH, Huang DY, et al. Binding of human apolipoprotein E to synthetic amyloid beta-peptide: isoform-specific effects and implications for late-onset Alzheimer's disease. Proc Natl Acad Sci USA 1993;90:8098-8102.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8098-8102
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Huang, D.Y.3
  • 37
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides
    • Miyata M, Smith JD. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides. Nature Genet 1996;14:55-61.
    • (1996) Nature Genet , vol.14 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 38
    • 0028950856 scopus 로고
    • Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer's disease
    • Small GW, Mazziotta JC, Collins MT, et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer's disease. JAMA 1995;273:942-947.
    • (1995) JAMA , vol.273 , pp. 942-947
    • Small, G.W.1    Mazziotta, J.C.2    Collins, M.T.3
  • 39
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies P, Maloney AL. Selective loss of central cholinergic neurons in Alzheimer's disease [letter]. Lancet 1976;2:1403.
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.L.2
  • 40
    • 0019410162 scopus 로고
    • Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
    • Whitehouse PJ, Price DL, Clark AW, Coyle JT, DeLong MR. Alzheimer's disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol 1981;10:122-126.
    • (1981) Ann Neurol , vol.10 , pp. 122-126
    • Whitehouse, P.J.1    Price, D.L.2    Clark, A.W.3    Coyle, J.T.4    DeLong, M.R.5
  • 41
    • 0026792979 scopus 로고
    • A controlled trial of tacrine in Alzheimer's disease
    • Farlow M, Gracon SI, Hershey LA, et al. A controlled trial of tacrine in Alzheimer's disease. JAMA 1992;268:2523-2529.
    • (1992) JAMA , vol.268 , pp. 2523-2529
    • Farlow, M.1    Gracon, S.I.2    Hershey, L.A.3
  • 42
    • 0028270519 scopus 로고
    • A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
    • Knapp MJ, Knopman DS, Solomon PR, et al. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA 1994;271:985-991.
    • (1994) JAMA , vol.271 , pp. 985-991
    • Knapp, M.J.1    Knopman, D.S.2    Solomon, P.R.3
  • 43
    • 0008941101 scopus 로고
    • Jul 7. Rockville, MD: Department of Health and Human Services, Public Health Service, Food and Drug Administration, 1989
    • Report of the Peripheral and Central Nervous System Drugs Advisory Committee Meeting, 1989, Jul 7. Rockville, MD: Department of Health and Human Services, Public Health Service, Food and Drug Administration, 1989;227.
    • (1989) Report of the Peripheral and Central Nervous System Drugs Advisory Committee Meeting , pp. 227
  • 44
    • 0029087595 scopus 로고
    • Predicting response to cholinesterase inhibitors in Alzheimer's disease: Possible approaches
    • Schneider LS, Farlow MR. Predicting response to cholinesterase inhibitors in Alzheimer's disease: possible approaches. CNS Drugs 1995;4:144-124.
    • (1995) CNS Drugs , vol.4 , pp. 144-1124
    • Schneider, L.S.1    Farlow, M.R.2
  • 45
    • 0007691164 scopus 로고
    • Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease
    • Poirier J, Delisle M-C, Quirion R, et al. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease. Proc Natl Acad Sci USA 1995;92: 12260-12264.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12260-12264
    • Poirier, J.1    Delisle, M.-C.2    Quirion, R.3
  • 46
    • 0343207754 scopus 로고    scopus 로고
    • Apolipoprotein E genotype predicts response to tacrine in Alzheimer's disease
    • Farlow MR, Lahiri D, Hui S, Davignon J. Apolipoprotein E genotype predicts response to tacrine in Alzheimer's disease [abstract]. Neurology 1996;46(suppl 2):A217.
    • (1996) Neurology , vol.46 , Issue.2 SUPPL.
    • Farlow, M.R.1    Lahiri, D.2    Hui, S.3    Davignon, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.