Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis

Biochemistry

Volumn 35, Issue 22, 1996, Pages 7084-7092

  Hengge, Alvan C ^a   Denu, John M ^b   Dixon, Jack E ^b  

^a UNIVERSITY OF WISCONSIN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASE; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CELL DIFFERENTIATION; DEPHOSPHORYLATION; ENZYME CONFORMATION; ENZYME STRUCTURE; GENE MUTATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; SIGNAL TRANSDUCTION;

CATALYSIS; HUMANS; HYDROLYSIS; KINETICS; MASS SPECTROMETRY; MODELS, CHEMICAL; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MUTATION; NITROGEN ISOTOPES; NITROPHENOLS; ORGANOPHOSPHORUS COMPOUNDS; OXYGEN ISOTOPES; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT PROTEINS;

EID: 0029994512     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960255i     Document Type: Article

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