메뉴 건너뛰기




Volumn 52, Issue 5, 1996, Pages 464-468

Is there a critical tissue oxygen tension for bioenergetic status and cellular pH regulation in solid tumors?

Author keywords

31P nuclear magnetic resonance spectroscopy; Critical O2 tension; Tumor acidosis; Tumor ATP; Tumor bioenergetic status; Tumor hypoxia; Tumor oxygenation; Tumor pH

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; LACTIC ACID; PHOSPHATE;

EID: 0029940284     PISSN: 00144754     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01919317     Document Type: Short Survey
Times cited : (19)

References (33)
  • 3
    • 0021241350 scopus 로고
    • The application of nuclear magnetic resonance to the study of cellular physiology
    • Balaban, R. S., The application of nuclear magnetic resonance to the study of cellular physiology. Am. J. Physiol. 246 (1984) C10-C19.
    • (1984) Am. J. Physiol. , vol.246
    • Balaban, R.S.1
  • 4
    • 0026666825 scopus 로고
    • Microsphere and dilution techniques for the determination of blood flows and volumes in conscious mice
    • Barbee, R. W., Perry, B. D., Ré, R. N., and Murgo, J. P., Microsphere and dilution techniques for the determination of blood flows and volumes in conscious mice. Am. J. Physiol. 263 (1992) R728-R733.
    • (1992) Am. J. Physiol. , vol.263
    • Barbee, R.W.1    Perry, B.D.2    Ré, R.N.3    Murgo, J.P.4
  • 5
    • 0021828791 scopus 로고
    • Investigation of adenylate energy charge, phosphorylation potential and ATP concentration in cells stressed with starvation and heat
    • Calderwood, S. K., Bump, E. A., Stevenson, M. A., Van Kersen, I. and Hahn, G. M., Investigation of adenylate energy charge, phosphorylation potential and ATP concentration in cells stressed with starvation and heat. J. Cell. Physiol. 124 (1985) 261-268.
    • (1985) J. Cell. Physiol. , vol.124 , pp. 261-268
    • Calderwood, S.K.1    Bump, E.A.2    Stevenson, M.A.3    Van Kersen, I.4    Hahn, G.M.5
  • 9
    • 0026750254 scopus 로고
    • Energy status in the murine FSaII and MCaIV tumors under aerobic and hypoxic conditions: An in-vivo and in-vitro analysis
    • Gerweck, L. E., Koutcher, J. A., Zaidi, S. T. H., and Seneviratne, T., Energy status in the murine FSaII and MCaIV tumors under aerobic and hypoxic conditions: an in-vivo and in-vitro analysis. Int. J. Radial. Oncol. Biol. Phys. 23 (1992) 557-561.
    • (1992) Int. J. Radial. Oncol. Biol. Phys. , vol.23 , pp. 557-561
    • Gerweck, L.E.1    Koutcher, J.A.2    Zaidi, S.T.H.3    Seneviratne, T.4
  • 10
    • 0027328525 scopus 로고
    • Energy status and radiological hypoxia at specified oxygen concentrations
    • Gerweck, L. E., Seneviratne, T., and Gerweck, K. K., Energy status and radiological hypoxia at specified oxygen concentrations. Radiat. Res. 135 (1993) 69-74.
    • (1993) Radiat. Res. , vol.135 , pp. 69-74
    • Gerweck, L.E.1    Seneviratne, T.2    Gerweck, K.K.3
  • 11
    • 0024513662 scopus 로고
    • Relationship between energy status, hypoxic cell fraction and hyperthermic sensitivity in a murine fibrosarcoma
    • Gerweck, L. E., Urano, M., Koutcher, J., Fellenz, M. P., and Kahn, J., Relationship between energy status, hypoxic cell fraction and hyperthermic sensitivity in a murine fibrosarcoma. Radiat. Res. 117 (1989) 448-458.
    • (1989) Radiat. Res. , vol.117 , pp. 448-458
    • Gerweck, L.E.1    Urano, M.2    Koutcher, J.3    Fellenz, M.P.4    Kahn, J.5
  • 12
    • 0026356726 scopus 로고
    • Oxygenation of carcinomas of the uterine cervix: Evaluation of computerized O, tension measurements
    • Hoeckel, M., Schlenger, K., Knoop, C., and Vaupel, P., Oxygenation of carcinomas of the uterine cervix: evaluation of computerized O, tension measurements. Cancer Res. 51 (1991) 6098-6102.
    • (1991) Cancer Res. , vol.51 , pp. 6098-6102
    • Hoeckel, M.1    Schlenger, K.2    Knoop, C.3    Vaupel, P.4
  • 14
    • 0025275521 scopus 로고
    • Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy and cryospectrophotometry
    • Mueller-Klieser, W., Schaefer, C., Walenta, S., Rofstad, E. K., Fenton, B. M., and Sutherland, R. M., Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy and cryospectrophotometry. Cancer Res. 50 (1990) 1681-1685.
    • (1990) Cancer Res. , vol.50 , pp. 1681-1685
    • Mueller-Klieser, W.1    Schaefer, C.2    Walenta, S.3    Rofstad, E.K.4    Fenton, B.M.5    Sutherland, R.M.6
  • 18
    • 0023820074 scopus 로고
    • 31P NMR spectroscopy measurements of human ovarian carcinoma xenografts: Relationship to tumor volume, growth rate, necrotic fraction and differentiation status
    • 31P NMR spectroscopy measurements of human ovarian carcinoma xenografts: relationship to tumor volume, growth rate, necrotic fraction and differentiation status. Radiother. Oncol. 12 (1988) 315-326.
    • (1988) Radiother. Oncol. , vol.12 , pp. 315-326
    • Rofstad, E.K.1    De Muth, P.2    Sutherland, R.M.3
  • 19
    • 0023821418 scopus 로고
    • 31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia
    • 31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia. Cancer Res. 48 (1988) 5440-5446.
    • (1988) Cancer Res. , vol.48 , pp. 5440-5446
    • Rofstad, E.K.1    De Muth, P.2    Fenton, B.M.3    Sutherland, R.M.4
  • 24
    • 0024379967 scopus 로고
    • Acid pH in tumors and its potential for therapeutic exploitation
    • Tannock, I. F., and Rotin, D., Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res. 49 (1989) 4373-4384.
    • (1989) Cancer Res. , vol.49 , pp. 4373-4384
    • Tannock, I.F.1    Rotin, D.2
  • 25
    • 0023134534 scopus 로고
    • Energy metabolism and blood perfusion in a mouse mammary adenocarcinoma during growth and following X irradiation
    • Tozer, G.,. Suit, H. D., Barlai-Kovach, M., Brunengraber, H., and Biaglow, J., Energy metabolism and blood perfusion in a mouse mammary adenocarcinoma during growth and following X irradiation. Radiat. Res. 109 (1987) 275-293.
    • (1987) Radiat. Res. , vol.109 , pp. 275-293
    • Tozer, G.1    Suit, H.D.2    Barlai-Kovach, M.3    Brunengraber, H.4    Biaglow, J.5
  • 26
    • 0026919666 scopus 로고
    • 31P MRS observations of tumors energy metabolism
    • 31P MRS observations of tumors energy metabolism. NMR Biomed. 5 (1992) 279-289.
    • (1992) NMR Biomed. , vol.5 , pp. 279-289
    • Tozer, G.M.1    Griffiths, J.R.2
  • 27
    • 0002972851 scopus 로고
    • Oxygenation of solid tumors
    • Ed. B. A. Teicher, Marcel Dekko, New York
    • Vaupel, P., Oxygenation of solid tumors, in: Drug Resistance in Oncology, pp. 53-85. Ed. B. A. Teicher, Marcel Dekko, New York 1993.
    • (1993) Drug Resistance in Oncology , pp. 53-85
    • Vaupel, P.1
  • 28
    • 0026920895 scopus 로고
    • Physiological properties of malignant tumors
    • Vaupel, P., Physiological properties of malignant tumors NMR Biomed. 5 (1992) 220-225.
    • (1992) NMR Biomed. , vol.5 , pp. 220-225
    • Vaupel, P.1
  • 29
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel, P., Kallinowski, F., and Okunieff, P., Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res. 49 (1989) 6449-6465
    • (1989) Cancer Res. , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 33
    • 0027062852 scopus 로고
    • Pixel-to-pixel correlation between images of absolute ATP concentrations and blood flow in tumors
    • Walenta, S., Dellian, M., Goetz, A. E., Kuhnle, G. E. H., and Mueller-Klieser, W., Pixel-to-pixel correlation between images of absolute ATP concentrations and blood flow in tumors, Br. J. Cancer 66 (1992) 1099-1102.
    • (1992) Br. J. Cancer , vol.66 , pp. 1099-1102
    • Walenta, S.1    Dellian, M.2    Goetz, A.E.3    Kuhnle, G.E.H.4    Mueller-Klieser, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.