MDL 74,968, a new acyclonucleotide analog: Activity against human immunodeficiency virus in vitro and in the hu-PBL-SCID.Beige mouse model of infection

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 5, 1996, Pages 1072-1077

  Bridges, C G ^a,c   Taylor, D L ^a   Ahmed, P S ^a   Brennan, T M ^a   Hornsperger, J M ^b   Nave J F ^b   Casara, P ^b   Tyms, A S ^a  

^a Med Res Cncl Collaborative Centre   (United Kingdom)

^b SANOFI   (France)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

9 [2 METHYLIDENE 3 (PHOSPHONOMETHOXY)PROPYL]GUANINE; ACYCLIC NUCLEOSIDE; ADEFOVIR; DIDANOSINE; GUANINE DERIVATIVE; NEW DRUG; PRODRUG; UNCLASSIFIED DRUG; VIRUS DNA; ZIDOVUDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISEASE SEVERITY; DOSE RESPONSE; DRUG BIOAVAILABILITY; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROVIRUS; SPLEEN CELL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029878448     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.5.1072     Document Type: Article

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