In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist

Journal of Pharmacology and Experimental Therapeutics

Volumn 277, Issue 2, 1996, Pages 840-851

  Kudlacz, Elizabeth M ^a   Shatzer, Scott A ^a   Knippenberg, Robert W ^a   Logan, Deborah E ^a   Poirot, Matthieu ^a   Van Giersbergen, Paul L M ^a   Burkholder, Timothy P ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; CAPSAICIN; MDL 105212A; TACHYKININ RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; EXTRAVASATION; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; NONHUMAN; PATHOGENESIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; STIMULUS RESPONSE; SWINE; VASODILATATION;

AMINO ACID SEQUENCE; ANIMALS; ASTHMA; BRONCHOCONSTRICTION; CAPILLARY PERMEABILITY; GUINEA PIGS; HUMANS; INOSITOL PHOSPHATES; MALE; METHACHOLINE CHLORIDE; MICE; MOLECULAR SEQUENCE DATA; NEUROKININ A; PIPERIDINES; PYRROLIDINES; RATS; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-2; RESPIRATION; SPECIES SPECIFICITY; SUBSTANCE P;

EID: 0030431038     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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