Sequence- and structure-specific determinants in the interaction between the RNA encapsidation signal and reverse transcriptase of avian hepatitis B viruses

Journal of Virology

Volumn 71, Issue 7, 1997, Pages 4971-4980

  Beck, Jürgen ^a   Nassal, Michael ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED DNA POLYMERASE; VIRUS RNA;

ARTICLE; HEPATITIS B VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE ANALYSIS; VIRUS CAPSID; VIRUS MORPHOLOGY;

EID: 0030908648     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.7.4971-4980.1997     Document Type: Article

References (40)

1. Allain, F. H., C. C. Gubser, P. W. Howe, K. Nagai, D. Neuhaus, and G. Varani. 1996. Specificity of ribonucleoprotein interactions determined by RNA folding during complex formation. Nature 380:646-650.
2. Bartos, H. 1995. Ph.D. thesis. University of Heidelberg, Heidelberg, Germany.
3. Beck, J., and M. Nassal. 1996. A sensitive procedure for mapping the boundaries of RNA elements binding in vitro translated proteins defines a minimal hepatitis B virus encapsidation signal. Nucleic Acids Res. 24:4364-4366.
4. Beck, J., and M. Nassal. Unpublished data.
5. Beck, J., H. Bartos, and M. Nassal. 1997. Experimental confirmation of a hepatitis B virus (KBV) ε-like bulge-and-loop structure in avian HBV RNA encapsidation signals. Virology 227:500-504.
6. Bhattacharyya, A., A. I. H. Murchie, and D. M. J. Lilley. 1990. RNA bulges and the helical periodicity of double-stranded RNA. Nature 343:484-487.
7. Calvert, J., and J. Summers. 1994. Two regions of an avian hepadnavirus RNA pregenome are required in cis for encapsidation. J. Virol. 68:2084-2090.
8. Draper, D. E. 1995. Protein-RNA recognition. Annu. Rev. Biochem. 64:593-620.
9. Grüne, M., J. P. Fürste, S. Klußmann, V. A. Erdmann, and L. R. Brown. 1996. Detection of multiple conformations of the E-domain of 5S rRNA from Escherichia coli in solution and in crystals by NMR spectroscopy. Nucleic Acids Res. 24:2592-2590.
10. Hu, J., and C. Seeger. 1996. Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase. Proc. Natl. Acad. Sci. USA 93:1060-1064.
11. Jaffrey, S. R., D. J. Haile, R. U. Klausner, and J. B. Harford. 1993. The interaction between the iron-responsive element binding protein and its cognate RNA is highly dependent upon both RNA sequence and structure. Nucleic Acids Res. 21:4627-4631.
12. Junker-Niepmann, M., R. Bartenschlager, and H. Schaller. 1990. A short cis-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA. EMBO J. 9:3389-3396.
13. Karn, J., M. J. Gait, M. J. Churcher, D. A. Mann, I. Mikaelian, and C. Pritchard. 1995. Control of human immunodeficiency virus gene expression by the RNA binding proteins Tat and Rev, p. 192-220. In K. Nagai and I. Mattaj (ed.), Frontiers in molecular biology: RNA-protein interactions. Oxford University Press, Oxford, United Kingdom.
14. Knapp, G. 1989. Enzymatic approaches to probing of RNA secondary and tertiary structure. Methods Enzymol. 180:192-212.
15. Knaus, T., and M. Nassal. 1993. The encapsidation signal on the hepatitis B virus RNA pregenome forms a stem-loop structure that is critical for its function. Nucleic Acids Res. 21:3967-3975.
16. Kuchino, Y., and S. Nishimura. 1989. Enzymatic RNA sequencing. Methods Enzymol. 180:154-163.
17. Lanford, R. E., L. Norvall, and B. Beames. 1995. Nucleotide priming and reverse transcriptase activity of hepatitis B virus polymerase expressed in insect cells. J. Virol. 59:4431-4439.
18. Laskus, T., J. Rakela, and D. H. Persing. 1994. The stem-loop structure of the cis-encapsidation signal is highly conserved in naturally occurring hepatitis B virus variants. Virology 200:809-812.
19. Mattaj, I. W. 1993. RNA recognition - a family matter? Cell 73:837-840.
20. Nassal, M. 1996. Hepatitis B virus morphogenesis. Curr. Top. Microbiol. Immunol. 214:297-337.
21. Nassal, M., and H. Schaller. 1996. Hepatitis B virus replication - an update. J. Viral Hepatitis 3:217-226.
22. Nassal, M., and A. Rieger. 1996. A bulged region of the hepatitis B virus RNA encapsidation signal contains the replication origin for discontinuous first-strand DNA synthesis. J. Virol. 70:2764-2773.
23. Pollack, J. R., and D. Ganem. 1993. An RNA stem-loop structure directs hepatitis B virus genomic RNA encapsidation. J. Virol. 67:3254-3263.
24. Pollack, J. R., and D. Ganem. 1994. Site-specific RNA binding by a hepatitis B virus reverse transcriptase initiates two distinct reactions: RNA packaging and DNA synthesis. J. Virol. 68:5579-5587.
25. Rieger, A., and M. Nassal. 1995. Distinct requirements for primary sequence in the 5′-and 3′-part of a bulge in the hepatitis B virus RNA encapsidation signal revealed by a combined in vivo selection/in vitro amplification system. Nucleic Acids Res. 23:3309-3315.
26. Rieger, A., and M. Nassal. 1996. Specific hepatitis B virus minus-strand DNA synthesis requires only the 5′ encapsidation signal and the 3′-proximal direct repeat DR1*. J. Virol. 70:585-589.
27. Sumner-Smith, M., S. Roy, R. Barnet, L. S. Reid, R. Kuperman, U. Delling, and N. Sonenberg. 1991. Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein. J. Virol. 65:5196-5202.
28. Tavis, J. E., and D. Ganem. 1993. Expression of functional hepatitis B virus polymerase in yeast reveals it to be the sole viral protein required for correct initiation of reverse transcription. Proc. Natl. Acad. Sci. USA 90:4107-4111.
29. Tavis, J. E., S. Perri, and D. Ganem. 1994. Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer. J. Virol. 68:3536-3543.
30. Tavis, J. E., and D. Ganem. 1995. RNA sequences controlling the initiation and transfer of duck hepatitis B virus minus-strand DNA. J. Virol. 69:4283-4291.
31. Tavis, J. E., and D. Ganem. 1996. Evidence for activation of the hepatitis B virus polymerase by binding of its RNA template. J. Virol. 70:5741-5750.
32. Valegard, K., J. B. Murray, P. G. Stockley, N. J. Stonehouse, and L. Liljas. 1994. Crystal structure of an RNA bacteriophage coat protein-operator complex. Nature 371:623-626.
33. Wang, G. H., and C. Seeger. 1992. The reverse transcriptase of hepatitis B virus acts as a protein primer for viral DNA synthesis. Cell 71:663-670.
34. Wang, G. H., and C. Seeger. 1993. Novel mechanism for reverse transcription in hepatitis B viruses. J. Virol. 67:6507-6512.
35. Wang, G. H., F. Zoulim, E. H. Leber, J. Kitson, and C. Seeger. 1994. Role of RNA in enzymatic activity of the reverse transcriptase of hepatitis B viruses. J. Virol. 68:8437-8442.
36. Weber, M., V. Bronsema, H. Bartos, A. Bosserhoff, R. Bartenschlager, and H. Schaller. 1994. Hepadnavirus P protein utilizes a tyrosine residue in the TP domain to prime reverse transcription. J. Virol. 68:2994-2999.
37. Witherell, G. W., J. M. Gott, and O. C. Uhlenbeck. 1991. Specific interactions between RNA phage coat proteins and RNA. Prog. Nucleic Acid Res. Mol. Biol. 40:185-220.
38. Wu, H. N., and O. C. Uhlenbeck. 1987. Role of a bulged A residue in a specific RNA-protein interaction. Biochemistry 26:8221-8227.
39. Ziermann, R., and D. Ganem. 1996. Homologous and heterologous complementation of HBV and WHV capsid and polymerase functions in RNA encapsidation. Virology 219:350-356.
40. Zuker, M. 1989. On finding all suboptimal foldings of an RNA molecule. Science 244:48-52.