Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1- aminobenzotriazole to products that covalently bind with protein in Guinea pig liver and lung microsomes: Comparative study with 1-aminobenzotriazole

Chemical Research in Toxicology

Volumn 10, Issue 5, 1997, Pages 589-599

  Woodcroft, Kimberley J ^a   Webb, Chris D ^a   Yao, Ming ^a   Weedon, Alan C ^a   Bend, John R ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME MECHANISM; ENZYME POLYMORPHISM; ENZYME SUBSTRATE; LIVER MICROSOME; NONHUMAN; PROTEIN BINDING; PROTEIN MODIFICATION;

ANIMALS; BIOTRANSFORMATION; CARBON RADIOISOTOPES; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GUINEA PIGS; LUNG; MALE; MICROSOMES; MICROSOMES, LIVER; PROTEIN BINDING; TRIAZOLES;

ANIMALIA; CAVIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0030950352     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx960185g     Document Type: Article

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