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0343786778
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note
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To the best of our knowledge, only one example on the lithiation of a α-amido sulfone and the subsequent reaction with methyl iodide has been described (reference 1c).
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17
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(a) See, for instance reference 1c.
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23
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This compound was prepared by reaction of p-toluenesulfinic acid with aqueous formaldehyde and N-methylaniline in methanol in 80% yield (see reference 2).
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2O content measured by gas chromatography) does not allow the determination of %D. Thus, calculated %H/D values are corrected considering this fact.
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note
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This work was supported by DGICYT from the Spanish Ministerio de Educación y Ciencia (MEC; projects no. PB94-1514 and PB94-1515). D. A. A., E. A. and D. J. R. thank the MEC for grants.
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