-
1
-
-
85071404714
-
Anti-human immunodeficiency virus type 1 activity of phosphodiester hexadeoxyribonucleotide modified by dibenzyloxybenzyl and hydroxyethyl residues at the 5′- and 3′-ends, R-95288
-
submitted
-
Agatsuma, T., Furukawa, H., Hotoda, H., Koizumi, M., Koga, R. and Kaneko, M. (1997) Anti-human immunodeficiency virus type 1 activity of phosphodiester hexadeoxyribonucleotide modified by dibenzyloxybenzyl and hydroxyethyl residues at the 5′- and 3′-ends, R-95288. Antiviral Res. submitted.
-
(1997)
Antiviral Res.
-
-
Agatsuma, T.1
Furukawa, H.2
Hotoda, H.3
Koizumi, M.4
Koga, R.5
Kaneko, M.6
-
2
-
-
0029878448
-
MDL 74968 a new acyclonucleotide Analog: Activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection
-
Bridges, C.G., Taylor, D.L., Ahmed, P.S., Brennan, T.M., Hornsperger, J.M., Nave, J.F., Casara, P. and Tyms, A.S. (1996) MDL 74968 A new acyclonucleotide Analog: Activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.beige mouse model of infection. Antimicrob. Agents Chemother. 40, 1072-1077.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 1072-1077
-
-
Bridges, C.G.1
Taylor, D.L.2
Ahmed, P.S.3
Brennan, T.M.4
Hornsperger, J.M.5
Nave, J.F.6
Casara, P.7
Tyms, A.S.8
-
3
-
-
0025055096
-
Evaluation of the pregnancy immunotropism hypothesis by assessment of the reproductive performance of young adult mice of genotype scid/scid, bg/bg
-
Croy, B.A. and Chapeau, C. (1990) Evaluation of the pregnancy immunotropism hypothesis by assessment of the reproductive performance of young adult mice of genotype scid/scid, bg/bg. J. Reprod. Fert. 88, 231-239.
-
(1990)
J. Reprod. Fert.
, vol.88
, pp. 231-239
-
-
Croy, B.A.1
Chapeau, C.2
-
4
-
-
0028607441
-
Mechanism of inhibition in vitro by guanine-rich oligonucleotides modified at the 5′terminal with dimethoxytrytyl residues
-
Furukawa, H., Momota, K., Agatsuma, T., Yamamoto, Y., Kimura, S. and Shimada, K. (1994) Mechanism of inhibition in vitro by guanine-rich oligonucleotides modified at the 5′terminal with dimethoxytrytyl residues. Nucleic Acids Res. 22, 5621-5627.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 5621-5627
-
-
Furukawa, H.1
Momota, K.2
Agatsuma, T.3
Yamamoto, Y.4
Kimura, S.5
Shimada, K.6
-
5
-
-
0030797950
-
Identification of a phosphodiester hexaoligonucleotide that inhibit HIV-1 replication in vitro upon covalent linkage of its 5′-end with dimethoxytrytyl residue
-
accepted
-
Furukawa, H., Momota, K., Agatsuma, T., Yamamoto, I., Kimura, S. and Shimada, K. (1997) Identification of a phosphodiester hexaoligonucleotide that inhibit HIV-1 replication in vitro upon covalent linkage of its 5′-end with dimethoxytrytyl residue, Antisense Res. Dev., accepted.
-
(1997)
Antisense Res. Dev.
-
-
Furukawa, H.1
Momota, K.2
Agatsuma, T.3
Yamamoto, I.4
Kimura, S.5
Shimada, K.6
-
6
-
-
0028950509
-
Pre- and post exposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody
-
Gauduin, M.-C., Safrit, J.T., Weir, R. Fung, M.S.C. and Koup, R.A. (1995) Pre- and post exposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody. J. Infect. Dis. 171, 1203-1209.
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1203-1209
-
-
Gauduin, M.-C.1
Safrit, J.T.2
Weir, R.3
Fung, M.S.C.4
Koup, R.A.5
-
7
-
-
85071406818
-
Biologically active oligonucleotides-VI: Structure-activity relationships of anti-HIV-1 hexadeoxyribonucleotides bearing 3′- and 5′-end-modifications
-
Koga, R., Koizumi, M., Hotoda, H., Momota, K., Ohmine, T., Furukawa, H., Nishigaki, T., Kosaka, T. and Kaneko, M. (1996) Biologically active oligonucleotides-VI: Structure-activity relationships of anti-HIV-1 hexadeoxyribonucleotides bearing 3′- and 5′-end-modifications. Antiviral Res. (9th International Conference on Antiviral Research), 47, A32.
-
(1996)
Antiviral Res. (9th International Conference on Antiviral Research)
, vol.47
-
-
Koga, R.1
Koizumi, M.2
Hotoda, H.3
Momota, K.4
Ohmine, T.5
Furukawa, H.6
Nishigaki, T.7
Kosaka, T.8
Kaneko, M.9
-
8
-
-
0027945247
-
Cloned human CD8+ cytotoxic T lymphocytes protect human peripheral blood leukocyte-severe combined immunodeficient mice from HIV-1 infection by an HLA-unrestricted mechanism
-
Kuyk, R., Torbett, B.E. Gulizia, R.J., Leath, S., Mosier, D.E. and Koenig, S. (1994) Cloned human CD8+ cytotoxic T lymphocytes protect human peripheral blood leukocyte-severe combined immunodeficient mice from HIV-1 infection by an HLA-unrestricted mechanism. J. Immunol. 153, 4826-4833.
-
(1994)
J. Immunol.
, vol.153
, pp. 4826-4833
-
-
Kuyk, R.1
Torbett, B.E.2
Gulizia, R.J.3
Leath, S.4
Mosier, D.E.5
Koenig, S.6
-
9
-
-
0025729443
-
Quantitative assessment of HIV-1 DNA load by coamplification of HIV-1 gag and HLA-DQ-α genes
-
Lee, T-H, Sunzeri, F.J., Tobler, L.H., Williams, B.G. and Busch, M.P. (1991) Quantitative assessment of HIV-1 DNA load by coamplification of HIV-1 gag and HLA-DQ-α genes. AIDS, 5, 683-691.
-
(1991)
AIDS
, vol.5
, pp. 683-691
-
-
Lee, T.-H.1
Sunzeri, F.J.2
Tobler, L.H.3
Williams, B.G.4
Busch, M.P.5
-
10
-
-
0024505583
-
Stepwise mechanism of HIV reverse transcriptase: Primer function of phosphorothioate oligodeoxynucleotide
-
Majumdar, C., Stein, C.A., Cohen, J.S., Broder, S. and Wilson, S.H. (1989) Stepwise mechanism of HIV reverse transcriptase: primer function of phosphorothioate oligodeoxynucleotide. Biochemistry, 28, 1340-1346.
-
(1989)
Biochemistry
, vol.28
, pp. 1340-1346
-
-
Majumdar, C.1
Stein, C.A.2
Cohen, J.S.3
Broder, S.4
Wilson, S.H.5
-
11
-
-
0000600241
-
Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligonucleotide against rev (art/trs) in chronically infected cells
-
Matsukura, M., Zon, G., Shinozuka, K., Robert-Guroff, M., Shimada, T., Stein, C.A., Mitsuya, H., Wong-Staal, F., Cohen, J.S. and Broder, S. (1989) Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligonucleotide against rev (art/trs) in chronically infected cells. Proc. Natl. Sci. USA, 86, 4244-4249.
-
(1989)
Proc. Natl. Sci. USA
, vol.86
, pp. 4244-4249
-
-
Matsukura, M.1
Zon, G.2
Shinozuka, K.3
Robert-Guroff, M.4
Shimada, T.5
Stein, C.A.6
Mitsuya, H.7
Wong-Staal, F.8
Cohen, J.S.9
Broder, S.10
-
12
-
-
0023734130
-
Transfer of a functional immune system to mice with severe combined immunodeficiency
-
Mosier, D.E., Gulizia, R.J., Baird, S.M. and Wilson, D.B. (1988) Transfer of a functional immune system to mice with severe combined immunodeficiency. Nature 335, 256-259.
-
(1988)
Nature
, vol.335
, pp. 256-259
-
-
Mosier, D.E.1
Gulizia, R.J.2
Baird, S.M.3
Wilson, D.B.4
-
13
-
-
0025907920
-
Human immunodeficiency virus infection of hu-PBL-SCID mice
-
Mosier, D.E., Gulizia, R.J., Baird, S.M., Wilson, D.B., Spector D.H. and Spector, S.A. (1991) Human immunodeficiency virus infection of hu-PBL-SCID mice. Science 251, 791-794.
-
(1991)
Science
, vol.251
, pp. 791-794
-
-
Mosier, D.E.1
Gulizia, R.J.2
Baird, S.M.3
Wilson, D.B.4
Spector, D.H.5
Spector, S.A.6
-
14
-
-
0027408497
-
Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160
-
Mosier, D.E., Gulizia, R.J., MacIsaac, P.D., Corey, L. and Greenberg, P.D. (1993) Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160. Proc. Natl. Acad. Sci. USA, 90, 2443-2447.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2443-2447
-
-
Mosier, D.E.1
Gulizia, R.J.2
MacIsaac, P.D.3
Corey, L.4
Greenberg, P.D.5
-
15
-
-
0028058841
-
Macrophage-tropic HIV: Critical for AIDS pathogenesis?
-
Mosier, D.E. and Sieberg, H. (1994) Macrophage-tropic HIV: critical for AIDS pathogenesis? Immunol. Today, 15, 332-339.
-
(1994)
Immunol. Today
, vol.15
, pp. 332-339
-
-
Mosier, D.E.1
Sieberg, H.2
-
16
-
-
0028342861
-
Inhibition of human immunodeficiency virus type 1 activity in vitro by oligonucleotides composed entirely of guanosine and thymidine
-
Ojwang, J., Elbaggari, A., Marshall, H.B., Jayaraman, K., McGrath, M.S. and Rando, R.F. (1994) Inhibition of human immunodeficiency virus type 1 activity in vitro by oligonucleotides composed entirely of guanosine and thymidine. J Acq. Immune. Defic. Syndr. 7(6), 560-570.
-
(1994)
J Acq. Immune. Defic. Syndr.
, vol.7
, Issue.6
, pp. 560-570
-
-
Ojwang, J.1
Elbaggari, A.2
Marshall, H.B.3
Jayaraman, K.4
McGrath, M.S.5
Rando, R.F.6
-
17
-
-
0029058337
-
Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against gp120 CD4 binding site
-
Parren, P.W., Ditzel, H.D., Gulizia, R.J., Binley, J.M., Barbas, C., Burton, D.R. and Mosier, D.E. (1995) Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against gp120 CD4 binding site., AIDS 9, F1-6.
-
(1995)
AIDS
, vol.9
-
-
Parren, P.W.1
Ditzel, H.D.2
Gulizia, R.J.3
Binley, J.M.4
Barbas, C.5
Burton, D.R.6
Mosier, D.E.7
-
18
-
-
0027537122
-
hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal anitibody to the principal neutralizing determinant of envelope gp120
-
Safrit, J.T., Fung, M.S.C., Andrews, C.A., Braun, D.G., Sun, W.N.C., Chang, T.W. and Koup, R.A. (1993) hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal anitibody to the principal neutralizing determinant of envelope gp120. AIDS 7, 15-21.
-
(1993)
AIDS
, vol.7
, pp. 15-21
-
-
Safrit, J.T.1
Fung, M.S.C.2
Andrews, C.A.3
Braun, D.G.4
Sun, W.N.C.5
Chang, T.W.6
Koup, R.A.7
-
19
-
-
0026058794
-
Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 gp120 to CD4
-
Stein, C.A., Neckers, L.M., Nair, B.C., Mumbauer, S., Hoke, G. and Pal, R. (1991) Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 gp120 to CD4. J. Acq. Immune. Defic. Syndr. 4, 686-693.
-
(1991)
J. Acq. Immune. Defic. Syndr.
, vol.4
, pp. 686-693
-
-
Stein, C.A.1
Neckers, L.M.2
Nair, B.C.3
Mumbauer, S.4
Hoke, G.5
Pal, R.6
-
20
-
-
0028806487
-
Does antisense exist?
-
Stein, C.A, 1995, Does antisense exist? Nature Medicine 1, 1119-1121.
-
(1995)
Nature Medicine
, vol.1
, pp. 1119-1121
-
-
Stein, C.A.1
-
21
-
-
0026357869
-
hu-PBL-SCID mice: A model for human immune function, AIDS, and lymphomagenesis
-
Torbett, B.E., Picchio, G. and Mosier, D.E. (1991) hu-PBL-SCID mice: a model for human immune function, AIDS, and lymphomagenesis. Immunological Rev., 124, 139-164.
-
(1991)
Immunological Rev.
, vol.124
, pp. 139-164
-
-
Torbett, B.E.1
Picchio, G.2
Mosier, D.E.3
-
22
-
-
0027383518
-
Effect of dosing frequency on ZDV prophylaxis in macaques infected with simian immunodeficiency virus
-
Tsai, C.C., Follis, K.E., Grant, R.F., Nolte, R.E., Barts, C.R., Benveniste, R.E. and Sager, P.R. (1993) Effect of dosing frequency on ZDV prophylaxis in macaques infected with simian immunodeficiency virus. J. Acq. Immune Defic. Syndr. 6, 1086-1092.
-
(1993)
J. Acq. Immune Defic. Syndr.
, vol.6
, pp. 1086-1092
-
-
Tsai, C.C.1
Follis, K.E.2
Grant, R.F.3
Nolte, R.E.4
Barts, C.R.5
Benveniste, R.E.6
Sager, P.R.7
-
23
-
-
15844427103
-
Antiviral agents reduce viral load and delay the detection of infected cells in vivo in the HIV-infected hu-PBMC SCID mouse model
-
Ussery, M.A., Broud, D.D., Wood, O.L., Kunder, S.C., Black, P.L., Dailey, P.C., Wilber, J.C., Yang. L., Piatek, M.Jr. and Lifson, J.D. (1995) Antiviral agents reduce viral load and delay the detection of infected cells in vivo in the HIV-infected hu-PBMC SCID mouse model. Antiviral Res. (8th International Conference on Antiviral Research), 26, A238.
-
(1995)
Antiviral Res. (8th International Conference on Antiviral Research)
, vol.26
-
-
Ussery, M.A.1
Broud, D.D.2
Wood, O.L.3
Kunder, S.C.4
Black, P.L.5
Dailey, P.C.6
Wilber, J.C.7
Yang, L.8
Piatek M., Jr.9
Lifson, J.D.10
-
24
-
-
0013610644
-
Antiviral ativity of the protease inhibitor KNI-272 in vivo in the HIV-infected HuPBMC-SCID mouse Model
-
Ussery, M.A., Wood, O.L., Broud, D.D., Bacho, M., Kunder, S.C., Papermaster, S., Kiso, Y. and Black, P.L (1996) Antiviral ativity of the protease inhibitor KNI-272 in vivo in the HIV-infected HuPBMC-SCID mouse Model. Antiviral Res. (9th International Conference on Antiviral Research), 6, A18.
-
(1996)
Antiviral Res. (9th International Conference on Antiviral Research)
, vol.6
-
-
Ussery, M.A.1
Wood, O.L.2
Broud, D.D.3
Bacho, M.4
Kunder, S.C.5
Papermaster, S.6
Kiso, Y.7
Black, P.L.8
-
25
-
-
0007782268
-
Analysis of stereo structure of anti-HIV-1 oligonucleotide, S-1443 (R-95288)
-
3-P-0284
-
Watanabe, T., Hanzawa, H., Haruyama, H., Koizumi, M. and Kaneko, M. (1996) Analysis of stereo structure of anti-HIV-1 oligonucleotide, S-1443 (R-95288). Seikagaku, 68, 941, 3-P-0284.
-
(1996)
Seikagaku
, vol.68
, pp. 941
-
-
Watanabe, T.1
Hanzawa, H.2
Haruyama, H.3
Koizumi, M.4
Kaneko, M.5
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