Influence of dietary arachidonic acid on metabolism in vivo of 8cis,11cis,14-eicosatrienoic acid in humans

Lipids

Volumn 32, Issue 4, 1997, Pages 441-448

  Emken, E A ^a   Adlof, R O ^a   Duval, S M ^a   Nelson, G J ^b  

^a NATIONAL CENTER FOR AGRICULTURAL UTILIZATION RESEARCH   (United States)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; ICOSATRIENOIC ACID;

ADULT; CONFERENCE PAPER; DIET SUPPLEMENTATION; DIETARY INTAKE; ENZYME ANALYSIS; FAT INTAKE; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; ICOSANOID METABOLISM; LIPID ANALYSIS; LIPID COMPOSITION; LIPID DIET; MALE; MASS SPECTROMETRY; NORMAL HUMAN;

EID: 0030902314     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-997-0058-4     Document Type: Conference Paper

References (39)

1. Horrobin, D.F. (1992) Nutritional and Medical Importance of Gamma-Linolenic Acid, Prog. Lipid Res. 31, 163-194.
2. Horrobin, D.F. (ed.) (1990) Omega-6 Essential Fatty Acids. Pathology and Roles in Clinical Medicine, Alan R. Liss, Inc. New York.
3. Sardesai, V.M. (1992) Nutritional Role of Polyunsaturated Fatty Acids, J. Nutr. Biochem. 3, 154-166.
4. Huang, Y.-S., and Mills, D.E. (eds.) (1996) in γ-Linolenic Acid: Metabolism and Its Roles in Nutrition and Medicine, AOCS Press, Champaign.
5. Huang, Y.-S., Mills, D.E., Cantrill, R.C., and Poisson, J.-P. (1996) In vivo and in vitro Metabolism of Linoleic and γ-Linolenic acids, in γ-Linolenic Acid: Metabolism and Its Roles in Nutrition and Medicine (Huang, Y.-S., and Mills, D.E., eds.) pp. 84-105, AOCS Press, Champaign.
6. Stone, K.J., Willis, A.L., Hart, M., Kirtland, S.J., Kernoff, P.B.A., and McNicol, G.P. (1979) The Metabolism of Dihomoγ-Linolenic Acid in Man, Lipids 14, 174-180.
7. Boustani, S.E., Causse, J.E., Descomps, B., Monnier, L., Mendy, F., and de Paulet, A.C. (1989) Direct in vivo Characterization of Delta 5 Desaturase Activity in Humans by Deuterium Labeling: Effect of Insulin, Metabolism 38, 315-321.
8. Emken, E.A., Rohwedder, W.K., Dutton, H.J., Dougherty, R., Iacono, J.M., and Mackin, J. (1975) Dual-Labeled Technique for Human Lipid Metabolism Studies Using Deuterated Fatty Acid Isomers, Lipids 11, 135-142.
9. Rakoff, H. (1988) Preparation of Methyl cis-9,cis-12,cis-15-octadecatrienoate-15,16-d2 and Methyl cis-9,cis-12,cis-15-octadecatrienoate-6,6,7,7-d4, Lipids 23, 280-285.
10. Christie, W.W. (1973) Lipid Analysis, pp. 85-102, Pergamon Press Ltd., New York.
11. Nelson, G.J., Kelley, D.S., Emken, E.A., Phinney, S.D., Kyle, D., and Ferretti, A. (1997) A Human Dietary Arachidonic Acid Supplementation Study Conducted in a Metabolic Research Unit: Rationale and Design, Lipids 32, 415-420.
12. USDA Handbook 8, 1-23. Composition of Foods, Raw, Processed, Prepared. Releases and Supplements (1976-present). Nutrient Data Laboratory/Agricultural Research Service, Riverdale, MO.
13. Lindgren, F.T., Jensen, L.C., and Hatch, F.T. (1972) The Isolation and Quantitative Analysis of Serum Lipoproteins, in Blood Lipids and Lipoproteins (Nelson, G.J., ed.) pp. 186-188, Wiley-Interscience, New York.
14. Narayan, K.A. (1975) Electrophoresis Methods for the Separation of Serum Lipoproteins, in Analysis of Lipids and Lipoproteins (Perkins, E.G., ed.) pp. 225-249, American Oil Chemists' Society, Champaign.
15. Folch, J., Lees, M., and Sloane-Stanley, G.E.. (1957) A Simple Method for the Isolation and Purification of Total Lipids from Animal Tissues, J. Biol. Chem. 226, 497-509.
16. French, J.A., and Anderson, D.W. (1973) Separation and Quantitative Recovery of Lipid Classes: A Convenient Thin-Layer Chromatographic Method, J. Chromatogr. 80, 133-136.
17. Peter, H.W., and Wolf, H.U. (1973) A New Method for the in situ Determination of Phospholipids After Thin-Layer Separation, J. Chromatogr. 82, 15-30.
18. Schenck, P.A., Rakoff, H., and Emken, E.A. (1996) Δ8 Desaturation in vivo of Deuterated Eicosatrienoic Acid by Mouse Liver, Lipids 31, 593-600.
19. Rohwedder, W.K., Emken, E.A., and Wolf, D.J. (1985) Analysis of Deuterium-Labeled Blood Lipids by Chemical Ionization Mass Spectrometry, Lipids 20, 303-311.
20. Statistical Analysis System Institute (1987) SAS Guide for Personal Computers, 6th edn., SAS Institute Inc., Cary.
21. Emken, E.A., Adlof, R.O., Rohwedder, W.K., and Gulley, R.M. (1993) Influence of Linoleic Acid on Desaturation and Uptake of Deuterium-Labeled Palmitic and Stearic Acids in Humans, Biochim. Biophys. Acta 1170, 173-181.
22. Nelson, G.J., Schmidt, P.C., Bartolini, G., Kelley, D.S., Phinney, S.D., Kyle, D., Silbermann, S., and Schaefer, E.J. (1997) The Effect of Dietary Arachidonic Acid on Plasma Lipoprotein Distributions, Apoproteins, Blood Lipid Levels, and Tissue Fatty Acid Composition in Humans, Lipids 32, 427-433.
23. Nelson, G.J., and Ackman, R.G. (1988) Absorption and Transport of Fat in Mammals with Emphasis on n-3 Polyunsaturated Fatty Acids, Lipids 23, 1005-1014.
24. Nordoy, A., Barstad, L., Connor, W.E., and Hatcher, L. (1991) Absorption of the n-3 Eicosapentaenoic and Docosahexaenoic Acids as Ethyl Esters and Triglycerides by Humans, Am. J. Clin. Nutr. 53, 1185-1190.
25. Chernenko, G.A., Barrowman, J.A., Kean, K.T., Herzberg, G.R., and Keough, K.M.W. (1989) Intestinal Absorption and Lymphatic Transport of Fish Oil (MaxEPA) in the Rat, Biochim. Biophys. Acta 1004, 95-102.
26. Hamazaki, T., Urakaze, M., Makuta, M., Ozawa, A., Soda, Y., Tatsum, H., Yano, S., and Kumagai, A. (1987) Intake of Different Eicosapentaenoic Acid-Containing Lipids and Fatty Acid Pattern of Plasma Lipids in the Rats, Lipids 22, 994-998.
27. Krokan, H.E., Bjerve, K.S., and Mork, E. (1993) The Enteral Bioavailability of Eicosapentaenoic Acid and Docosahexaenoic Acid Is as Good from Ethyl Esters as from Glyceryl Esters in Spite of Lower Hydrolytic Rates by Pancreatic Lipase in vitro, Biochim. Biophys. Acta 1168, 59-67.
28. Nilsson, A., and Melin, T. (1988) Absorption and Metabolism of Orally Fed Arachidonic and Linoleic Acid in the Rat. Am. J. Physiology 255, G612-G618
29. Chen, I.S., Hotta, S., Ikeda, I., Cassidy, M.M., Sheppard, A.J., and Vahouny, G.V. (1987) Digestion, Absorption and Effects on Cholesterol Absorption of Menhaden Oil, Fish Oil Concentrate and Corn Oil by Rats, J. Nutr. 117, 1676-1680.
30. Lawson, L.D., and Hughes, B.G. (1988) Human Absorption of Fish Oil Fatty Acids as Triacylglycerols, Free Acids, or Ethyl Esters, Biochem. Biophys. Res. Comm. 152, 328-335.
31. 14C]Dihomo-gamma-linolenic Acids, Biochem. Med. Metab. Biol. 49, 57-66.
32. Emken, E.A., Adlof, R.O., and Gulley, R.M. (1994) Dietary Linoleic Acid Influences Desaturation and Acylation of Deuterium-Labeled Linoleic and Linolenic Acids in Young Adult Males, Biochim. Biophys. Acta 1213, 277-288.
33. Barre, D.E., and Holub, B.J. (1992) The Effect of Borage Oil Consumption on Human Plasma Lipid Levels and the Phosphatidylcholine and Cholesterol Ester Composition of High Density Lipoprotein, Nutr. Res. 12, 1181-1194.
34. Berger, A., and German, J.B. (1990) Phospholipid Fatty Acid Comparison of Various Mouse Tissues After Feeding α-Linolenate (18:3n-3) or Eicosatrienoate (20:3n-3), Lipids 25, 473-480
35. Cook, H.W., Clarke, J.T.R., and Spence, W. (1983) Concerted Stimulation and Inhibition of Desaturation, Chain Elongation, and Esterification of Essential Fatty Acids by Cultured Neuroblastoma Cells, J. Biol. Chem. 258, 7587-7591.
36. Cook, H.W., and Spence, M.W. (1987) Studies of the Modulation of Essential Fatty Acid Metabolism by Fatty Acids in Cultured Neuroblastoma and Glioma Cells, Biochim. Biophys. Acta 918, 217-229
37. Chen, Q., and Nilsson, A. (1993) Desaturation and Chain Elongation of n-3 and n-6 Polyunsaturated Fatty Acids in the Human CaCo-2 Cell Lines, Biochim. Biophys. Acta 1166, 193-201.
38. Pugh, E.L., and Kates, M. (1977) Direct Desaturation of Eicosatrienoyl Lecithin to Arachidonoyl Lecithin by Rat Liver Microsomes, J. Biol. Chem. 252, 68-73.
39. Luthria, D., and Sprecher, H. (1994) A Comparison of the Specific Activities of Linoleate and Arachidonate in Liver, Heart, and Kidney Phospholipids After Feeding Rats Ethyl Linoleate-9,10,12,13-d4, Biochim. Biophys. Acta 1213, 1-4.