Cell types of the airway epithelia - Morphology, molecular biology, and clinical implications;Zelltypen der Atemwegsepithelien: Morphologie, Molekularbiologie und klinische Bedeutung

Pneumologie

Volumn 51, Issue 2, 1997, Pages 142-149

  Bals, R ^a,b,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b Anatomische Anstalt   (Germany)

^c WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASTHMA; BASAL CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TYPE; CILIATED EPITHELIUM; CLARA CELL; CYSTIC FIBROSIS; DEFENSE MECHANISM; GENE THERAPY; GOBLET CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; LOWER RESPIRATORY TRACT; MOLECULAR BIOLOGY; MUCOCILIARY CLEARANCE; MUCOUS CELL; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT CANCER; SECRETORY CELL; WOUND HEALING;

EID: 0030933074     PISSN: 09348387     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (79)

1. Alberts, B., D. Dray, J. Lewis, M. Raff, K. Roberts, J. D. Watson: Cilia and Centrioles. In: Molecular biology of the cell. 3. Ausgabe, Garland Publishing. New York, London 1994, S. 815-820
2. Audie, J. P., A. Janin, N. Porchert, M. C. Copin, B. Gosselin, J. P. Aubert: Expression of human mucin genes in respiratory, digestive, and reproductive tract ascertained by in situ hybridization. J. Histochem. Cytochem. 41 (1993) 1479-1485
3. Ayers, M. M., P. K. Jeffery: Proliferation and differentiation in mammalian airway epithelium. Eur. Respir. J. 1 (1988) 58-80
4. Baldwin, F.: Basal cells in human bronchial epithelium. Anat. Rec. 238 (1994) 260-367
5. Bals, R., U. Schumacher, U. Welsch, R. M. Huber: Lectin binding sites of human bronchial mucins dependent on the ABO blood group. In: Van Driessche, E., H. Franz, S. Beeckmans, U. Pfüller, A. Kallikorm, T. C. Bog-Hansen (Hrsg.): Lectins: Biology, Biochemistry, Clinical Biochemistry - Volume 8, Textop, Hellerup 1993, S. 348
6. Bals, R., U. Welsch: Lectins and antibodies against blood group antigens as tools to study the cellular source of glycoproteins in the human bronchial fluid - a comparison of morphological and biochemical observations. Cell Tiss. Res. 286 (1996) 457-465
7. Barnes, P. J.: Neural control of human airways in health and disease. Am. Rev. Respir. Dis. 134 (1986) 1289-1293
8. Berkman, N., A. Robichaud, V. L. Krishnan, G. Roesems, R. Robbins, P. J. Jose, P. J. Barnes, K. F. Chung: Expression of RANTES in human airway epithelial cells: effect of corticosteroids and interleukin-4, -10 and -13. Immunology 87 (1996) 599-603
9. Bowden, D. H.: Cell turnover in the lung. Am. Rev. Respir. Dis. 128 (1983) S46-S48
10. Bowes, D., A. E. Clark, B. Corrin: Ultrastructural localization of lactoferrin and glycoprotein in human bronchial glands. Thorax 36 (1981) 108-115
11. Brandtzaeg, P.: Mucosal and glandular distribution of immunoglobulin components. Immunology 26 (1974) 1101-1114
12. Cetin, Y., H. Kulaksiz, P. Redecker, G. Bargsten, K. Adermann, D. Grube, W. G. Forssmann: Bronchiolar nonciliated secretory (Clara) cells: source of guanylin in the mammalian lung. PNAS 92 (1995) 5925-5929
13. Curiel, D. T., J. M. Pilcwski, S. M. Albelda: Gene therapy approaches for inherited and acquired lung diseases. Am. J. Respir. Cell. Mol. Biol. 14 (1996) 1-18
14. De Water, R., L. N. A. Willems, G. N P. Van Muijen, C. Franken, J. A. M. Fransen, J. H. Dijkman, J. A. Kramps: Ultrastructural localization of bronchial antileukoprotease in central and peripheral human airways by a gold-labeling technique using monoclonal antibodies. Am. Rev. Respir. Dis. 133 (1985) 882-890
15. Devereux, T. R., B. A. Domin, R. M. Philpot: Xenobiotic metabolism by isolated pulmonary cells. Pharmacol. Ther. 41 (1989) 243 -256
16. Dohrman, A., T. Tsuda, E. Escudier, M. Cardone, B. Jany, J. Gum, Y. Kim, C Basbaum: Distribution of lysozyme and mucin (MUC2 and MUC3) mRNA in human bronchus. Experimental Lung Res. 20 (1994) 367-380
17. Ellefsen, P., M. Tos: Goblet cells in the human trachea. Arch. Otolaryng. 95 (1972) 547-555
18. Engelhardt, J. F., H. Schlossberg, J. R. Yankaskas, L Dudus: Progenitor cells of the adult human airways involved in submucosal gland development. Development 121 (1995) 2031-2046
19. Engelhardt, J. F., J. R. Yankaskas, S. A. Ernst, Y. Yang, C. R. Marino, R. C. Boucher, J. A. Cohn, J. M. Wilson: Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nature genetics 2 (1992) 240-248
20. Evans, M. J., L. J. Cabral-Anderson, G. Freeman: Role of the clara cell in renewal of the bronchiolar epithelium. Lab. Invest. 38 (1978) 648-655
21. Evans, M. J., P. C. Moller: Biology of airway basal cells. Exp. Lung Res. 17 (1991) 513-531
22. Evans, M. J., C. G. Plopper: The role of basal cells in adhaesion of columnar epithelium to airway basement membrane. Am. Rev. Respir. Dis. 138 (1988) 481-483
23. Evans, M. J. R. A. Cox, S. G. Shami, B. Wilson, C. G. Plopper: The role of basal cells in attachment of columnar cells to the basal lamina of the trachea. Am. J. Respir. Cell Mol. Biol. 1 (1989) 463 -469
24. Franken, C., C. J. L. M. Meijer, J. H. Dijkman: Tissue distribution of antileukoprotease and lysozyme in humans. J. Histochem. Cytochem. 35 (1989) 493-498
25. Gendler, S. J., A. P. Spicer: Epithelial mucin genes. Ann. Rev. Physiol. 57 (1995) 607-634
26. Guo, F. H., H. R. De Raevc, T. W. Rice, D. J. Stuehr, F. B. Thunnissen, S. C. Rrzurum: Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airways. PNAS 92 (1995) 7809-7813
27. Hage, E., J. Hage, G. Juel: Endocrine-like cells of the pulmonary epithelium of the human adult lung. Cell Tiss. Res. 178 (1973) 39-43
28. Hance, A. J.: Pulmonary immune cells in health and disease: dendritic cells and Langerhans' cells. Eur. Respir. J. 6 (1993) 1213 -1229
29. Hovenberg, H. W., J. R. Davies, K. Carlstedtl: Different mucins are produced by the surface epithelium and the submucosa in human trachea: identification of MUC5AC as a major mucin from the goblet cells. Biochem. J. 318 (1996) 319-324
30. Inayama, Y., G. E. Hook, A. R. Brody, A. M. Jetten, T. Gray, J. Mahler, P. Nettesheim: In vitro and in vivo growth and differentiation of clones of tracheal basal cells. Am. J. Pathol. 134 (1989) 539-549
31. Jacquot, J., E. Puchelle, J. Hinnrasky, C. Fuchey, C. Bettinger, C. Spilmont, N. Bonnet, A. Dieterle, D, Dreyer, A. Pavirani, W. Dalemans: Localisatzion of the cystic fibrosis transmembrane conductance regulator in airway secretory glands. Eur. Respir. J. 6 (1993) 169-176
32. Jany, B., C. B. Basbaum: Modification of mucin gene expression in airway disease. Am. Rev. Respir. Dis. 144 (suppl.) (1991) S38 -S41
33. Jeffery, P. K., L. Reid: New observation of rat airway epithelium: A Quantitative and Electron Microscopic Study. J. Anat. 120 (1975) 295-320
34. Jeffery, P. K.: Microscopic structure of normal lung. In: Brewis, R. A. L., B. Corrin, D. M. Geddes, G. J. Gibson (Hrsg.): Respiratory Medicine, 2. Auflage. Saunders, Sondon 1995, S. 54-72
35. Jeffery, P. K.: Morphologic features of airway surface epithelial cells and glands. Am. Rev. Resp. Dis. 128 (1983) S14-S20
36. Joos, G. F., P. R. Germonpre, J. C. Kips, R. A. Peleman, R. A. Pauwels: Sensory neuropeptides and the human lower airways: presentstates and future directions. Eur. Respir. J. 7 (1994) 1161 -1171
37. Kauffmann, F., C. Frette, Q.-T. Pham, S. Natissi, J.-P. Bertrand, R. Oriol: Associations of blood group-related antigens to FEV, wheezing and asthma. Am. J. Respir. Crit. Med. 153 (1996) 76-87
38. Kauffmann, S. L.: Cell proliferation in the lung. Int. Rev. Exper. Path. 22 (1980) 131-191
39. Kroegel, C., J.-C. Virchow, Jr., W. Luttmann, C. Walker, J. A. Warner: Pulmonary immune cells in health and disease: the eosinophil leucocyte (part I). Eur. Respir. J. 7 (1994) 519-543
40. Kroegel, C., J. A. Warner, J.-C. Virchow Jr., H. Matthys: Pulmonary immune cells in health and disease: the eosinophil leucocyte (part II). Eur. Respir. J. 7 (1994) 743-760
41. Lauweryns, J. M., V. De Bock, A. A. J. Verhofstad, H. W. M. Steinbusch: Immunohistochemical localization of serotonin in intrapulmonary neuro-epithelial bodies. Cell Tiss. Res. 226 (1982) 215-221
42. Leigh, M. W., J. E. Kylander, J. R. Yankaskas, R. C Boucher: Cell proliferation in bronchial epithelium and submucosal glands of cystic fibrosis patients. Am. J. Respir. Cell. Mol. Biol. 12 (1995) 605-612
43. Levine, S. J.: Bronchial epithelial cell-cytokine interactions in airway inflammation. J. Invest. Med. 43 (1996) 241-249
44. Liu. J. Y., P. Nettesheim, S. H. Randell: Growth and differentiation of tracheal epithelial progenitor cells. Am. J. Physiol. 266 (1994) L296-L307
45. Massaro, G. D., G. Singh, R. Mason, C. G. Plopper, A. M. Malkinson, D. B. Gail: Biology of the Clara cell. Am. J. Physiol. 266 (1994) L101-L106
46. Mazzuca, M., M. Lhermitte, J.-J. Lafitte, P. Roussel: Use of lectins for detection of glycoconjugates in the glandular cells of the human bronchial mucosa. J. Histochem. Cytochem. 30 (1982) 959 -966
47. McDowell, E. M., L A. Barrett, F. Glavin, C. C. Harris, B. F. Trump: The respiratory epithelium. I. human bronchus. J. Natl. Cancer Inst. 61 (1978) 539-555
48. McWilliam, A. S., D. J. Nelson, P. G. Holt: The biology of airway dendritic cells. Immun. Cell. Biol. 73 (1995) 405-413
49. Mercer, R. R., M. L. Russell, V. L Roggli, J. D. Crapo: Cell number and distribution in human and rat airways. Am. J. Respir. Cell. Mol. Biol. 10 (1994) 613-624
50. Meyrick, B., L. Reid: Ultrastructure of cells in the human bronchial submucosal glands. J. Anat. 107 (1970) 281-299
51. Meyrick, B., J. M. Sturgess, L. Reid: A reconstruction of the duct system and secretory tubules of the human bronchial submucosal glands. Thorax 24 (1969) 729-736
52. Montefort, S., S.T. Holgate, P. H. Howarth: Leococyte-endothelial adhesion molecules and their role in bronchial asthma and allergic rhintis. Eur. Respir. J. 6 (1993) 1044-1054
53. Mooren, H. W. D., C. J. L. M. Meyer, A. J. Kramps, C. Franken, J. H. Dijkman: Ultrastructural localization of the low molecular weight protease inhibitor in human bronchial glands. J. Histochem. Cytochem. 30 (1982) 1130-1134
54. Nakamura, Y., L. Tate, R. F. Ertl., M. Kawamoto, T. Mio, Y. Adachi, D. J. Romberger, S. Koizumi, G. Grossman, R. A. Robbins: Bronchial epithelial cells regulate fibroblast proliferation. Am. J. Physiol. 269 (1995) L377-387
55. Nishi, K., G. Fechner, S. Rand, B. Brinkmann: Light-microscopic examination of ABH and Lewis antigens in human tracheal and epiglottic glands using the avidin-biotin-peroxidase complex technique. Z. Rechtsmed. 102 (1989) 255-262
56. Pabst, R., T. Tschernig: Lymphocytes in the lung: an often neglected cell. Anat. Embryol. 192 (1995) 293-299
57. Perini, J.-M., T. Marianne, J.-J. Lafitte, G. Lamblin, P. Roussel, M. Mazuca: Use of an antiserum against deglycosylated human mucins for cellular localization of their peptide precursors: antigenic similarities between bronchial and intestinal mucins. J. Histochem. Cytochem. 37 (1989) 869-875
58. Pilewski, J. M., S. M. Albeida: Adhesion molecules in the lung. Am. Rev. Respir. Dis. 148 (suppl.) (1993) S31-S37
59. Raeburn, D., S. E. Webber: Proinflammatory potential of the airway epithelium in bronchial asthma. Eur. Respir. J. 7 (1994) 2226 -2233
60. Rhodin, J. A. G.: The ciliated cell: ultrastructure and function of the human tracheal mucosa. Am. Rev. Respir. Dis. 93 (1966) 1-15
61. Richmond, I., G. E. Pritchard, T. Ashcroft, A. Avery, P. A. Corris, F. H. Walters: Bronchial associated lymphoid tissue (BALT) in human lung: its distribution in smokers and non-smokers. Thorax 48 (1993) 1130-1134
62. Roche, W. R., S. Montefort, J. Baker, S. T. Holgate: Cell adhesion molecules and the bronchial epithelium. Am. Rev. Respir. Dis. 149 (suppl.) (1993) S79-82
63. Rogers, D. F.: Airway goblet cells: responsive and adaptable front-line defenders. Eur. Respir. J. 7 (1994) 1690-1706
64. Rogers, A. V., A. Dear, B. Corrin, P. K. Jeffery: Identification of serous-like cells in the surface epithelium of human bronchioles. Eur. Respir. J. 6 (1993) 496-504
65. Russell, J. P., G. Diamond, A. P. Tarver, T. F. Scanlin, C. L. Bevins: Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha. Infect. Immun. 64 (1996) 1565 -1568
66. Schonwetter, B. S., E. D. Stolzenberg, M. Zasloff: Epithelial antibiotics induced at sites of inflammation. Science 267 (1995) 1645-1648
67. Schulte, B. A., S. S. Spicer. Light microscopic histochemical detection of sugar residues in secretory glycoproteins of rodent and human tracheal glands with lectin-horseradish peroxidase conjugates and the galactose oxidase-Schiff sequence. J. Histochem. Cytochem. 31 (1983) 391-403
68. Reddy, P. M., C. U. Tu, R. Wu: Glutathione S-transferases in tracheobronchial epithelium. Am. J. Physiol. 269 (1995) L473-481
69. Sibille, Y., F.-X. Marchandise: Pulmonary immune cells in health and disease: polymorphonuclear neutrophils. Eur. Resp. J. 6 (1993) 1529-1543
70. Sleigh, M. A., J. R. Blake, N. Liron: The propulsion of mucus by cilia. Am. Rev. Respir. Dis. 137 (1988) 726-731
71. Smith, M. N., S. D. Greenberg, H. J. Spjut: The Clara cell: a comparative ultrastructural study in mammals. Am. J. Anat. 155 (1979) 15-30
72. Smith, J., J., S. M. Travis, E. P. Greenberg, M. J. Welsh: Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85 (1996) 229-236
73. Strous, G. J., J. Dekker: Mucin-type glycoproteins. Crit. Rev. Biochem. Mol. Biol. 27 (1992) 57-92
74. Thompson, A. B., R. A. Robbins, D. J. Romberger, J. H. Sisson, J. R. Spurzem, H. Teschler, S. I. Rennard: Immunological functions of the pulmonary epithelium. Eur. Respir. J. 8 (1995) 127-149
75. Tos, M.: Mucous glands of the trachea in children. Anat. Anz. 126 (1970) 146-160
76. Verdugo, P.: Goblet cell secretion and mucogenesis. Am. Rev. Physiol. 72 (1990) 159-166
77. Verma, M., E. A. Davidson: Mucin gens: stucture, expression and regulation. Glycoconjugate J. 11 (1994) 172-179
78. Warner, J. A., C. Kroegel: Pulmonary immune cells in health and disease: mast cell and basophils. Eur. Resp. J. 7 (1994) 1326-1341
79. Zepeda, M. L., M. R. Chinoy, J. M. Wilson: Characterization of stem cells in human airway capable of reconstructing a fully differentiated bronchial epithelium. Som. Cell. Mol. Gen. 21 (1995) 61-73