Potential role of tachykinins in inflammatory diseases

Journal of Allergy and Clinical Immunology

Volumn 99, Issue 5, 1997, Pages 579-582

  Canning, Brendan J ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ A; NEUROKININ B; NEUROPEPTIDE; SUBSTANCE P; TACHYKININ RECEPTOR;

DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; INFLAMMATION; NERVE CELL PLASTICITY; NEUROMODULATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECEPTOR BLOCKING; REVIEW;

EID: 0030952040     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(97)70015-0     Document Type: Article

References (30)

1. Brace AN. Vasodilator axon-reflexes. Q J Exp Physiol 1913;6:339-54.
2. Lewis T. The nocifensor system of nerves and its reactions. Br Med J 1937;1:431-5.
3. Lewis T. The nocifensor system of nerves and its reactions. Br Med J 1937;1:491-7.
4. Jansco N, Jansco-Gabor A, Szolcsanyi J. Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin. Br J Pharmacol Chemother 1967;31:138-51.
5. Lundberg JM, Saria A. Capsaicin-induced desensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants. Nature 1983;302:251-3.
6. Otsuka M, Yoshioka K. Neurotransmitter functions of mammalian tachykinins. Physiol Rev 1993;73:229-308.
7. Lotti T, Hautmann G, Panconesi E. Neuropeptides in skin. J Am Acad Dermatol 1995;33:482-96.
8. Maggi CA, Meli A. The sensory-efferent function of capsaicin-sensitive sensory neurons. Gen Pharmacol 1988;19:1-43.
9. Pain: mechanisms and management. Br Med J 1991;47:523-675.
10. Peptides and their antagonists in tissue injury. Can J Physiol Pharmacol 1995;73:854-944.
11. Undem BJ, Myers AC. Neural regulation of the immune response. In: Holgate ST, Busse WW, editors. Asthma and rhinitis. 2nd ed. Boston: Blackwell Scientific Publications, 1997. In press.
12. Barnes PJ, Baraniuk JN, Belvisi MG. Neuropeptides in the respiratory tract. Am Rev Respir Dis 1991;144:1391-9.
13. Urban L, Thompson SWN, Dray A. Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci 1994;17:432-8.
14. DeKoninck Y, Ribeiro-Da-Silva A, Henry JL, Cuello C. Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contacts. Proc Nat Acad Sci USA 1992;89:5073-7.
15. Bertrand C, Geppetti P. Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease. Trends Pharmacol Sci 1996:17:255-9.
16. Braunstein G, Fajac I, Lacronique J, Frossard N. Clinical and inflammatory responses to exogenous tachykinins in allergic rhinitis. Am Rev Respir Dis 1991;144:630-5.
17. 1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea. Am J Physiol 1995;268:L263-L269.
18. Philip G, Sanico AM, Togias A. Inflammatory cellular influx follows capsaicin nasal challenge. Am J Respir Crit Care Med 1996;153:1222-9.
19. McLean S, Ganong A, Seymour PA, Bryce DK, Crawford RT, Morrone J, et al. Characterization of CP-122,721: a nonpeptide antagonist of the neurokinin NK1 receptor. J Pharmacol Exp Ther 1996;277:900-8.
20. Kudlacz EM, Shatzer SA, Knippenberg RW, Logan DE, Poirot M, van-Giersbergen PL, et al. In vitro and in vivo characterization of MDL 105, 212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist. J Pharmacol Exp Ther 1996;277:840-51.
21. Lowe JA III. Nonpeptide tachykinin antagonists: medicinal chemistry and molecular biology. Med Res Rev 1996;16:527-45.
22. Gitter BD, Bruns RF, Howbert JJ, Waters DC, Threlkeld PG, Cox LM, et al. Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist. J Pharmacol Exp Ther 1995;275:737-44.
23. Giardina GAM, Sarau HM, Farina C, Medhurst AD, Grugni M, Foley JJ, et al. 2-Phenyl-4-quinoline carboxamides: a novel class of potent and selective non-peptide competitive antagonists for the human neurokinin-3 receptor. J Med Chem 1996;39:2281-4.
24. Canning BJ, Undem BJ. Evidence that antidromically stimulated vagal afferents activate inhibitory neurones innervating guinea-pig trachealis. J Physiol 1994;480:613-25.
25. Dickenson AH, Dray A. Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception. Br J Pharmacol 1991;104:1045-9.
26. Santicioli P, Del Bianco E, Figini M, Bevan S, Maggi CA. Effect of capsazepine on the release of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) induced by low pH, capsaicin and potassium in rat soleus muscle. Br J Pharmacol 1993;110:609-12.
27. Noguchi K, Ruda MA. Gene regulation in an ascending nociceptive pathway: inflammation-induced increase in preprotachykinin mRNA in rat lamina I spinal projection neurons. J Neurosci 1992;12:2563-72.
28. Fischer A, McGregor G, Saria A, Philippin B, Kummer W. Induction of tachykinin gene and peptide expression in guinea pig nodose primary afferent neurons by allergic airway inflammation. J Clin Invest 1996;98:2284-91.
29. McCarson KE, Krause JE. NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociception. J Neurosci 1994;14:712-20.
30. Riccio MM, Myers AC, Undem BJ. Immunomodulation of afferent neurons in guinea-pig isolated airway. J Physiol 1996;491:499-509.