SCOPUS 정보 검색 플랫폼

Pharmaceutical Research

Volumn 14, Issue 2, 1997, Pages 169-175

Effect of restricted conformational flexibility on the permeation of model hexapeptides across caco-2 cell monolayers

(5) Okumu, Franklin W a Pauletti, Giovanni M a Vander Velde, David G a Siahaan, Teruna J a Borchardt, Ronald T a

a UNIVERSITY OF KANSAS (United States)

Author keywords

Caco 2 cells; CD; Conformation; Membrane permeability; NMR; Peptide delivery

Indexed keywords

CYCLOPEPTIDE; HEXAPEPTIDE; SYNTHETIC PEPTIDE;

ARTICLE; ARTIFICIAL MEMBRANE; CELL CULTURE; CELL STRAIN CACO 2; CIRCULAR DICHROISM; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE ABSORPTION; LIPOPHILICITY; MEMBRANE PERMEABILITY; MODEL; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CIRCULAR DICHROISM; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; OLIGOPEPTIDES; PERMEABILITY; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030951009 PISSN: 07248741 EISSN: None Source Type: Journal
DOI: 10.1023/A:1012092409216 Document Type: Article

Times cited : (78)

References (31)

1
- 34447497393
- N. C. Wrighton, F. X. Farrell, R. Chang, A. K. Kashyap, F. P. Barbone, L. S. Mulcahy, D. L. Johnson, R. W. Barett, L. K. Jolliffe, and W. J. Dower. Science 273:397-544 (1996).
- (1996) Science , vol.273 , pp. 397-544
- Wrighton, N.C.¹ Farrell, F.X.² Chang, R.³ Kashyap, A.K.⁴ Barbone, F.P.⁵ Mulcahy, L.S.⁶ Johnson, D.L.⁷ Barett, R.W.⁸ Jolliffe, L.K.⁹ Dower, W.J.¹⁰

2
- 0030222256
- G. M. Pauletti, S. Gangwar, G. T. Knipp, M. M. Nerurkar, F. W. Okumu, K. Tamura, T. J. Siahaan, and R. T. Borchardt. J. Controlled Release 41:3-17 (1996).
- (1996) J. Controlled Release , vol.41 , pp. 3-17
- Pauletti, G.M.¹ Gangwar, S.² Knipp, G.T.³ Nerurkar, M.M.⁴ Okumu, F.W.⁵ Tamura, K.⁶ Siahaan, T.J.⁷ Borchardt, R.T.⁸

3
- 0000888476
- V. H. L. Lee (ed.), Marcel Dekker, New York
- V. H. L. Lee, R. D. Traver, and M. E. Taub, in: V. H. L. Lee (ed.), Peptide and Protein Drug Delivery, Marcel Dekker, New York, 1991, pp. 303-357.
- (1991) Peptide and Protein Drug Delivery , pp. 303-357
- Lee, V.H.L.¹ Traver, R.D.² Taub, M.E.³

4
- 0002604431
- S. S. Davis, L. Illum and E. Tomlinson (eds.), Plenum Press, New York
- M. J. Humphrey. in: S. S. Davis, L. Illum and E. Tomlinson (eds.), Delivery Systems for Peptide Drugs, Plenum Press, New York, 1986, pp. 139-151.
- (1986) Delivery Systems for Peptide Drugs , pp. 139-151
- Humphrey, M.J.¹

5
- 0028239031
- X. H. Zhou. J. Controlled Release 29:239-252 (1994).
- (1994) J. Controlled Release , vol.29 , pp. 239-252
- Zhou, X.H.¹

6
- 0002742177
- P. Krogsgaard-Larsen and H. Bundgaard (eds.), Harwood Academic Publishers, Langhorne
- J. P. Yevich. in: P. Krogsgaard-Larsen and H. Bundgaard (eds.), A Textbook of Drug Design and Development, Harwood Academic Publishers, Langhorne, 1991, pp. 606-630.
- (1991) A Textbook of Drug Design and Development , pp. 606-630
- Yevich, J.P.¹

7
- 0002661982
- V. Pliska, B. Testa and H. Van de Waterbeemd (eds.), VCH, Weinheim
- R. A. Conradi, P. S. Burton, and R. T. Borchardt. in: V. Pliska, B. Testa and H. Van de Waterbeemd (eds.), Lipophilicity in Drug Action and Toxicology, VCH, Weinheim, 1996, pp. 233-250.
- (1996) Lipophilicity in Drug Action and Toxicology , pp. 233-250
- Conradi, R.A.¹ Burton, P.S.² Borchardt, R.T.³

8
- 0026513211
- R. A. Conradi, A. R. Hilgers, N. F. H. Ho, and P. S. Burton. Pharm. Res. 9:435-439 (1992).
- (1992) Pharm. Res. , vol.9 , pp. 435-439
- Conradi, R.A.¹ Hilgers, A.R.² Ho, N.F.H.³ Burton, P.S.⁴

9
- 0026535563
- P. S. Burton, R. A. Conradi, A. R. Hilgers, N. F. H. Ho, and L. L. Maggiora. J. Controlled Release 19:87-93 (1992).
- (1992) J. Controlled Release , vol.19 , pp. 87-93
- Burton, P.S.¹ Conradi, R.A.² Hilgers, A.R.³ Ho, N.F.H.⁴ Maggiora, L.L.⁵

10
- 0027509507
- J. Drewe, G. Fricker, J. Vonderscher, and C. Beglinger. Br. J. Pharmacol. 108:298-303 (1993).
- (1993) Br. J. Pharmacol. , vol.108 , pp. 298-303
- Drewe, J.¹ Fricker, G.² Vonderscher, J.³ Beglinger, C.⁴

11
- 0025224640
- S. Lundin and P. Artursson. Int. J. Pharm. 64:181-186 (1990).
- (1990) Int. J. Pharm. , vol.64 , pp. 181-186
- Lundin, S.¹ Artursson, P.²

12
- 0027265014
- D. T. Thwaites, B. H. Hirst, and N. L. Simmons. Pharm. Res. 10:674-681 (1993).
- (1993) Pharm. Res. , vol.10 , pp. 674-681
- Thwaites, D.T.¹ Hirst, B.H.² Simmons, N.L.³

13
- 0030951009
- G. M. Pauletti, F. W. Okumu, and R. T. Borchardt. Pharm. Res. 14:169-175 (1997).
- (1997) Pharm. Res. , vol.14 , pp. 169-175
- Pauletti, G.M.¹ Okumu, F.W.² Borchardt, R.T.³

14
- 8044244255
- G. T. Knipp, N. F. H. Ho, C. L. Barsuhn, and R. T. Borchardt. Pharm. Res. 12:S-302 (1995).
- (1995) Pharm. Res. , vol.12
- Knipp, G.T.¹ Ho, N.F.H.² Barsuhn, C.L.³ Borchardt, R.T.⁴

15
- 0028080058
- A. Adson, T. J. Raub, P. S. Burton, C. L. Barsuhn, A. R. Hilgers, K. L. Audus, and N. F. H. Ho. J. Pharm. Sci. 83:1529-1536 (1994).
- (1994) J. Pharm. Sci. , vol.83 , pp. 1529-1536
- Adson, A.¹ Raub, T.J.² Burton, P.S.³ Barsuhn, C.L.⁴ Hilgers, A.R.⁵ Audus, K.L.⁶ Ho, N.F.H.⁷

16
- 0028363125
- D. Barlow and T. Satoh. J Controlled Release 29:283-291 (1994).
- (1994) J Controlled Release , vol.29 , pp. 283-291
- Barlow, D.¹ Satoh, T.²

17
- 0024593744
- I. J. Hidalgo, T. J. Raub, and R. T. Borchardt. Gastroenterology 96:736-749 (1989).
- (1989) Gastroenterology , vol.96 , pp. 736-749
- Hidalgo, I.J.¹ Raub, T.J.² Borchardt, R.T.³

18
- 0030470532
- G. M. Pauletti, S. Gangwar, F. W. Okumu, T. J. Siahaan, V. J. Stella, and R. T. Borchardt. Pharm. Res. 13:1615-1623 (1996).
- (1996) Pharm. Res. , vol.13 , pp. 1615-1623
- Pauletti, G.M.¹ Gangwar, S.² Okumu, F.W.³ Siahaan, T.J.⁴ Stella, V.J.⁵ Borchardt, R.T.⁶

19
- 45949123116
- H. Rink. Tetrahedron Lett. 28:3787-3790 (1987).
- (1987) Tetrahedron Lett. , vol.28 , pp. 3787-3790
- Rink, H.¹

20
- 33845557921
- G. Lu, S. Mojsov, J. P. Tam, and R. B. Merrifield. J. Org. Chem. 46:3433-3436 (1981).
- (1981) J. Org. Chem. , vol.46 , pp. 3433-3436
- Lu, G.¹ Mojsov, S.² Tam, J.P.³ Merrifield, R.B.⁴

21
- 0011850124
- J. Diago-Meseguer and A. L. Palomo-Coll. Synthesis 1980:547-551 (1980).
- (1980) Synthesis , vol.1980 , pp. 547-551
- Diago-Meseguer, J.¹ Palomo-Coll, A.L.²

22
- 0011312149
- S. Gangwar, S. D. S. Jois, T. J. Siahaan, D. G. Vander Velde, V. J. Stella, and R. T. Borchardt. Pharm. Res. 13:1655-1660 (1996).
- (1996) Pharm. Res. , vol.13 , pp. 1655-1660
- Gangwar, S.¹ Jois, S.D.S.² Siahaan, T.J.³ Vander Velde, D.G.⁴ Stella, V.J.⁵ Borchardt, R.T.⁶

23
- 0031041493
- G. M. Pauletti, S. Gangwar, B. Wang, and R. T. Borchardt. Pharm. Res. 14: 11-17 (1997).
- (1997) Pharm. Res. , vol.14 , pp. 11-17
- Pauletti, G.M.¹ Gangwar, S.² Wang, B.³ Borchardt, R.T.⁴

24
- 0002439879
- V. J. Hruby (ed.), Academic Press, New York
- R. W. Woody. in: V. J. Hruby (ed.), The Peptides, Academic Press, New York, 1985, pp. 15-114.
- (1985) The Peptides , pp. 15-114
- Woody, R.W.¹

25
- 0003919736
- John Wiley & Sons, New York
- K. Wüthrich, NMR of Proteins and Nucleic Acids, John Wiley & Sons, New York (1986).
- (1986) NMR of Proteins and Nucleic Acids
- Wüthrich, K.¹

26
- 49349130990
- V. F. Bystrov. Progr. NMR Spectrosc. 10:41-81 (1976).
- (1976) Progr. NMR Spectrosc. , vol.10 , pp. 41-81
- Bystrov, V.F.¹

27
- 0028903847
- K. D. Fine, C. A. Santa Ana, J. L. Portes, and J. S. Fordtran. Gastroenterology 108:983-989 (1995).
- (1995) Gastroenterology , vol.108 , pp. 983-989
- Fine, K.D.¹ Santa Ana, C.A.² Portes, J.L.³ Fordtran, J.S.⁴

28
- 0001516454
- F. W. Okumu, G. M. Pauletti, D. G. Vander Velde, T. J. Siahaan, and R. T. Borchardt. Pharm. Res. 12:S-302 (1995).
- (1995) Pharm. Res. , vol.12
- Okumu, F.W.¹ Pauletti, G.M.² Vander Velde, D.G.³ Siahaan, T.J.⁴ Borchardt, R.T.⁵

29
- 0001057444
- G. M. Pauletti, F. W. Okumu, D. G. Vander Velde, and R. T. Borchardt. Pharm. Res. 13:S-235 (1996).
- (1996) Pharm. Res. , vol.13
- Pauletti, G.M.¹ Okumu, F.W.² Vander Velde, D.G.³ Borchardt, R.T.⁴

30
- 0028321502
- J. Hochman and P. Artursson. J. Controlled Release 29:253-267 (1994).
- (1994) J. Controlled Release , vol.29 , pp. 253-267
- Hochman, J.¹ Artursson, P.²

31
- 0023521841
- J. R. Pappenheimer and K. Z. Reiss. J. Memb. Biol. 100:123-136 (1987).
- (1987) J. Memb. Biol. , vol.100 , pp. 123-136
- Pappenheimer, J.R.¹ Reiss, K.Z.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.