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Volumn 347, Issue 9008, 1996, Pages 1091-1095

Apolipoprotein E genotyping in Alzheimer's disease: National Institute on Aging/Alzheimer's Association Working Group

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4;

EID: 0029944411     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)90284-6     Document Type: Conference Paper
Times cited : (257)

References (77)
  • 1
    • 0027407565 scopus 로고
    • Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
    • Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci 1993; 90: 1977-81.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3
  • 2
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993; 261: 921-31.
    • (1993) Science , vol.261 , pp. 921-931
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 3
    • 0027339923 scopus 로고
    • The apolipoprotein ∈4 allele in patients with Alzheimer's disease
    • Mayeux R, Stern Y, Ottman R, et al. The apolipoprotein ∈4 allele in patients with Alzheimer's disease. Ann Neurol 1993; 34: 752-54.
    • (1993) Ann Neurol , vol.34 , pp. 752-754
    • Mayeux, R.1    Stern, Y.2    Ottman, R.3
  • 4
    • 0027327267 scopus 로고
    • Association of apolipoprotein E allele ∈4 with late-onset familial and sporadic Alzheimer's disease
    • Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele ∈4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993; 43: 1467-72.
    • (1993) Neurology , vol.43 , pp. 1467-1472
    • Saunders, A.M.1    Strittmatter, W.J.2    Schmechel, D.3
  • 5
    • 0027282035 scopus 로고
    • Apolipoprotein E polymorphism and Alzheimer's disease
    • Poirier J, Davignon J, Bouthillier D, et al. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 1993; 342: 697-99.
    • (1993) Lancet , vol.342 , pp. 697-699
    • Poirier, J.1    Davignon, J.2    Bouthillier, D.3
  • 6
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck GW, Reiter JS, Strickland DK, et al. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 1993; 11: 575-80.
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3
  • 7
    • 0027946816 scopus 로고
    • Predictive value of apolipoprotein E genotyping in Alzheimer's disease: Results of an autopsy series and an analysis of several combined studies
    • Nalbantoglu J, Gilfix BM, Bertrand P, et al. Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies. Ann Neurol 1994; 36: 889-95.
    • (1994) Ann Neurol , vol.36 , pp. 889-895
    • Nalbantoglu, J.1    Gilfix, B.M.2    Bertrand, P.3
  • 8
    • 0028301820 scopus 로고
    • Apolipoprotein E: Risk factor for Alzheimer's disease
    • Tsai M-S, Tangalos EG, Petersen RC, et al. Apolipoprotein E: risk factor for Alzheimer's disease. Am J Hum Genet 1994; 54: 643-49.
    • (1994) Am J Hum Genet , vol.54 , pp. 643-649
    • Tsai, M.-S.1    Tangalos, E.G.2    Petersen, R.C.3
  • 9
    • 23444438235 scopus 로고
    • The apolipoprotein E/C/CII gene cluster and late-onset Alzheimer disease
    • Yu C-E, Payami H, Olson JM, et al. The apolipoprotein E/C/CII gene cluster and late-onset Alzheimer disease. Am J Hum Genet 1994; 54: 631-42.
    • (1994) Am J Hum Genet , vol.54 , pp. 631-642
    • Yu, C.-E.1    Payami, H.2    Olson, J.M.3
  • 10
    • 0028058838 scopus 로고
    • Association of the apolipoprotein E ∈4 allele with clinical subtypes of autopsy-confirmed Alzheimer's disease
    • Zubenko GS, Stiffler S, Stabler S, et al. Association of the apolipoprotein E ∈4 allele with clinical subtypes of autopsy-confirmed Alzheimer's disease. Am J Med Genet 1994; 54: 199-205.
    • (1994) Am J Med Genet , vol.54 , pp. 199-205
    • Zubenko, G.S.1    Stiffler, S.2    Stabler, S.3
  • 11
    • 0028340614 scopus 로고
    • Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus
    • Houlden H, Crook R, Hardy J, et al. Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus. Neurosci Lett 1994; 174: 222-24.
    • (1994) Neurosci Lett , vol.174 , pp. 222-224
    • Houlden, H.1    Crook, R.2    Hardy, J.3
  • 12
    • 0028167195 scopus 로고
    • ApoE ∈4 allelic association with Alzheimer's disease: Independent confirmation using denaturing gradient gel electrophoresis
    • Peacock ML, Fink JK. ApoE ∈4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis. Neurology 1994; 44: 339-41.
    • (1994) Neurology , vol.44 , pp. 339-341
    • Peacock, M.L.1    Fink, J.K.2
  • 13
    • 0029664414 scopus 로고    scopus 로고
    • Apolipoprotein E ∈4 association with dementia in a population based study: The Framingham Study
    • Myers RH, Schaefer EJ, Wilson PWF, et al. Apolipoprotein E ∈4 association with dementia in a population based study: the Framingham Study. Neurology 1996; 46: 673-77.
    • (1996) Neurology , vol.46 , pp. 673-677
    • Myers, R.H.1    Schaefer, E.J.2    Wilson, P.W.F.3
  • 14
    • 0027921557 scopus 로고
    • Apolipoprotein E-∈4 allele and Alzheimer's disease
    • Anwar N, Lovestone S, Cheetham ME, et al. Apolipoprotein E-∈4 allele and Alzheimer's disease. Lancet 1993; 342: 1308-09.
    • (1993) Lancet , vol.342 , pp. 1308-1309
    • Anwar, N.1    Lovestone, S.2    Cheetham, M.E.3
  • 15
    • 0027921538 scopus 로고
    • Apolipoprotein E-∈4 allele and Alzheimer's disease
    • Czech C, Monning U, Tienari PJ, et al. Apolipoprotein E-∈4 allele and Alzheimer's disease. Lancet 1993; 342: 1309-10.
    • (1993) Lancet , vol.342 , pp. 1309-1310
    • Czech, C.1    Monning, U.2    Tienari, P.J.3
  • 16
    • 0027921547 scopus 로고
    • Apolipoprotein E-∈4 allele and Alzheimer's disease
    • Lucotte G, David F, Visvikis S, et al. Apolipoprotein E-∈4 allele and Alzheimer's disease. Lancet 1993; 342: 1308-09.
    • (1993) Lancet , vol.342 , pp. 1308-1309
    • Lucotte, G.1    David, F.2    Visvikis, S.3
  • 17
    • 0028167193 scopus 로고
    • Confirmation of the ∈4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease
    • Brousseau T, Legrain S, Berr C, et al. Confirmation of the ∈4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease. Neurology 1994; 44: 342-44.
    • (1994) Neurology , vol.44 , pp. 342-344
    • Brousseau, T.1    Legrain, S.2    Berr, C.3
  • 18
    • 0028289326 scopus 로고
    • Confirmation of association between the ∈4 allele of apolipoprotein E and Alzheimer's disease
    • Liddell M, Williams J, Bayer A, et al. Confirmation of association between the ∈4 allele of apolipoprotein E and Alzheimer's disease. J Med Genet 1994; 31: 197-200.
    • (1994) J Med Genet , vol.31 , pp. 197-200
    • Liddell, M.1    Williams, J.2    Bayer, A.3
  • 19
    • 0028141602 scopus 로고
    • Association of apolipoprotein E allele ∈4 with late-onset sporadic Alzheimer's disease
    • Lucotte G, Visvikis S, Leininger-Muler B, et al. Association of apolipoprotein E allele ∈4 with late-onset sporadic Alzheimer's disease. Am J Med Genet 1994; 54: 286-88.
    • (1994) Am J Med Genet , vol.54 , pp. 286-288
    • Lucotte, G.1    Visvikis, S.2    Leininger-Muler, B.3
  • 20
    • 0028178047 scopus 로고
    • Apolipoprotein E, ∈4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13.2 chromosomal region
    • Chartier-Harlin M-C, Parfitt M, Legrain S, et al. Apolipoprotein E, ∈4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region. Hum Mol Genet 1994; 3: 569-74.
    • (1994) Hum Mol Genet , vol.3 , pp. 569-574
    • Chartier-Harlin, M.-C.1    Parfitt, M.2    Legrain, S.3
  • 21
    • 0028841027 scopus 로고
    • Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein
    • Polvikoski T, Sulkava R, Haltia M, et al. Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein. N Engl J Med 1995; 333: 1242-47.
    • (1995) N Engl J Med , vol.333 , pp. 1242-1247
    • Polvikoski, T.1    Sulkava, R.2    Haltia, M.3
  • 22
    • 0028278679 scopus 로고
    • Apolipoprotein E4: Phenotype in patients with Alzheimer's disease
    • Mahieux F, Couderc R, Moulignier A, et al. Apolipoprotein E4: phenotype in patients with Alzheimer's disease. Ann Neurol 1994; 35: 506.
    • (1994) Ann Neurol , vol.35 , pp. 506
    • Mahieux, F.1    Couderc, R.2    Moulignier, A.3
  • 23
    • 0028137052 scopus 로고
    • ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease
    • Sorbi S, Nacmias B, Forleo P, et al. ApoE allele frequencies in Italian sporadic and familial Alzheimer's disease. Neurosci Lett 1994; 177: 100-02.
    • (1994) Neurosci Lett , vol.177 , pp. 100-102
    • Sorbi, S.1    Nacmias, B.2    Forleo, P.3
  • 24
    • 0028167740 scopus 로고
    • Association of apolipoprotein E phenotypes with late onset Alzheimer's diseases: Population based study
    • Kuusisto J, Koivisto K, Kervinen K, et al. Association of apolipoprotein E phenotypes with late onset Alzheimer's diseases: population based study. BMJ 1994; 309: 636-38.
    • (1994) BMJ , vol.309 , pp. 636-638
    • Kuusisto, J.1    Koivisto, K.2    Kervinen, K.3
  • 25
    • 0028981271 scopus 로고
    • Apolipoprotein ∈4 allele and disease progression in patients with late-onset Alzheimer's disease
    • Basun H, Grut M, Winblad B, et al. Apolipoprotein ∈4 allele and disease progression in patients with late-onset Alzheimer's disease. Neurosci Lett 1995; 183: 32-34.
    • (1995) Neurosci Lett , vol.183 , pp. 32-34
    • Basun, H.1    Grut, M.2    Winblad, B.3
  • 26
    • 0027203749 scopus 로고
    • Apolipoprotein E genotype and Alzheimer's disease
    • Noguchi S, Murakami K, Yamada N. Apolipoprotein E genotype and Alzheimer's disease. Lancet 1993; 342: 737.
    • (1993) Lancet , vol.342 , pp. 737
    • Noguchi, S.1    Murakami, K.2    Yamada, N.3
  • 27
    • 0027146623 scopus 로고
    • A high frequency of apolipoprotein E4 isoprotein in Japanese patients with late-onset nonfamilial Alzheimer's disease
    • Ueki A, Kawano M, Namba Y. A high frequency of apolipoprotein E4 isoprotein in Japanese patients with late-onset nonfamilial Alzheimer's disease. Neurosci Lett 1993; 163: 166-68.
    • (1993) Neurosci Lett , vol.163 , pp. 166-168
    • Ueki, A.1    Kawano, M.2    Namba, Y.3
  • 28
    • 0028124454 scopus 로고
    • Dose-dependent association of apolipoprotein E allele ∈4 with late-onset, sporadic Alzheimer's disease
    • Yoshizawa T, Yamakawa-Kobayashi K, Komatsuzaki Y, et al. Dose-dependent association of apolipoprotein E allele ∈4 with late-onset, sporadic Alzheimer's disease. Ann Neurol 1994; 36: 656-59.
    • (1994) Ann Neurol , vol.36 , pp. 656-659
    • Yoshizawa, T.1    Yamakawa-Kobayashi, K.2    Komatsuzaki, Y.3
  • 29
    • 0028172603 scopus 로고
    • Apolipoprotein E ∈4 allele distribution in alcoholic dementia and in Alzheimer's disease in Japan
    • Muramatsu T, Higuchi S, Arai H, et al. Apolipoprotein E ∈4 allele distribution in alcoholic dementia and in Alzheimer's disease in Japan. Ann Neurol 1994; 36: 797-99.
    • (1994) Ann Neurol , vol.36 , pp. 797-799
    • Muramatsu, T.1    Higuchi, S.2    Arai, H.3
  • 30
    • 0029031916 scopus 로고
    • Apolipoprotein E genotyping in the diagnosis of Alzheimer's disease: A cautionary view
    • Bird TD. Apolipoprotein E genotyping in the diagnosis of Alzheimer's disease: a cautionary view. Ann Neurol 1995; 38: 2-4.
    • (1995) Ann Neurol , vol.38 , pp. 2-4
    • Bird, T.D.1
  • 31
    • 0028305380 scopus 로고
    • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
    • Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genet 1994; 7: 180-84.
    • (1994) Nature Genet , vol.7 , pp. 180-184
    • Corder, E.H.1    Saunders, A.M.2    Risch, N.J.3
  • 32
    • 0027337858 scopus 로고
    • Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases
    • Saunders AM, Schmader K, Breitner JCS, et al. Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 1993; 342: 710-11.
    • (1993) Lancet , vol.342 , pp. 710-711
    • Saunders, A.M.1    Schmader, K.2    Breitner, J.C.S.3
  • 33
    • 0028817272 scopus 로고
    • Apolipoprotein E in Creutzfeldt-Jakob disease
    • Nakagawa Y, Kitamoto T, Furukawa H, et al. Apolipoprotein E in Creutzfeldt-Jakob disease. Lancet 1995; 345: 68.
    • (1995) Lancet , vol.345 , pp. 68
    • Nakagawa, Y.1    Kitamoto, T.2    Furukawa, H.3
  • 34
    • 0028113971 scopus 로고
    • The apoliprotein E allele epsilon 4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease
    • Galasko D, Saitoh T, Xia Y, et al. The apoliprotein E allele epsilon 4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease. Neurology 1994; 44: 1950-51.
    • (1994) Neurology , vol.44 , pp. 1950-1951
    • Galasko, D.1    Saitoh, T.2    Xia, Y.3
  • 35
    • 0029113023 scopus 로고
    • ApoE genotypes in Australia: Roles in early and late onset Alzheimer's disease and Down's syndrome
    • Martins RN, Clarnette R, Fisher C, et al. ApoE genotypes in Australia: roles in early and late onset Alzheimer's disease and Down's syndrome. Neuroreport 1995; 6: 1513-16.
    • (1995) Neuroreport , vol.6 , pp. 1513-1516
    • Martins, R.N.1    Clarnette, R.2    Fisher, C.3
  • 36
    • 0028091522 scopus 로고
    • Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types: Significance for etiological theories of Alzheimer's disease
    • Harrington CR, Louwagie J, Rossau R, et al. Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types: significance for etiological theories of Alzheimer's disease. Am J Pathol 1994; 145: 1472-84.
    • (1994) Am J Pathol , vol.145 , pp. 1472-1484
    • Harrington, C.R.1    Louwagie, J.2    Rossau, R.3
  • 37
    • 0028972112 scopus 로고
    • Apolipoprotein E ∈4 allele frequency is not increased in progressive supranuclear palsy
    • Tabaton M, Rolleri M, Masturzo P, et al. Apolipoprotein E ∈4 allele frequency is not increased in progressive supranuclear palsy. Neurology 1995; 45: 1764-65.
    • (1995) Neurology , vol.45 , pp. 1764-1765
    • Tabaton, M.1    Rolleri, M.2    Masturzo, P.3
  • 38
    • 0028798254 scopus 로고
    • Apolipoprotein E genotypes in Parkinson's disease with and without dementia
    • Koller WC, Glatt SL, Hubble JP, et al. Apolipoprotein E genotypes in Parkinson's disease with and without dementia. Ann Neurol 1995; 37: 242-45.
    • (1995) Ann Neurol , vol.37 , pp. 242-245
    • Koller, W.C.1    Glatt, S.L.2    Hubble, J.P.3
  • 40
    • 0029754637 scopus 로고    scopus 로고
    • Alzheimer amyloid-β peptide forms denaturant-resistant complex with type ∈3 but not type ∈4 isoform of native apolipoprotein E
    • Zhou Z, Smith JD, Greengard P, et al. Alzheimer amyloid-β peptide forms denaturant-resistant complex with type ∈3 but not type ∈4 isoform of native apolipoprotein E. Mol Med 1996; 2: 175-80.
    • (1996) Mol Med , vol.2 , pp. 175-180
    • Zhou, Z.1    Smith, J.D.2    Greengard, P.3
  • 41
    • 0028035306 scopus 로고
    • Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: Implications for Alzheimer disease
    • Strittmatter WH, Saunders AM, Goedert M, et al. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proc Natl Acad Sci 1994; 91: 11183-86.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 11183-11186
    • Strittmatter, W.H.1    Saunders, A.M.2    Goedert, M.3
  • 42
    • 0028172930 scopus 로고
    • Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease
    • Poirer J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci 1994; 17: 525-30.
    • (1994) Trends Neurosci , vol.17 , pp. 525-530
    • Poirer, J.1
  • 43
    • 0007691164 scopus 로고
    • Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease
    • Poirier J, Delisle M-C, Quinion R, et al. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease. Proc Natl Acad Sci 1995; 92: 12260-64.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 12260-12264
    • Poirier, J.1    Delisle, M.-C.2    Quinion, R.3
  • 44
    • 0028816355 scopus 로고
    • Apolipoprotein E and Alzheimer's disease: Ethnic variation in genotypic risks
    • Maestre G, Ottman R, Stern Y, et al. Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks. Ann Neurol 1995; 37: 254-59.
    • (1995) Ann Neurol , vol.37 , pp. 254-259
    • Maestre, G.1    Ottman, R.2    Stern, Y.3
  • 45
    • 0028169648 scopus 로고
    • Reduced apolipoprotein ∈4 allele frequency in the oldest old Alzheimer patients and cognitively normal individuals
    • Rebeck GW, Perls TT, West HL, et al. Reduced apolipoprotein ∈4 allele frequency in the oldest old Alzheimer patients and cognitively normal individuals. Neurology 1994; 44: 1513-16.
    • (1994) Neurology , vol.44 , pp. 1513-1516
    • Rebeck, G.W.1    Perls, T.T.2    West, H.L.3
  • 46
    • 0023853488 scopus 로고
    • Familial aggregation in Alzheimer's disease: Comparison of risk among relatives of early- and late-onset cases, and among male and female relatives in successive generations
    • Breitner JCS, Silverman JM, Mohs RC, et al. Familial aggregation in Alzheimer's disease: comparison of risk among relatives of early- and late-onset cases, and among male and female relatives in successive generations. Neurology 1988; 38: 207-12.
    • (1988) Neurology , vol.38 , pp. 207-212
    • Breitner, J.C.S.1    Silverman, J.M.2    Mohs, R.C.3
  • 47
    • 0028805682 scopus 로고
    • Apolipoprotein E genotype in patients with Alzheimer's disease: Implications for the risk of dementia among relatives
    • Farrer LA, Cupples LA, Van Duijn CM, et al. Apolipoprotein E genotype in patients with Alzheimer's disease: implications for the risk of dementia among relatives. Ann Neurol 1995; 38: 797-808.
    • (1995) Ann Neurol , vol.38 , pp. 797-808
    • Farrer, L.A.1    Cupples, L.A.2    Van Duijn, C.M.3
  • 48
    • 0028222352 scopus 로고
    • Patterns of risk in first-degree relatives of patients with Alzheimer's disease
    • Silverman JM, Li G, Zaccario ML, et al. Patterns of risk in first-degree relatives of patients with Alzheimer's disease. Arch Gen Psychiatry 1994; 51: 577-86.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 577-586
    • Silverman, J.M.1    Li, G.2    Zaccario, M.L.3
  • 49
    • 0027375845 scopus 로고
    • Assessing the risk of Alzheimer's disease in first-degree relatives of Alzheimer's disease cases
    • Korten AE, Jorm AF, Henderson AS. Assessing the risk of Alzheimer's disease in first-degree relatives of Alzheimer's disease cases. Psychol Med 1993; 23: 915-23.
    • (1993) Psychol Med , vol.23 , pp. 915-923
    • Korten, A.E.1    Jorm, A.F.2    Henderson, A.S.3
  • 50
    • 0027919960 scopus 로고
    • Apolipoprotein E genotype and Alzheimer's disease
    • Payami H, Kaye J, Heston LL, et al. Apolipoprotein E genotype and Alzheimer's disease. Lancet 1993; 342: 738.
    • (1993) Lancet , vol.342 , pp. 738
    • Payami, H.1    Kaye, J.2    Heston, L.L.3
  • 51
    • 0028906609 scopus 로고
    • Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's disease but is not causative
    • Bennett C, Crawford F, Osborne A, et al. Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's disease but is not causative. Am J Med Genet 1995; 60: 1-6.
    • (1995) Am J Med Genet , vol.60 , pp. 1-6
    • Bennett, C.1    Crawford, F.2    Osborne, A.3
  • 52
    • 0028278060 scopus 로고
    • Protection against Alzheimer's disease with apoE ∈2
    • Talbot C, Lendon C, Craddock N, et al. Protection against Alzheimer's disease with apoE ∈2. Lancet 1994; 343: 1432-33.
    • (1994) Lancet , vol.343 , pp. 1432-1433
    • Talbot, C.1    Lendon, C.2    Craddock, N.3
  • 53
    • 18744430888 scopus 로고
    • Protective effect of apo E ∈2 in Alzheimer's disease
    • Smith AD, Leake A, McArthur FK, et al. Protective effect of apo E ∈2 in Alzheimer's disease. Lancet 1994; 344: 473-74.
    • (1994) Lancet , vol.344 , pp. 473-474
    • Smith, A.D.1    Leake, A.2    McArthur, F.K.3
  • 54
    • 18744430888 scopus 로고
    • Protective effect of apo E ∈2 in Alzheimer's disease
    • Benjamin R, Johnston C, Sim E, et al. Protective effect of apo E ∈2 in Alzheimer's disease. Lancet 1994; 344: 473.
    • (1994) Lancet , vol.344 , pp. 473
    • Benjamin, R.1    Johnston, C.2    Sim, E.3
  • 55
    • 0028282762 scopus 로고
    • Frequency of the apolipoprotein e ∈2 allele is diminished in sporadic Alzheimer disease
    • West HL, Rebeck GW, Hyman BT. Frequency of the apolipoprotein E ∈2 allele is diminished in sporadic Alzheimer disease. Neurosci Lett 1994; 175: 46-48.
    • (1994) Neurosci Lett , vol.175 , pp. 46-48
    • West, H.L.1    Rebeck, G.W.2    Hyman, B.T.3
  • 56
    • 0028843391 scopus 로고
    • Apolipoprotein E4 allele and Alzheimer disease: Examination of allelic association and effect on age at onset in both early- and late-onset cases
    • Locke PA, Conneally PM, Tanzi RE, et al. Apolipoprotein E4 allele and Alzheimer disease: examination of allelic association and effect on age at onset in both early- and late-onset cases. Genet Epidemiol 1995; 12: 83-92.
    • (1995) Genet Epidemiol , vol.12 , pp. 83-92
    • Locke, P.A.1    Conneally, P.M.2    Tanzi, R.E.3
  • 57
    • 0028990941 scopus 로고
    • APOE4 associated Alzheimer's disease risk is modified by α 1 antichymotrypsin polymorphism
    • Kamboh MI, Sanghera DK, Ferrell RE, et al. APOE4 associated Alzheimer's disease risk is modified by α 1 antichymotrypsin polymorphism. Nature Genet 1995; 10: 486-88.
    • (1995) Nature Genet , vol.10 , pp. 486-488
    • Kamboh, M.I.1    Sanghera, D.K.2    Ferrell, R.E.3
  • 58
    • 0028325294 scopus 로고
    • Alzheimer's disease, apolipoprotein E and gender
    • Payami H, Monte KR, Kaye JA, et al. Alzheimer's disease, apolipoprotein E and gender. JAMA 1994; 271: 1316-17.
    • (1994) JAMA , vol.271 , pp. 1316-1317
    • Payami, H.1    Monte, K.R.2    Kaye, J.A.3
  • 59
    • 0028316441 scopus 로고
    • ApoE genotype and Down's syndrome
    • Hardy J, Crook R, Perry R, et al. ApoE genotype and Down's syndrome. Lancet 1994; 343: 979-80.
    • (1994) Lancet , vol.343 , pp. 979-980
    • Hardy, J.1    Crook, R.2    Perry, R.3
  • 60
    • 0029018224 scopus 로고
    • Synergistic effects of traumatic head injury of apolipoprotein-epsilon 4 in patients with Alzheimer's disease
    • Mayeux R, Ottman R, Maestre G, et al. Synergistic effects of traumatic head injury of apolipoprotein-epsilon 4 in patients with Alzheimer's disease. Neurology 1995; 45: 555-57.
    • (1995) Neurology , vol.45 , pp. 555-557
    • Mayeux, R.1    Ottman, R.2    Maestre, G.3
  • 61
    • 0028670363 scopus 로고
    • Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia
    • Royston MC, Mann D, Pickering-Brown S, et al. Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia. Neuroreport 1994; 5: 2583-85.
    • (1994) Neuroreport , vol.5 , pp. 2583-2585
    • Royston, M.C.1    Mann, D.2    Pickering-Brown, S.3
  • 62
    • 0028952332 scopus 로고
    • The influence of apolipoprotein E isotypes on Alzheimer's disease pathology in 40 cases of Down's syndrome
    • Wisniewski T, Morelli L, Wegiel J, et al. The influence of apolipoprotein E isotypes on Alzheimer's disease pathology in 40 cases of Down's syndrome. Ann Neurol 1995; 37: 136-38.
    • (1995) Ann Neurol , vol.37 , pp. 136-138
    • Wisniewski, T.1    Morelli, L.2    Wegiel, J.3
  • 64
    • 0028889485 scopus 로고
    • Statement on use of apolipoprotein E testing for Alzheimer disease
    • Farrer LA, Brin MF, Elsas L, et al. Statement on use of apolipoprotein E testing for Alzheimer disease. JAMA 1995; 274: 1627-29.
    • (1995) JAMA , vol.274 , pp. 1627-1629
    • Farrer, L.A.1    Brin, M.F.2    Elsas, L.3
  • 65
    • 0028997817 scopus 로고
    • Apolipopotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease
    • Roses AD. Apolipopotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease. Ann Neurol 1995; 38: 6-14.
    • (1995) Ann Neurol , vol.38 , pp. 6-14
    • Roses, A.D.1
  • 66
    • 0029565149 scopus 로고
    • Consensus statement on predictive testing for Alzheimer disease
    • Brodaty H. Consensus statement on predictive testing for Alzheimer disease. Alzheimer Dis Assoc Disord 1995; 9: 182-87.
    • (1995) Alzheimer Dis Assoc Disord , vol.9 , pp. 182-187
    • Brodaty, H.1
  • 67
    • 0028973776 scopus 로고
    • Apolipoprotein E ∈4 allele and the lifetime risk of Alzheimer's disease: What physicians know, and what they should know
    • Seshadri S, Drachman D, Lippa C. Apolipoprotein E ∈4 allele and the lifetime risk of Alzheimer's disease: what physicians know, and what they should know. Arch Neurol 1995; 52: 1074-79.
    • (1995) Arch Neurol , vol.52 , pp. 1074-1079
    • Seshadri, S.1    Drachman, D.2    Lippa, C.3
  • 68
    • 0027482439 scopus 로고
    • Privacy rules for DNA databanks: Protecting coded 'future diaries'
    • Annas GJ. Privacy rules for DNA databanks: protecting coded 'future diaries'. JAMA 1993; 270: 2346-50.
    • (1993) JAMA , vol.270 , pp. 2346-2350
    • Annas, G.J.1
  • 70
    • 0028941978 scopus 로고
    • Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients
    • Kosunen O, Talasniemi S, Lehtovirta M, et al. Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients. Stroke 1995; 26: 743-48.
    • (1995) Stroke , vol.26 , pp. 743-748
    • Kosunen, O.1    Talasniemi, S.2    Lehtovirta, M.3
  • 71
    • 0028832051 scopus 로고
    • Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men
    • Stengard JH, Zerba KE, Pekkanen J, et al. Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men. Circulation 1995; 91: 265-69.
    • (1995) Circulation , vol.91 , pp. 265-269
    • Stengard, J.H.1    Zerba, K.E.2    Pekkanen, J.3
  • 72
    • 0029118904 scopus 로고
    • Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology 1995; 45: 1323-28.
    • (1995) Neurology , vol.45 , pp. 1323-1328
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 73
    • 0029151776 scopus 로고
    • Apolipoprotein e and Alzheimer's disease: The implications of progress in molecular medicine
    • Mayeux R, Schupf N. Apolipoprotein E and Alzheimer's disease: the implications of progress in molecular medicine. Am J Public Health 1995; 85: 1280-84.
    • (1995) Am J Public Health , vol.85 , pp. 1280-1284
    • Mayeux, R.1    Schupf, N.2
  • 74
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
    • Goate A, Chartier-Harlin M-C, Mullan M, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991; 349: 704-06.
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.-C.2    Mullan, M.3
  • 75
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
    • Sherrington R, Rogaev EI, Liang Y, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 1995; 375: 754-60.
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1    Rogaev, E.I.2    Liang, Y.3
  • 76
    • 0029150716 scopus 로고
    • A familial Alzheimer's disease locus on chromosome I
    • Levy-Lahad E, Wijsman EM, Nemens E, et al. A familial Alzheimer's disease locus on chromosome I. Science 1995; 269: 970-73.
    • (1995) Science , vol.269 , pp. 970-973
    • Levy-Lahad, E.1    Wijsman, E.M.2    Nemens, E.3
  • 77
    • 0028950856 scopus 로고
    • Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer's disease
    • Small GW, Mazziota JC, Collins MT, et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer's disease. JAMA 1995; 273: 942-46.
    • (1995) JAMA , vol.273 , pp. 942-946
    • Small, G.W.1    Mazziota, J.C.2    Collins, M.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.